ATE427737T1 - Mikroemulsionen von retinoiden und diese enthaltende pharmazeutische zusammensetzungen - Google Patents

Mikroemulsionen von retinoiden und diese enthaltende pharmazeutische zusammensetzungen

Info

Publication number
ATE427737T1
ATE427737T1 AT04790188T AT04790188T ATE427737T1 AT E427737 T1 ATE427737 T1 AT E427737T1 AT 04790188 T AT04790188 T AT 04790188T AT 04790188 T AT04790188 T AT 04790188T AT E427737 T1 ATE427737 T1 AT E427737T1
Authority
AT
Austria
Prior art keywords
microemulsions
retinoids
pharmaceutical compositions
compositions containing
containing same
Prior art date
Application number
AT04790188T
Other languages
English (en)
Inventor
Enea Menegatti
Rita Cortesi
Elisabetta Esposito
Pierangelo Bellato
Giovanni Gennari
Original Assignee
Fidia Farmaceutici
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia Farmaceutici filed Critical Fidia Farmaceutici
Application granted granted Critical
Publication of ATE427737T1 publication Critical patent/ATE427737T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
AT04790188T 2003-10-17 2004-10-08 Mikroemulsionen von retinoiden und diese enthaltende pharmazeutische zusammensetzungen ATE427737T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT002019A ITMI20032019A1 (it) 2003-10-17 2003-10-17 Microemulsioni di retinoidi e composizioni farmaceutiche che le contengono

Publications (1)

Publication Number Publication Date
ATE427737T1 true ATE427737T1 (de) 2009-04-15

Family

ID=34509450

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04790188T ATE427737T1 (de) 2003-10-17 2004-10-08 Mikroemulsionen von retinoiden und diese enthaltende pharmazeutische zusammensetzungen

Country Status (12)

Country Link
US (1) US7781489B2 (de)
EP (1) EP1673065B1 (de)
JP (1) JP2007508339A (de)
AT (1) ATE427737T1 (de)
AU (1) AU2004283432B2 (de)
CA (1) CA2542663C (de)
DE (1) DE602004020488D1 (de)
ES (1) ES2322472T3 (de)
IT (1) ITMI20032019A1 (de)
PL (1) PL1673065T3 (de)
SI (1) SI1673065T1 (de)
WO (1) WO2005039532A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR042906A1 (es) * 2003-01-24 2005-07-06 Connetics Australia Pty Ltd Espuma de fosfato de clindamicina sensible a la temperatura y metodo de tratamiento de acne que la utiliza
FR2865651B1 (fr) * 2004-01-29 2007-09-28 Fabre Pierre Dermo Cosmetique Compositions topiques associant des fragments de hyaluronate de sodium et un retinoide utiles en dermatologie cosmetique et medicale
FR2894827B1 (fr) * 2005-12-21 2010-10-29 Galderma Res & Dev Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation,et leurs utilisations
WO2007115134A2 (en) 2006-03-29 2007-10-11 Wayne State University Liposomal nanoparticles and other formulations of fenretinide for use in therapy and drug delivery
EP1967180A1 (de) * 2007-03-06 2008-09-10 Almirall Hermal GmbH Topische Zusammensetzung enthaltend einen Retinoid-Rezeptor-Agonist
CA2686558A1 (fr) * 2007-05-11 2008-12-11 Galderma Research & Development Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation, et leurs utilisations
DE102008034944B4 (de) * 2008-07-26 2017-03-16 Arivine Pharma Ag Mikroemulsion
JP2012504135A (ja) * 2008-09-27 2012-02-16 ジャイナ ファーマシューティカルズ，インコーポレーテッド 経口適用および局所適用のための脂質系薬学的調製物、ならびにそれらの組成物、方法、および使用
WO2010096868A1 (en) 2009-02-25 2010-09-02 Stiefel Research Australia Pty Ltd Topical foam composition
WO2013142247A1 (en) * 2012-03-22 2013-09-26 Precision Dermatology, Inc. Cyclodextrin-based microemulsions, and dermatological uses thereof
US10702604B2 (en) 2012-06-01 2020-07-07 Galderma Research & Development Lipid nanocapsules comprising a retinoid, nanodispersion and composition containing the same, process for preparing the same and use thereof in dermatology
EP2882865B1 (de) 2012-08-10 2017-09-27 Galderma Research & Development Verfahren zur diagnose von rosacea
AU2014359195B2 (en) 2013-12-04 2020-02-27 Galderma Research & Development Lipid microcapsules preferably comprising a lipophilic active substance and composition containing same, method for the production thereof, and use of same in dermatology and in cosmetics
EP3302421B1 (de) 2015-05-29 2021-07-07 Galderma Research & Development Zusammensetzungen mit mindestens einem dispergierten wirkstoff und lipid-mikrokapseln
EP3308766B1 (de) 2016-10-11 2019-12-25 Ionia Azure AG Kosmetische wasser-in-öl-mikroemulsion
WO2022091140A1 (en) * 2020-11-01 2022-05-05 Idrs Labs Pvt Ltd Oral liquid pharmaceutical compositions of isotretinoin

