ATE449787T1 - Tumorantigene und ctl-klone, die durch ein neues verfahren isoliert wurden - Google Patents

Tumorantigene und ctl-klone, die durch ein neues verfahren isoliert wurden

Info

Publication number
ATE449787T1
ATE449787T1 AT99970091T AT99970091T ATE449787T1 AT E449787 T1 ATE449787 T1 AT E449787T1 AT 99970091 T AT99970091 T AT 99970091T AT 99970091 T AT99970091 T AT 99970091T AT E449787 T1 ATE449787 T1 AT E449787T1
Authority
AT
Austria
Prior art keywords
present
mage
ctl clones
isolated
ctl
Prior art date
Application number
AT99970091T
Other languages
English (en)
Inventor
Pascal Chaux
Rosalie Luiten
Nathalie Demotte
Marie-Therese Duffour
Christophe Lurquin
Catia Traversari
Vincent Stroobant
Guy Cornelis
Thierry Boon-Falleur
Der Bruggen Pierre Van
Erwin Schultz
Guy Warnier
Original Assignee
Ludwig Inst Cancer Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ludwig Inst Cancer Res filed Critical Ludwig Inst Cancer Res
Priority claimed from PCT/IB1999/001664 external-priority patent/WO2000020445A2/en
Application granted granted Critical
Publication of ATE449787T1 publication Critical patent/ATE449787T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT99970091T 1998-10-02 1999-09-15 Tumorantigene und ctl-klone, die durch ein neues verfahren isoliert wurden ATE449787T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/165,863 US6407063B1 (en) 1998-10-02 1998-10-02 Tumor antigens and CTL clones isolated by a novel procedure
US09/289,350 US6531451B1 (en) 1998-10-02 1999-04-09 Tumor antigens and CTL clones isolated by a novel procedure
PCT/IB1999/001664 WO2000020445A2 (en) 1998-10-02 1999-09-15 Tumor antigens and ctl clones isolated by a novel procedure

Publications (1)

Publication Number Publication Date
ATE449787T1 true ATE449787T1 (de) 2009-12-15

Family

ID=22600796

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99970091T ATE449787T1 (de) 1998-10-02 1999-09-15 Tumorantigene und ctl-klone, die durch ein neues verfahren isoliert wurden

Country Status (4)

