DE60330601D1 - Pulverinhaliermittel mit sumatriptan und herstellungsverfahren dafür - Google Patents

Pulverinhaliermittel mit sumatriptan und herstellungsverfahren dafür

Info

Publication number
DE60330601D1
DE60330601D1 DE60330601T DE60330601T DE60330601D1 DE 60330601 D1 DE60330601 D1 DE 60330601D1 DE 60330601 T DE60330601 T DE 60330601T DE 60330601 T DE60330601 T DE 60330601T DE 60330601 D1 DE60330601 D1 DE 60330601D1
Authority
DE
Germany
Prior art keywords
sumatriptan
formulation
powder
drugs
manufacturing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60330601T
Other languages
English (en)
Inventor
Fang Jin
Xusheng Kong
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SHANGHAI SIPI PHARMACEUTICAL C
Shanghai Institute of Pharmaceutical Industry
Original Assignee
SHANGHAI SIPI PHARMACEUTICAL C
Shanghai Institute of Pharmaceutical Industry
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SHANGHAI SIPI PHARMACEUTICAL C, Shanghai Institute of Pharmaceutical Industry filed Critical SHANGHAI SIPI PHARMACEUTICAL C
Application granted granted Critical
Publication of DE60330601D1 publication Critical patent/DE60330601D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE60330601T 2002-10-16 2003-07-30 Pulverinhaliermittel mit sumatriptan und herstellungsverfahren dafür Expired - Lifetime DE60330601D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CNB021374724A CN1176649C (zh) 2002-10-16 2002-10-16 舒马普坦干粉吸入剂及其制备方法
PCT/CN2003/000611 WO2004035046A1 (fr) 2002-10-16 2003-07-30 Inhalant en poudre a base de sumatriptan et son procede de preparation

Publications (1)

Publication Number Publication Date
DE60330601D1 true DE60330601D1 (de) 2010-01-28

Family

ID=4749005

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60330601T Expired - Lifetime DE60330601D1 (de) 2002-10-16 2003-07-30 Pulverinhaliermittel mit sumatriptan und herstellungsverfahren dafür

Country Status (6)

