ATE471326T1 - Substituierte thienopyrrolcarbonsäureamide, pyrrolothiazolcarbonsäureamide und verwandte analoga als inhibitoren von caseinkinase-i- epsilon - Google Patents
Substituierte thienopyrrolcarbonsäureamide, pyrrolothiazolcarbonsäureamide und verwandte analoga als inhibitoren von caseinkinase-i- epsilonInfo
- Publication number
- ATE471326T1 ATE471326T1 AT05826812T AT05826812T ATE471326T1 AT E471326 T1 ATE471326 T1 AT E471326T1 AT 05826812 T AT05826812 T AT 05826812T AT 05826812 T AT05826812 T AT 05826812T AT E471326 T1 ATE471326 T1 AT E471326T1
- Authority
- AT
- Austria
- Prior art keywords
- acid amides
- thienopyrrolencarbononic
- caseinkinase
- carbononic
- analogas
- Prior art date
Links
- 150000001408 amides Chemical class 0.000 title 2
- GBJCWBWQIQXFLH-UHFFFAOYSA-N 2h-pyrrolo[2,3-d][1,3]thiazole Chemical compound C1=NC2=NCSC2=C1 GBJCWBWQIQXFLH-UHFFFAOYSA-N 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60334704P | 2004-08-19 | 2004-08-19 | |
| PCT/US2005/029383 WO2006021000A2 (en) | 2004-08-19 | 2005-08-18 | Substituted thienopyrrole carboxylic acid amides, pyrrolothiazole carboxylic acid amides, and related analogs as inhibitors of casein kinase i epsilon |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE471326T1 true ATE471326T1 (de) | 2010-07-15 |
Family
ID=35695546
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05826812T ATE471326T1 (de) | 2004-08-19 | 2005-08-18 | Substituierte thienopyrrolcarbonsäureamide, pyrrolothiazolcarbonsäureamide und verwandte analoga als inhibitoren von caseinkinase-i- epsilon |
Country Status (30)
| Country | Link |
|---|---|
| US (2) | US7393867B2 (enExample) |
| EP (1) | EP1784409B1 (enExample) |
| JP (1) | JP4869232B2 (enExample) |
| KR (1) | KR20070045263A (enExample) |
| CN (1) | CN100562521C (enExample) |
| AR (1) | AR051008A1 (enExample) |
| AT (1) | ATE471326T1 (enExample) |
| AU (1) | AU2005272584B2 (enExample) |
| BR (1) | BRPI0514419A (enExample) |
| CA (1) | CA2577879C (enExample) |
| CY (1) | CY1110775T1 (enExample) |
| DE (1) | DE602005021889D1 (enExample) |
| DK (1) | DK1784409T3 (enExample) |
| ES (1) | ES2347166T3 (enExample) |
| GT (1) | GT200500215A (enExample) |
| HR (1) | HRP20100475T1 (enExample) |
| IL (1) | IL181158A0 (enExample) |
| JO (1) | JO2629B1 (enExample) |
| MY (1) | MY139831A (enExample) |
| PA (1) | PA8642801A1 (enExample) |
| PE (1) | PE20060630A1 (enExample) |
| PL (1) | PL1784409T3 (enExample) |
| PT (1) | PT1784409E (enExample) |
| RS (1) | RS51413B (enExample) |
| RU (1) | RU2403257C2 (enExample) |
| SI (1) | SI1784409T1 (enExample) |
| SV (1) | SV2006002190A (enExample) |
| TW (1) | TWI372149B (enExample) |
| UY (1) | UY29077A1 (enExample) |
| WO (1) | WO2006021000A2 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2004312530A1 (en) | 2003-12-29 | 2005-07-21 | Sepracor Inc. | Pyrrole and pyrazole DAAO inhibitors |
| US8053603B2 (en) | 2006-01-06 | 2011-11-08 | Sunovion Pharmaceuticals Inc. | Tetralone-based monoamine reuptake inhibitors |
| CA2636324C (en) | 2006-01-06 | 2012-03-20 | Sepracor Inc. | Cycloalkylamines as monoamine reuptake inhibitors |
| AU2007233041B2 (en) | 2006-03-31 | 2013-05-02 | Sepracor Inc. | Preparation of chiral amides and amines |
| US7884124B2 (en) | 2006-06-30 | 2011-02-08 | Sepracor Inc. | Fluoro-substituted inhibitors of D-amino acid oxidase |
| US7902252B2 (en) | 2007-01-18 | 2011-03-08 | Sepracor, Inc. | Inhibitors of D-amino acid oxidase |
| EP1955699A1 (en) * | 2007-02-08 | 2008-08-13 | Boehringer Ingelheim Pharma GmbH & Co. KG | Use of flibanserin for the treatment of insomnia |
