ATE468394T1 - Vermischen von heterologen dns-sequenzen - Google Patents

Vermischen von heterologen dns-sequenzen

Info

Publication number
ATE468394T1
ATE468394T1 AT98907912T AT98907912T ATE468394T1 AT E468394 T1 ATE468394 T1 AT E468394T1 AT 98907912 T AT98907912 T AT 98907912T AT 98907912 T AT98907912 T AT 98907912T AT E468394 T1 ATE468394 T1 AT E468394T1
Authority
AT
Austria
Prior art keywords
conserved region
fragments
shuffling
interest
identification
Prior art date
Application number
AT98907912T
Other languages
German (de)
English (en)
Inventor
Torben Borchert
Titus Kretzschmar
Joel Cherry
Original Assignee
Novozymes As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26063733&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE468394(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novozymes As filed Critical Novozymes As
Application granted granted Critical
Publication of ATE468394T1 publication Critical patent/ATE468394T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • C12N15/1027—Mutagenizing nucleic acids by DNA shuffling, e.g. RSR, STEP, RPR

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT98907912T 1997-03-18 1998-03-18 Vermischen von heterologen dns-sequenzen ATE468394T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK30497 1997-03-18
DK43297 1997-04-17
PCT/DK1998/000105 WO1998041623A1 (en) 1997-03-18 1998-03-18 Shuffling of heterologous dna sequences

Publications (1)

Publication Number Publication Date
ATE468394T1 true ATE468394T1 (de) 2010-06-15

Family

ID=26063733

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98907912T ATE468394T1 (de) 1997-03-18 1998-03-18 Vermischen von heterologen dns-sequenzen

Country Status (10)

Country Link
EP (1) EP1015575B1 (enExample)
JP (1) JP2001516216A (enExample)
AT (1) ATE468394T1 (enExample)
AU (1) AU738461B2 (enExample)
CA (1) CA2284097A1 (enExample)
DE (1) DE69841674D1 (enExample)
DK (1) DK1015575T3 (enExample)
IL (1) IL131986A0 (enExample)
NZ (1) NZ337910A (enExample)
WO (1) WO1998041623A1 (enExample)

Families Citing this family (60)