Country Link
EP (1) EP1598066B1 (de)
CN (1) CN1176649C (de)
AT (1) ATE451920T1 (de)
AU (1) AU2003248226A1 (de)
DE (1) DE60330601D1 (de)
WO (1) WO2004035046A1 (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2280004B1 (de) 1999-06-29 2016-04-20 MannKind Corporation Pharmazeutische zusammensetzungen enthaltend insulin komplexiert mit diketopiperazin
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US6923175B2 (en) 2002-03-20 2005-08-02 Mannkind Corporation Inhalation apparatus
CA2544422C (en) * 2003-11-03 2010-01-19 Norton Healthcare, Ltd. Soft steroid compositions for use in dry powder inhalers
KR101273120B1 (ko) 2004-08-20 2013-06-13 맨카인드 코포레이션 다이케토피페라진 합성의 촉매 작용
DK1791542T3 (en) 2004-08-23 2015-06-15 Mannkind Corp Diketopiperazinsalte for pharmaceutical delivery
RU2390325C2 (ru) 2005-09-14 2010-05-27 Маннкайнд Корпорейшн Способ приготовления лекарственного препарата, основанный на увеличении сродства активных агентов к поверхностям кристаллических микрочастиц
GB0520794D0 (en) * 2005-10-12 2005-11-23 Innovata Biomed Ltd Inhaler
KR20080096809A (ko) 2006-02-22 2008-11-03 맨카인드 코포레이션 디케토피페라진 및 활성제를 포함하는 마이크로입자의 약학특성의 개선 방법
GB0613925D0 (en) 2006-07-13 2006-08-23 Unilever Plc Improvements relating to nanodispersions
US8785396B2 (en) 2007-10-24 2014-07-22 Mannkind Corporation Method and composition for treating migraines
ES2929343T3 (es) 2008-06-13 2022-11-28 Mannkind Corp Inhalador de polvo seco accionado por aspiración para la administración de fármacos
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
US9364619B2 (en) 2008-06-20 2016-06-14 Mannkind Corporation Interactive apparatus and method for real-time profiling of inhalation efforts
TWI494123B (zh) 2008-08-11 2015-08-01 Mannkind Corp 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
CA2754595C (en) 2009-03-11 2017-06-27 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
JP2012526726A (ja) * 2009-05-15 2012-11-01 株式会社新日本科学 薬物動態が改善された鼻腔内用薬学的組成物
KR20200028501A (ko) 2009-06-12 2020-03-16 맨카인드 코포레이션 한정된 비표면적을 갖는 디케토피페라진 마이크로입자
WO2011056889A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
RU2571331C1 (ru) 2010-06-21 2015-12-20 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
JP6092113B2 (ja) * 2010-11-09 2017-03-08 マンカインド コーポレイション セロトニン受容体アゴニストおよびジケトピペラジンを含む偏頭痛治療のための組成物
EP2694402B1 (de) 2011-04-01 2017-03-22 MannKind Corporation Blisterverpackung für pharmakartuschen
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
CN102309469A (zh) * 2011-07-05 2012-01-11 贾晓斌 一种宝藿苷ⅰ干粉吸入剂及其制备方法和用途
CA2852536A1 (en) 2011-10-24 2013-05-02 Mannkind Corporation Methods and compositions for treating pain
CN102440956B (zh) * 2011-12-21 2013-06-05 中国人民解放军第三军医大学 自乳化舒马曲坦及其盐制剂的制备方法
JP6312262B2 (ja) 2012-07-12 2018-04-18 マンカインド コーポレイション 乾燥粉末薬物送達システム
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
CN102988299B (zh) * 2012-11-22 2015-05-20 浦易（上海）生物技术有限公司 一种药物涂层的形成方法及其药物涂层
AU2014226192B2 (en) 2013-03-04 2018-07-26 Besins Healthcare Luxembourg Sarl Dry pharmaceutical compositions comprising active agent nanoparticles bound to carrier particles
EP3587404B1 (de) 2013-03-15 2022-07-13 MannKind Corporation Mikrokristalline diketopiperazinzusammensetzungen, verfahren zur herstellung und deren verwendung
BR112016000937A8 (pt) 2013-07-18 2021-06-22 Mannkind Corp formulações farmacêuticas de pó seco, método para a fabricação de uma formulação de pó seco e uso de uma formulação farmacêutica de pó seco
JP2016530930A (ja) 2013-08-05 2016-10-06 マンカインド コーポレイション 通気装置及び方法
WO2015148905A1 (en) 2014-03-28 2015-10-01 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
AU2016287582B2 (en) 2015-07-02 2020-03-12 Civitas Therapeutics, Inc. Triptan powders for pulmonary delivery

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8419575D0 (en) * 1984-08-01 1984-09-05 Glaxo Group Ltd Chemical compounds
GB9101592D0 (en) 1991-01-24 1991-03-06 Glaxo Group Ltd Compositions
AUPN976496A0 (en) * 1996-05-10 1996-05-30 Glaxo Wellcome Australia Ltd Unit dose dispensing device
CN1225018A (zh) * 1996-07-11 1999-08-04 荷兰发马克有限公司 含有吲哚选择性的5－羟色胺激动剂的包合配合物
US5921447A (en) * 1997-02-13 1999-07-13 Glaxo Wellcome Inc. Flow-through metered aerosol dispensing apparatus and method of use thereof
GB9816556D0 (en) * 1998-07-30 1998-09-30 Pfizer Ltd Therapy
ITMI20012174A1 (it) * 2001-10-18 2003-04-18 Univ Parma Polvere per somministrazione nasale di farmaci

Also Published As

Publication number Publication date
EP1598066B1 (de) 2009-12-16
AU2003248226A1 (en) 2004-05-04
WO2004035046A1 (fr) 2004-04-29
EP1598066A1 (de) 2005-11-23
CN1176649C (zh) 2004-11-24
AU2003248226A8 (en) 2004-05-04
CN1415285A (zh) 2003-05-07
EP1598066A4 (de) 2008-07-16
ATE451920T1 (de) 2010-01-15

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Legal Events

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