ATE472597T2 - Kontrollierte glukosezufuhr für tierzellkultur - Google Patents

Kontrollierte glukosezufuhr für tierzellkultur Download PDF

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Publication number
ATE472597T2
ATE472597T2 AT04752591T AT04752591T ATE472597T2 AT E472597 T2 ATE472597 T2 AT E472597T2 AT 04752591 T AT04752591 T AT 04752591T AT 04752591 T AT04752591 T AT 04752591T AT E472597 T2 ATE472597 T2 AT E472597T2
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AT
Austria
Prior art keywords
glucose
cell culture
feeding
restricted
rate
Prior art date
Application number
AT04752591T
Other languages
English (en)
Inventor
Denis Drapeau
Terry Stanek
Yen-Tung Luan
Original Assignee
Wyeth Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33476770&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE472597(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Llc filed Critical Wyeth Llc
Application granted granted Critical
Publication of ATE472597T2 publication Critical patent/ATE472597T2/de

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/34—Sugars

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Fodder In General (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT04752591T 2003-05-15 2004-05-17 Kontrollierte glukosezufuhr für tierzellkultur ATE472597T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47093703P 2003-05-15 2003-05-15
PCT/US2004/015597 WO2004104186A1 (en) 2003-05-15 2004-05-17 Restricted glucose feed for animal cell culture

Publications (1)

Publication Number Publication Date
ATE472597T2 true ATE472597T2 (de) 2010-07-15

Family

ID=33476770

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04752591T ATE472597T2 (de) 2003-05-15 2004-05-17 Kontrollierte glukosezufuhr für tierzellkultur

Country Status (10)

Country Link
US (1) US7429491B2 (de)
EP (1) EP1623019B2 (de)
AT (1) ATE472597T2 (de)
DE (1) DE602004027905D1 (de)
DK (1) DK1623019T4 (de)
ES (1) ES2344789T5 (de)
PL (1) PL1623019T5 (de)
PT (1) PT1623019E (de)
SI (1) SI1623019T1 (de)
WO (1) WO2004104186A1 (de)

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CN105189735B (zh) 2011-04-29 2019-04-12 拜康研究有限公司 在培养期间减少乳酸累积的方法和生产多肽的方法
US9067990B2 (en) 2013-03-14 2015-06-30 Abbvie, Inc. Protein purification using displacement chromatography
WO2013158273A1 (en) 2012-04-20 2013-10-24 Abbvie Inc. Methods to modulate c-terminal lysine variant distribution
US9334319B2 (en) 2012-04-20 2016-05-10 Abbvie Inc. Low acidic species compositions
WO2013176754A1 (en) 2012-05-24 2013-11-28 Abbvie Inc. Novel purification of antibodies using hydrophobic interaction chromatography
US9512214B2 (en) 2012-09-02 2016-12-06 Abbvie, Inc. Methods to control protein heterogeneity
CA2883272A1 (en) 2012-09-02 2014-03-06 Abbvie Inc. Methods to control protein heterogeneity
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US9017687B1 (en) 2013-10-18 2015-04-28 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same using displacement chromatography
US8921526B2 (en) 2013-03-14 2014-12-30 Abbvie, Inc. Mutated anti-TNFα antibodies and methods of their use
US9499614B2 (en) 2013-03-14 2016-11-22 Abbvie Inc. Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosaccharides
AR095196A1 (es) 2013-03-15 2015-09-30 Regeneron Pharma Medio de cultivo celular libre de suero
EP2972238B1 (de) 2013-03-15 2023-04-26 Biogen MA Inc. Verwendung von raman-spektroskopie zur überwachung eines kulturmediums
MX363403B (es) 2013-07-04 2019-03-22 Hoffmann La Roche Inmumoensayo con interferencia suprimida para la deteccion de anticuerpos anti-farmacos en muestras de suero.
US9598667B2 (en) 2013-10-04 2017-03-21 Abbvie Inc. Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
KR102243980B1 (ko) 2013-10-11 2021-04-26 리제너론 파마슈티칼스 인코포레이티드 대사적으로 최적화된 세포 배양
US11390663B2 (en) 2013-10-11 2022-07-19 Regeneron Pharmaceuticals, Inc. Metabolically optimized cell culture
US8946395B1 (en) 2013-10-18 2015-02-03 Abbvie Inc. Purification of proteins using hydrophobic interaction chromatography
US9181337B2 (en) 2013-10-18 2015-11-10 Abbvie, Inc. Modulated lysine variant species compositions and methods for producing and using the same
US9085618B2 (en) 2013-10-18 2015-07-21 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same
WO2015073884A2 (en) 2013-11-15 2015-05-21 Abbvie, Inc. Glycoengineered binding protein compositions
EP3119876B1 (de) 2014-03-19 2024-12-18 Pfizer Inc. Zellkultur-verfahren
EP3164481A4 (de) 2014-07-02 2018-03-21 Biogen MA Inc. Skalenübergreifende modellierung von bioreaktorkulturen mittels raman-spektroskopie
WO2016196315A2 (en) * 2015-05-29 2016-12-08 Biogen Ma Inc. Cell culture methods and systems
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MX2020009907A (es) 2018-03-26 2020-10-14 Amgen Inc Glicoformas afucosiladas totales de anticuerpos producidos en cultivo celular.
US11358984B2 (en) 2018-08-27 2022-06-14 Regeneran Pharmaceuticals, Inc. Use of Raman spectroscopy in downstream purification
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CA3121884A1 (en) 2018-12-06 2020-06-11 Pfizer Inc. Cells with reduced inhibitor production and methods of use thereof
EP4045628A4 (de) * 2019-10-18 2024-08-28 Janssen Biotech, Inc. Dynamische monosaccharid-steuerverfahren
US12297451B1 (en) 2019-10-25 2025-05-13 Regeneron Pharmaceuticals, Inc. Cell culture medium
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JP2022060169A (ja) * 2020-10-02 2022-04-14 ファイザー・インク Ｒｓｖ ｆタンパク質生産のための細胞培養工程
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DE10255508A1 (de) * 2002-11-27 2004-06-17 Forschungszentrum Jülich GmbH Verfahren zur Kultivierung von Zellen zur Produktion von Substanzen

Also Published As

Publication number Publication date
ES2344789T3 (es) 2010-09-07
PT1623019E (pt) 2010-07-20
EP1623019B2 (de) 2017-01-25
ES2344789T5 (es) 2017-06-14
EP1623019B1 (de) 2010-06-30
WO2004104186A1 (en) 2004-12-02
PL1623019T5 (pl) 2018-02-28
US20050070013A1 (en) 2005-03-31
DE602004027905D1 (de) 2010-08-12
DK1623019T4 (en) 2017-03-27
DK1623019T3 (da) 2010-09-27
EP1623019A1 (de) 2006-02-08
US7429491B2 (en) 2008-09-30
PL1623019T3 (pl) 2010-10-29
SI1623019T1 (sl) 2010-10-29

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