ATE463562T1 - Lp-pla2-aktivitätstest mit hohem durchsatz - Google Patents
Lp-pla2-aktivitätstest mit hohem durchsatzInfo
- Publication number
- ATE463562T1 ATE463562T1 AT04753533T AT04753533T ATE463562T1 AT E463562 T1 ATE463562 T1 AT E463562T1 AT 04753533 T AT04753533 T AT 04753533T AT 04753533 T AT04753533 T AT 04753533T AT E463562 T1 ATE463562 T1 AT E463562T1
- Authority
- AT
- Austria
- Prior art keywords
- throughput
- activity assessment
- pla2 activity
- pla2
- assessment
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
- C12N9/20—Triglyceride splitting, e.g. by means of lipase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/44—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/916—Hydrolases (3) acting on ester bonds (3.1), e.g. phosphatases (3.1.3), phospholipases C or phospholipases D (3.1.4)
- G01N2333/918—Carboxylic ester hydrolases (3.1.1)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Biophysics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pyrane Compounds (AREA)
- Color Electrophotography (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47377703P | 2003-05-28 | 2003-05-28 | |
| PCT/US2004/016716 WO2005001416A2 (en) | 2003-05-28 | 2004-05-27 | High throughput assay of lp-pla2 activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE463562T1 true ATE463562T1 (de) | 2010-04-15 |
Family
ID=33551459
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04753533T ATE463562T1 (de) | 2003-05-28 | 2004-05-27 | Lp-pla2-aktivitätstest mit hohem durchsatz |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7531316B2 (de) |
| EP (2) | EP2253702A1 (de) |
| JP (2) | JP4892350B2 (de) |
| AT (1) | ATE463562T1 (de) |
| CY (1) | CY1110138T1 (de) |
| DE (1) | DE602004026439D1 (de) |
| DK (1) | DK1633864T3 (de) |
| ES (1) | ES2341772T3 (de) |
| HR (1) | HRP20100285T1 (de) |
| PL (1) | PL1633864T3 (de) |
| PT (1) | PT1633864E (de) |
| SI (1) | SI1633864T1 (de) |
| WO (1) | WO2005001416A2 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4892350B2 (ja) | 2003-05-28 | 2012-03-07 | グラクソ グループ リミテッド | Ｌｐ−ＰＬＡ２活性のハイスループットアッセイ |
| JP5155564B2 (ja) | 2004-02-03 | 2013-03-06 | ディアデクサス インコーポレーテッド | Ｌｐ−ＰＬＡ２活性を検出する方法 |
| US20150017671A1 (en) | 2004-04-16 | 2015-01-15 | Yaping Shou | Methods for detecting lp-pla2 activity and inhibition of lp-pla2 activity |
| US7741020B2 (en) | 2004-04-16 | 2010-06-22 | Glaxo Group Limited | Methods for detecting Lp-PLA2 activity and inhibition of Lp-PLA2 activity |
| US20140283157A1 (en) | 2013-03-15 | 2014-09-18 | Diadexus, Inc. | Lipoprotein-associated phospholipase a2 antibody compositions and methods of use |
| EP3258269B1 (de) * | 2015-02-10 | 2019-06-05 | Shenzhen New Industries Biomedical Engineering Co. Ltd. | Reagenzienkit für den nachweis von lipoproteinassoziierter phospholipase a2 und herstellungsverfahren sowie anwendung für reagenzienkit |
| CN104820097A (zh) * | 2015-05-22 | 2015-08-05 | 北京协和洛克生物技术有限责任公司 | 一种定量检测样本中脂蛋白磷脂酶a2浓度的液态芯片试剂盒及其制备方法 |
| JP6691212B2 (ja) | 2016-06-22 | 2020-04-28 | 旭化成ファーマ株式会社 | Ｌｐ−ＰＬＡ２活性の測定 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3204681B2 (ja) | 1991-05-24 | 2001-09-04 | 株式会社シノテスト | 新規なエーテル型チオリン脂質化合物およびその製造法 |
| DE69423436T2 (de) * | 1993-06-25 | 2000-09-07 | Smithkline Beecham Plc | An lipoprotein gebundene phospholipase a2, inhibitoren davon und deren verwendung für diagnose und therapie |
