ATE427737T1 - Mikroemulsionen von retinoiden und diese enthaltende pharmazeutische zusammensetzungen - Google Patents

Mikroemulsionen von retinoiden und diese enthaltende pharmazeutische zusammensetzungen

Info

Publication number
ATE427737T1
ATE427737T1 AT04790188T AT04790188T ATE427737T1 AT E427737 T1 ATE427737 T1 AT E427737T1 AT 04790188 T AT04790188 T AT 04790188T AT 04790188 T AT04790188 T AT 04790188T AT E427737 T1 ATE427737 T1 AT E427737T1
Authority
AT
Austria
Prior art keywords
microemulsions
retinoids
pharmaceutical compositions
compositions containing
containing same
Prior art date
Application number
AT04790188T
Other languages
English (en)
Inventor
Enea Menegatti
Rita Cortesi
Elisabetta Esposito
Pierangelo Bellato
Giovanni Gennari
Original Assignee
Fidia Farmaceutici
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia Farmaceutici filed Critical Fidia Farmaceutici
Application granted granted Critical
Publication of ATE427737T1 publication Critical patent/ATE427737T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
AT04790188T 2003-10-17 2004-10-08 Mikroemulsionen von retinoiden und diese enthaltende pharmazeutische zusammensetzungen ATE427737T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT002019A ITMI20032019A1 (it) 2003-10-17 2003-10-17 Microemulsioni di retinoidi e composizioni farmaceutiche che le contengono

Publications (1)

Publication Number Publication Date
ATE427737T1 true ATE427737T1 (de) 2009-04-15

Family

ID=34509450

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04790188T ATE427737T1 (de) 2003-10-17 2004-10-08 Mikroemulsionen von retinoiden und diese enthaltende pharmazeutische zusammensetzungen

Country Status (12)

Country Link
US (1) US7781489B2 (de)
EP (1) EP1673065B1 (de)
JP (1) JP2007508339A (de)
AT (1) ATE427737T1 (de)
AU (1) AU2004283432B2 (de)
CA (1) CA2542663C (de)
DE (1) DE602004020488D1 (de)
ES (1) ES2322472T3 (de)
IT (1) ITMI20032019A1 (de)
PL (1) PL1673065T3 (de)
SI (1) SI1673065T1 (de)
WO (1) WO2005039532A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ541526A (en) * 2003-01-24 2008-03-28 Stiefel Res Australia Pty Ltd Clindamycin phosphate foam
FR2865651B1 (fr) * 2004-01-29 2007-09-28 Fabre Pierre Dermo Cosmetique Compositions topiques associant des fragments de hyaluronate de sodium et un retinoide utiles en dermatologie cosmetique et medicale
FR2894827B1 (fr) * 2005-12-21 2010-10-29 Galderma Res & Dev Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation,et leurs utilisations
EP2013016B8 (de) * 2006-03-29 2014-10-08 Wayne State University Liposomale nanopartikel und andere fenretinid-formulierungen für die therapie und wirkstofffreisetzung
EP1967180A1 (de) * 2007-03-06 2008-09-10 Almirall Hermal GmbH Topische Zusammensetzung enthaltend einen Retinoid-Rezeptor-Agonist
EP2155149A2 (de) * 2007-05-11 2010-02-24 Galderma Research & Development Pharmazeutische oder kosmetische präparate zur topischen und/oder parenteralen anwendung, verfahren zu ihrer herstellung und ihre anwendung
DE102008034944B4 (de) * 2008-07-26 2017-03-16 Arivine Pharma Ag Mikroemulsion
US9750812B2 (en) * 2008-09-27 2017-09-05 Jina Pharmaceuticals, Inc. Lipid based pharmaceutical preparations for oral and topical application; their compositions, methods, and uses thereof
PT2400951T (pt) 2009-02-25 2018-11-26 Mayne Pharma Llc Composições de espuma tópica
US9018236B2 (en) * 2012-03-22 2015-04-28 Precision Dermatology, Inc. Cyclodextrin-based microemulsions, and dermatological uses thereof
WO2013178749A1 (fr) 2012-06-01 2013-12-05 Galderma Research & Development Nanocapsules lipidiques comprenant un rétinoide, nanodispersion et composition les contenant, leur procédé de préparation et leur utilisation en dermatologie
US10125400B2 (en) 2012-08-10 2018-11-13 Galmerma Research & Development Method for the diagnosis of rosacea
CN105934239A (zh) 2013-12-04 2016-09-07 盖尔德马研究及发展公司 优选包含亲脂性活性剂的脂质微胶囊和包含它的组合物，它们的制备方法和它们在皮肤病学和化妆品中的用途
WO2016193588A1 (fr) 2015-05-29 2016-12-08 Galderma Research & Development Compositions comprenant au moins un principe actif disperse et des microcapsules lipidiques
ES2785322T3 (es) 2016-10-11 2020-10-06 Ionia Azure Ag Microemulsión de agua en aceite cosmética
WO2022091140A1 (en) * 2020-11-01 2022-05-05 Idrs Labs Pvt Ltd Oral liquid pharmaceutical compositions of isotretinoin

