ATE444096T1 - Verfahren zur herstellung von geformten mikronadeln - Google Patents
Verfahren zur herstellung von geformten mikronadelnInfo
- Publication number
- ATE444096T1 ATE444096T1 AT05776430T AT05776430T ATE444096T1 AT E444096 T1 ATE444096 T1 AT E444096T1 AT 05776430 T AT05776430 T AT 05776430T AT 05776430 T AT05776430 T AT 05776430T AT E444096 T1 ATE444096 T1 AT E444096T1
- Authority
- AT
- Austria
- Prior art keywords
- projections
- micro
- mold
- molds
- positive
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C45/00—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor
- B29C45/17—Component parts, details or accessories; Auxiliary operations
- B29C45/26—Moulds
- B29C45/2628—Moulds with mould parts forming holes in or through the moulded article, e.g. for bearing cages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B81—MICROSTRUCTURAL TECHNOLOGY
- B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
- B81C99/00—Subject matter not provided for in other groups of this subclass
- B81C99/0075—Manufacture of substrate-free structures
- B81C99/0085—Manufacture of substrate-free structures using moulds and master templates, e.g. for hot-embossing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0053—Methods for producing microneedles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C45/00—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor
- B29C2045/0094—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor injection moulding of small-sized articles, e.g. microarticles, ultra thin articles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B81—MICROSTRUCTURAL TECHNOLOGY
- B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
- B81B2201/00—Specific applications of microelectromechanical systems
- B81B2201/05—Microfluidics
- B81B2201/055—Microneedles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B81—MICROSTRUCTURAL TECHNOLOGY
- B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
- B81B2203/00—Basic microelectromechanical structures
- B81B2203/03—Static structures
- B81B2203/0361—Tips, pillars
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B81—MICROSTRUCTURAL TECHNOLOGY
- B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
- B81C2201/00—Manufacture or treatment of microstructural devices or systems
- B81C2201/03—Processes for manufacturing substrate-free structures
- B81C2201/034—Moulding
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0402100A SE0402100D0 (sv) | 2004-08-30 | 2004-08-30 | Molded micro-needles |
PCT/SE2005/001260 WO2006025786A1 (en) | 2004-08-30 | 2005-08-30 | Molded micro-needles |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE444096T1 true ATE444096T1 (de) | 2009-10-15 |
Family
ID=33096051
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT05776430T ATE444096T1 (de) | 2004-08-30 | 2005-08-30 | Verfahren zur herstellung von geformten mikronadeln |
Country Status (7)
Country | Link |
---|---|
US (1) | US7981346B2 (de) |
EP (1) | EP1796778B1 (de) |
JP (1) | JP2008511382A (de) |
AT (1) | ATE444096T1 (de) |
DE (1) | DE602005016951D1 (de) |
SE (1) | SE0402100D0 (de) |
WO (1) | WO2006025786A1 (de) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100540086C (zh) * | 2004-03-12 | 2009-09-16 | 新加坡科技研究局 | 用来制造侧开口微型针的方法及模具 |
GB0616411D0 (en) * | 2006-08-18 | 2006-09-27 | Renishaw Plc | Neurosurgical instruments |
JP2010502267A (ja) * | 2006-08-28 | 2010-01-28 | エージェンシー・フォー・サイエンス・テクノロジー・アンド・リサーチ | マイクロニードルおよびマイクロニードルの製造方法 |
WO2008036043A1 (en) * | 2006-09-18 | 2008-03-27 | Agency For Science, Technology And Research | Needle structures and methods for fabricating needle structures |
US7713196B2 (en) * | 2007-03-09 | 2010-05-11 | Nellcor Puritan Bennett Llc | Method for evaluating skin hydration and fluid compartmentalization |
DE102008052749B4 (de) * | 2008-10-22 | 2012-01-12 | Hahn-Schickard-Gesellschaft für angewandte Forschung e.V. | Nadel, Nadelanordnung, Spritzgussform und Verfahren zum Herstellen |
FI20095433A0 (fi) * | 2009-04-20 | 2009-04-20 | Valtion Teknillinen | Mikroneula |
EP2275164A1 (de) * | 2009-07-15 | 2011-01-19 | Debiotech S.A. | Mikronadeln mit mehreren Kanälen |
AU2011246879C1 (en) | 2010-04-28 | 2016-03-24 | Sorrento Therapeutics, Inc. | Device for delivery of rheumatoid arthritis medication |
