DK1474439T3 - Dipeptider og tripeptider med anti-inflammatorisk virkning - Google Patents

Dipeptider og tripeptider med anti-inflammatorisk virkning

Info

Publication number
DK1474439T3
DK1474439T3 DK03701387T DK03701387T DK1474439T3 DK 1474439 T3 DK1474439 T3 DK 1474439T3 DK 03701387 T DK03701387 T DK 03701387T DK 03701387 T DK03701387 T DK 03701387T DK 1474439 T3 DK1474439 T3 DK 1474439T3
Authority
DK
Denmark
Prior art keywords
amino
acid
tripeptides
dipeptides
inflammatory action
Prior art date
Application number
DK03701387T
Other languages
English (en)
Inventor
Ronald Mathison
Original Assignee
Salpep Biotechnology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Salpep Biotechnology Inc filed Critical Salpep Biotechnology Inc
Application granted granted Critical
Publication of DK1474439T3 publication Critical patent/DK1474439T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/0606—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/081—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK03701387T 2002-02-04 2003-02-04 Dipeptider og tripeptider med anti-inflammatorisk virkning DK1474439T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35323102P 2002-02-04 2002-02-04
PCT/CA2003/000147 WO2003066670A2 (en) 2002-02-04 2003-02-04 Dipeptides and tripeptides with anti-inflammatory activity

Publications (1)

Publication Number Publication Date
DK1474439T3 true DK1474439T3 (da) 2009-08-03

Family

ID=27734285

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03701387T DK1474439T3 (da) 2002-02-04 2003-02-04 Dipeptider og tripeptider med anti-inflammatorisk virkning

Country Status (9)

Country Link
US (2) US7153835B2 (da)
EP (2) EP2072524A3 (da)
AT (1) ATE430760T1 (da)
AU (1) AU2003203082A1 (da)
CA (1) CA2475097C (da)
DE (1) DE60327512D1 (da)
DK (1) DK1474439T3 (da)
ES (1) ES2325251T3 (da)
WO (1) WO2003066670A2 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1930183B (zh) * 2003-08-13 2010-12-29 康哲医药研究(深圳)有限公司 包含苯丙氨酰-谷氨酸及苯丙氨酰-谷氨酰-谷氨酸的生物活性肽
EP1791555B1 (en) * 2004-09-10 2013-03-13 Pharmaorigin ApS Methods for treating local tracheal, bronchial or alveolar bleeding or hemoptysis
WO2014145749A1 (en) 2013-03-15 2014-09-18 The Brigham And Women's Hospital, Inc. Targeted polymeric inflammation-resolving nanoparticles
KR102166928B1 (ko) * 2017-09-15 2020-10-19 주식회사 카인사이언스 골질환 치료제로서의 펩타이드의 용도
KR102166927B1 (ko) * 2017-09-15 2020-10-19 주식회사 카인사이언스 자가면역질환 치료제로서의 펩타이드의 용도
WO2019054809A2 (ko) * 2017-09-15 2019-03-21 주식회사 바이오펩 자가면역질환 및 골질환 치료제로서의 펩타이드의 용도
JP2020533375A (ja) 2017-09-15 2020-11-19 カイン サイエンス シーオー., エルティーディー.KINE SCIENCES Co., Ltd. 自己免疫疾患および骨疾患の治療剤としてのペプチドの用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4012367A (en) * 1976-02-05 1977-03-15 G. D. Searle & Co. Anti-ulcer polypeptides containing L-aspartic acid and intermediates thereto
US4880779A (en) 1987-07-31 1989-11-14 Research Corporation Technologies, Inc. Method of prevention or treatment of AIDS by inhibition of human immunodeficiency virus
WO1992017201A1 (en) * 1991-04-01 1992-10-15 Cortech, Inc. Bradykinin antagonists
US5837686A (en) * 1991-11-25 1998-11-17 Peptide Therapeutics Limited Peptides and antibodies for treatment of rheumatoid arthritis
NZ277206A (en) 1993-12-06 1997-11-24 Cytel Corp Peptide inhibiting binding of vlh-4 receptor expressed in inflammatory leukocytes and fibronectin cs-1 peptide expressed on endothelial cells involved in inflammatory disease states
GB9617021D0 (en) 1996-08-13 1996-09-25 Salpep Biotechnology Inc Novel peptides for treatment of inflammation and shock
US6413530B1 (en) 1999-04-21 2002-07-02 University Of Florida Research Foundation, Inc. Pesticidal peptides
US6586403B1 (en) * 2000-07-20 2003-07-01 Salpep Biotechnology, Inc. Treating allergic reactions and inflammatory responses with tri-and dipeptides

Also Published As

Publication number Publication date
EP1474439B1 (en) 2009-05-06
ES2325251T3 (es) 2009-08-31
EP2072524A2 (en) 2009-06-24
EP1474439A2 (en) 2004-11-10
AU2003203082A1 (en) 2003-09-02
CA2475097A1 (en) 2003-08-14
CA2475097C (en) 2012-05-08
US7153835B2 (en) 2006-12-26
WO2003066670A2 (en) 2003-08-14
US20030195141A1 (en) 2003-10-16
ATE430760T1 (de) 2009-05-15
US20070054865A1 (en) 2007-03-08
WO2003066670A3 (en) 2004-07-15
DE60327512D1 (de) 2009-06-18
AU2003203082A8 (en) 2003-09-02
US7833986B2 (en) 2010-11-16
EP2072524A3 (en) 2009-09-09

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