ATE448220T1 - Heterocyclische modulatoren für den gaba-alpha- subtyp-selektiven rezeptor - Google Patents
Heterocyclische modulatoren für den gaba-alpha- subtyp-selektiven rezeptorInfo
- Publication number
- ATE448220T1 ATE448220T1 AT07727623T AT07727623T ATE448220T1 AT E448220 T1 ATE448220 T1 AT E448220T1 AT 07727623 T AT07727623 T AT 07727623T AT 07727623 T AT07727623 T AT 07727623T AT E448220 T1 ATE448220 T1 AT E448220T1
- Authority
- AT
- Austria
- Prior art keywords
- gaba
- selective receptor
- subtype selective
- alpha subtype
- heterocyclic modulators
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Liquid Crystal (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79126406P | 2006-04-11 | 2006-04-11 | |
| PCT/EP2007/053151 WO2007115966A1 (en) | 2006-04-11 | 2007-04-02 | Heterocyclic gaba alpha subtype selective receptor modulators |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE448220T1 true ATE448220T1 (de) | 2009-11-15 |
Family
ID=38255492
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07727623T ATE448220T1 (de) | 2006-04-11 | 2007-04-02 | Heterocyclische modulatoren für den gaba-alpha- subtyp-selektiven rezeptor |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20070238765A1 (de) |
| EP (1) | EP2007753B1 (de) |
| JP (1) | JP2009533376A (de) |
| KR (1) | KR20080100390A (de) |
| CN (1) | CN101466703A (de) |
| AT (1) | ATE448220T1 (de) |
| AU (1) | AU2007235994A1 (de) |
| BR (1) | BRPI0709983A2 (de) |
| CA (1) | CA2648168A1 (de) |
| DE (1) | DE602007003207D1 (de) |
| ES (1) | ES2333680T3 (de) |
| IL (1) | IL194390A0 (de) |
| MX (1) | MX2008012952A (de) |
| WO (1) | WO2007115966A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10449181B2 (en) | 2016-08-25 | 2019-10-22 | Sarah E. Labance | Treatment of autism and autism spectrum disorders (ASD) |
| CN110183456A (zh) * | 2019-07-11 | 2019-08-30 | 河南师范大学 | 一种2-芳基吲唑琥珀酰亚胺螺环化合物的合成方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1453832B1 (de) * | 2001-12-04 | 2006-08-09 | F. Hoffmann-La Roche AG | Ringannelierte pyrazolderivate |
| PL377609A1 (pl) * | 2002-12-02 | 2006-02-06 | F. Hoffmann-La Roche Ag | Pochodne indazolu jako antagoniści CRF |
| AU2004265101B2 (en) * | 2003-08-14 | 2009-06-11 | F. Hoffmann-La Roche Ag | Gabanergic modulators |
| BRPI0417323A (pt) * | 2003-12-22 | 2007-03-27 | Memory Pharm Corp | indóis, 1h-indazóis, 1,2-benzisoxazóis, e 1,2-benzisotiazóis, composto, composição farmacêutica e usos dos mesmos |
| CN1921854A (zh) * | 2004-02-18 | 2007-02-28 | 弗·哈夫曼-拉罗切有限公司 | 杂环gaba－a亚型选择性受体调节剂 |
-
2007
- 2007-04-02 ES ES07727623T patent/ES2333680T3/es active Active
- 2007-04-02 AT AT07727623T patent/ATE448220T1/de active
- 2007-04-02 BR BRPI0709983-5A patent/BRPI0709983A2/pt not_active IP Right Cessation
- 2007-04-02 KR KR1020087024752A patent/KR20080100390A/ko active IP Right Grant
- 2007-04-02 AU AU2007235994A patent/AU2007235994A1/en not_active Abandoned
- 2007-04-02 MX MX2008012952A patent/MX2008012952A/es active IP Right Grant
- 2007-04-02 WO PCT/EP2007/053151 patent/WO2007115966A1/en active Application Filing
- 2007-04-02 EP EP07727623A patent/EP2007753B1/de active Active
- 2007-04-02 JP JP2009504688A patent/JP2009533376A/ja active Pending