AU2011311255B2 (en) | 2010-04-28 | 2015-10-08 | Sorrento Therapeutics, Inc. | Method for increasing permeability of an epithelial barrier |
AU2011288209C1 (en) * | 2010-04-28 | 2016-03-24 | Kimberly-Clark Worldwide, Inc. | Injection molded microneedle array and method for forming the microneedle array |
CN102985131B (zh) | 2010-04-28 | 2016-06-29 | 金伯利-克拉克环球有限公司 | 用于递送siRNA的医疗装置 |
US20170246439A9 (en) | 2011-10-27 | 2017-08-31 | Kimberly-Clark Worldwide, Inc. | Increased Bioavailability of Transdermally Delivered Agents |
WO2013061208A1 (en) | 2011-10-27 | 2013-05-02 | Kimberly-Clark Worldwide, Inc. | Transdermal delivery of high viscosity bioactive agents |
BR112014009712A2 (pt) | 2011-10-27 | 2017-04-18 | Kimberly Clark Co | dispositivos implantáveis para a administração de agentes bioativos |
JP6155539B2 (ja) * | 2011-12-02 | 2017-07-05 | 凸版印刷株式会社 | 針状体の製造方法および針状体の転写版 |
JP5856475B2 (ja) * | 2011-12-28 | 2016-02-09 | Asti株式会社 | マイクロニードルの製造方法 |
EP2662110A1 (de) | 2012-05-10 | 2013-11-13 | Debiotech S.A. | Vorrichtung und Methode für das Einsetzen von Nadeln |
US10232157B2 (en) | 2013-07-16 | 2019-03-19 | 3M Innovative Properties Company | Hollow microneedle with beveled tip |
WO2015009531A1 (en) | 2013-07-16 | 2015-01-22 | 3M Innovative Properties Company | Article comprising a microneedle |
US10384047B2 (en) | 2013-07-16 | 2019-08-20 | 3M Innovative Properties Company | Hollow microneedle with bevel opening |
EP3021931B1 (de) | 2013-07-16 | 2021-09-01 | Kindeva Drug Delivery L.P. | Hohlmikronadelfeldartikel |
KR102012241B1 (ko) * | 2017-08-30 | 2019-08-21 | 한국기계연구원 | 마이크로니들 구조체, 이의 제조방법 및 장치 |
KR102240614B1 (ko) * | 2018-06-22 | 2021-04-16 | 주식회사 에스엔비아 | 화살촉 형상의 마이크로니들 |
WO2020256198A1 (ko) * | 2019-06-21 | 2020-12-24 | 주식회사 에스엔비아 | 화살촉 형상의 마이크로니들 및 그 제조장치와 제조방법 |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4838877A (en) | 1985-08-06 | 1989-06-13 | Massau Bruce A | Polymeric hypodermic device |
US6573256B2 (en) | 1996-12-30 | 2003-06-03 | Bone Care International, Inc. | Method of inhibiting angiogenesis using active vitamin D analogues |
WO1999064580A1 (en) * | 1998-06-10 | 1999-12-16 | Georgia Tech Research Corporation | Microneedle devices and methods of manufacture and use thereof |
US6719719B2 (en) | 1998-11-13 | 2004-04-13 | Elan Pharma International Limited | Spike for liquid transfer device, liquid transfer device including spike, and method of transferring liquids using the same |
JP2002532165A (ja) | 1998-12-18 | 2002-10-02 | メドトロニック ミニメド インコーポレイテッド | 医療装置と共に使われる、微小突刺し部材を備える挿入セット及びそのような挿入セットの使用方法 |
US6743211B1 (en) * | 1999-11-23 | 2004-06-01 | Georgia Tech Research Corporation | Devices and methods for enhanced microneedle penetration of biological barriers |
US20040039342A1 (en) * | 2000-06-08 | 2004-02-26 | Jonathan Eppstein | Transdermal integrated actuator device, methods of making and using same |
US6312612B1 (en) * | 1999-06-09 | 2001-11-06 | The Procter & Gamble Company | Apparatus and method for manufacturing an intracutaneous microneedle array |
US6379324B1 (en) * | 1999-06-09 | 2002-04-30 | The Procter & Gamble Company | Intracutaneous microneedle array apparatus |
US6629949B1 (en) | 2000-05-08 | 2003-10-07 | Sterling Medivations, Inc. | Micro infusion drug delivery device |
US9302903B2 (en) * | 2000-12-14 | 2016-04-05 | Georgia Tech Research Corporation | Microneedle devices and production thereof |
US6767341B2 (en) * | 2001-06-13 | 2004-07-27 | Abbott Laboratories | Microneedles for minimally invasive drug delivery |
US6749792B2 (en) * | 2001-07-09 | 2004-06-15 | Lifescan, Inc. | Micro-needles and methods of manufacture and use thereof |
SE0102736D0 (sv) * | 2001-08-14 | 2001-08-14 | Patrick Griss | Side opened out-of-plane microneedles for microfluidic transdermal interfacing and fabrication process of side opened out-of-plane microneedles |
US6881203B2 (en) * | 2001-09-05 | 2005-04-19 | 3M Innovative Properties Company | Microneedle arrays and methods of manufacturing the same |
AU2002327675A1 (en) * | 2001-09-19 | 2003-04-01 | Biovalve Technologies, Inc. | Microneedles, microneedle arrays, and systems and methods relating to same |
CA2500452A1 (en) * | 2001-09-28 | 2003-04-03 | Biovalve Technologies, Inc. | Switchable microneedle arrays and systems and methods relating to same |
ATE420676T1 (de) * | 2001-10-29 | 2009-01-15 | Becton Dickinson Co | Vorrichtung für die abgabe einer substanz |
EP1485317A2 (de) * | 2001-11-30 | 2004-12-15 | Alza Corporation | Verfahren und vorrichtungen zur herstellung von mikroprojektoranordnungen |
US6899838B2 (en) * | 2002-07-12 | 2005-05-31 | Becton, Dickinson And Company | Method of forming a mold and molding a micro-device |
WO2004033021A1 (en) * | 2002-10-07 | 2004-04-22 | Biovalve Technologies, Inc. | Microneedle array patch |
US7578954B2 (en) * | 2003-02-24 | 2009-08-25 | Corium International, Inc. | Method for manufacturing microstructures having multiple microelements with through-holes |
WO2005004729A1 (en) * | 2003-06-30 | 2005-01-20 | Alza Corporation | Method for coating skin piercing microprojections |
-
2004
- 2004-08-30 SE SE0402100A patent/SE0402100D0/xx unknown
-
2005
- 2005-08-30 US US11/661,113 patent/US7981346B2/en not_active Expired - Fee Related
- 2005-08-30 EP EP05776430A patent/EP1796778B1/de not_active Not-in-force
- 2005-08-30 WO PCT/SE2005/001260 patent/WO2006025786A1/en active Application Filing
- 2005-08-30 DE DE602005016951T patent/DE602005016951D1/de active Active
- 2005-08-30 JP JP2007529775A patent/JP2008511382A/ja active Pending
- 2005-08-30 AT AT05776430T patent/ATE444096T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
SE0402100D0 (sv) | 2004-08-30 |
WO2006025786A1 (en) | 2006-03-09 |
EP1796778A1 (de) | 2007-06-20 |
DE602005016951D1 (de) | 2009-11-12 |
US7981346B2 (en) | 2011-07-19 |
US20070255205A1 (en) | 2007-11-01 |
JP2008511382A (ja) | 2008-04-17 |
EP1796778B1 (de) | 2009-09-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE444096T1 (de) | Verfahren zur herstellung von geformten mikronadeln | |
BRPI0509773A (pt) | preformas, garrafas e método para fabricar as preformas e as garrafas | |
TW200720053A (en) | Manufacturing process of suction cup, suction cup and in-vehicle instrument | |
WO2012106512A3 (en) | Nozzle and method of making same | |
DE602008005989D1 (de) | Formelement zum Ausformen dreidimensionaler Produkte, System und Verfahren zum Herstellen eines Formelements | |
BRPI0515214A (pt) | molde para moldagem por injeção, processo para fabricar uma peça de matéria plástica e peça de matéria plástica | |
ATE496754T1 (de) | Verfahren zur herstellung eines kunststoffhohlkörpers aus einem vorformling | |
EP2020283A4 (de) | Formwerkzeug zum formen von thermoplastischem harz, hohlraumformwerkzeug und verfahren zur herstellung des hohlraumformwerkzeugs | |
DE602007004310D1 (de) | Spritzvorrichtung und entsprechendes verfahren zur herstellung einer dünnen wandkomponente, kern und vorformling | |
ATE301037T1 (de) | Verfahren zur herstellung eines kunststoff- kraftstofftanks | |
WO2012000621A3 (de) | Verfahren zur herstellung eines kunststoffartikels sowie blasformwerkzeug zur durchführung des verfahrens | |
BRPI0509395A (pt) | conjunto de preformado, conjunto de recipiente, e método de fabricação | |
PL1888316T3 (pl) | Sposób kontroli procesu wtryskiwania we wtryskarce | |
WO2011061593A8 (en) | Method for manufacturing monolithic hollow bodies by means of a casting or injection molding process | |
WO2006039309A3 (en) | A molded, plastic container and a method for making the same | |
WO2005084487A3 (en) | Injection moulding process | |
DE602004029427D1 (de) | Blasformverfahren | |
ATE355952T1 (de) | Verfahren zum herstellen von hinterspritzten kunststoffformteilen | |
CN104972599A (zh) | 一种灯罩注塑工艺 | |
MX351552B (es) | Método para calibrar una abertura de vertido de un contenedor de plástico producido mediante el proceso de moldeado por soplado de extrusión. | |
WO2010060919A3 (de) | Vorrichtung und verfahren zum herstellen von kunststoffbehältnissen und nach diesem verfahren hergestelltes kunststoffbehältnis | |
SE0200195L (sv) | Förfarande och anordning för framställning av plastdetaljer | |
DE502004011314D1 (de) | Formwerkzeug zur herstellung von formschaumkörpern | |
CN207657105U (zh) | 微发泡注塑模具排气结构 | |
CN104015306B (zh) | Pcr板注塑成型模具及其方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |