ATE447964T1 - Eine pharmazeutische formulierung, enthaltend einen inhibitor der carboxypeptidase a und einen thrombin-inhibitor - Google Patents

Eine pharmazeutische formulierung, enthaltend einen inhibitor der carboxypeptidase a und einen thrombin-inhibitor

Info

Publication number
ATE447964T1
ATE447964T1 AT00925845T AT00925845T ATE447964T1 AT E447964 T1 ATE447964 T1 AT E447964T1 AT 00925845 T AT00925845 T AT 00925845T AT 00925845 T AT00925845 T AT 00925845T AT E447964 T1 ATE447964 T1 AT E447964T1
Authority
AT
Austria
Prior art keywords
inhibitor
carboxypeptidase
pharmaceutical formulation
formulation containing
thrombin
Prior art date
Application number
AT00925845T
Other languages
English (en)
Inventor
Tommy Abrahamsson
Viveca Nerme
Magnus Polla
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9901572A external-priority patent/SE9901572D0/xx
Priority claimed from SE9901573A external-priority patent/SE9901573D0/xx
Priority claimed from SE9902902A external-priority patent/SE9902902D0/xx
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE447964T1 publication Critical patent/ATE447964T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT00925845T 1999-05-03 2000-05-03 Eine pharmazeutische formulierung, enthaltend einen inhibitor der carboxypeptidase a und einen thrombin-inhibitor ATE447964T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE9901572A SE9901572D0 (sv) 1999-05-03 1999-05-03 New compounds
SE9901573A SE9901573D0 (sv) 1999-05-03 1999-05-03 New compounds
SE9902902A SE9902902D0 (sv) 1999-08-13 1999-08-13 New formulation
PCT/SE2000/000847 WO2000066152A1 (en) 1999-05-03 2000-05-03 A pharmaceutical formulation containing an inhibitor of carboxypeptidase u and a thrombin inhibitor

Publications (1)

Publication Number Publication Date
ATE447964T1 true ATE447964T1 (de) 2009-11-15

Family

ID=27355973

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00925845T ATE447964T1 (de) 1999-05-03 2000-05-03 Eine pharmazeutische formulierung, enthaltend einen inhibitor der carboxypeptidase a und einen thrombin-inhibitor

Country Status (26)

Country Link
US (1) US6974800B1 (de)
EP (1) EP1181048B1 (de)
JP (1) JP2002543148A (de)
KR (1) KR100725206B1 (de)
CN (1) CN100518820C (de)
AR (1) AR023819A1 (de)
AT (1) ATE447964T1 (de)
AU (1) AU763772B2 (de)
BR (1) BR0010255A (de)
CA (1) CA2371217A1 (de)
CZ (1) CZ20013932A3 (de)
DE (1) DE60043297D1 (de)
EE (1) EE200100578A (de)
ES (1) ES2335383T3 (de)
HK (1) HK1042442B (de)
HU (1) HUP0201615A3 (de)
IL (1) IL145951A0 (de)
IS (1) IS6140A (de)
MX (1) MXPA01011044A (de)
MY (1) MY126962A (de)
NO (1) NO20015308L (de)
NZ (1) NZ515063A (de)
SK (1) SK15652001A3 (de)
TR (1) TR200103151T2 (de)
TW (1) TWI232106B (de)
WO (1) WO2000066152A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9901572D0 (sv) * 1999-05-03 1999-05-03 Astra Ab New compounds
CN1187360C (zh) 1999-09-14 2005-02-02 明治制果株式会社 有羧基肽酶b抑制活性的膦酸衍生物
SE0001803D0 (sv) 2000-05-16 2000-05-16 Astrazeneca Ab New compounds i
SE0103272D0 (sv) 2001-09-28 2001-09-28 Astrazeneca Ab Chemical compounds
US6713496B2 (en) 2002-01-22 2004-03-30 Pfizer Inc 3-(imidazolyl)-2-alkoxypropanoic acids
CA2472239A1 (en) 2002-01-22 2003-07-31 Pfizer Inc. 3-(imidazolyl)-2-aminopropanoic acids for use as tafi-a inhibitors for the treatment of thrombotic diseases
BR0308601A (pt) 2002-03-21 2007-01-09 Schering Ag inibidores de carboxipeptidase b de plasma
ZA200800251B (en) * 2005-06-24 2009-04-29 Drugrecure Aps Airway administration of tissue factor pathway inhibitor in inflammatory conditions affecting the respiratory track
WO2014198620A1 (en) 2013-06-10 2014-12-18 Sanofi Macrocyclic urea derivatives as inhibitors of tafia, their preparation and their use as pharmaceuticals

