ATE427931T1 - Analgetische verbindungen, deren synthese und pharmazeutische zusammensetzungen, die diese enthalten - Google Patents

Analgetische verbindungen, deren synthese und pharmazeutische zusammensetzungen, die diese enthalten

Info

Publication number
ATE427931T1
ATE427931T1 AT04794857T AT04794857T ATE427931T1 AT E427931 T1 ATE427931 T1 AT E427931T1 AT 04794857 T AT04794857 T AT 04794857T AT 04794857 T AT04794857 T AT 04794857T AT E427931 T1 ATE427931 T1 AT E427931T1
Authority
AT
Austria
Prior art keywords
synthesis
pharmaceutical compositions
compositions containing
containing same
analgesic compounds
Prior art date
Application number
AT04794857T
Other languages
German (de)
English (en)
Inventor
Nicolas Bazan
Anthony Vaccarino
Carlos Sunkel
Julio Builla
Original Assignee
Univ Louisiana State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Louisiana State filed Critical Univ Louisiana State
Application granted granted Critical
Publication of ATE427931T1 publication Critical patent/ATE427931T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/16Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
    • C07C311/19Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT04794857T 2003-10-09 2004-10-12 Analgetische verbindungen, deren synthese und pharmazeutische zusammensetzungen, die diese enthalten ATE427931T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/682,744 US6806291B1 (en) 2003-10-09 2003-10-09 Analgesic compounds, their synthesis and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
ATE427931T1 true ATE427931T1 (de) 2009-04-15

Family

ID=33132107

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04794857T ATE427931T1 (de) 2003-10-09 2004-10-12 Analgetische verbindungen, deren synthese und pharmazeutische zusammensetzungen, die diese enthalten

Country Status (9)

Country Link
US (1) US6806291B1 (enExample)
EP (1) EP1682496B1 (enExample)
JP (2) JP4568726B2 (enExample)
AT (1) ATE427931T1 (enExample)
AU (1) AU2004279880B2 (enExample)
CA (1) CA2544648C (enExample)
DE (1) DE602004020494D1 (enExample)
ES (1) ES2325163T3 (enExample)
WO (1) WO2005035485A2 (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2246058A1 (en) * 1997-09-04 2010-11-03 Novoneuron, Inc. Noribogaine in the treatment of pain and drug addiction
JP2009509659A (ja) * 2005-09-30 2009-03-12 Tti・エルビュー株式会社 生体界面への活性物質の送達のイオントフォレーシス装置及び方法
WO2008021896A2 (en) * 2006-08-08 2008-02-21 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Therapeutic methods for neuropathic pain
US8362007B1 (en) 2010-05-11 2013-01-29 Demerx, Inc. Substituted noribogaine
US9394294B2 (en) 2010-05-11 2016-07-19 Demerx, Inc. Methods and compositions for preparing and purifying noribogaine
US8765737B1 (en) 2010-05-11 2014-07-01 Demerx, Inc. Methods and compositions for preparing and purifying noribogaine
US8802832B2 (en) 2010-06-22 2014-08-12 Demerx, Inc. Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier
US9586954B2 (en) 2010-06-22 2017-03-07 Demerx, Inc. N-substituted noribogaine prodrugs
US8637648B1 (en) 2010-06-22 2014-01-28 Demerx, Inc. Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier
US8741891B1 (en) 2010-06-22 2014-06-03 Demerx, Inc. N-substituted noribogaine prodrugs
UA111065C2 (uk) 2010-07-23 2016-03-25 Демеркс, Інк. Композиції норибогаїну
EP2481740B1 (en) 2011-01-26 2015-11-04 DemeRx, Inc. Methods and compositions for preparing noribogaine from voacangine
US9617274B1 (en) 2011-08-26 2017-04-11 Demerx, Inc. Synthetic noribogaine
US20130096170A1 (en) 2011-10-14 2013-04-18 Hospira, Inc. Methods of treating pediatric patients using dexmedetomidine
CA2855994A1 (en) 2011-12-09 2013-06-13 Demerx, Inc. Phosphate esters of noribogaine
US8242158B1 (en) 2012-01-04 2012-08-14 Hospira, Inc. Dexmedetomidine premix formulation
CA2858820C (en) 2012-01-25 2021-08-17 Demerx, Inc. Synthetic voacangine
US9150584B2 (en) 2012-01-25 2015-10-06 Demerx, Inc. Indole and benzofuran fused isoquinuclidene derivatives and processes for preparing them
US9045481B2 (en) 2012-12-20 2015-06-02 Demerx, Inc. Substituted noribogaine
US8940728B2 (en) 2012-12-20 2015-01-27 Demerx, Inc. Substituted noribogaine
WO2014098877A1 (en) 2012-12-20 2014-06-26 Demerx, Inc. Substituted noribogaine
US9550789B2 (en) 2014-06-18 2017-01-24 Demerx, Inc. Halogenated indole and benzofuran derivatives of isoquinuclidene and processes for preparing them
PL3672938T3 (pl) * 2017-08-25 2024-06-17 The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Związki łagodzące ból

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3700773A (en) * 1969-06-25 1972-10-24 Merck & Co Inc Substituted phenylsulfamyl salicyclic acids and derivatives thereof in the treatment of inflammation
DE4010536A1 (de) * 1990-04-02 1991-10-10 Boehringer Mannheim Gmbh Pharmazeutische waessrige loesung von 4-(2-(benzolsulfonylamino)-ethyl)-phenoxyessigsaeure
US5554636A (en) 1995-04-21 1996-09-10 Lsu Medical Center Foundation N-acylated 4-hydroxphenylamine derivatives with analgesic properties and pharmaceutical compositions containing them
JP2000103778A (ja) * 1997-05-15 2000-04-11 Ono Pharmaceut Co Ltd ベンゼンスルフォンアミド化合物、それらの製造方法およびそれらを有効成分として含有するプロスタグランジンe2受容体拮抗剤
IL138686A0 (en) * 1999-10-01 2001-10-31 Pfizer Prod Inc α- SULFONYLAMINO HYDROXAMIC ACID INHIBITORS OF MATRIX METALLOPROTEINASES FOR THE TREATMENT OF PERIPHERAL OR CENTRAL NERVOUS SYSTEM DISORDERS
TWI239942B (en) * 2001-06-11 2005-09-21 Dainippon Pharmaceutical Co N-arylphenylacetamide derivative and pharmaceutical composition containing the same

Also Published As

Publication number Publication date
DE602004020494D1 (de) 2009-05-20
JP2010195826A (ja) 2010-09-09
AU2004279880A1 (en) 2005-04-21
AU2004279880B2 (en) 2010-09-16
EP1682496B1 (en) 2009-04-08
WO2005035485A2 (en) 2005-04-21
JP4568726B2 (ja) 2010-10-27
US6806291B1 (en) 2004-10-19
WO2005035485A3 (en) 2005-06-09
ES2325163T3 (es) 2009-08-27
EP1682496A2 (en) 2006-07-26
CA2544648A1 (en) 2005-04-21
CA2544648C (en) 2011-05-24
JP2007508325A (ja) 2007-04-05

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