Country Link
US (2) US6407063B1 (de)
JP (1) JP4722289B2 (de)
AT (1) ATE449787T1 (de)
DE (1) DE69941719D1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69533295T3 (de) * 1994-02-16 2009-07-16 The Government Of The United States Of America, As Represented By The Secretary, The Department Of Health And Human Services Melanoma-assoziierte Antigene, Epitope davon und Impstoffe gegen Melanoma
US20040156861A1 (en) * 1996-07-11 2004-08-12 Figdor Carl Gustav Melanoma associated peptide analogues and vaccines against melanoma
US5965381A (en) * 1998-03-06 1999-10-12 Ludwig Institute For Cancer Research Delivery of proteins into eukaryotic cells with recombinant yersinia
JP2003512829A (ja) 1999-10-22 2003-04-08 アヴェンティス パストゥール リミテッド 改変型gp100およびその使用
EP1741782B1 (de) * 2000-05-10 2011-06-22 Sanofi Pasteur Limited Durch Mage Minigene kodierte immunogene Polypeptide und ihre Verwendungen
WO2005035773A2 (en) * 2003-10-08 2005-04-21 Sanofi Pasteur, Inc. Modified cea /b7 vector
PT1496939E (pt) * 2002-04-09 2007-11-22 Sanofi Pasteur Ltd ''ácido nucleico de cea modificado e vectores de expressão''
EP1556082A1 (de) * 2002-10-22 2005-07-27 Aventis Pasteur Limited Impfstoffe gegen krebs mit hochdosierten zytokinen als adjuvans
CA2547635C (en) * 2003-12-12 2016-02-09 Jeffrey Schlom A human cytotoxic t-lymphocyte epitope and its agonist epitope from the non-variable number of tandem repeat sequence of muc-1
WO2006088492A2 (en) * 2004-07-01 2006-08-24 The Regents Of The University Of Califorrnia High throughput proteomics
CN101041816B (zh) * 2006-12-01 2010-08-25 扬州大学 人工抗原递呈细胞及其制备方法
US8313894B2 (en) 2008-07-01 2012-11-20 Genocea Biosciences, Inc. Antigen screening system
EP3925972A1 (de) * 2016-04-08 2021-12-22 Adaptimmune Ltd T-zell-rezeptoren
KR20190142767A (ko) 2017-03-20 2019-12-27 제노세아 바이오사이언스, 인코퍼레이티드 치료 방법
WO2019241315A1 (en) 2018-06-12 2019-12-19 Obsidian Therapeutics, Inc. Pde5 derived regulatory constructs and methods of use in immunotherapy
KR20210148106A (ko) 2019-03-08 2021-12-07 옵시디안 테라퓨틱스, 인크. 조정 가능한 조절을 위한 cd40l 조성물 및 방법
CN113966397A (zh) 2019-03-08 2022-01-21 黑曜石疗法公司 人碳酸酐酶2组合物和用于可调调节的方法
US20200318068A1 (en) * 2019-04-04 2020-10-08 Immatics US, Inc. Use of retinoic acid in t-cell manufacturing
CA3140668A1 (en) 2019-06-12 2020-12-17 Obsidian Therapeutics, Inc. Ca2 compositions and methods for tunable regulation
US20220267398A1 (en) 2019-06-12 2022-08-25 Obsidian Therapeutics, Inc. Ca2 compositions and methods for tunable regulation
US20230092895A1 (en) 2019-08-30 2023-03-23 Obsidian Therapeutics, Inc. Tandem cd19 car-based compositions and methods for immunotherapy
CN114651003A (zh) 2019-09-10 2022-06-21 黑曜石疗法公司 用于可调调节的ca2-il15融合蛋白
WO2021142376A1 (en) 2020-01-08 2021-07-15 Obsidian Therapeutics, Inc. Compositions and methods for tunable regulation of transcription
CN111534546A (zh) * 2020-05-09 2020-08-14 赛诺(深圳)生物医药研究有限公司 一种具有多等位基因p53编码序列的重组腺病毒的制备方法
WO2022060806A1 (en) 2020-09-16 2022-03-24 Obsidian Therapeutics, Inc. Compositions and methods for expression of anti-bcma chimeric antigen receptors with small molecule-regulated il15 in t cells

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4769330A (en) 1981-12-24 1988-09-06 Health Research, Incorporated Modified vaccinia virus and methods for making and using the same
US5342774A (en) 1991-05-23 1994-08-30 Ludwig Institute For Cancer Research Nucleotide sequence encoding the tumor rejection antigen precursor, MAGE-1
US5925729A (en) * 1991-05-23 1999-07-20 Ludwig Institute For Cancer Research Tumor rejection antigen precursors, tumor rejection antigens and uses thereof
AU4998993A (en) 1992-08-07 1994-03-03 Epimmune, Inc. Hla binding peptides and their uses
US5558995A (en) 1993-01-22 1996-09-24 Ludwig Institute For Cancer Research Peptides which are derived from tumor rejection antigen precursor molecule MAGE-1, which complex to MHC molecule HLA-C clone 10, and uses thereof
US6328971B1 (en) 1993-01-22 2001-12-11 Ludwig Institute For Cancer Research MAGE-1 derived nona peptides, and compositions thereof
JPH09502086A (ja) * 1993-08-06 1997-03-04 サイテル コーポレイション 完全mage1遺伝子のクローニング及び特性決定
EP0879282B1 (de) * 1996-01-17 2003-07-02 Imperial College Innovations Limited Immunotherapie mit verwendung von zytotoxischen t lymphozyten (ctl)
US6265215B1 (en) 1996-09-13 2001-07-24 Ludwig Institute For Cancer Research Isolated peptides which complex with HLA-Cw16 and uses thereof
US5965535A (en) 1997-09-12 1999-10-12 Ludwig Institute For Cancer Research Mage-3 peptides presented by HLA class II molecules
CA2323632A1 (en) 1998-03-13 1999-09-16 Epimmune Inc. Hla-binding peptides and their uses

Also Published As

Publication number Publication date
JP2003518911A (ja) 2003-06-17
US6531451B1 (en) 2003-03-11
JP4722289B2 (ja) 2011-07-13
DE69941719D1 (de) 2010-01-07
US6407063B1 (en) 2002-06-18

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