| JP5420534B2 (ja) | 2007-05-31 | 2014-02-19 | サノビオン ファーマシューティカルズ インク | モノアミン再取り込み阻害薬としてのフェニル置換シクロアルキルアミン |
| EP2397481B1 (en) * | 2009-02-12 | 2014-03-12 | Pharmadesign, Inc. | Inhibitor of casein kinase 1delta and casein kinase 1epsilon |
| EP2435443B1 (en) * | 2009-05-28 | 2013-07-31 | Vertex Pharmaceuticals Incorporated | Aminopyrazole triazolothiadiazole inhibitors of c-met protien kinase |
| HRP20140252T1 (hr) * | 2009-10-28 | 2014-04-25 | Pfizer Inc. | Derivati imidazola kao inhibitori kazeinske kinaze |
| DE102009058280A1 (de) * | 2009-12-14 | 2011-06-16 | Merck Patent Gmbh | Thiazolderivate |
| RU2562833C2 (ru) | 2010-08-09 | 2015-09-10 | НБ Хелс Лаборатори Ко. Лтд. | Ингибитор казеинкиназы 1 дельта и казеинкиназы 1 е |
| CN109748927A (zh) * | 2017-11-03 | 2019-05-14 | 上海交通大学医学院附属瑞金医院 | 杂芳基酰胺类化合物、其制备方法、药用组合物及其应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9702001D0 (sv) * | 1997-05-28 | 1997-05-28 | Astra Pharma Prod | Novel compounds |
| WO2000075669A1 (en) * | 1999-06-08 | 2000-12-14 | Aventis Pharmaceuticals Inc. | Screening methods for altering circadian rhythm proteins |
| AU2004303826A1 (en) * | 2003-12-11 | 2005-07-07 | Aventis Pharmaceuticals Inc. | Substituted 1H-pyrrolo[3,2-b, 3,2-c, and 2,3-c]pyridine-2-carboxamides and related analogs as inhibitors of casein kinase I Epsilon |
-
2005
- 2005-07-18 JO JO2005104A patent/JO2629B1/en active
- 2005-08-09 SV SV2005002190A patent/SV2006002190A/es not_active Application Discontinuation
- 2005-08-09 GT GT200500215A patent/GT200500215A/es unknown
- 2005-08-16 AR ARP050103439A patent/AR051008A1/es unknown
- 2005-08-17 PE PE2005000956A patent/PE20060630A1/es not_active Application Discontinuation
- 2005-08-18 DE DE602005021889T patent/DE602005021889D1/de not_active Expired - Lifetime
- 2005-08-18 RU RU2007109812/04A patent/RU2403257C2/ru not_active IP Right Cessation
- 2005-08-18 PL PL05826812T patent/PL1784409T3/pl unknown
- 2005-08-18 EP EP05826812A patent/EP1784409B1/en not_active Expired - Lifetime
- 2005-08-18 MY MYPI20053879A patent/MY139831A/en unknown
- 2005-08-18 WO PCT/US2005/029383 patent/WO2006021000A2/en not_active Ceased
- 2005-08-18 JP JP2007528007A patent/JP4869232B2/ja not_active Expired - Fee Related
- 2005-08-18 BR BRPI0514419-1A patent/BRPI0514419A/pt not_active Application Discontinuation
- 2005-08-18 ES ES05826812T patent/ES2347166T3/es not_active Expired - Lifetime
- 2005-08-18 PT PT05826812T patent/PT1784409E/pt unknown
- 2005-08-18 AT AT05826812T patent/ATE471326T1/de active
- 2005-08-18 CN CNB2005800269958A patent/CN100562521C/zh not_active Expired - Fee Related
- 2005-08-18 AU AU2005272584A patent/AU2005272584B2/en not_active Ceased
- 2005-08-18 CA CA2577879A patent/CA2577879C/en not_active Expired - Fee Related
- 2005-08-18 KR KR1020077003865A patent/KR20070045263A/ko not_active Abandoned
- 2005-08-18 DK DK05826812.9T patent/DK1784409T3/da active
- 2005-08-18 RS RSP-2010/0401A patent/RS51413B/sr unknown
- 2005-08-18 HR HR20100475T patent/HRP20100475T1/hr unknown
- 2005-08-18 SI SI200531094T patent/SI1784409T1/sl unknown
- 2005-08-19 PA PA20058642801A patent/PA8642801A1/es unknown
- 2005-08-19 UY UY29077A patent/UY29077A1/es not_active Application Discontinuation
- 2005-08-19 TW TW094128282A patent/TWI372149B/zh not_active IP Right Cessation
-
2007
- 2007-02-04 IL IL181158A patent/IL181158A0/en unknown
- 2007-02-13 US US11/674,349 patent/US7393867B2/en not_active Expired - Lifetime
-
2008
- 2008-05-22 US US12/125,450 patent/US7652046B2/en not_active Expired - Lifetime
-
2010
- 2010-09-09 CY CY20101100823T patent/CY1110775T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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