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US6117679A (en) * 1994-02-17 2000-09-12 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US6995017B1 (en) 1994-02-17 2006-02-07 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US6335160B1 (en) 1995-02-17 2002-01-01 Maxygen, Inc. Methods and compositions for polypeptide engineering
US6309883B1 (en) 1994-02-17 2001-10-30 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
US20060257890A1 (en) 1996-05-20 2006-11-16 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
US6936289B2 (en) 1995-06-07 2005-08-30 Danisco A/S Method of improving the properties of a flour dough, a flour dough improving composition and improved food products
US7148054B2 (en) 1997-01-17 2006-12-12 Maxygen, Inc. Evolution of whole cells and organisms by recursive sequence recombination
US6326204B1 (en) 1997-01-17 2001-12-04 Maxygen, Inc. Evolution of whole cells and organisms by recursive sequence recombination
US6153410A (en) * 1997-03-25 2000-11-28 California Institute Of Technology Recombination of polynucleotide sequences using random or defined primers
DE1193314T1 (de) 1997-04-09 2002-10-02 Danisco A/S, Copenhagen Lipase und Verwendung davon zur Verbesserung von Teigen und Backwaren
JP3712255B2 (ja) 1997-12-08 2005-11-02 カリフォルニア・インスティチュート・オブ・テクノロジー ポリヌクレオチドおよびポリペプチド配列を生成するための方法
US7390619B1 (en) 1998-02-11 2008-06-24 Maxygen, Inc. Optimization of immunomodulatory properties of genetic vaccines
WO1999057128A1 (en) 1998-05-01 1999-11-11 Maxygen, Inc. Optimization of pest resistance genes using dna shuffling
US7153655B2 (en) 1998-06-16 2006-12-26 Alligator Bioscience Ab Method for in vitro molecular evolution of protein function involving the use of exonuclease enzyme and two populations of parent polynucleotide sequence
US6846655B1 (en) 1998-06-29 2005-01-25 Phylos, Inc. Methods for generating highly diverse libraries
EP1104459A1 (en) 1998-08-12 2001-06-06 Maxygen, Inc. Dna shuffling of monooxygenase genes for production of industrial chemicals
WO2000020573A2 (en) 1998-10-07 2000-04-13 Maxygen, Inc. Dna shuffling to produce nucleic acids for mycotoxin detoxification
WO2000028018A1 (en) 1998-11-10 2000-05-18 Maxygen, Inc. Modified adp-glucose pyrophosphorylase for improvement and optimization of plant phenotypes
US6436675B1 (en) 1999-09-28 2002-08-20 Maxygen, Inc. Use of codon-varied oligonucleotide synthesis for synthetic shuffling
US6917882B2 (en) 1999-01-19 2005-07-12 Maxygen, Inc. Methods for making character strings, polynucleotides and polypeptides having desired characteristics
US6376246B1 (en) 1999-02-05 2002-04-23 Maxygen, Inc. Oligonucleotide mediated nucleic acid recombination
JP2002534966A (ja) 1999-01-19 2002-10-22 マキシジェン， インコーポレイテッド オリゴヌクレオチド媒介核酸組換え
US7024312B1 (en) 1999-01-19 2006-04-04 Maxygen, Inc. Methods for making character strings, polynucleotides and polypeptides having desired characteristics
US6961664B2 (en) 1999-01-19 2005-11-01 Maxygen Methods of populating data structures for use in evolutionary simulations
JP2003524394A (ja) 1999-02-11 2003-08-19 マキシジェン， インコーポレイテッド ハイスループット質量分析法
US6531316B1 (en) 1999-03-05 2003-03-11 Maxyag, Inc. Encryption of traits using split gene sequences and engineered genetic elements
AU4456200A (en) * 1999-04-13 2000-11-14 Maxygen, Inc. Modified starch metabolism enzymes and encoding genes for improvement and optimization of plant phenotypes
US7430477B2 (en) 1999-10-12 2008-09-30 Maxygen, Inc. Methods of populating data structures for use in evolutionary simulations
US6686515B1 (en) 1999-11-23 2004-02-03 Maxygen, Inc. Homologous recombination in plants
US7115712B1 (en) 1999-12-02 2006-10-03 Maxygen, Inc. Cytokine polypeptides
EP1276900A2 (en) 2000-01-11 2003-01-22 Maxygen, Inc. Integrated systems and methods for diversity generation and screening
US6248541B1 (en) 2000-04-21 2001-06-19 Genencor International, Inc. Screening under nutrient limited conditions
US6534292B1 (en) 2000-05-08 2003-03-18 Genencor International, Inc. Methods for forming recombined nucleic acids
CA2405520A1 (en) * 2000-05-23 2001-11-29 California Institute Of Technology Gene recombination and hybrid protein development
JP2004513878A (ja) 2000-06-23 2004-05-13 マキシジェン，　インコーポレイテッド 新規同時刺激分子
EP1297146A2 (en) 2000-06-23 2003-04-02 Maxygen, Inc. Novel chimeric promoters
WO2002000852A2 (en) 2000-06-26 2002-01-03 Novozymes A/S Lipolytic enzyme
US6994963B1 (en) 2000-07-10 2006-02-07 Ambion, Inc. Methods for recombinatorial nucleic acid synthesis
US6858422B2 (en) 2000-07-13 2005-02-22 Codexis, Inc. Lipase genes
AUPQ974900A0 (en) * 2000-08-29 2000-09-21 Macquarie Research Limited Degenerate oligonucleotide gene-shuffling
US6582914B1 (en) 2000-10-26 2003-06-24 Genencor International, Inc. Method for generating a library of oligonucleotides comprising a controlled distribution of mutations
US6958213B2 (en) 2000-12-12 2005-10-25 Alligator Bioscience Ab Method for in vitro molecular evolution of protein function
NZ528260A (en) 2001-05-18 2005-09-30 Danisco Method of improving dough and bread quality with the addition of an enzyme that hydrolyses a glycolipid and a phospholipid and incapable of hydrolysing a triglyceride or monoglyceride
DK2295544T3 (en) 2001-06-26 2016-09-26 Novozymes As Polypeptides with cellobiohydrolase I activity and the same coding polynucleotides
DE60202478T3 (de) 2001-07-23 2010-01-07 Dsm Ip Assets B.V. Verfahren zur herstellung von polynukleotidvarianten
US7262012B2 (en) 2002-05-17 2007-08-28 Alligator Bioscience Ab Method for in vitro molecular evolution of protein function using varied exonuclease digestion in two polynucleotide populations
CN101555472A (zh) 2002-12-20 2009-10-14 诺维信公司 具有纤维二糖水解酶ⅱ活性的多肽及编码它的多核苷酸
EP1578963B1 (en) 2002-12-20 2015-02-25 Novozymes A/S Galactanase variants
MXPA05007654A (es) 2003-01-17 2005-09-30 Danisco Metodo.
EP2228440B1 (en) 2003-05-02 2012-08-22 Novozymes Inc. Variants of beta-glucosidases
WO2005030926A2 (en) 2003-08-25 2005-04-07 Novozymes Inc. Variants of glycoside hydrolases
JP2007509603A (ja) 2003-10-10 2007-04-19 ノボザイムス アクティーゼルスカブ プロテアーゼ変異型
AU2005215852B2 (en) 2004-02-25 2010-04-22 Novozymes A/S Fungal cell wall degrading enzyme
GB0405637D0 (en) 2004-03-12 2004-04-21 Danisco Protein
US9045748B2 (en) 2004-05-27 2015-06-02 Novozymes, Inc. Methods for transforming and expression screening of filamentous fungal cells with a DNA library
AU2005264077B2 (en) 2004-07-16 2011-06-02 Dupont Nutrition Biosciences Aps Lipolytic enzyme uses thereof in the food industry
WO2016164583A2 (en) 2015-04-07 2016-10-13 Novozymes A/S Methods for selecting enzymes having enhanced activity
EP3280818A2 (en) 2015-04-07 2018-02-14 Novozymes A/S Methods for selecting enzymes having lipase activity
CN109312333A (zh) 2016-04-07 2019-02-05 诺维信公司 选择具有蛋白酶活性的酶的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination

Also Published As

Publication number Publication date
EP1015575B1 (en) 2010-05-19
DK1015575T3 (da) 2010-08-23
WO1998041623A1 (en) 1998-09-24
DE69841674D1 (de) 2010-07-01
AU6611698A (en) 1998-10-12
CA2284097A1 (en) 1998-09-24
NZ337910A (en) 2001-10-26
AU738461B2 (en) 2001-09-20
JP2001516216A (ja) 2001-09-25
IL131986A0 (en) 2001-03-19
EP1015575A1 (en) 2000-07-05

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