ATE459701T1 - Bioreaktor für die zell- und gewebekultur - Google Patents

Bioreaktor für die zell- und gewebekultur

Info

Publication number
ATE459701T1
ATE459701T1 AT06828762T AT06828762T ATE459701T1 AT E459701 T1 ATE459701 T1 AT E459701T1 AT 06828762 T AT06828762 T AT 06828762T AT 06828762 T AT06828762 T AT 06828762T AT E459701 T1 ATE459701 T1 AT E459701T1
Authority
AT
Austria
Prior art keywords
bioreactor
tissue
incubation
cell
volume
Prior art date
Application number
AT06828762T
Other languages
English (en)
Inventor
Peter Mose Larsen
Stephen John Fey
Original Assignee
Drugmode Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Drugmode Aps filed Critical Drugmode Aps
Application granted granted Critical
Publication of ATE459701T1 publication Critical patent/ATE459701T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/02Form or structure of the vessel
    • C12M23/16Microfluidic devices; Capillary tubes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/10Rotating vessel
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04Filters; Permeable or porous membranes or plates, e.g. dialysis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/067Hepatocytes
    • C12N5/0671Three-dimensional culture, tissue culture or organ culture; Encapsulated cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809Methods for determination or identification of nucleic acids involving differential detection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Sustainable Development (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT06828762T 2005-12-30 2006-12-22 Bioreaktor für die zell- und gewebekultur ATE459701T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200501852 2005-12-30
US83694306P 2006-08-11 2006-08-11
PCT/DK2006/000740 WO2007076865A1 (en) 2005-12-30 2006-12-22 Bioreactor for cell and tissue culture

Publications (1)

Publication Number Publication Date
ATE459701T1 true ATE459701T1 (de) 2010-03-15

Family

ID=37836613

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06828762T ATE459701T1 (de) 2005-12-30 2006-12-22 Bioreaktor für die zell- und gewebekultur

Country Status (7)

Country Link
US (1) US20100120136A1 (de)
EP (1) EP1966367B1 (de)
JP (1) JP5042235B2 (de)
AT (1) ATE459701T1 (de)
DE (1) DE602006012734D1 (de)
DK (1) DK1966367T3 (de)
WO (1) WO2007076865A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2857525T (pt) * 2008-02-29 2019-08-05 Univ Oxford Innovation Ltd Método de determinar uma dosagem adequada de estatina
US9817001B2 (en) 2008-05-27 2017-11-14 Boston Heart Diagnostics Corporation Methods for determining LDL cholesterol treatment
BRPI0802399B1 (pt) * 2008-07-08 2018-06-12 União Brasileira De Educação E Assistência- Mantenedora Da Pucrs Equipamento para incubação de peixes e outros animais e processo de cultivo de peixes e outros animais
US8470541B1 (en) * 2008-09-27 2013-06-25 Boston Heart Diagnostics Corporation Methods for separation and immuno-detection of biomolecules, and apparatus related thereto
US8778669B2 (en) 2009-07-22 2014-07-15 Corning Incorporated Multilayer tissue culture vessel
DK2606116T3 (da) * 2010-08-18 2020-08-03 Drugmode Aps Bioreaktorsystem
WO2012079577A1 (en) 2010-12-15 2012-06-21 Drugmode Aps Bioreactor with lid for easy access to incubation cavity
US9428724B2 (en) 2011-02-24 2016-08-30 Ge Healthcare Bio-Sciences Ab Bioreactor with feed and harvest flow through filter assembly
ITTO20110432A1 (it) 2011-05-16 2011-08-15 Torino Politecnico Dispositivo generatore di microgravità.
EP2766728B1 (de) 2011-10-13 2017-09-06 Boston Heart Diagnostics Zusammensetzungen und verfahren zur behandlung und prävention von koronarer herzkrankheit
US9284521B2 (en) * 2012-03-24 2016-03-15 Therapeutic Proteins International, LLC Pivoting pressurized single-use bioreactor
JP6051730B2 (ja) * 2012-09-24 2016-12-27 東洋製罐グループホールディングス株式会社 気泡除去方法、及び気泡除去装置
KR101470159B1 (ko) 2013-05-21 2014-12-12 연세대학교 원주산학협력단 3차원 회전기와 초음파를 이용한 세포 자극장치 및 세포 자극방법
US9828624B2 (en) 2013-07-24 2017-11-28 Boston Heart Diagnostics Corporation Driving patient compliance with therapy
US9739790B2 (en) 2014-11-17 2017-08-22 Boston Heart Diagnostic Corporation Cardiovascular disease risk assessment
EP3274720B1 (de) * 2015-03-26 2023-12-27 University of Houston System Integrierte funktionale und molekulare profilierung von zellen
JP6884414B2 (ja) 2015-11-04 2021-06-09 スライブ バイオサイエンス, インコーポレイテッド 選択的に透過性の細胞培養容器貯蔵隔室を含む自動細胞培養インキュベータ
US11104874B2 (en) * 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US20180362914A1 (en) * 2017-06-16 2018-12-20 Matthew D. Millard Miniaturized rotating bioreactors
WO2018237132A1 (en) * 2017-06-21 2018-12-27 Board Of Regents, The University Of Texas System VASCULARIZED MICROFLUIDIC PLATFORMS
MA52978A (fr) * 2018-04-10 2021-04-28 Koniku Inc Systèmes universels de code d'odeur et dispositifs de codage d'odeur
IT201800010212A1 (it) 2018-11-09 2020-05-09 Cellex S R L Dispositivo di coltura cellulare in sospensione
EP3760702A1 (de) 2019-07-04 2021-01-06 Celvivo ApS Bioreaktor und bioreaktorsystem für zell- und gewebewachstum
US20210332388A1 (en) * 2020-04-24 2021-10-28 Inscripta, Inc. Compositions, methods, modules and instruments for automated nucleic acid-guided nuclease editing in mammalian cells
CA3200169A1 (en) * 2021-01-21 2022-07-28 Luis Haupt Method of changing culture medium of a culture using spinfilters

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US5153131A (en) * 1990-12-11 1992-10-06 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration High aspect reactor vessel and method of use
US5507949A (en) 1992-03-20 1996-04-16 Monsanto Company Supported liquid membrane and separation process employing same
US5437998A (en) 1993-09-09 1995-08-01 Synthecon, Inc. Gas permeable bioreactor and method of use
US5702941A (en) * 1993-09-09 1997-12-30 Synthecon, Inc. Gas permeable bioreactor and method of use
AU1855397A (en) * 1996-01-31 1997-08-22 Vivorx Pharmaceuticals, Inc. Process for aggregating cells and forming sheets of mammalian tissue in a horizontally rotating bioreactor
US6001642A (en) * 1998-06-29 1999-12-14 Wyle Laboratories, Inc. Life Sciences Bioreactor and cell culturing processes using the bioreactor
US5989913A (en) 1998-07-02 1999-11-23 Charles Daniel Anderson Culture vessel for growing or culturing cells, cellular aggregates, tissues and organoids and methods for using the same
HK1054980A1 (zh) * 2000-06-14 2003-12-19 Vistagen, Inc. 利用肝脏干细胞进行毒性分型
US7198940B2 (en) * 2000-10-25 2007-04-03 Shot Hardware Optimization Technology, Inc. Bioreactor apparatus and cell culturing system
US6607910B1 (en) * 2000-11-13 2003-08-19 Synthecon, Inc. Two chamber cell culture vessel
US6642019B1 (en) * 2000-11-22 2003-11-04 Synthecan, Inc. Vessel, preferably spherical or oblate spherical for growing or culturing cells, cellular aggregates, tissues and organoids and methods for using same
US20040058437A1 (en) * 2001-04-10 2004-03-25 Rodgers Seth T. Materials and reactor systems having humidity and gas control
US20040009495A1 (en) * 2001-12-07 2004-01-15 Whitehead Institute For Biomedical Research Methods and products related to drug screening using gene expression patterns
AU2003217700A1 (en) 2002-02-26 2003-09-09 Stelsys Llc Hepatocyte bioreactor system for long term culture of functional hepatocyte spheroids

Also Published As

Publication number Publication date
EP1966367B1 (de) 2010-03-03
WO2007076865A1 (en) 2007-07-12
JP5042235B2 (ja) 2012-10-03
EP1966367A1 (de) 2008-09-10
US20100120136A1 (en) 2010-05-13
JP2009521907A (ja) 2009-06-11
DK1966367T3 (da) 2010-05-03
DE602006012734D1 (de) 2010-04-15

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