| JPH0759597A (ja) | 1993-08-23 | 1995-03-07 | Shinotesuto:Kk | 血小板活性化因子アセチルヒドロラーゼ活性測定方法 |
| US6146625A (en) | 1993-10-06 | 2000-11-14 | Icos Corporation | Platelet-activating factor acetylhydrolase |
| ES2159573T3 (es) | 1993-10-06 | 2001-10-16 | Icos Corp | Acetilhidrolasa del factor activador de plaquetas. |
| JPH1017600A (ja) | 1996-06-28 | 1998-01-20 | Suntory Ltd | 血小板活性化因子アセチルヒドロラーゼおよびその遺伝子 |
| JP4220603B2 (ja) | 1998-12-02 | 2009-02-04 | アルフレッサファーマ株式会社 | 血小板活性化因子アセチルヒドロラーゼ活性の測定方法 |
| US20020102231A1 (en) | 1999-05-07 | 2002-08-01 | Icos Corporation | Therapeutic uses of PAF-AH products in diabetes |
| FR2815857B1 (fr) | 2000-10-30 | 2003-02-14 | Oreal | Composition, notamment cosmetique, renfermant un retinoide et une silicone benzotriazole |
| EP1318154B1 (de) | 2001-12-07 | 2004-06-16 | SIRS-Lab GmbH | Verbindungen zur Bestimmung der Aktivität von Phospholipase A2 |
| US20030134082A1 (en) * | 2001-12-21 | 2003-07-17 | Morin Brian G. | Carpet comprising a low-shrink backing of polypropylene tape fibers |
| US20070077614A1 (en) | 2003-04-01 | 2007-04-05 | Wolfert Robert L | Uses of lp-pla2 in combination to assess coronary risk |
| JP4892350B2 (ja) | 2003-05-28 | 2012-03-07 | グラクソ グループ リミテッド | Ｌｐ−ＰＬＡ２活性のハイスループットアッセイ |
| JP5155564B2 (ja) | 2004-02-03 | 2013-03-06 | ディアデクサス インコーポレーテッド | Ｌｐ−ＰＬＡ２活性を検出する方法 |
| US7741020B2 (en) | 2004-04-16 | 2010-06-22 | Glaxo Group Limited | Methods for detecting Lp-PLA2 activity and inhibition of Lp-PLA2 activity |
-
2004
- 2004-05-27 JP JP2006533451A patent/JP4892350B2/ja not_active Expired - Fee Related
- 2004-05-27 DE DE602004026439T patent/DE602004026439D1/de not_active Expired - Lifetime
- 2004-05-27 ES ES04753533T patent/ES2341772T3/es not_active Expired - Lifetime
- 2004-05-27 PL PL04753533T patent/PL1633864T3/pl unknown
- 2004-05-27 PT PT04753533T patent/PT1633864E/pt unknown
- 2004-05-27 EP EP10158845A patent/EP2253702A1/de not_active Withdrawn
- 2004-05-27 DK DK04753533.1T patent/DK1633864T3/da active
- 2004-05-27 US US10/557,540 patent/US7531316B2/en not_active Expired - Fee Related
- 2004-05-27 AT AT04753533T patent/ATE463562T1/de active
- 2004-05-27 EP EP04753533A patent/EP1633864B1/de not_active Expired - Lifetime
- 2004-05-27 WO PCT/US2004/016716 patent/WO2005001416A2/en active Application Filing
- 2004-05-27 SI SI200431433T patent/SI1633864T1/sl unknown
-
2010
- 2010-05-21 HR HR20100285T patent/HRP20100285T1/hr unknown
- 2010-06-21 CY CY20101100572T patent/CY1110138T1/el unknown
-
2011
- 2011-09-22 JP JP2011207479A patent/JP5637959B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE602004026439D1 (de) | 2010-05-20 |
| ES2341772T3 (es) | 2010-06-28 |
| JP2012050443A (ja) | 2012-03-15 |
| WO2005001416A3 (en) | 2005-03-17 |
| PT1633864E (pt) | 2010-06-24 |
| JP5637959B2 (ja) | 2014-12-10 |
| EP2253702A1 (de) | 2010-11-24 |
| PL1633864T3 (pl) | 2010-09-30 |
| EP1633864B1 (de) | 2010-04-07 |
| DK1633864T3 (da) | 2010-07-12 |
| JP2007502131A (ja) | 2007-02-08 |
| CY1110138T1 (el) | 2015-01-14 |
| EP1633864A2 (de) | 2006-03-15 |
| HRP20100285T1 (hr) | 2010-06-30 |
| JP4892350B2 (ja) | 2012-03-07 |
| WO2005001416A2 (en) | 2005-01-06 |
| SI1633864T1 (sl) | 2010-07-30 |
| EP1633864A4 (de) | 2006-06-14 |
| US7531316B2 (en) | 2009-05-12 |
| US20070065892A1 (en) | 2007-03-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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