ATE429214T1 - Mikrokapseln für die verzögerte kontrollierte freisetzung von perindopril - Google Patents

Mikrokapseln für die verzögerte kontrollierte freisetzung von perindopril

Info

Publication number
ATE429214T1
ATE429214T1 AT03760778T AT03760778T ATE429214T1 AT E429214 T1 ATE429214 T1 AT E429214T1 AT 03760778 T AT03760778 T AT 03760778T AT 03760778 T AT03760778 T AT 03760778T AT E429214 T1 ATE429214 T1 AT E429214T1
Authority
AT
Austria
Prior art keywords
perindopril
sustained
controlled
release microcapsules
microcapsules
Prior art date
Application number
AT03760778T
Other languages
English (en)
Inventor
De Barochez Bruno Huet
Patrick Wutrich
Valerie Legrand
Catherine Castan
Remi Meyrueix
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Application granted granted Critical
Publication of ATE429214T1 publication Critical patent/ATE429214T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5015Organic compounds, e.g. fats, sugars
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/405Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5026Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
AT03760778T 2002-06-24 2003-06-24 Mikrokapseln für die verzögerte kontrollierte freisetzung von perindopril ATE429214T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0207778A FR2841140B1 (fr) 2002-06-24 2002-06-24 Microcapsules pour la liberation retardee et controlee du perindopril
PCT/FR2003/001931 WO2004000286A1 (fr) 2002-06-24 2003-06-24 Microcapsules pour la liberation retardee et controlee du perindopril

Publications (1)

Publication Number Publication Date
ATE429214T1 true ATE429214T1 (de) 2009-05-15

Family

ID=29719985

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03760778T ATE429214T1 (de) 2002-06-24 2003-06-24 Mikrokapseln für die verzögerte kontrollierte freisetzung von perindopril

Country Status (37)

Country Link
US (1) US20060165808A1 (de)
EP (1) EP1515704B1 (de)
JP (1) JP4723243B2 (de)
KR (1) KR100722082B1 (de)
CN (1) CN100345541C (de)
AP (1) AP2029A (de)
AR (1) AR040461A1 (de)
AT (1) ATE429214T1 (de)
AU (1) AU2003260620B2 (de)
BR (1) BR0312026A (de)
CA (1) CA2491172C (de)
CR (1) CR7648A (de)
CY (1) CY1109154T1 (de)
DE (1) DE60327318D1 (de)
DK (1) DK1515704T3 (de)
EA (1) EA007571B1 (de)
EC (1) ECSP055570A (de)
ES (1) ES2326218T3 (de)
FR (1) FR2841140B1 (de)
GE (1) GEP20074212B (de)
HR (1) HRP20050055B1 (de)
IL (1) IL165896A0 (de)
IS (1) IS2679B (de)
MA (1) MA27262A1 (de)
ME (1) ME00452B (de)
MX (1) MXPA05000086A (de)
NO (1) NO20050163L (de)
NZ (1) NZ537408A (de)
OA (1) OA12875A (de)
PL (1) PL374377A1 (de)
PT (1) PT1515704E (de)
RS (1) RS50914B (de)
SI (1) SI1515704T1 (de)
TN (1) TNSN04259A1 (de)
UA (1) UA81121C2 (de)
WO (1) WO2004000286A1 (de)
ZA (1) ZA200410333B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8101209B2 (en) * 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
BRPI0615607A2 (pt) * 2005-08-30 2011-05-24 Lek Pharmaceuticals composição farmacêutica compreendendo perindopril ou seus sais
FR2891459B1 (fr) * 2005-09-30 2007-12-28 Flamel Technologies Sa Microparticules a liberation modifiee d'au moins un principe actif et forme galenique orale en comprenant
FR2897865B1 (fr) * 2006-02-28 2008-04-18 Servier Lab Forme cristalline beta du sel d'arginine du perindopril, son procede de preparation, et les compositions pharmaceutiques qui la contiennent
FI125776B2 (fi) 2008-06-27 2023-07-28 Metsaeliitto Osuuskunta Menetelmä puulevyn käsittelemiseksi
CN106983731A (zh) * 2017-04-20 2017-07-28 上药东英(江苏)药业有限公司 一种培哚普利控释片及其制备方法
DE102018123500A1 (de) 2018-09-25 2020-03-26 Man Energy Solutions Se Vorrichtung und Verfahren zur Einstellung der Länge einer Pleuelstange eines Zylinders einer Brennkraftmaschine