Family Cites Families (20)

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Publication number Priority date Publication date Assignee Title
IT1212892B (it) * 1983-10-11 1989-11-30 Della Valle Francesco Acido ialuronico ottenuto per mezzodi filtrazione molecolare sprovvisto di attivita' infiammatoria e sua utilizzazione terapeutica
US5023271A (en) * 1985-08-13 1991-06-11 California Biotechnology Inc. Pharmaceutical microemulsions
JPS63500456A (ja) * 1985-08-13 1988-02-18 カリフオルニア　バイオテクノロジ−　インコ−ポレイテツド 薬剤に用いるミクロエマルジョン
JPS6245336A (ja) 1985-08-21 1987-02-27 Toyo Biyuut Kk 乳化組成物
JPS6295132A (ja) * 1985-10-21 1987-05-01 Nippon Saafuakutanto Kogyo Kk 多価アルコ−ル中油型乳化組成物
US5055303A (en) * 1989-01-31 1991-10-08 Kv Pharmaceutical Company Solid controlled release bioadherent emulsions
JPH03293024A (ja) * 1990-04-11 1991-12-24 Nikko Kemikaruzu Kk レシチンが水相に分散して成る油中水型エマルション
US5110606A (en) * 1990-11-13 1992-05-05 Affinity Biotech, Inc. Non-aqueous microemulsions for drug delivery
GB9214634D0 (en) * 1992-07-09 1992-08-19 Lalvani Kartar S A cosmetic or pharmaceutical preparation
US5744155A (en) * 1993-08-13 1998-04-28 Friedman; Doron Bioadhesive emulsion preparations for enhanced drug delivery
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TWI241915B (en) * 1998-05-11 2005-10-21 Ciba Sc Holding Ag A method of preparing a pharmaceutical end formulation using a nanodispersion
DE19826503A1 (de) * 1998-06-13 1999-12-16 Beiersdorf Ag Kosmetische und dermatologische Zubereitungen mit einem Gehalt an Chitosan und Phospholipiden
JP2000204011A (ja) 1999-01-13 2000-07-25 Human Limited:Kk 殺菌・制菌・消臭・皮膚保水性向上液の製法
JP2001181180A (ja) * 1999-12-24 2001-07-03 Lion Corp 油中水型乳化組成物
JP4430770B2 (ja) * 2000-01-07 2010-03-10 花王株式会社 皮膚弾力性改善剤
EP1345589B1 (de) * 2000-11-29 2007-06-27 Lyotropic Therapeutics, Inc. Lösungsmittelsysteme für pharmazeutische mittel
DE60136648D1 (de) * 2000-12-05 2009-01-02 Los Angeles Childrens Hospital Pharmazeutische zusammensetzungen von fenretinid mit erhöhter bioverfügbarkeit und verfahren zu deren verwendung
US6551605B2 (en) * 2001-04-06 2003-04-22 Haarmann & Reimer Diesters or polyesters of naphthalene dicarboxylic acid as solubilizer/stabilizer for retinoids
US7820145B2 (en) * 2003-08-04 2010-10-26 Foamix Ltd. Oleaginous pharmaceutical and cosmetic foam

Also Published As

Publication number Publication date
ITMI20032019A1 (it) 2005-04-18
JP2007508339A (ja) 2007-04-05
WO2005039532A1 (en) 2005-05-06
US7781489B2 (en) 2010-08-24
DE602004020488D1 (de) 2009-05-20
SI1673065T1 (sl) 2009-08-31
CA2542663C (en) 2012-11-27
EP1673065B1 (de) 2009-04-08
US20070134276A1 (en) 2007-06-14
CA2542663A1 (en) 2005-05-06
PL1673065T3 (pl) 2009-09-30
AU2004283432A1 (en) 2005-05-06
EP1673065A1 (de) 2006-06-28
ES2322472T3 (es) 2009-06-22
AU2004283432B2 (en) 2010-02-11

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