- 2007-04-02 CA CA002648168A patent/CA2648168A1/en not_active Abandoned
- 2007-04-02 DE DE602007003207T patent/DE602007003207D1/de active Active
- 2007-04-02 CN CNA2007800215938A patent/CN101466703A/zh active Pending
- 2007-04-11 US US11/786,342 patent/US20070238765A1/en not_active Abandoned
-
2008
- 2008-09-25 IL IL194390A patent/IL194390A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL194390A0 (en) | 2009-08-03 |
| WO2007115966A1 (en) | 2007-10-18 |
| JP2009533376A (ja) | 2009-09-17 |
| MX2008012952A (es) | 2008-10-15 |
| KR20080100390A (ko) | 2008-11-17 |
| BRPI0709983A2 (pt) | 2011-08-02 |
| US20070238765A1 (en) | 2007-10-11 |
| AU2007235994A1 (en) | 2007-10-18 |
| CA2648168A1 (en) | 2007-10-18 |
| CN101466703A (zh) | 2009-06-24 |
| EP2007753B1 (de) | 2009-11-11 |
| DE602007003207D1 (de) | 2009-12-24 |
| ES2333680T3 (es) | 2010-02-25 |
| EP2007753A1 (de) | 2008-12-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| UA94964C2 (ru) | Производные 5-замещенного хиназолинона, композиция, которая их содержит, и их применение | |
| ATE496620T1 (de) | 1h-benzo(f)indazol-5-yl-derivate als selektive glucocorticoid-rezeptor-modulatoren | |
| EA200970585A1 (ru) | Бензамидные производные как агонисты ер-рецепторов | |
| WO2007117465A3 (en) | Indazole compounds | |
| TW200734322A (en) | Indole derivatives exhibiting PGD2 receptor antagonism | |
| NO20081554L (no) | Isoindollmidforbindelser og sammensetninger omfattende samme, og anvendelse derav | |
| UA97976C2 (ru) | 4'-о-замещенные изоиндолиновые производные и содержащие их композиции, и способы их применения | |
| EA200900135A1 (ru) | Производные пиразола в качестве ингибиторов цитохрома р450 | |
| MY151986A (en) | Adamantyl diamide derivatives and uses of same | |
| NO20091741L (no) | Pyrazolinforbindelser som mineralkortikoidreceptorantagonister | |
| DE602004009200D1 (de) | Tetrahydrochinazolinderivate als cfr-antagonisten | |
| PL1831191T3 (pl) | Pochodne chromanu i ich zastosowanie jako ligandów receptorów 5-HT | |
| MY139612A (en) | Benzoxazine derivatives as 5-th6 modulators and uses thereof | |
| WO2007103762A3 (en) | Compositions and methods of use of electron transport system inhibitors | |
| TW200738697A (en) | Benzimidazole derivatives as 5-HT6,5-HT24 | |
| MA32834B1 (fr) | 3-aminocyclopentanecarboxamides servant de modulateurs de recepteurs de chimiokines | |
| MXPA05009523A (es) | Derivados de quinolina/benzoxazinona y sus usos. | |
| DE602004023926D1 (de) | Selektive spirocyclische glucocorticoid-rezeptor-modulatoren | |
| SI1845780T1 (sl) | Uporaba derivatov metilfenidata | |
| TW200738625A (en) | 3-Amino-1-arylpropyl indoles and aza-substituted indoles | |
| ATE465151T1 (de) | 4-aryloxy-chinolin-derivate als 5-ht6-modulatoren | |
| ATE448220T1 (de) | Heterocyclische modulatoren für den gaba-alpha- subtyp-selektiven rezeptor | |
| MX2010007929A (es) | Imidazolinilmetil aril sulfonamidas novedosas. | |
| EA200970189A1 (ru) | Пирролидинонанилины как модуляторы прогестероновых рецепторов | |
| MX2009001572A (es) | Derivados de arilpiperazina y usos de los mismos. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 2007753 Country of ref document: EP |