ATE452908T1 - Il-10 mutante - Google Patents
Il-10 mutanteInfo
- Publication number
- ATE452908T1 ATE452908T1 AT06771553T AT06771553T ATE452908T1 AT E452908 T1 ATE452908 T1 AT E452908T1 AT 06771553 T AT06771553 T AT 06771553T AT 06771553 T AT06771553 T AT 06771553T AT E452908 T1 ATE452908 T1 AT E452908T1
- Authority
- AT
- Austria
- Prior art keywords
- retain
- mutant
- hemoatopoeitic
- polypeptides
- wild
- Prior art date
Links
- 208000012902 Nervous system disease Diseases 0.000 abstract 1
- 208000025966 Neurological disease Diseases 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000028709 inflammatory response Effects 0.000 abstract 1
- 208000004296 neuralgia Diseases 0.000 abstract 1
- 208000021722 neuropathic pain Diseases 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2066—IL-10
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5428—IL-10
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pulmonology (AREA)
- Zoology (AREA)
- Heart & Thoracic Surgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68627205P | 2005-05-31 | 2005-05-31 | |
| PCT/US2006/020863 WO2006130580A2 (en) | 2005-05-31 | 2006-05-26 | Mutant il-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE452908T1 true ATE452908T1 (de) | 2010-01-15 |
Family
ID=37482214
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06771553T ATE452908T1 (de) | 2005-05-31 | 2006-05-26 | Il-10 mutante |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7749490B2 (enExample) |
| EP (1) | EP1891103B1 (enExample) |
| JP (2) | JP4992025B2 (enExample) |
| AT (1) | ATE452908T1 (enExample) |
| CA (1) | CA2609543C (enExample) |
| DE (1) | DE602006011311D1 (enExample) |
| WO (1) | WO2006130580A2 (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE516820T1 (de) | 2000-09-29 | 2011-08-15 | Schering Corp | Pegyliertes interleukin 10 |
| US7261882B2 (en) * | 2003-06-23 | 2007-08-28 | Reagents Of The University Of Colorado | Methods for treating neuropathic pain by administering IL-10 polypeptides |
| DK2816118T3 (en) * | 2005-05-31 | 2018-12-03 | Univ Colorado Regents | Methods for delivery of genes |
| NZ597098A (en) | 2006-09-28 | 2013-05-31 | Merck Sharp & Dohme | Use of pegylated il-10 to treat cancer |
| EP3348281B1 (en) | 2008-12-17 | 2023-07-05 | Merck Sharp & Dohme Corp. | Mono- and di-peg il-10 production; and uses |
| PL2776460T3 (pl) | 2011-11-08 | 2018-10-31 | Umc Utrecht Holding B.V. | Białko fuzyjne zawierające interleukinę 4 i interleukinę 10 |
| US20150044281A1 (en) * | 2012-01-06 | 2015-02-12 | The Regents Of The University Of Colorado, A Body Corporate | Methods for the treatment of multiple sclerosis and other demyelinating disorders |
| CN105209054A (zh) | 2013-04-18 | 2015-12-30 | 阿尔莫生物科技股份有限公司 | 使用白细胞介素-10治疗疾病和病症的方法 |
| CA2908208A1 (en) * | 2013-04-24 | 2014-10-30 | Armo Biosciences, Inc. | Interleukin-10 compositions and uses thereof |
| JP2016528879A (ja) | 2013-06-17 | 2016-09-23 | アルモ・バイオサイエンシーズ・インコーポレイテッド | タンパク質の同一性および安定性を評価する方法 |
| DK3369435T3 (da) * | 2013-07-18 | 2019-11-25 | Xalud Therapeutics Inc | Sammensætning til behandling af inflammatorisk ledsygdom |
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| US6428985B1 (en) | 1998-12-02 | 2002-08-06 | The Regents Of The University Of Michigan | Immunosuppressive structural definition of IL-10 |
| EP1257574A1 (en) * | 2000-02-11 | 2002-11-20 | Maxygen Aps | Improved interleukin 10 |
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| WO2006130580A3 (en) | 2007-04-19 |
| JP2008541759A (ja) | 2008-11-27 |
| US20090035256A1 (en) | 2009-02-05 |
| DE602006011311D1 (de) | 2010-02-04 |
| HK1114107A1 (en) | 2008-10-24 |
| JP4992025B2 (ja) | 2012-08-08 |
| JP2012130344A (ja) | 2012-07-12 |
| CA2609543C (en) | 2015-03-24 |
| US7749490B2 (en) | 2010-07-06 |
| EP1891103A2 (en) | 2008-02-27 |
| CA2609543A1 (en) | 2006-12-07 |
| WO2006130580A2 (en) | 2006-12-07 |
| EP1891103B1 (en) | 2009-12-23 |
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