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2247186A1 (de) * 1972-09-26 1974-03-28 Bayer Ag Antimykotisches mittel
JPS55129219A (en) * 1979-03-29 1980-10-06 Asahi Chem Ind Co Ltd Slow-releasing preparation
HU218673B (hu) * 1993-10-07 2000-10-28 Euroceltique S.A. Opioid analgetikumot tartalmazó elnyújtott hatóanyag-felszabadítású orális gyógyszerkészítmény és eljárás előállítására
DE19724696A1 (de) * 1997-06-12 1998-12-24 Hexal Ag Pharmazeutische Zubereitung mit drei Pelletarten
FR2771010B1 (fr) * 1997-11-19 2003-08-15 Adir Utilisation d'une combinaison d'un inhibiteur de l'enzyme de conversion de l'angiotensine et d'un diuretique pour le traitement des desordres microcirculatoires
JPH11171769A (ja) * 1997-12-05 1999-06-29 Nichiko Pharmaceutical Co Ltd 3−イソブチリル−2−イソプロピルピラゾロ〔1,5−a〕ピリジンの徐放性製剤及びその製法
GB9910773D0 (en) * 1999-05-11 1999-07-07 West Pharm Serv Drug Res Ltd Novel single unit coated dosage forms that can be used to minimise the effect of food on the absorption of drugs from the gastrointestinal tract
CA2409437A1 (en) * 2000-05-11 2001-11-22 Pharmacia Corporation Aldosterone antagonist composition for release during aldosterone acrophase
PT1492511E (pt) * 2002-04-09 2009-04-09 Flamel Tech Sa Formulação farmacêutica oral na forma de suspensão aquosa de microcápsulas para libertação modificada de princípio(s) activo(s)
CN1189150C (zh) * 2002-11-07 2005-02-16 张凤英 祛斑美白面膜
CN100389300C (zh) * 2004-01-17 2008-05-21 湖北清江水布垭工程建设公司 大坝面板挠度或坝体内部变形监测方法及装置

Also Published As

Publication number Publication date
BR0312026A (pt) 2005-03-22
DK1515704T3 (da) 2009-07-20
SI1515704T1 (sl) 2009-08-31
ECSP055570A (es) 2006-04-19
AP2029A (en) 2009-08-24
CA2491172A1 (fr) 2003-12-31
MXPA05000086A (es) 2005-04-08
JP4723243B2 (ja) 2011-07-13
WO2004000286A1 (fr) 2003-12-31
ZA200410333B (en) 2006-07-26
EP1515704A1 (de) 2005-03-23
HRP20050055B1 (hr) 2013-11-08
KR100722082B1 (ko) 2007-05-25
PT1515704E (pt) 2009-05-20
IS7634A (is) 2005-01-07
JP2005533079A (ja) 2005-11-04
CN100345541C (zh) 2007-10-31
AU2003260620A1 (en) 2004-01-06
RS50914B (sr) 2010-08-31
ES2326218T3 (es) 2009-10-05
CN1665491A (zh) 2005-09-07
CR7648A (es) 2005-07-18
DE60327318D1 (de) 2009-06-04
HRP20050055A2 (en) 2005-02-28
FR2841140A1 (fr) 2003-12-26
NZ537408A (en) 2006-07-28
OA12875A (en) 2006-09-15
KR20050023337A (ko) 2005-03-09
AP2004003193A0 (en) 2004-12-31
EA200500030A1 (ru) 2005-06-30
FR2841140B1 (fr) 2004-10-01
IL165896A0 (en) 2006-01-15
TNSN04259A1 (fr) 2007-03-12
US20060165808A1 (en) 2006-07-27
PL374377A1 (en) 2005-10-17
MA27262A1 (fr) 2005-03-01
EA007571B1 (ru) 2006-12-29
AR040461A1 (es) 2005-04-06
EP1515704B1 (de) 2009-04-22
NO20050163L (no) 2005-01-12
ME00452B (me) 2011-10-10
GEP20074212B (en) 2007-10-10
IS2679B (is) 2010-09-15
AU2003260620B2 (en) 2008-07-31
RS112904A (en) 2007-02-05
UA81121C2 (en) 2007-12-10
CY1109154T1 (el) 2014-07-02
CA2491172C (fr) 2011-02-15

Similar Documents

Publication Publication Date Title
CY2015015I1 (el) Παραγωγη τιακουμυκινης
ATE333463T1 (de) Selektive dipeptidische inhibitoren von kallikrein
DE60325567D1 (de) Matrix für die modifizierte freigabe von aktiven substanzen
DE60321662D1 (de) Für die zementierung von bohrlöchern
DE50210154D1 (de) Mikrokapseln
NO20044432L (no) Nye forbindelser
NO20050118D0 (no) Substituerte fenylsulfonamidinhibitorer av beta-amyolid produksjon
DE60328138D1 (de) Zwischenprodukte für die Herstellung von Dioxan-2-alkylcarbamaten
ATA7262002A (de) Fertigungssystem
DE502004005362D1 (de) Auslegung von werkzeugen und prozessen für die umformtechnik
ATE370929T1 (de) Cyclohexyl-harnstoff-derivate
ATE429214T1 (de) Mikrokapseln für die verzögerte kontrollierte freisetzung von perindopril
DE60318401D1 (de) Hydrierung von terephthalsäurerestehaltigen polyesteroligomeren
DE60326247D1 (de) Cr-STAHL FüR DIE BAUANWENDUNG UND HERSTELLUNGSVERFAHREN DAFüR
FR2841883B1 (fr) Butoir pour quai
DE50302582D1 (de) Schnapp-Kugelzapfen
FR2837224B1 (fr) Bonde traitante
NO20044098L (no) Nye forbindelser
FR2843451B1 (fr) Fronde du type lance-pierres
DE50308413D1 (de) Kontaktierung von nanoröhren
DE60302922D1 (de) Hydrierung von prochiralen Ketonen
FI20021791A0 (fi) Valaisimien ryhmävalvonta
UA6909S (uk) Комплект емблем
ATE314368T1 (de) Hydrierung von prochiralen ketonen
UA7370S (uk) Комплект етикеток

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1515704

Country of ref document: EP