Family Cites Families (20)

* Cited by examiner, † Cited by third party
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IT1212892B (it) * 1983-10-11 1989-11-30 Della Valle Francesco Acido ialuronico ottenuto per mezzodi filtrazione molecolare sprovvisto di attivita' infiammatoria e sua utilizzazione terapeutica
JPS63500456A (ja) * 1985-08-13 1988-02-18 カリフオルニア　バイオテクノロジ−　インコ−ポレイテツド 薬剤に用いるミクロエマルジョン
US5023271A (en) * 1985-08-13 1991-06-11 California Biotechnology Inc. Pharmaceutical microemulsions
JPS6245336A (ja) * 1985-08-21 1987-02-27 Toyo Biyuut Kk 乳化組成物
JPS6295132A (ja) * 1985-10-21 1987-05-01 Nippon Saafuakutanto Kogyo Kk 多価アルコ−ル中油型乳化組成物
US5055303A (en) * 1989-01-31 1991-10-08 Kv Pharmaceutical Company Solid controlled release bioadherent emulsions
JPH03293024A (ja) * 1990-04-11 1991-12-24 Nikko Kemikaruzu Kk レシチンが水相に分散して成る油中水型エマルション
US5110606A (en) * 1990-11-13 1992-05-05 Affinity Biotech, Inc. Non-aqueous microemulsions for drug delivery
GB9214634D0 (en) * 1992-07-09 1992-08-19 Lalvani Kartar S A cosmetic or pharmaceutical preparation
US5744155A (en) * 1993-08-13 1998-04-28 Friedman; Doron Bioadhesive emulsion preparations for enhanced drug delivery
JPH1118697A (ja) * 1997-07-09 1999-01-26 Toyo Beauty Kk 含油ゲル状組成物及び水中油型乳化組成物
TWI241915B (en) * 1998-05-11 2005-10-21 Ciba Sc Holding Ag A method of preparing a pharmaceutical end formulation using a nanodispersion
DE19826503A1 (de) * 1998-06-13 1999-12-16 Beiersdorf Ag Kosmetische und dermatologische Zubereitungen mit einem Gehalt an Chitosan und Phospholipiden
JP2000204011A (ja) 1999-01-13 2000-07-25 Human Limited:Kk 殺菌・制菌・消臭・皮膚保水性向上液の製法
JP2001181180A (ja) * 1999-12-24 2001-07-03 Lion Corp 油中水型乳化組成物
JP4430770B2 (ja) * 2000-01-07 2010-03-10 花王株式会社 皮膚弾力性改善剤
ATE365536T1 (de) * 2000-11-29 2007-07-15 Lyotropic Therapeutics Inc Lösungsmittelsysteme für pharmazeutische mittel
ES2316489T3 (es) * 2000-12-05 2009-04-16 Childrens Hospital Los Angeles Composiciones farmaceuticas de fenretinida que tienen biodisponibilidad aumentada y metodos de uso de las mismas.
US6551605B2 (en) * 2001-04-06 2003-04-22 Haarmann & Reimer Diesters or polyesters of naphthalene dicarboxylic acid as solubilizer/stabilizer for retinoids
US7820145B2 (en) * 2003-08-04 2010-10-26 Foamix Ltd. Oleaginous pharmaceutical and cosmetic foam

Also Published As

Publication number Publication date
PL1673065T3 (pl) 2009-09-30
EP1673065A1 (de) 2006-06-28
AU2004283432B2 (en) 2010-02-11
CA2542663C (en) 2012-11-27
WO2005039532A1 (en) 2005-05-06
AU2004283432A1 (en) 2005-05-06
JP2007508339A (ja) 2007-04-05
CA2542663A1 (en) 2005-05-06
EP1673065B1 (de) 2009-04-08
US20070134276A1 (en) 2007-06-14
DE602004020488D1 (de) 2009-05-20
ES2322472T3 (es) 2009-06-22
ITMI20032019A1 (it) 2005-04-18
SI1673065T1 (sl) 2009-08-31
US7781489B2 (en) 2010-08-24

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