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3091569A (en) 1960-08-26 1963-05-28 Mead Johnson & Co Mucolytic-nu-acylated sulfhydryl compositions and process for treating animal mucus
FR1393338A (fr) 1964-01-08 1965-03-26 Rech S Pharma Et Scient Nouveau dérivé de la cystéine et sa préparation
US3766206A (en) 1971-11-03 1973-10-16 Pfizer 18beta-glycyrrheting acid amides useful as antiulcer agents
FR2266502A1 (en) 1974-04-08 1975-10-31 Synpharm Sa N-(2-thenoyl)-cysteine and esters - with mucolytic activity, prepd. from cysteine (esters) and thenoyl chloride
US4113715A (en) 1977-01-17 1978-09-12 E. R. Squibb & Sons, Inc. Amino acid derivatives
US4177277A (en) 1977-01-17 1979-12-04 E. R. Squibb & Sons, Inc. Method for alleviating hypertension
JPS545949A (en) 1977-06-16 1979-01-17 Hisamitsu Pharmaceut Co Inc Novel cyclohexanecarboxylic acid and its derivatives
FR2430945A2 (fr) 1978-07-12 1980-02-08 Chauvin Blache Lab Nouveaux derives de la cysteine, leur procede de fabrication et leur application en therapeutique
US4708965A (en) 1985-09-16 1987-11-24 Morgan Lee R Method of treating herpes virus infections with N,N'-diacetylcystine and derivatives
DE3838467C2 (de) 1988-11-12 1998-12-10 Agfa Gevaert Ag Fotografisches Aufzeichnungsmaterial
US5206161A (en) * 1991-02-01 1993-04-27 Genentech, Inc. Human plasma carboxypeptidase B
IT1249650B (it) 1991-05-29 1995-03-09 Poli Ind Chimica Spa N-(5-tioxo-l-prolil)-l-cisteina e suoi derivati, loro preparazione ed impiego terapeutico
SE9103612D0 (sv) * 1991-12-04 1991-12-04 Astra Ab New peptide derivatives
SE9301916D0 (sv) * 1993-06-03 1993-06-03 Ab Astra New peptides derivatives
SE9404196D0 (sv) * 1994-12-02 1994-12-02 Astra Ab New antithrombotic formulation
KR0173034B1 (ko) 1995-04-28 1999-03-30 성재갑 선택적 트롬빈 억제제
GB9525620D0 (en) * 1995-12-15 1996-02-14 Glaxo Group Ltd Chemical compounds
US5859271A (en) * 1996-04-15 1999-01-12 Virginia Commonwealth University Cytoprotective compounds
US6126939A (en) * 1996-09-03 2000-10-03 Yeda Research And Development Co. Ltd. Anti-inflammatory dipeptide and pharmaceutical composition thereof
US5993815A (en) * 1996-11-08 1999-11-30 University Of Vermont Methods and compositions for inhibiting the activation of thrombin-activatable fibrinolysis inhibitor (TAFI)
US6117911A (en) * 1997-04-11 2000-09-12 Neorx Corporation Compounds and therapies for the prevention of vascular and non-vascular pathologies

Also Published As

Publication number Publication date
EP1181048A1 (de) 2002-02-27
NO20015308L (no) 2001-12-03
KR100725206B1 (ko) 2007-06-07
HK1042442B (zh) 2010-04-09
HK1042442A1 (en) 2002-08-16
IS6140A (is) 2001-11-01
EE200100578A (et) 2003-02-17
AU763772B2 (en) 2003-07-31
MY126962A (en) 2006-11-30
DE60043297D1 (de) 2009-12-24
CZ20013932A3 (cs) 2002-04-17
JP2002543148A (ja) 2002-12-17
EP1181048B1 (de) 2009-11-11
NZ515063A (en) 2003-08-29
SK15652001A3 (sk) 2002-07-02
ES2335383T3 (es) 2010-03-26
WO2000066152A1 (en) 2000-11-09
AR023819A1 (es) 2002-09-04
CA2371217A1 (en) 2000-11-02
TR200103151T2 (tr) 2002-04-22
AU4447200A (en) 2000-11-17
KR20020003386A (ko) 2002-01-12
MXPA01011044A (es) 2002-06-04
US6974800B1 (en) 2005-12-13
BR0010255A (pt) 2002-02-13
PL356119A1 (en) 2004-06-14
TWI232106B (en) 2005-05-11
HUP0201615A3 (en) 2006-07-28
CN1350463A (zh) 2002-05-22
NO20015308D0 (no) 2001-10-30
CN100518820C (zh) 2009-07-29
IL145951A0 (en) 2002-07-25
HUP0201615A2 (en) 2002-09-28

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties