ATE469982T1 - Bestimmung des genotyps eines amplifikationsproduktes an mehreren allelen stellen - Google Patents
Bestimmung des genotyps eines amplifikationsproduktes an mehreren allelen stellenInfo
- Publication number
- ATE469982T1 ATE469982T1 AT99903026T AT99903026T ATE469982T1 AT E469982 T1 ATE469982 T1 AT E469982T1 AT 99903026 T AT99903026 T AT 99903026T AT 99903026 T AT99903026 T AT 99903026T AT E469982 T1 ATE469982 T1 AT E469982T1
- Authority
- AT
- Austria
- Prior art keywords
- fluorescer
- fluorescence
- allelic
- target sequence
- sites
- Prior art date
Links
- 230000003321 amplification Effects 0.000 title abstract 4
- 238000003199 nucleic acid amplification method Methods 0.000 title abstract 4
- 108700028369 Alleles Proteins 0.000 title 1
- 238000002189 fluorescence spectrum Methods 0.000 abstract 3
- 101710163270 Nuclease Proteins 0.000 abstract 2
- 108020005187 Oligonucleotide Probes Proteins 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 239000002751 oligonucleotide probe Substances 0.000 abstract 2
- 239000000523 sample Substances 0.000 abstract 2
- 238000003205 genotyping method Methods 0.000 abstract 1
- 238000010791 quenching Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6858—Allele-specific amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Amplifiers (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1859598A | 1998-02-04 | 1998-02-04 | |
| PCT/US1999/000499 WO1999040226A2 (en) | 1998-02-04 | 1999-01-08 | Determination of a genotype of an amplification product at multiple allelic sites |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE469982T1 true ATE469982T1 (de) | 2010-06-15 |
Family
ID=21788757
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99903026T ATE469982T1 (de) | 1998-02-04 | 1999-01-08 | Bestimmung des genotyps eines amplifikationsproduktes an mehreren allelen stellen |
Country Status (8)
| Country | Link |
|---|---|
| US (5) | US6154707A (enExample) |
| EP (1) | EP1053348B1 (enExample) |
| JP (1) | JP4388694B2 (enExample) |
| AT (1) | ATE469982T1 (enExample) |
| AU (1) | AU758463B2 (enExample) |
| CA (1) | CA2318880C (enExample) |
| DE (1) | DE69942444D1 (enExample) |
| WO (1) | WO1999040226A2 (enExample) |
Families Citing this family (81)
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| CA2255599C (en) | 1996-04-25 | 2006-09-05 | Bioarray Solutions, Llc | Light-controlled electrokinetic assembly of particles near surfaces |
| AU1232099A (en) * | 1997-11-04 | 1999-05-24 | Roche Diagnostics Gmbh | Specific and sensitive method for detecting nucleic acids |
| CA2318880C (en) * | 1998-02-04 | 2010-07-27 | Perkin-Elmer Corporation | Determination of a genotype of an amplification product at multiple allelic sites |
| CA2387306C (en) * | 1999-10-22 | 2010-04-27 | The Public Health Research Institute Of The City Of New York, Inc. | Assays for short sequence variants |
| US7585632B2 (en) * | 1999-10-29 | 2009-09-08 | Hologic, Inc. | Compositions and methods for the detection of a nucleic acid using a cleavage reaction |
| US6660845B1 (en) | 1999-11-23 | 2003-12-09 | Epoch Biosciences, Inc. | Non-aggregating, non-quenching oligomers comprising nucleotide analogues; methods of synthesis and use thereof |
| US6727356B1 (en) | 1999-12-08 | 2004-04-27 | Epoch Pharmaceuticals, Inc. | Fluorescent quenching detection reagents and methods |
| US20040081959A9 (en) | 1999-12-08 | 2004-04-29 | Epoch Biosciences, Inc. | Fluorescent quenching detection reagents and methods |
| JP2001299392A (ja) * | 2000-04-25 | 2001-10-30 | Otsuka Pharmaceut Co Ltd | Catch22症候群検出方法 |
| US7435541B2 (en) | 2000-05-23 | 2008-10-14 | Sequenom, Inc. | Restriction enzyme genotyping |
| JP2004511210A (ja) * | 2000-05-23 | 2004-04-15 | バリアジェニックス インコーポレーテッド | 配列変動を検出する、dnaを遺伝分析するための方法 |
| ATE319087T1 (de) | 2000-06-21 | 2006-03-15 | Bioarray Solutions Ltd | Multianalytische molekularanalyse durch verwendung anwendungsspezifischer zufallspartikelarrays |
| US9709559B2 (en) | 2000-06-21 | 2017-07-18 | Bioarray Solutions, Ltd. | Multianalyte molecular analysis using application-specific random particle arrays |
| GB0016516D0 (en) * | 2000-07-06 | 2000-08-23 | Owen Mumford Ltd | Improvements relating to needle protection devices |
| US7267945B2 (en) * | 2001-03-26 | 2007-09-11 | Applera Corporation | Methods of determining the presence of polynucleotides employing amplification |
| US20030143554A1 (en) * | 2001-03-31 | 2003-07-31 | Berres Mark E. | Method of genotyping by determination of allele copy number |
| US7262063B2 (en) | 2001-06-21 | 2007-08-28 | Bio Array Solutions, Ltd. | Directed assembly of functional heterostructures |
| NZ530602A (en) * | 2001-06-28 | 2006-02-24 | Chiron Corp | Methods for detecting human parvovirus B19 in a biological sample comprising hybridising primers with a target sequence, the presence of which indicates the presence of the virus |
| JP4377689B2 (ja) | 2001-10-15 | 2009-12-02 | バイオアレイ ソリューションズ リミテッド | 同時尋問及び酵素仲介検出による多型遺伝子座の複合分析 |
| EP1439222A1 (en) * | 2001-10-26 | 2004-07-21 | Matsushita Electric Industrial Co., Ltd. | Method of detecting target nucleic acid and nucleic acid probe |
| US7732138B2 (en) * | 2001-11-07 | 2010-06-08 | Diagcor Bioscience Incorporation Limited | Rapid genotyping analysis and the device thereof |
| US20050079493A1 (en) * | 2002-11-09 | 2005-04-14 | Tam Joseph Wing On | DNA fingerprinting using allelic specific oligonucleotide reversed dot blot (ASO-RDB) flow through hybridization process and device |
| US20110111389A1 (en) | 2001-11-07 | 2011-05-12 | Diagcor Bioscience Incorporation Limited | Rapid genotyping analysis for human papillomavirus and the device thereof |
| AU2003216489A1 (en) * | 2002-03-05 | 2003-09-22 | M.C.W Research Foundation, Inc. | Methods and compositions for pharmacological and toxicological evaluation of test agents |
| US7176002B2 (en) * | 2002-05-16 | 2007-02-13 | Applera Corporation | Universal-tagged oligonucleotide primers and methods of use |
| US20070059690A1 (en) * | 2002-05-31 | 2007-03-15 | Amirul Islam | "Met/fret based method of target nucleic acid detection whereby the donor/acceptor moieties are on complementary strands" |
| AU2003240295A1 (en) * | 2002-06-20 | 2004-01-06 | Vision Biosystems Limited | Biological reaction apparatus with draining mechanism |
| AU2003901871A0 (en) * | 2003-03-31 | 2003-05-08 | Vision Biosystems Limited | A method and apparatus for fluid dispensation, preparation and dilation |
| US7252940B2 (en) * | 2002-08-21 | 2007-08-07 | Epoch Biosciences, Inc. | Abasic site endonuclease assay |
| WO2004047007A1 (en) | 2002-11-15 | 2004-06-03 | Bioarray Solutions, Ltd. | Analysis, secure access to, and transmission of array images |
| US20050066276A1 (en) * | 2002-12-13 | 2005-03-24 | Moore Helen M. | Methods for identifying, viewing, and analyzing syntenic and orthologous genomic regions between two or more species |
| US7851150B2 (en) * | 2002-12-18 | 2010-12-14 | Third Wave Technologies, Inc. | Detection of small nucleic acids |
| CN101405404A (zh) | 2002-12-31 | 2009-04-08 | 迈特默菲公司 | 用于推断牛的性状的组合物、方法和系统 |
