ATE466853T1 - Cgrp-rezeptorantagonisten - Google Patents

Cgrp-rezeptorantagonisten

Info

Publication number
ATE466853T1
ATE466853T1 AT06718339T AT06718339T ATE466853T1 AT E466853 T1 ATE466853 T1 AT E466853T1 AT 06718339 T AT06718339 T AT 06718339T AT 06718339 T AT06718339 T AT 06718339T AT E466853 T1 ATE466853 T1 AT E466853T1
Authority
AT
Austria
Prior art keywords
receptor antagonists
cgrp receptor
cgrp
compounds
diseases
Prior art date
Application number
AT06718339T
Other languages
English (en)
Inventor
Christopher Burgey
Theresa WILLIAMS
Zhengwu Deng
Craig Stump
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Application granted granted Critical
Publication of ATE466853T1 publication Critical patent/ATE466853T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT06718339T 2005-01-18 2006-01-13 Cgrp-rezeptorantagonisten ATE466853T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64465005P 2005-01-18 2005-01-18
PCT/US2006/001252 WO2006078554A2 (en) 2005-01-18 2006-01-13 Cgrp receptor antagonists

Publications (1)

Publication Number Publication Date
ATE466853T1 true ATE466853T1 (de) 2010-05-15

Family

ID=36692743

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06718339T ATE466853T1 (de) 2005-01-18 2006-01-13 Cgrp-rezeptorantagonisten

Country Status (9)

Country Link
US (1) US7632832B2 (de)
EP (1) EP1856100B1 (de)
JP (1) JP2008526984A (de)
CN (1) CN101103020B (de)
AT (1) ATE466853T1 (de)
AU (1) AU2006206718B2 (de)
CA (1) CA2594940A1 (de)
DE (1) DE602006014097D1 (de)
WO (1) WO2006078554A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008515895A (ja) * 2004-10-07 2008-05-15 メルク エンド カムパニー インコーポレーテッド Cgrp受容体拮抗薬
EP2013213B1 (de) 2006-05-02 2011-07-27 Bristol-Myers Squibb Company Verbindungen mit eingeschränkter konformation als cgrp rezeptor antagonisten.
US7470680B2 (en) 2006-05-03 2008-12-30 Bristol-Myers Squibb Company Constrained compounds as CGRP-receptor antagonists
EP2029575B1 (de) * 2006-05-09 2014-10-22 Merck Sharp & Dohme Corp. Substituierte spirocyclische antagonisten des cgrp-rezeptors
KR20170091770A (ko) 2006-07-10 2017-08-09 파이온 유케이 리미티드 속효형 벤조디아제핀 염 및 이의 중합체 형태
EP2305647A1 (de) * 2009-09-18 2011-04-06 PAION UK Limited Verfahren zur Herstellung von 3-[(4S)-8-brom-1-methyl-6-(2-pyridinyl)-4 H-imidazo[1,2-a][1,4]benzodiazepin-4-yl]propionsäuremethylester oder das Benzensulfonatsalz davon und in diesem Prozess nützliche Verbindungen
EP2450039A1 (de) 2010-11-08 2012-05-09 PAION UK Ltd. Dosierschema zur Sedierung mit CNS 7056 (Remimazolam)
RU2670272C2 (ru) * 2012-04-18 2018-10-22 Контера Фарма Апс Пероральная фармацевтическая композиция, подходящая для повышения эффективности лечения двигательных нарушений
AR094963A1 (es) 2013-03-04 2015-09-09 Ono Pharmaceutical Co Reacción de oxidación excelente en el índice de conversión
KR102443161B1 (ko) 2016-07-11 2022-09-14 콘테라 파르마 에이/에스 아침 운동 불능을 치료하기 위한 박동성 약물 전달 시스템
EP3366286A1 (de) 2017-02-22 2018-08-29 Johannes Keller Verbindungen zur behandlung von sepsis

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2345357A1 (en) 1998-09-30 2000-04-06 Merck Sharp & Dohme Limited Benzimidazolinyl piperidines as cgrp ligands
ATE466860T1 (de) 2003-04-15 2010-05-15 Merck Sharp & Dohme Cgrp-rezeptorantagonisten
AU2004252150B2 (en) * 2003-06-26 2008-11-20 Merck Sharp & Dohme Corp. Benzodiazepine CGRP receptor antagonists

Also Published As

Publication number Publication date
US20080125413A1 (en) 2008-05-29
CN101103020A (zh) 2008-01-09
CA2594940A1 (en) 2006-07-27
WO2006078554A3 (en) 2007-04-05
EP1856100B1 (de) 2010-05-05
EP1856100A4 (de) 2009-04-15
CN101103020B (zh) 2011-04-27
DE602006014097D1 (de) 2010-06-17
EP1856100A2 (de) 2007-11-21
WO2006078554A2 (en) 2006-07-27
JP2008526984A (ja) 2008-07-24
AU2006206718A1 (en) 2006-07-27
AU2006206718B2 (en) 2011-06-02
US7632832B2 (en) 2009-12-15

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties