ATE458720T1 - Synthese von 2-cyanziridin-1-carbonsäureamid - Google Patents

Synthese von 2-cyanziridin-1-carbonsäureamid

Info

Publication number
ATE458720T1
ATE458720T1 AT02773466T AT02773466T ATE458720T1 AT E458720 T1 ATE458720 T1 AT E458720T1 AT 02773466 T AT02773466 T AT 02773466T AT 02773466 T AT02773466 T AT 02773466T AT E458720 T1 ATE458720 T1 AT E458720T1
Authority
AT
Austria
Prior art keywords
cyanziridine
synthesis
acid amide
carbonic acid
formula
Prior art date
Application number
AT02773466T
Other languages
English (en)
Inventor
William Remers
Bashyam Iyengar
Original Assignee
Univ Arizona
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Arizona filed Critical Univ Arizona
Application granted granted Critical
Publication of ATE458720T1 publication Critical patent/ATE458720T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D203/00Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/16Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with acylated ring nitrogen atoms
    • C07D203/20Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with acylated ring nitrogen atoms by carbonic acid, or by sulfur or nitrogen analogues thereof, e.g. carbamates
AT02773466T 2001-11-26 2002-09-17 Synthese von 2-cyanziridin-1-carbonsäureamid ATE458720T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/995,265 US6476236B1 (en) 2001-11-26 2001-11-26 Synthesis of 2-cyanoaziridine-1-carboxamide
PCT/US2002/029646 WO2003045906A2 (en) 2001-11-26 2002-09-17 Synthesis of 2-cyanoziridine-1-carboxamide

Publications (1)

Publication Number Publication Date
ATE458720T1 true ATE458720T1 (de) 2010-03-15

Family

ID=25541598

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02773466T ATE458720T1 (de) 2001-11-26 2002-09-17 Synthese von 2-cyanziridin-1-carbonsäureamid

Country Status (9)

Country Link
US (1) US6476236B1 (de)
EP (1) EP1461316B1 (de)
JP (1) JP4575666B2 (de)
AT (1) ATE458720T1 (de)
AU (1) AU2002336606B2 (de)
CA (1) CA2468542C (de)
DE (1) DE60235497D1 (de)
ES (1) ES2348473T3 (de)
WO (1) WO2003045906A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6476236B1 (en) * 2001-11-26 2002-11-05 The Arizona Board Of Regents Synthesis of 2-cyanoaziridine-1-carboxamide
MXPA06006291A (es) * 2003-12-08 2006-08-23 Univ Arizona Composiciones anti-cancer sinergisticas.
WO2008045686A2 (en) * 2006-10-12 2008-04-17 The Arizona Board Of Regents On Behalf Of The University Of Arizona Enantiomerically enriched iminopyrrolidone azirdine compositions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE110492C (de) *
DE2530398A1 (de) 1975-07-08 1977-01-27 Boehringer Mannheim Gmbh Organische verbindung
CA1092606A (en) * 1976-10-05 1980-12-30 Herbert Berger 1-(n-acylcarbamoyl)-2-cyano-aziridines and the preparation thereof
AR218645A1 (es) * 1976-12-11 1980-06-30 Boehringer Mannheim Gmbh Procedimiento para preparar derivados de esteres del acido 1-aziridina-carboxilico
US4376731A (en) 1978-01-31 1983-03-15 Boehringer Mannheim Gmbh 1-Aziridine carboxylic acid derivatives with immunostimulant activity
US6476236B1 (en) * 2001-11-26 2002-11-05 The Arizona Board Of Regents Synthesis of 2-cyanoaziridine-1-carboxamide

Also Published As

Publication number Publication date
AU2002336606A1 (en) 2003-06-10
DE60235497D1 (de) 2010-04-08
US6476236B1 (en) 2002-11-05
AU2002336606B2 (en) 2008-05-22
ES2348473T3 (es) 2010-12-07
CA2468542A1 (en) 2003-06-05
CA2468542C (en) 2010-12-07
WO2003045906A2 (en) 2003-06-05
JP2005510561A (ja) 2005-04-21
JP4575666B2 (ja) 2010-11-04
WO2003045906A3 (en) 2003-08-21
EP1461316B1 (de) 2010-02-24
EP1461316A4 (de) 2005-04-27
EP1461316A2 (de) 2004-09-29

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