ATE458739T1 - Zweiphasiges verfahren zur synthese ausgewählter pyrazolopyrimidine - Google Patents

Zweiphasiges verfahren zur synthese ausgewählter pyrazolopyrimidine

Info

Publication number
ATE458739T1
ATE458739T1 AT04812693T AT04812693T ATE458739T1 AT E458739 T1 ATE458739 T1 AT E458739T1 AT 04812693 T AT04812693 T AT 04812693T AT 04812693 T AT04812693 T AT 04812693T AT E458739 T1 ATE458739 T1 AT E458739T1
Authority
AT
Austria
Prior art keywords
pyrazolopyrimidines
substituted
pyrimidin
phenyl
salt
Prior art date
Application number
AT04812693T
Other languages
English (en)
Inventor
Gary Lee Cantrell
Frank William Moser
Robert Edward Halvachs
Original Assignee
Mallinckrodt Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Inc filed Critical Mallinckrodt Inc
Application granted granted Critical
Publication of ATE458739T1 publication Critical patent/ATE458739T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT04812693T 2004-01-14 2004-12-02 Zweiphasiges verfahren zur synthese ausgewählter pyrazolopyrimidine ATE458739T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53630204P 2004-01-14 2004-01-14
PCT/US2004/040241 WO2005070931A1 (en) 2004-01-14 2004-12-02 Two-phase method for the synthesis of selected pyrazolopyrimidines

Publications (1)

Publication Number Publication Date
ATE458739T1 true ATE458739T1 (de) 2010-03-15

Family

ID=34806998

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04812693T ATE458739T1 (de) 2004-01-14 2004-12-02 Zweiphasiges verfahren zur synthese ausgewählter pyrazolopyrimidine

Country Status (10)

Country Link
US (1) US7498434B2 (de)
EP (1) EP1713808B1 (de)
JP (1) JP2007517876A (de)
CN (1) CN1906197A (de)
AT (1) ATE458739T1 (de)
AU (1) AU2004314335A1 (de)
CA (1) CA2553465A1 (de)
DE (1) DE602004025747D1 (de)
ES (1) ES2338659T3 (de)
WO (1) WO2005070931A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005099712A2 (en) * 2004-04-19 2005-10-27 Sanmar Speciality Chemicals Limited Process for preparation of n-[3-(3-cyanopyrazolo [1,5-a]pyrimidin-7-yl)phenyl]-n-ethylacetamide
WO2006070244A2 (en) * 2004-11-22 2006-07-06 Bakulesh Mafatlal Khamar A process for the preparation of zaleplon
CN102816163A (zh) * 2012-08-20 2012-12-12 四川禾邦阳光制药股份有限公司 扎来普隆的新晶型及制备方法
AR123884A1 (es) 2020-10-23 2023-01-18 Ildong Pharmaceutical Co Ltd Compuestos moduladores del cftr, composiciones y usos de estos
CN112939987B (zh) * 2021-02-18 2022-03-22 新乡医学院 一种茚地普隆中间体的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4626538A (en) * 1983-06-23 1986-12-02 American Cyanamid Company [7-(3-disubstituted amino)phenyl]pyrazolo[1,5-a]pyrimidines
US5714607A (en) * 1995-12-01 1998-02-03 American Cyanamid Company Process improvement in the synthesis of N- 3-(3-cyano-pyrazolo 1,5-a!pyrimidin-7-yl)phenyl!-N-ethylacetamide
US6399621B1 (en) 1999-08-10 2002-06-04 American Cyanamid Company N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1, 5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto
US6472528B1 (en) 1999-08-10 2002-10-29 Neurocrine Biosciences, Inc. Synthesis of substituted pyrazolopyrimidines
AR029780A1 (es) 2000-12-13 2003-07-16 Gador Sa Procedimiento mejorado para la obtencion de n-[3(3-ciano-pirazolo[1,5-a]pirimidin-7-il)fenil]-n-etil-acetamida
WO2002100828A2 (en) 2001-06-12 2002-12-19 Biogal Gyogyszergyar Rt Process for the production of zaleplon
US6852858B2 (en) 2001-08-01 2005-02-08 Biogal Gyogyszergyar Rt. Process for purifying N-[3-(3-cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-N-ethylacetamide (zaleplon) and crystalline forms of zaleplon accessible with the process

Also Published As

Publication number Publication date
EP1713808B1 (de) 2010-02-24
AU2004314335A1 (en) 2005-08-04
ES2338659T3 (es) 2010-05-11
CA2553465A1 (en) 2005-08-04
US20070155995A1 (en) 2007-07-05
CN1906197A (zh) 2007-01-31
JP2007517876A (ja) 2007-07-05
WO2005070931A1 (en) 2005-08-04
DE602004025747D1 (de) 2010-04-08
EP1713808A1 (de) 2006-10-25
US7498434B2 (en) 2009-03-03

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