ATE451920T1 - Pulverinhaliermittel mit sumatriptan und herstellungsverfahren dafür - Google Patents

Pulverinhaliermittel mit sumatriptan und herstellungsverfahren dafür

Info

Publication number
ATE451920T1
ATE451920T1 AT03808657T AT03808657T ATE451920T1 AT E451920 T1 ATE451920 T1 AT E451920T1 AT 03808657 T AT03808657 T AT 03808657T AT 03808657 T AT03808657 T AT 03808657T AT E451920 T1 ATE451920 T1 AT E451920T1
Authority
AT
Austria
Prior art keywords
sumatriptan
powder
formulation
drugs
production method
Prior art date
Application number
AT03808657T
Other languages
English (en)
Inventor
Fang Jin
Xusheng Kong
Original Assignee
Shanghai Inst Pharm Industry
Shanghai Sipi Pharmaceutical C
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Inst Pharm Industry, Shanghai Sipi Pharmaceutical C filed Critical Shanghai Inst Pharm Industry
Application granted granted Critical
Publication of ATE451920T1 publication Critical patent/ATE451920T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT03808657T 2002-10-16 2003-07-30 Pulverinhaliermittel mit sumatriptan und herstellungsverfahren dafür ATE451920T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CNB021374724A CN1176649C (zh) 2002-10-16 2002-10-16 舒马普坦干粉吸入剂及其制备方法
PCT/CN2003/000611 WO2004035046A1 (fr) 2002-10-16 2003-07-30 Inhalant en poudre a base de sumatriptan et son procede de preparation

Publications (1)

Publication Number Publication Date
ATE451920T1 true ATE451920T1 (de) 2010-01-15

Family

ID=4749005

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03808657T ATE451920T1 (de) 2002-10-16 2003-07-30 Pulverinhaliermittel mit sumatriptan und herstellungsverfahren dafür

Country Status (6)

Country Link
EP (1) EP1598066B1 (de)
CN (1) CN1176649C (de)
AT (1) ATE451920T1 (de)
AU (1) AU2003248226A1 (de)
DE (1) DE60330601D1 (de)
WO (1) WO2004035046A1 (de)

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ATE385193T1 (de) 2002-03-20 2008-02-15 Mannkind Corp Inhalationsgerät
WO2005041980A1 (en) * 2003-11-03 2005-05-12 Ivax Corporation Soft steroid compositions for use in dry powder inhalers
KR101273120B1 (ko) 2004-08-20 2013-06-13 맨카인드 코포레이션 다이케토피페라진 합성의 촉매 작용
ES2540886T3 (es) 2004-08-23 2015-07-14 Mannkind Corporation Sales de dicetopiperazina para la administración de fármacos
CN104324366B (zh) 2005-09-14 2016-10-05 曼金德公司 以提高活性试剂对结晶微粒表面的亲和力为基础的药物配制方法
GB0520794D0 (en) * 2005-10-12 2005-11-23 Innovata Biomed Ltd Inhaler
ES2647080T3 (es) 2006-02-22 2017-12-19 Mannkind Corporation Un método para mejorar las propiedades farmacéuticas de micropartículas que comprenden dicetopiperazina y un agente activo
GB0613925D0 (en) 2006-07-13 2006-08-23 Unilever Plc Improvements relating to nanodispersions
US8785396B2 (en) 2007-10-24 2014-07-22 Mannkind Corporation Method and composition for treating migraines
DK2293833T3 (en) 2008-06-13 2016-05-23 Mannkind Corp DRY POWDER INHALER AND MEDICINAL ADMINISTRATION SYSTEM
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
CA2728523C (en) 2008-06-20 2020-03-10 Mannkind Corporation An interactive apparatus and method for real-time profiling of inhalation efforts
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
DK2405963T3 (da) 2009-03-11 2013-12-16 Mannkind Corp Apparat, system og fremgangsmåde til at måle modstand i en inhalator
EP2429495A4 (de) * 2009-05-15 2014-01-22 Shin Nippon Biomedical Lab Ltd Intranasale pharmazeutische zusammensetzung mit verbesserter pharmakokinetik
SG176738A1 (en) 2009-06-12 2012-01-30 Mannkind Corp Diketopiperazine microparticles with defined specific surface areas
EP2496295A1 (de) 2009-11-03 2012-09-12 MannKind Corporation Vorrichtung und verfahren zur simulation von einatmungsanstrengungen
RU2571331C1 (ru) 2010-06-21 2015-12-20 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
EP2637657B1 (de) * 2010-11-09 2019-05-22 MannKind Corporation Zusammensetzung mit einem serotoninrezeptoragonist und einem diketopiperazin zur behandlung von migräne
AU2012236150B2 (en) 2011-04-01 2016-03-31 Mannkind Corporation Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
CN102309469A (zh) * 2011-07-05 2012-01-11 贾晓斌 一种宝藿苷ⅰ干粉吸入剂及其制备方法和用途
BR112014009686A2 (pt) 2011-10-24 2018-08-07 Mannkind Corp composição analgésica inalável, pó seco e método para tratar dor
CN102440956B (zh) * 2011-12-21 2013-06-05 中国人民解放军第三军医大学 自乳化舒马曲坦及其盐制剂的制备方法
CN108057154B (zh) 2012-07-12 2021-04-16 曼金德公司 干粉药物输送系统和方法
EP2911690A1 (de) 2012-10-26 2015-09-02 MannKind Corporation Inhalierbare influenza-impfstoffzusammensetzungen und verfahren
CN102988299B (zh) * 2012-11-22 2015-05-20 浦易（上海）生物技术有限公司 一种药物涂层的形成方法及其药物涂层
JP6564708B2 (ja) 2013-03-04 2019-08-21 ベザン ヘルスケア ルクセンブルク エスエーアールエルＢｅｓｉｎｓ Ｈｅａｌｔｈｃａｒｅ Ｌｕｘｅｍｂｏｕｒｇ Ｓａｒｌ 担体粒子に結合した活性物質ナノ粒子を含む乾燥医薬組成物
US10421729B2 (en) 2013-03-15 2019-09-24 Mannkind Corporation Microcrystalline diketopiperazine compositions and methods
US9925144B2 (en) 2013-07-18 2018-03-27 Mannkind Corporation Heat-stable dry powder pharmaceutical compositions and methods
CA2920488C (en) 2013-08-05 2022-04-26 Mannkind Corporation Insufflation apparatus and methods
WO2015148905A1 (en) 2014-03-28 2015-10-01 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
WO2017004501A1 (en) 2015-07-02 2017-01-05 Civitas Therapeutics, Inc. Triptan powders for pulmonary delivery

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Also Published As

Publication number Publication date
EP1598066A1 (de) 2005-11-23
WO2004035046A1 (fr) 2004-04-29
CN1415285A (zh) 2003-05-07
AU2003248226A8 (en) 2004-05-04
AU2003248226A1 (en) 2004-05-04
EP1598066B1 (de) 2009-12-16
CN1176649C (zh) 2004-11-24
DE60330601D1 (de) 2010-01-28
EP1598066A4 (de) 2008-07-16

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