| US7858301B2 (en) * | 2003-05-07 | 2010-12-28 | Bioarray Solutions, Ltd. | Method of probe design for nucleic acid analysis by multiplexed hybridization |
| ATE553216T1 (de) * | 2003-06-20 | 2012-04-15 | Exiqon As | Sonden, bibliotheken und kits zur analyse von nukleinsäuregemischen und verfahren zu deren konstruktion |
| US20050038776A1 (en) * | 2003-08-15 | 2005-02-17 | Ramin Cyrus | Information system for biological and life sciences research |
| WO2005029705A2 (en) | 2003-09-18 | 2005-03-31 | Bioarray Solutions, Ltd. | Number coding for identification of subtypes of coded types of solid phase carriers |
| US20050221357A1 (en) * | 2003-09-19 | 2005-10-06 | Mark Shannon | Normalization of gene expression data |
| US7417726B2 (en) * | 2003-09-19 | 2008-08-26 | Applied Biosystems Inc. | Normalization of data using controls |
| EP1664722B1 (en) | 2003-09-22 | 2011-11-02 | Bioarray Solutions Ltd | Surface immobilized polyelectrolyte with multiple functional groups capable of covalently bonding to biomolecules |
| US7332280B2 (en) * | 2003-10-14 | 2008-02-19 | Ronald Levy | Classification of patients having diffuse large B-cell lymphoma based upon gene expression |
| WO2005042763A2 (en) | 2003-10-28 | 2005-05-12 | Bioarray Solutions Ltd. | Optimization of gene expression analysis using immobilized capture probes |
| US7049077B2 (en) | 2003-10-29 | 2006-05-23 | Bioarray Solutions Ltd. | Multiplexed nucleic acid analysis by fragmentation of double-stranded DNA |
| WO2005049849A2 (en) | 2003-11-14 | 2005-06-02 | Integrated Dna Technologies, Inc. | Fluorescence quenching azo dyes, their methods of preparation and use |
| EP1561823A1 (de) * | 2004-02-04 | 2005-08-10 | Biotez Berlin-Buch GmbH | Verfahren zum Nachweis von Einzelnukleotid-polymorphismen (SNP) in Genen des Arzneimittelmetabolismus und Testkit zur Durchführung des Verfahrens |
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| US7575863B2 (en) * | 2004-05-28 | 2009-08-18 | Applied Biosystems, Llc | Methods, compositions, and kits comprising linker probes for quantifying polynucleotides |
| US7848889B2 (en) | 2004-08-02 | 2010-12-07 | Bioarray Solutions, Ltd. | Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification |
| US7642055B2 (en) * | 2004-09-21 | 2010-01-05 | Applied Biosystems, Llc | Two-color real-time/end-point quantitation of microRNAs (miRNAs) |
| US20060111915A1 (en) * | 2004-11-23 | 2006-05-25 | Applera Corporation | Hypothesis generation |
| US8084260B2 (en) * | 2004-11-24 | 2011-12-27 | Applied Biosystems, Llc | Spectral calibration method and system for multiple instruments |
| EP1829964A4 (en) * | 2004-12-08 | 2009-03-04 | Takeshi Yamamoto | METHOD OF STUDYING A SEQUENCE OF A GENE |
| US20060166238A1 (en) * | 2004-12-22 | 2006-07-27 | Ramsing Niels B | Probes, libraries and kits for analysis of mixtures of nucleic acids and methods for constructing the same |
| CA2601554A1 (en) | 2005-05-20 | 2006-11-30 | Integrated Dna Technologies, Inc. | Compounds and methods for labeling oligonucleotides |
| US8486629B2 (en) | 2005-06-01 | 2013-07-16 | Bioarray Solutions, Ltd. | Creation of functionalized microparticle libraries by oligonucleotide ligation or elongation |
| EP2477029A1 (en) | 2005-06-02 | 2012-07-18 | Fluidigm Corporation | Analysis using microfluidic partitioning devices |
| WO2007024800A2 (en) * | 2005-08-22 | 2007-03-01 | Applera Corporation | Device and method for making discrete volumes of a first fluid in contact with a second fluid, which are immiscible with each other |
