MX2010007929A - Imidazolinilmetil aril sulfonamidas novedosas. - Google Patents

Imidazolinilmetil aril sulfonamidas novedosas.

Info

Publication number
MX2010007929A
MX2010007929A MX2010007929A MX2010007929A MX2010007929A MX 2010007929 A MX2010007929 A MX 2010007929A MX 2010007929 A MX2010007929 A MX 2010007929A MX 2010007929 A MX2010007929 A MX 2010007929A MX 2010007929 A MX2010007929 A MX 2010007929A
Authority
MX
Mexico
Prior art keywords
novel
aryl sulfonamides
imidazolinylmethyl
imidazolinylmethyl aryl
methods
Prior art date
Application number
MX2010007929A
Other languages
English (en)
Inventor
Counde O'yang
Robert Greenhouse
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MX2010007929A publication Critical patent/MX2010007929A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/24—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Esta invención se refiere a un agonista parcial del receptor alfa-1A, que está representado por la fórmula (I) y a las sales o solvatos del mismo farmacéuticamente aceptables. La invención se refiere además a composiciones farmacéuticas que contienen la fórmula I, a métodos para su uso como agentes terapéuticos, y a métodos de preparación de los mismos.
MX2010007929A 2008-02-04 2009-01-26 Imidazolinilmetil aril sulfonamidas novedosas. MX2010007929A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2584108P 2008-02-04 2008-02-04
PCT/EP2009/050841 WO2009098136A1 (en) 2008-02-04 2009-01-26 Novel imidazolinylmethyl aryl sulfonamides

Publications (1)

Publication Number Publication Date
MX2010007929A true MX2010007929A (es) 2010-08-09

Family

ID=40679581

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010007929A MX2010007929A (es) 2008-02-04 2009-01-26 Imidazolinilmetil aril sulfonamidas novedosas.

Country Status (12)

Country Link
US (2) US20090197934A1 (es)
EP (1) EP2238116B1 (es)
JP (1) JP2011511026A (es)
KR (1) KR20100096262A (es)
CN (1) CN101925581A (es)
AT (1) ATE525360T1 (es)
AU (1) AU2009211506A1 (es)
BR (1) BRPI0906632A2 (es)
CA (1) CA2711728A1 (es)
IL (1) IL206611A0 (es)
MX (1) MX2010007929A (es)
WO (1) WO2009098136A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021081292A1 (en) * 2019-10-25 2021-04-29 Curasen Therapeutics, Inc. METHODS FOR TREATING NEUROLOGICAL DISORDERS WITH α1A-AR PARTIAL AGONISTS
MX2023002276A (es) * 2020-08-27 2023-03-10 Curasen Therapeutics Inc Agonistas del receptor adrenérgico a1a y métodos de uso.
CN112624975A (zh) * 2020-11-27 2021-04-09 华南农业大学 一种妥拉唑林半抗原、人工抗原、抗体及其制备和应用
CN117229291B (zh) * 2023-11-10 2024-03-15 山东大学 内体-溶酶体转运靶向嵌合体降解剂及其制备方法与应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG72827A1 (en) * 1997-06-23 2000-05-23 Hoffmann La Roche Phenyl-and aminophenyl-alkylsulfonamide and urea derivatives
MXPA04010315A (es) * 2002-04-23 2005-06-08 Hoffmann La Roche Imidazolinilmetil aralquilsulfonamidas.
EP2238113A1 (en) * 2008-02-04 2010-10-13 F. Hoffmann-La Roche AG N-[3-bromo-2-chloro-4-(4, 5-dihydro-1h-imidazol-2-ylmethyl)-phenyl] -methanesulfoamide as alpha-1 a adrenergic partial agonist for the treatment of incontinence
AU2009211505A1 (en) * 2008-02-04 2009-08-13 F. Hoffmann-La Roche Ag Novel imidazolinylmethyl aryl sulfonamides

Also Published As

Publication number Publication date
AU2009211506A1 (en) 2009-08-13
EP2238116A1 (en) 2010-10-13
JP2011511026A (ja) 2011-04-07
WO2009098136A1 (en) 2009-08-13
KR20100096262A (ko) 2010-09-01
ATE525360T1 (de) 2011-10-15
CN101925581A (zh) 2010-12-22
CA2711728A1 (en) 2009-07-13
IL206611A0 (en) 2010-12-30
BRPI0906632A2 (pt) 2015-07-14
EP2238116B1 (en) 2011-09-21
US20110230535A1 (en) 2011-09-22
US20090197934A1 (en) 2009-08-06

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal