ATE446089T1 - 2-benzoyl-imidazopyridin-derivate, herstellungsverfahren und ihre verwendung für therapeutika - Google Patents
2-benzoyl-imidazopyridin-derivate, herstellungsverfahren und ihre verwendung für therapeutikaInfo
- Publication number
- ATE446089T1 ATE446089T1 AT07803831T AT07803831T ATE446089T1 AT E446089 T1 ATE446089 T1 AT E446089T1 AT 07803831 T AT07803831 T AT 07803831T AT 07803831 T AT07803831 T AT 07803831T AT E446089 T1 ATE446089 T1 AT E446089T1
- Authority
- AT
- Austria
- Prior art keywords
- preparation
- therapeutics
- benzoyl
- imidazopyridine derivatives
- imidazopyridine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Epidemiology (AREA)
- Addiction (AREA)
- Hospice & Palliative Care (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0606010A FR2903105A1 (fr) | 2006-07-03 | 2006-07-03 | Derives de 2-benzoyl-imidazopyridines, leur preparation et leur application en therapeutique |
PCT/FR2007/001123 WO2008003854A2 (fr) | 2006-07-03 | 2007-07-03 | Derives de 2-benzoyl-imidazopyridines, leur preparation et leur application en therapeutique |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE446089T1 true ATE446089T1 (de) | 2009-11-15 |
Family
ID=37661856
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT07803831T ATE446089T1 (de) | 2006-07-03 | 2007-07-03 | 2-benzoyl-imidazopyridin-derivate, herstellungsverfahren und ihre verwendung für therapeutika |
Country Status (21)
Country | Link |
---|---|
US (1) | US7902219B2 (de) |
EP (1) | EP2040703B1 (de) |
JP (1) | JP2009541469A (de) |
KR (1) | KR20090024775A (de) |
CN (1) | CN101484163A (de) |
AT (1) | ATE446089T1 (de) |
AU (1) | AU2007271082A1 (de) |
BR (1) | BRPI0713260A2 (de) |
CA (1) | CA2656045A1 (de) |
CY (1) | CY1109743T1 (de) |
DE (1) | DE602007002915D1 (de) |
DK (1) | DK2040703T3 (de) |
ES (1) | ES2335323T3 (de) |
FR (1) | FR2903105A1 (de) |
IL (1) | IL195818A0 (de) |
MX (1) | MX2008016558A (de) |
PL (1) | PL2040703T3 (de) |
PT (1) | PT2040703E (de) |
RU (1) | RU2009103300A (de) |
SI (1) | SI2040703T1 (de) |
WO (1) | WO2008003854A2 (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2925905B1 (fr) * | 2008-01-02 | 2010-11-05 | Sanofi Aventis | DERIVES DE 2-BENZOYL-IMIDAZO°1,2-a!PYRIDINE, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE |
FR2925907B1 (fr) * | 2008-01-02 | 2010-10-15 | Sanofi Aventis | DERIVES DE 2-HETEROAROYL-IMIDAZO°1,2-a!PYRIDINE, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE |
FR2928923B1 (fr) * | 2008-03-21 | 2010-04-23 | Sanofi Aventis | Derives polysubstitues de 2-heteroaryl-6-phenyl-imidazo °1,2-a!pyridines, leur preparation et leur application en therapeutiques |
FR2928922B1 (fr) * | 2008-03-21 | 2010-04-23 | Sanofi Aventis | Derives de 2-aryl-6-phenyl-imidazo°1,2-a!pyridines polysubstitues, leur preparation et leur application en therapeutique |
FR2928924B1 (fr) | 2008-03-21 | 2010-04-23 | Sanofi Aventis | Derives polysubstitues de 6-heteroaryle-imidazo°1,2-a! pyridines, leur preparation et leur application en therapeutique |
FR2928921B1 (fr) * | 2008-03-21 | 2010-04-23 | Sanofi Aventis | Derives polysubstitues de 2-aryl-6-phenyl-imidazo°1,2-a!pyridines, leur preparation et leur application en therapeutique |
FR2933609B1 (fr) | 2008-07-10 | 2010-08-27 | Fournier Lab Sa | Utilisation de derives d'indole comme activateurs de nurr-1, pour le traitement de la maladie de parkinson. |
FR2950053B1 (fr) | 2009-09-11 | 2014-08-01 | Fournier Lab Sa | Utilisation de derives d'indole benzoique comme activateurs de nurr-1, pour le traitement de la maladie de parkinson |
FR2955110A1 (fr) | 2010-01-08 | 2011-07-15 | Fournier Lab Sa | Nouveaux derives de type pyrrolopyridine benzoique |
CN103772381B (zh) * | 2013-09-16 | 2015-11-25 | 广东华南新药创制中心 | 一种四稠环喹啉类化合物及其制备方法 |
WO2021204626A1 (en) | 2020-04-06 | 2021-10-14 | Almirall, S.A. | Aryl and heteroaryl-carboxamide substituted heteroaryl compounds as tyk2 inhibitors |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2638161B1 (fr) * | 1988-10-24 | 1991-01-11 | Centre Nat Rech Scient | Nouvelles benzoyl-2 imidazo (1,2-a) pyridines et leurs sels, leur procede de preparation, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant |
AU2001249672A1 (en) * | 2000-03-31 | 2001-10-15 | Ortho-Mcneil Pharmaceutical, Inc. | Method for using 2- or 3-aryl substituted imidazo(1,2-a) pyridines as h3 antagonists |
DE10117184A1 (de) | 2001-04-05 | 2002-10-17 | Gruenenthal Gmbh | Substituierte Imidazol[1,2-a]-pyridin-3-yl-amid- und -aminverbindungen |
ES2421511T3 (es) * | 2001-12-21 | 2013-09-03 | X Ceptor Therapeutics Inc | Moduladores de LXR |
GB0303503D0 (en) | 2003-02-14 | 2003-03-19 | Novartis Ag | Organic compounds |
EP1615636A1 (de) * | 2003-04-10 | 2006-01-18 | Pfizer Inc. | Bicyclische verbindungen als nr2b-rezeptor-antagonisten |
AR045944A1 (es) | 2003-09-24 | 2005-11-16 | Novartis Ag | Derivados de isoquinolina 1.4-disustituidas |
WO2005044793A2 (en) * | 2003-10-31 | 2005-05-19 | Takeda Pharmaceutical Company Limited | Nitrogen-containing fused heterocyclic compounds |
EP1684762A4 (de) | 2003-11-13 | 2009-06-17 | Ambit Biosciences Corp | Harnstoff-derivate als kinase-modulatoren |
AU2005278959A1 (en) | 2004-08-31 | 2006-03-09 | Astrazeneca Ab | Quinazolinone derivatives and their use as B-Raf inhibitors |
TW200635899A (en) | 2004-12-22 | 2006-10-16 | Astrazeneca Ab | Chemical compounds |
EP1831198B1 (de) | 2004-12-22 | 2009-04-08 | AstraZeneca AB | Pyridincarbonsäureamidderivate zur verwendung als antikrebsmittel |
-
2006
- 2006-07-03 FR FR0606010A patent/FR2903105A1/fr active Pending
-
2007
- 2007-07-03 KR KR1020097000049A patent/KR20090024775A/ko not_active Application Discontinuation
- 2007-07-03 WO PCT/FR2007/001123 patent/WO2008003854A2/fr active Application Filing
- 2007-07-03 AU AU2007271082A patent/AU2007271082A1/en not_active Abandoned
- 2007-07-03 RU RU2009103300/15A patent/RU2009103300A/ru not_active Application Discontinuation
- 2007-07-03 AT AT07803831T patent/ATE446089T1/de active
- 2007-07-03 PL PL07803831T patent/PL2040703T3/pl unknown
- 2007-07-03 EP EP07803831A patent/EP2040703B1/de not_active Not-in-force
- 2007-07-03 CN CNA2007800252640A patent/CN101484163A/zh active Pending
- 2007-07-03 JP JP2009517330A patent/JP2009541469A/ja not_active Withdrawn
- 2007-07-03 ES ES07803831T patent/ES2335323T3/es active Active
- 2007-07-03 SI SI200730133T patent/SI2040703T1/sl unknown
- 2007-07-03 DK DK07803831.2T patent/DK2040703T3/da active
- 2007-07-03 DE DE602007002915T patent/DE602007002915D1/de active Active
- 2007-07-03 BR BRPI0713260-3A patent/BRPI0713260A2/pt not_active IP Right Cessation
- 2007-07-03 PT PT07803831T patent/PT2040703E/pt unknown
- 2007-07-03 CA CA002656045A patent/CA2656045A1/fr not_active Abandoned
- 2007-07-03 MX MX2008016558A patent/MX2008016558A/es unknown
-
2008
- 2008-12-09 IL IL195818A patent/IL195818A0/en unknown
- 2008-12-17 US US12/336,989 patent/US7902219B2/en not_active Expired - Fee Related
-
2010
- 2010-01-20 CY CY20101100057T patent/CY1109743T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
BRPI0713260A2 (pt) | 2012-04-03 |
PL2040703T3 (pl) | 2010-03-31 |
CY1109743T1 (el) | 2014-09-10 |
KR20090024775A (ko) | 2009-03-09 |
US7902219B2 (en) | 2011-03-08 |
AU2007271082A1 (en) | 2008-01-10 |
RU2009103300A (ru) | 2010-08-10 |
DE602007002915D1 (de) | 2009-12-03 |
CA2656045A1 (fr) | 2008-01-10 |
WO2008003854A2 (fr) | 2008-01-10 |
CN101484163A (zh) | 2009-07-15 |
US20090143420A1 (en) | 2009-06-04 |
IL195818A0 (en) | 2009-09-01 |
DK2040703T3 (da) | 2010-03-08 |
JP2009541469A (ja) | 2009-11-26 |
PT2040703E (pt) | 2010-01-19 |
SI2040703T1 (sl) | 2010-02-26 |
ES2335323T3 (es) | 2010-03-24 |
WO2008003854A3 (fr) | 2008-03-06 |
FR2903105A1 (fr) | 2008-01-04 |
EP2040703A2 (de) | 2009-04-01 |
EP2040703B1 (de) | 2009-10-21 |
MX2008016558A (es) | 2009-05-20 |
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