ATE430760T1 - Dipeptide und tripeptide mit anti- inflammatorischer wirkung - Google Patents

Dipeptide und tripeptide mit anti- inflammatorischer wirkung

Info

Publication number
ATE430760T1
ATE430760T1 AT03701387T AT03701387T ATE430760T1 AT E430760 T1 ATE430760 T1 AT E430760T1 AT 03701387 T AT03701387 T AT 03701387T AT 03701387 T AT03701387 T AT 03701387T AT E430760 T1 ATE430760 T1 AT E430760T1
Authority
AT
Austria
Prior art keywords
amino
acid
tripeptides
dipeptides
inflammatory effect
Prior art date
Application number
AT03701387T
Other languages
English (en)
Inventor
Ronald Mathison
Original Assignee
Salpep Biotechnology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Salpep Biotechnology Inc filed Critical Salpep Biotechnology Inc
Application granted granted Critical
Publication of ATE430760T1 publication Critical patent/ATE430760T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/0606—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/081—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
AT03701387T 2002-02-04 2003-02-04 Dipeptide und tripeptide mit anti- inflammatorischer wirkung ATE430760T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35323102P 2002-02-04 2002-02-04
PCT/CA2003/000147 WO2003066670A2 (en) 2002-02-04 2003-02-04 Dipeptides and tripeptides with anti-inflammatory activity

Publications (1)

Publication Number Publication Date
ATE430760T1 true ATE430760T1 (de) 2009-05-15

Family

ID=27734285

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03701387T ATE430760T1 (de) 2002-02-04 2003-02-04 Dipeptide und tripeptide mit anti- inflammatorischer wirkung

Country Status (9)

Country Link
US (2) US7153835B2 (de)
EP (2) EP2072524A3 (de)
AT (1) ATE430760T1 (de)
AU (1) AU2003203082A1 (de)
CA (1) CA2475097C (de)
DE (1) DE60327512D1 (de)
DK (1) DK1474439T3 (de)
ES (1) ES2325251T3 (de)
WO (1) WO2003066670A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1930183B (zh) * 2003-08-13 2010-12-29 康哲医药研究(深圳)有限公司 包含苯丙氨酰-谷氨酸及苯丙氨酰-谷氨酰-谷氨酸的生物活性肽
US8431535B2 (en) * 2004-09-10 2013-04-30 Hoiberg A/S Methods for treating local tracheal, bronchial or alveolar bleeding or hemoptysis
US10314917B2 (en) 2013-03-15 2019-06-11 The Brigham And Women's Hospital, Inc. Targeted polymeric inflammation-resolving nanoparticles
WO2019054809A2 (ko) * 2017-09-15 2019-03-21 주식회사 바이오펩 자가면역질환 및 골질환 치료제로서의 펩타이드의 용도
AU2018333776B2 (en) 2017-09-15 2022-07-07 Kine Sciences Co., Ltd. Use of peptides as therapeutic agent for autoimmune diseases and bone diseases
KR102166928B1 (ko) * 2017-09-15 2020-10-19 주식회사 카인사이언스 골질환 치료제로서의 펩타이드의 용도
KR102166927B1 (ko) * 2017-09-15 2020-10-19 주식회사 카인사이언스 자가면역질환 치료제로서의 펩타이드의 용도

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4012367A (en) * 1976-02-05 1977-03-15 G. D. Searle & Co. Anti-ulcer polypeptides containing L-aspartic acid and intermediates thereto
US4880779A (en) * 1987-07-31 1989-11-14 Research Corporation Technologies, Inc. Method of prevention or treatment of AIDS by inhibition of human immunodeficiency virus
CZ203693A3 (en) * 1991-04-01 1994-07-13 Cortech Bradykinin antagonists
US5837686A (en) * 1991-11-25 1998-11-17 Peptide Therapeutics Limited Peptides and antibodies for treatment of rheumatoid arthritis
NZ277206A (en) * 1993-12-06 1997-11-24 Cytel Corp Peptide inhibiting binding of vlh-4 receptor expressed in inflammatory leukocytes and fibronectin cs-1 peptide expressed on endothelial cells involved in inflammatory disease states
GB9617021D0 (en) 1996-08-13 1996-09-25 Salpep Biotechnology Inc Novel peptides for treatment of inflammation and shock
US6413530B1 (en) 1999-04-21 2002-07-02 University Of Florida Research Foundation, Inc. Pesticidal peptides
US6586403B1 (en) * 2000-07-20 2003-07-01 Salpep Biotechnology, Inc. Treating allergic reactions and inflammatory responses with tri-and dipeptides

Also Published As

Publication number Publication date
CA2475097C (en) 2012-05-08
DK1474439T3 (da) 2009-08-03
US7153835B2 (en) 2006-12-26
US20070054865A1 (en) 2007-03-08
DE60327512D1 (de) 2009-06-18
WO2003066670A2 (en) 2003-08-14
AU2003203082A1 (en) 2003-09-02
EP1474439A2 (de) 2004-11-10
EP2072524A3 (de) 2009-09-09
AU2003203082A8 (en) 2003-09-02
EP2072524A2 (de) 2009-06-24
WO2003066670A3 (en) 2004-07-15
US20030195141A1 (en) 2003-10-16
EP1474439B1 (de) 2009-05-06
CA2475097A1 (en) 2003-08-14
US7833986B2 (en) 2010-11-16
ES2325251T3 (es) 2009-08-31

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Legal Events

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