ATE45939T1 - Mischung von diastereoisomeren verbindungen, erhalten aus (-)-5-(1-hydroxy-1-methylaethyl)-2methyl-2-cyclohexen-1-on mit mucosecretolytischer wirkung, ihr herstellungsverfahren und diese enthaltende pharmazeutische kompositionen. - Google Patents

Mischung von diastereoisomeren verbindungen, erhalten aus (-)-5-(1-hydroxy-1-methylaethyl)-2methyl-2-cyclohexen-1-on mit mucosecretolytischer wirkung, ihr herstellungsverfahren und diese enthaltende pharmazeutische kompositionen.

Info

Publication number
ATE45939T1
ATE45939T1 AT85107579T AT85107579T ATE45939T1 AT E45939 T1 ATE45939 T1 AT E45939T1 AT 85107579 T AT85107579 T AT 85107579T AT 85107579 T AT85107579 T AT 85107579T AT E45939 T1 ATE45939 T1 AT E45939T1
Authority
AT
Austria
Prior art keywords
hydroxy
mixture
pharmaceutical compositions
methylaethyl
2methyl
Prior art date
Application number
AT85107579T
Other languages
English (en)
Inventor
Mora Camillo Corvi
Original Assignee
Corvi Camillo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corvi Camillo Spa filed Critical Corvi Camillo Spa
Application granted granted Critical
Publication of ATE45939T1 publication Critical patent/ATE45939T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
    • C07C29/40—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing carbon-to-metal bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C35/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C35/02—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring monocyclic
    • C07C35/08—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring monocyclic containing a six-membered rings
    • C07C35/18—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring monocyclic containing a six-membered rings with unsaturation at least in the ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/29—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
    • C07C45/292—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups with chromium derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
AT85107579T 1984-08-08 1985-06-19 Mischung von diastereoisomeren verbindungen, erhalten aus (-)-5-(1-hydroxy-1-methylaethyl)-2methyl-2-cyclohexen-1-on mit mucosecretolytischer wirkung, ihr herstellungsverfahren und diese enthaltende pharmazeutische kompositionen. ATE45939T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT22257/84A IT1180220B (it) 1984-08-08 1984-08-08 Miscela di composti diastereoisomeri, ottenuti da (-)-5-(1-idrossi-1-metiletil)-2-metil-2-cicloesen-1-one, avente attivita' mucosecretolitica, procedimento per la sua preparazione e composizioni farmaceutiche che la contengono
EP85107579A EP0170839B1 (de) 1984-08-08 1985-06-19 Mischung von diastereoisomeren Verbindungen, erhalten aus (-)-5-(1-Hydroxy-1-methyläthyl)-2-methyl-2-cyclohexen-1-on mit mucosecretolytischer Wirkung, ihr Herstellungsverfahren und diese enthaltende pharmazeutische Kompositionen

Publications (1)

Publication Number Publication Date
ATE45939T1 true ATE45939T1 (de) 1989-09-15

Family

ID=11193758

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85107579T ATE45939T1 (de) 1984-08-08 1985-06-19 Mischung von diastereoisomeren verbindungen, erhalten aus (-)-5-(1-hydroxy-1-methylaethyl)-2methyl-2-cyclohexen-1-on mit mucosecretolytischer wirkung, ihr herstellungsverfahren und diese enthaltende pharmazeutische kompositionen.

Country Status (7)

Country Link
US (1) US4596894A (de)
EP (1) EP0170839B1 (de)
JP (1) JPS6147432A (de)
KR (1) KR920001788B1 (de)
AT (1) ATE45939T1 (de)
DE (1) DE3572649D1 (de)
IT (1) IT1180220B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH681060A5 (de) * 1990-08-22 1993-01-15 Riace Ets
KR102427155B1 (ko) 2015-08-25 2022-07-29 삼성디스플레이 주식회사 레이저 결정화 장치

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2949489A (en) * 1958-06-23 1960-08-16 Fmc Corp Preparation of sobrerol
CH568951A5 (de) * 1970-04-17 1975-11-14 Corvi Camillo Spa

Also Published As

Publication number Publication date
IT1180220B (it) 1987-09-23
KR860001778A (ko) 1986-03-22
DE3572649D1 (en) 1989-10-05
EP0170839B1 (de) 1989-08-30
IT8422257A0 (it) 1984-08-08
JPS647057B2 (de) 1989-02-07
JPS6147432A (ja) 1986-03-07
EP0170839A2 (de) 1986-02-12
US4596894A (en) 1986-06-24
KR920001788B1 (ko) 1992-03-02
EP0170839A3 (en) 1987-06-03

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee