BRPI0906632A2 - Imidazolinil metil aril sulfonamidas - Google Patents

Imidazolinil metil aril sulfonamidas

Info

Publication number
BRPI0906632A2
BRPI0906632A2 BRPI0906632-2A BRPI0906632A BRPI0906632A2 BR PI0906632 A2 BRPI0906632 A2 BR PI0906632A2 BR PI0906632 A BRPI0906632 A BR PI0906632A BR PI0906632 A2 BRPI0906632 A2 BR PI0906632A2
Authority
BR
Brazil
Prior art keywords
methyl aryl
aryl sulfonamides
imidazolinyl
imidazolinyl methyl
methods
Prior art date
Application number
BRPI0906632-2A
Other languages
English (en)
Inventor
Robert Greenhouse
Counde O'yang
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BRPI0906632A2 publication Critical patent/BRPI0906632A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/24—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
BRPI0906632-2A 2008-02-04 2009-01-26 Imidazolinil metil aril sulfonamidas BRPI0906632A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2584108P 2008-02-04 2008-02-04
PCT/EP2009/050841 WO2009098136A1 (en) 2008-02-04 2009-01-26 Novel imidazolinylmethyl aryl sulfonamides

Publications (1)

Publication Number Publication Date
BRPI0906632A2 true BRPI0906632A2 (pt) 2015-07-14

Family

ID=40679581

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0906632-2A BRPI0906632A2 (pt) 2008-02-04 2009-01-26 Imidazolinil metil aril sulfonamidas

Country Status (12)

Country Link
US (2) US20090197934A1 (pt)
EP (1) EP2238116B1 (pt)
JP (1) JP2011511026A (pt)
KR (1) KR20100096262A (pt)
CN (1) CN101925581A (pt)
AT (1) ATE525360T1 (pt)
AU (1) AU2009211506A1 (pt)
BR (1) BRPI0906632A2 (pt)
CA (1) CA2711728A1 (pt)
IL (1) IL206611A0 (pt)
MX (1) MX2010007929A (pt)
WO (1) WO2009098136A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4048263A4 (en) * 2019-10-25 2023-11-15 Curasen Therapeutics, Inc. METHODS OF TREATING NEUROLOGICAL DISORDERS WITH PARTIAL ALPHA 1A-AR AGONISTS
CN115884964A (zh) * 2020-08-27 2023-03-31 库拉森疗法公司 α1A-肾上腺素能受体激动剂和使用方法
CN112624975A (zh) * 2020-11-27 2021-04-09 华南农业大学 一种妥拉唑林半抗原、人工抗原、抗体及其制备和应用
CN117229291B (zh) * 2023-11-10 2024-03-15 山东大学 内体-溶酶体转运靶向嵌合体降解剂及其制备方法与应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG72827A1 (en) * 1997-06-23 2000-05-23 Hoffmann La Roche Phenyl-and aminophenyl-alkylsulfonamide and urea derivatives
CN1296365C (zh) * 2002-04-23 2007-01-24 弗·哈夫曼-拉罗切有限公司 咪唑啉基甲基芳烷基磺酰胺
JP2011511025A (ja) * 2008-02-04 2011-04-07 エフ．ホフマン−ラ ロシュ アーゲー 新規イミダゾリニルメチルアリールスルホンアミド
EP2238113A1 (en) * 2008-02-04 2010-10-13 F. Hoffmann-La Roche AG N-[3-bromo-2-chloro-4-(4, 5-dihydro-1h-imidazol-2-ylmethyl)-phenyl] -methanesulfoamide as alpha-1 a adrenergic partial agonist for the treatment of incontinence

Also Published As

Publication number Publication date
MX2010007929A (es) 2010-08-09
US20090197934A1 (en) 2009-08-06
JP2011511026A (ja) 2011-04-07
KR20100096262A (ko) 2010-09-01
CA2711728A1 (en) 2009-07-13
ATE525360T1 (de) 2011-10-15
WO2009098136A1 (en) 2009-08-13
CN101925581A (zh) 2010-12-22
US20110230535A1 (en) 2011-09-22
IL206611A0 (en) 2010-12-30
AU2009211506A1 (en) 2009-08-13
EP2238116A1 (en) 2010-10-13
EP2238116B1 (en) 2011-09-21

Similar Documents

Publication Publication Date Title
EA201001724A1 (ru) Производные изоксазола и их применение в качестве потенциирующих средств для метаботропных глутаматных рецепторов
EA201390766A1 (ru) БЕНЗОКСАЗЕПИНЫ КАК ИНГИБИТОРЫ PI3K/mTOR И СПОСОБЫ ИХ ИСПОЛЬЗОВАНИЯ И ПОЛУЧЕНИЯ
EA201390908A1 (ru) Производные бицикло[3.2.1]октиламида и их применение
EA200970156A1 (ru) Пиридизиноновые производные
ATE517882T1 (de) Chinolinderivate
DE602006006712D1 (de) Thiazolylpiperidin-derivate nützlich als h3 rezeptor modulatoren
EA201170922A1 (ru) Производные сульфонамида
EA201071329A1 (ru) Диамидные производные адамантана и их применение
EA201071288A1 (ru) Тризамещенные пиразолы в качестве модуляторов рецепторов ацетилхолина
EA201692167A1 (ru) Модуляторы толл-подобных рецепторов
EA201401351A1 (ru) Производные бензимидазол-пролина
DE602006009773D1 (de) Substituierte thiophenderivate als glucagonrezeptorantagonisten, herstellung und therapeutische anwendungen
EA200970967A1 (ru) Оксадиазол замещенные производные индазола для применения в качестве агонистов сфингозин 1-фосфата (sip)
EA201290394A1 (ru) Морфолинотиазолы в качестве позитивных аллостерических модуляторов альфа 7
EA201490471A1 (ru) Пиридазиноновые соединения и их применение в качестве ингибиторов daao
EA201390163A1 (ru) Гетеробициклические производные в качетстве ингибиторов hcv
EA201070327A1 (ru) Катехоламиновые производные и их пролекарства
EA200970341A1 (ru) Пиразолиновые соединения в качестве антагонистов минералокортикоидных рецепторов
EA201190017A1 (ru) Аминоэфирные производные алкалоидов и их медицинские композиции
DE602006018713D1 (de) Als agonisten für den nikotinischen acetylcholinrezeptor geeignete azabicycloalkanderivate
MX353209B (es) Antagonistas d2, metodos de sintesis y metodos de uso.
EA201300436A8 (ru) Совместные кристаллы и соли ингибиторов ccr3
EA200970065A1 (ru) Производные пиперазинила, предназначенные для лечения заболеваний, опосредованных рецептором gpr38
EA201001747A1 (ru) Бензоксазиноновые производные, действующие в качестве агониста бета-2-адренорецептора, для лечения респираторных расстройств
EA201992679A1 (ru) N-замещенные индольные производные

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2344 DE 08-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.