ATE451920T1 - Pulverinhaliermittel mit sumatriptan und herstellungsverfahren dafür - Google Patents

Pulverinhaliermittel mit sumatriptan und herstellungsverfahren dafür

Info

Publication number
ATE451920T1
ATE451920T1 AT03808657T AT03808657T ATE451920T1 AT E451920 T1 ATE451920 T1 AT E451920T1 AT 03808657 T AT03808657 T AT 03808657T AT 03808657 T AT03808657 T AT 03808657T AT E451920 T1 ATE451920 T1 AT E451920T1
Authority
AT
Austria
Prior art keywords
sumatriptan
powder
formulation
drugs
production method
Prior art date
Application number
AT03808657T
Other languages
English (en)
Inventor
Fang Jin
Xusheng Kong
Original Assignee
Shanghai Inst Pharm Industry
Shanghai Sipi Pharmaceutical C
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Inst Pharm Industry, Shanghai Sipi Pharmaceutical C filed Critical Shanghai Inst Pharm Industry
Application granted granted Critical
Publication of ATE451920T1 publication Critical patent/ATE451920T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT03808657T 2002-10-16 2003-07-30 Pulverinhaliermittel mit sumatriptan und herstellungsverfahren dafür ATE451920T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CNB021374724A CN1176649C (zh) 2002-10-16 2002-10-16 舒马普坦干粉吸入剂及其制备方法
PCT/CN2003/000611 WO2004035046A1 (en) 2002-10-16 2003-07-30 Powder inhalant of sumatriptan and the method of preparation thereof

Publications (1)

Publication Number Publication Date
ATE451920T1 true ATE451920T1 (de) 2010-01-15

Family

ID=4749005

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03808657T ATE451920T1 (de) 2002-10-16 2003-07-30 Pulverinhaliermittel mit sumatriptan und herstellungsverfahren dafür

Country Status (6)

Country Link
EP (1) EP1598066B1 (de)
CN (1) CN1176649C (de)
AT (1) ATE451920T1 (de)
AU (1) AU2003248226A1 (de)
DE (1) DE60330601D1 (de)
WO (1) WO2004035046A1 (de)

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KR101273120B1 (ko) 2004-08-20 2013-06-13 맨카인드 코포레이션 다이케토피페라진 합성의 촉매 작용
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KR101486829B1 (ko) 2005-09-14 2015-01-29 맨카인드 코포레이션 결정질 미립자 표면에 대한 활성제의 친화력의 증가를 기반으로 하는 약물 제제의 방법
GB0520794D0 (en) * 2005-10-12 2005-11-23 Innovata Biomed Ltd Inhaler
EP1986679B1 (de) 2006-02-22 2017-10-25 MannKind Corporation Verfahren zur verbesserung der pharmazeutischen eigenschaften von mikropartikeln mit diketopiperazin und einem wirkstoff
GB0613925D0 (en) * 2006-07-13 2006-08-23 Unilever Plc Improvements relating to nanodispersions
US8785396B2 (en) 2007-10-24 2014-07-22 Mannkind Corporation Method and composition for treating migraines
TWI677355B (zh) 2008-06-13 2019-11-21 美商曼凱公司 用於藥物傳輸之乾粉吸入器及系統
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
ES2421385T3 (es) 2008-06-20 2013-09-02 Mannkind Corp Aparato interactivo y procedimiento para establecer el perfil, en tiempo real, de esfuerzos de inhalación
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
EP2676695A3 (de) 2009-03-11 2017-03-01 MannKind Corporation Vorrichtung, System und Verfahren zur Messung des Widerstandes eines Inhalators
JP2012526726A (ja) * 2009-05-15 2012-11-01 株式会社新日本科学 薬物動態が改善された鼻腔内用薬学的組成物
MY186975A (en) 2009-06-12 2021-08-26 Mannkind Corp Diketopiperazine microparticles with defined specific surface areas
US9016147B2 (en) 2009-11-03 2015-04-28 Mannkind Corporation Apparatus and method for simulating inhalation efforts
MX359281B (es) 2010-06-21 2018-09-21 Mannkind Corp Sistema y metodos para suministrar un farmaco en polvo seco.
JP6092113B2 (ja) * 2010-11-09 2017-03-08 マンカインド コーポレイション セロトニン受容体アゴニストおよびジケトピペラジンを含む偏頭痛治療のための組成物
US8925726B2 (en) 2011-04-01 2015-01-06 Mannkind Corporation Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
CN102309469A (zh) * 2011-07-05 2012-01-11 贾晓斌 一种宝藿苷ⅰ干粉吸入剂及其制备方法和用途
CA2852536A1 (en) 2011-10-24 2013-05-02 Mannkind Corporation Methods and compositions for treating pain
CN102440956B (zh) * 2011-12-21 2013-06-05 中国人民解放军第三军医大学 自乳化舒马曲坦及其盐制剂的制备方法
CA2878457C (en) 2012-07-12 2021-01-19 Mannkind Corporation Dry powder drug delivery systems and methods
EP2911690A1 (de) 2012-10-26 2015-09-02 MannKind Corporation Inhalierbare influenza-impfstoffzusammensetzungen und verfahren
CN102988299B (zh) * 2012-11-22 2015-05-20 浦易（上海）生物技术有限公司 一种药物涂层的形成方法及其药物涂层
SI2964199T1 (sl) 2013-03-04 2020-10-30 Besins Healthcare Luxembourg Sarl Suhi farmacevtski sestavki, ki obsegajo nanodelce aktivnega sredstva vezane na nosilne delce
EP2970149B1 (de) 2013-03-15 2019-08-21 MannKind Corporation Mikrokristalline diketopiperazinzusammensetzungen und verfahren
EP3021834A1 (de) 2013-07-18 2016-05-25 MannKind Corporation Hitzestabile pharmazeutische trockenpulverzusammensetzungen und verfahren
CN105517607A (zh) 2013-08-05 2016-04-20 曼金德公司 吹入设备和方法
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
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Also Published As

Publication number Publication date
EP1598066B1 (de) 2009-12-16
DE60330601D1 (de) 2010-01-28
AU2003248226A8 (en) 2004-05-04
EP1598066A1 (de) 2005-11-23
CN1176649C (zh) 2004-11-24
AU2003248226A1 (en) 2004-05-04
EP1598066A4 (de) 2008-07-16
CN1415285A (zh) 2003-05-07
WO2004035046A1 (en) 2004-04-29

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