| WO2007147074A2 (en) | 2006-06-14 | 2007-12-21 | Living Microsystems, Inc. | Use of highly parallel snp genotyping for fetal diagnosis |
| CN101675169B (zh) * | 2006-06-14 | 2018-01-02 | 维里纳塔健康公司 | 使用样品拆分和dna标签进行稀有细胞分析 |
| WO2008111990A1 (en) * | 2006-06-14 | 2008-09-18 | Cellpoint Diagnostics, Inc. | Rare cell analysis using sample splitting and dna tags |
| EP2589668A1 (en) | 2006-06-14 | 2013-05-08 | Verinata Health, Inc | Rare cell analysis using sample splitting and DNA tags |
| US20080050739A1 (en) | 2006-06-14 | 2008-02-28 | Roland Stoughton | Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats |
| US8137912B2 (en) | 2006-06-14 | 2012-03-20 | The General Hospital Corporation | Methods for the diagnosis of fetal abnormalities |
| EP1911852B1 (en) * | 2006-10-12 | 2009-07-29 | Bio-Rad Pasteur | Double-stranded probes for the fluorescent detection of nucleic acids |
| DE102007013099A1 (de) | 2007-03-14 | 2008-09-18 | Aj Innuscreen Gmbh | Verfahren und Testkit zum schnellen Nachweis spezifischer Nukleinsäuresequenzen, insbesondere zum Nachweis von Mutationen oder SNP's |
| EP2336358A1 (en) * | 2008-05-06 | 2011-06-22 | QIAGEN GmbH | Simultaneous detection of multiple nucleic acid sequences in a reaction |
| CA2726850C (en) * | 2008-06-13 | 2015-06-02 | Codexis, Inc. | Method of synthesizing polynucleotide variants |
| US20090312196A1 (en) * | 2008-06-13 | 2009-12-17 | Codexis, Inc. | Method of synthesizing polynucleotide variants |
| US8383346B2 (en) * | 2008-06-13 | 2013-02-26 | Codexis, Inc. | Combined automated parallel synthesis of polynucleotide variants |
| CA2737643C (en) | 2008-09-20 | 2020-10-06 | Hei-Mun Fan | Noninvasive diagnosis of fetal aneuploidy by sequencing |
| WO2010120800A1 (en) * | 2009-04-13 | 2010-10-21 | Canon U.S. Life Sciences, Inc. | A rapid method of pattern recognition, machine learning, and automated genotype classification through correlation analysis of dynamic signals |
| US20110312503A1 (en) | 2010-01-23 | 2011-12-22 | Artemis Health, Inc. | Methods of fetal abnormality detection |
| US8916345B2 (en) | 2010-03-26 | 2014-12-23 | Integrated Dna Technologies, Inc. | Methods for enhancing nucleic acid hybridization |
| US9506057B2 (en) | 2010-03-26 | 2016-11-29 | Integrated Dna Technologies, Inc. | Modifications for antisense compounds |
| EP2896696B1 (en) | 2010-09-07 | 2017-12-27 | Integrated Dna Technologies, Inc. | Modifications for antisense compounds |
| US20120083035A1 (en) | 2010-09-30 | 2012-04-05 | Dharmacon, Inc. | Modified Cell Lines for Increasing Lentiviral Titers |
| US9617588B2 (en) | 2010-10-05 | 2017-04-11 | Thermo Fisher Scientific Baltics Uab | Enzyme mixture |
| CA2874343C (en) | 2012-05-21 | 2021-11-09 | Fluidigm Corporation | Single-particle analysis of particle populations |
| US20170292144A1 (en) * | 2016-04-06 | 2017-10-12 | Life Technologies Corporation | Compositions, methods, and kits for synthesis and detection of nucleic acids |
| JP6846636B2 (ja) * | 2017-02-28 | 2021-03-24 | パナソニックIpマネジメント株式会社 | 核酸検出用オリゴヌクレオチド |
| WO2022155397A1 (en) * | 2021-01-15 | 2022-07-21 | Nuprobe Usa, Inc. | Cycle multiplexing for highly multiplexed quantitative pcr |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5075216A (en) * | 1988-09-23 | 1991-12-24 | Cetus Corporation | Methods for dna sequencing with thermus aquaticus dna polymerase |
| JP3392863B2 (ja) * | 1990-07-24 | 2003-03-31 | エフ.ホフマン ― ラ ロシュ アーゲー | 修飾核酸塩基を使用するインビトロ核酸増幅における非特異的増幅の低減 |
| US5210015A (en) * | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
