ATE452908T1 - Il-10 mutante - Google Patents
Il-10 mutanteInfo
- Publication number
- ATE452908T1 ATE452908T1 AT06771553T AT06771553T ATE452908T1 AT E452908 T1 ATE452908 T1 AT E452908T1 AT 06771553 T AT06771553 T AT 06771553T AT 06771553 T AT06771553 T AT 06771553T AT E452908 T1 ATE452908 T1 AT E452908T1
- Authority
- AT
- Austria
- Prior art keywords
- retain
- mutant
- hemoatopoeitic
- polypeptides
- wild
- Prior art date
Links
- 208000012902 Nervous system disease Diseases 0.000 abstract 1
- 208000025966 Neurological disease Diseases 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000028709 inflammatory response Effects 0.000 abstract 1
- 208000004296 neuralgia Diseases 0.000 abstract 1
- 208000021722 neuropathic pain Diseases 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
Classifications
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2066—IL-10
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
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- C07K14/5428—IL-10
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
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- Neurology (AREA)
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- Virology (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Gastroenterology & Hepatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Rheumatology (AREA)
- Toxicology (AREA)
- Hospice & Palliative Care (AREA)
- Obesity (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68627205P | 2005-05-31 | 2005-05-31 | |
| PCT/US2006/020863 WO2006130580A2 (en) | 2005-05-31 | 2006-05-26 | Mutant il-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE452908T1 true ATE452908T1 (de) | 2010-01-15 |
Family
ID=37482214
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06771553T ATE452908T1 (de) | 2005-05-31 | 2006-05-26 | Il-10 mutante |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7749490B2 (enExample) |
| EP (1) | EP1891103B1 (enExample) |
| JP (2) | JP4992025B2 (enExample) |
| AT (1) | ATE452908T1 (enExample) |
| CA (1) | CA2609543C (enExample) |
| DE (1) | DE602006011311D1 (enExample) |
| WO (1) | WO2006130580A2 (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2367891T3 (es) | 2000-09-29 | 2011-11-10 | Schering Corporation | Interleucina-10 pegilada. |
| US7261882B2 (en) * | 2003-06-23 | 2007-08-28 | Reagents Of The University Of Colorado | Methods for treating neuropathic pain by administering IL-10 polypeptides |
| ES2696824T3 (es) * | 2005-05-31 | 2019-01-18 | Univ Colorado Regents | Métodos para suministrar genes |
| EP2066336B1 (en) | 2006-09-28 | 2012-09-19 | Merck Sharp & Dohme Corp. | Use of pegylated il-10 to treat cancer |
| ES2655364T3 (es) | 2008-12-17 | 2018-02-19 | Merck Sharp & Dohme Corp. | Producción de IL-10 mono- y dipegilada y sus usos |
| EP2776460B1 (en) | 2011-11-08 | 2018-05-02 | UMC Utrecht Holding B.V. | Fusion protein comprising an interleukin 4 and interleukin 10 |
| WO2013103966A1 (en) * | 2012-01-06 | 2013-07-11 | The Regents Of The University Of Colorado, A Body Corporate | Methods for the treatment of multiple sclerosis and other demyelinating disorders |
| RU2679889C2 (ru) * | 2013-04-18 | 2019-02-14 | Армо Байосайенсиз, Инк. | Способы применения интерлейкина-10 для лечения заболеваний и расстройств |
| US20160068583A1 (en) * | 2013-04-24 | 2016-03-10 | Armo Biosciences, Inc. | Interleukin-10 Compositions and Uses Thereof |
| US9823255B2 (en) | 2013-06-17 | 2017-11-21 | Armo Biosciences, Inc. | Method for assessing protein identity and stability |
| DK3021873T3 (en) * | 2013-07-18 | 2018-12-17 | Xalud Therapeutics Inc | Composition for the treatment of inflammatory joint disease |
| WO2015031316A1 (en) | 2013-08-30 | 2015-03-05 | Armo Biosciences, Inc. | Methods of using interleukin-10 for treating diseases and disorders |
| CN105848674A (zh) | 2013-11-11 | 2016-08-10 | 阿尔莫生物科技股份有限公司 | 将白细胞介素-10用于治疗疾病和病症的方法 |
| CN106573072A (zh) | 2014-06-02 | 2017-04-19 | 阿尔莫生物科技股份有限公司 | 降低血清胆固醇的方法 |
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| JP7053453B2 (ja) | 2015-08-25 | 2022-04-12 | アルモ・バイオサイエンシーズ・インコーポレイテッド | 疾患及び障害を治療するためのインターロイキン10の使用方法 |
| WO2017160599A1 (en) | 2016-03-14 | 2017-09-21 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Use of cd300b antagonists to treat sepsis and septic shock |
| EP3445849B1 (en) * | 2016-04-22 | 2024-06-05 | Xalud Therapeutics, Inc. | Methods and compositions to enhance the anti-inflammatory effects of interleukin 10 |
| WO2020108426A1 (zh) * | 2018-11-26 | 2020-06-04 | 江苏恒瑞医药股份有限公司 | 一种人白细胞介素10变体及其衍生物 |
| JP2022519586A (ja) * | 2019-02-04 | 2022-03-24 | ゼネティック バイオサイエンシーズ インコーポレイテッド | 糖ポリシアル酸化治療用タンパク質を使用する方法 |
| US12006345B2 (en) | 2019-02-21 | 2024-06-11 | Xencor, Inc. | Untargeted and targeted IL-10 Fc-fusion proteins |
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| WO2021243057A1 (en) * | 2020-05-28 | 2021-12-02 | The Board Of Trustees Of The Leland Stanford Junior University | Engineered interleukin-10 polypeptides and uses thereof |
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|---|---|---|---|---|
| US6428985B1 (en) * | 1998-12-02 | 2002-08-06 | The Regents Of The University Of Michigan | Immunosuppressive structural definition of IL-10 |
| AU2001231532A1 (en) * | 2000-02-11 | 2001-08-20 | Maxygen Aps | Improved interleukin 10 |
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| WO2006130580A2 (en) | 2006-12-07 |
| JP4992025B2 (ja) | 2012-08-08 |
| EP1891103A2 (en) | 2008-02-27 |
| US20090035256A1 (en) | 2009-02-05 |
| WO2006130580A3 (en) | 2007-04-19 |
| US7749490B2 (en) | 2010-07-06 |
| CA2609543C (en) | 2015-03-24 |
| JP2012130344A (ja) | 2012-07-12 |
| DE602006011311D1 (de) | 2010-02-04 |
| CA2609543A1 (en) | 2006-12-07 |
| EP1891103B1 (en) | 2009-12-23 |
| JP2008541759A (ja) | 2008-11-27 |
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