| US5403707A (en) * | 1993-05-14 | 1995-04-04 | Eastman Kodak Company | Diagnostic compositions, elements, methods and test kits for amplification and detection of retroviral DNA using primers having matched melting temperatures |
| US5538848A (en) * | 1994-11-16 | 1996-07-23 | Applied Biosystems Division, Perkin-Elmer Corp. | Method for detecting nucleic acid amplification using self-quenching fluorescence probe |
| US5834181A (en) * | 1994-07-28 | 1998-11-10 | Genzyme Corporation | High throughput screening method for sequences or genetic alterations in nucleic acids |
| CA2209080C (en) * | 1994-12-30 | 2008-07-29 | Georgetown University | Fluorometric assay for detecting nucleic acid cleavage |
| DE19524579C2 (de) * | 1995-07-06 | 1997-12-18 | Daimler Benz Ag | Transformator als Strombegrenzer |
| US5792610A (en) * | 1996-05-01 | 1998-08-11 | Biorad Laboratories, Inc. | Method for conducting multiparametric fluorescence in situ hybridization |
| US5759781A (en) * | 1995-12-22 | 1998-06-02 | Yale University | Multiparametric fluorescence in situ hybridization |
| CA2252048C (en) * | 1996-04-12 | 2008-03-11 | The Public Health Research Institute Of The City Of New York, Inc. | Detection probes, kits and assays |
| US6015667A (en) * | 1996-06-03 | 2000-01-18 | The Perkin-Emer Corporation | Multicomponent analysis method including the determination of a statistical confidence interval |
| US5736333A (en) * | 1996-06-04 | 1998-04-07 | The Perkin-Elmer Corporation | Passive internal references for the detection of nucleic acid amplification products |
| CA2318880C (en) | 1998-02-04 | 2010-07-27 | Perkin-Elmer Corporation | Determination of a genotype of an amplification product at multiple allelic sites |
| US5952202A (en) * | 1998-03-26 | 1999-09-14 | The Perkin Elmer Corporation | Methods using exogenous, internal controls and analogue blocks during nucleic acid amplification |
-
1999
- 1999-01-08 CA CA2318880A patent/CA2318880C/en not_active Expired - Fee Related
- 1999-01-08 WO PCT/US1999/000499 patent/WO1999040226A2/en not_active Ceased
- 1999-01-08 EP EP99903026A patent/EP1053348B1/en not_active Expired - Lifetime
- 1999-01-08 AT AT99903026T patent/ATE469982T1/de not_active IP Right Cessation
- 1999-01-08 AU AU23144/99A patent/AU758463B2/en not_active Ceased
- 1999-01-08 JP JP2000530635A patent/JP4388694B2/ja not_active Expired - Lifetime
- 1999-01-08 DE DE69942444T patent/DE69942444D1/de not_active Expired - Lifetime
- 1999-06-03 US US09/324,709 patent/US6154707A/en not_active Expired - Lifetime
-
2002
- 2002-03-21 US US10/104,774 patent/US6884583B2/en not_active Expired - Lifetime
-
2003
- 2003-06-04 US US10/455,150 patent/US7132239B2/en not_active Expired - Fee Related
-
2006
- 2006-11-03 US US11/592,716 patent/US20080187913A1/en not_active Abandoned
-
2009
- 2009-11-13 US US12/618,686 patent/US20120053069A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1053348B1 (en) | 2010-06-02 |
| DE69942444D1 (de) | 2010-07-15 |
| US7132239B2 (en) | 2006-11-07 |
| AU2314499A (en) | 1999-08-23 |
| EP1053348A2 (en) | 2000-11-22 |
| WO1999040226A2 (en) | 1999-08-12 |
| CA2318880A1 (en) | 1999-08-12 |
| CA2318880C (en) | 2010-07-27 |
| US20120053069A1 (en) | 2012-03-01 |
| WO1999040226A3 (en) | 2000-08-17 |
| US6154707A (en) | 2000-11-28 |
| JP2002502615A (ja) | 2002-01-29 |
| US20080187913A1 (en) | 2008-08-07 |
| US6884583B2 (en) | 2005-04-26 |
| JP4388694B2 (ja) | 2009-12-24 |
| AU758463B2 (en) | 2003-03-20 |
| US20040053302A1 (en) | 2004-03-18 |
| US20020164630A1 (en) | 2002-11-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |