ATE425170T1 - Kristallformen der zoledronsäure und deren natrioumsalze, amorphes natriumzoledronat und verfahren zu deren herstellung - Google Patents

Kristallformen der zoledronsäure und deren natrioumsalze, amorphes natriumzoledronat und verfahren zu deren herstellung

Info

Publication number
ATE425170T1
ATE425170T1 AT04756693T AT04756693T ATE425170T1 AT E425170 T1 ATE425170 T1 AT E425170T1 AT 04756693 T AT04756693 T AT 04756693T AT 04756693 T AT04756693 T AT 04756693T AT E425170 T1 ATE425170 T1 AT E425170T1
Authority
AT
Austria
Prior art keywords
sodium
zoledronic acid
amorphic
production
zoledronate
Prior art date
Application number
AT04756693T
Other languages
English (en)
Inventor
Judith Aronhime
Revital Lifshitz-Liron
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharma filed Critical Teva Pharma
Application granted granted Critical
Publication of ATE425170T1 publication Critical patent/ATE425170T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6503—Five-membered rings
    • C07F9/6506—Five-membered rings having the nitrogen atoms in positions 1 and 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT04756693T 2003-07-03 2004-07-06 Kristallformen der zoledronsäure und deren natrioumsalze, amorphes natriumzoledronat und verfahren zu deren herstellung ATE425170T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US48487603P 2003-07-03 2003-07-03

Publications (1)

Publication Number Publication Date
ATE425170T1 true ATE425170T1 (de) 2009-03-15

Family

ID=34062065

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04756693T ATE425170T1 (de) 2003-07-03 2004-07-06 Kristallformen der zoledronsäure und deren natrioumsalze, amorphes natriumzoledronat und verfahren zu deren herstellung

Country Status (8)

Country Link
US (7) US20050054616A1 (de)
EP (2) EP1612212A1 (de)
AT (1) ATE425170T1 (de)
CA (1) CA2530193A1 (de)
DE (1) DE602004019881D1 (de)
ES (1) ES2322592T3 (de)
IL (1) IL172513A0 (de)
WO (1) WO2005005447A2 (de)

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US10173986B2 (en) * 2012-05-14 2019-01-08 Antecip Bioventures Ii Llc Methods for the safe administration of imidazole or imidazolium compounds
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US9844559B2 (en) 2012-05-14 2017-12-19 Antecip Bioventures Ii Llc Neridronic acid for treating bone marrow lesions
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US9925203B2 (en) 2012-05-14 2018-03-27 Antecip Bioventures Ii Llc Compositions for administration of zoledronic acid or related compounds for treating low back pain
US10092581B2 (en) 2014-05-15 2018-10-09 Antecip Bioventures Ii Llc Osteoclast inhibitors such as zoledronic acid for low back pain treatment
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US10463682B2 (en) 2012-05-14 2019-11-05 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating low back pain
US9827192B2 (en) 2012-05-14 2017-11-28 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome
US9717747B2 (en) 2012-05-14 2017-08-01 Antecip Bioventures Ii Llc Osteoclast inhibitors for knee conditions
US9662343B2 (en) 2012-05-14 2017-05-30 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome
NZ702414A (en) * 2012-05-14 2016-10-28 Antecip Bioventures Ii Llc Compositions comprising zoledronic acid or related compounds for relieving inflammatory pain and related conditions
US10493085B2 (en) 2012-05-14 2019-12-03 Antecip Bioventures Ii Llc Neridronic acid and other bisphosphonates for treating complex regional pain syndrome and other diseases
US10413561B2 (en) 2012-05-14 2019-09-17 Antecip Bioventures Ii Llc Neridronic acid and other bisphosphonates for treating complex regional pain syndrome and other diseases
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US9427403B2 (en) 2012-05-14 2016-08-30 Antecip Bioventures Ii Llc Methods for the safe administration of imidazole or imidazolium compounds
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US9616078B2 (en) 2012-05-14 2017-04-11 Antecip Bioventures Ii Llc Dosage forms for oral administration of zoledronic acid or related compounds for treating disease
US9655908B2 (en) 2012-05-14 2017-05-23 Antecip Bioventures Ii Llc Neridronic acid molecular complex for treating complex regional pain syndrome
US8865757B1 (en) 2014-05-28 2014-10-21 Antecip Bioventures Ii Llp Therapeutic compositions comprising imidazole and imidazolium compounds
US9789128B2 (en) 2012-05-14 2017-10-17 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome
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US9669040B2 (en) 2012-05-14 2017-06-06 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome
US9770457B2 (en) 2012-05-14 2017-09-26 Antecip Bioventures Ii Llc Neridronic acid for treating bone marrow lesion
US10034890B2 (en) 2012-05-14 2018-07-31 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome
US10016445B2 (en) 2012-05-14 2018-07-10 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome
US11654152B2 (en) 2012-05-14 2023-05-23 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating disease
US10413560B2 (en) 2012-05-14 2019-09-17 Antecip Bioventures Ii Llc Dosage forms for oral administration of zoledronic acid or related compounds for treating disease
CA2928350C (en) * 2013-10-25 2018-01-09 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating disease
KR102495018B1 (ko) 2013-11-15 2023-02-06 아케비아 테라퓨틱스 인코포레이티드 ｛[5-(3-클로로페닐)-3-하이드록시피리딘-2-카보닐]아미노｝아세트산의 고체형, 이의 조성물 및 용도
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Also Published As

Publication number Publication date
US20070027323A1 (en) 2007-02-01
US20070021389A1 (en) 2007-01-25
ES2322592T3 (es) 2009-06-23
WO2005005447A3 (en) 2005-07-07
IL172513A0 (en) 2006-04-10
US20050054616A1 (en) 2005-03-10
DE602004019881D1 (de) 2009-04-23
CA2530193A1 (en) 2005-01-20
US7582768B2 (en) 2009-09-01
US20070021617A1 (en) 2007-01-25
WO2005005447A2 (en) 2005-01-20
EP1567533B1 (de) 2009-03-11
EP1567533A2 (de) 2005-08-31
EP1612212A1 (de) 2006-01-04
US7687636B2 (en) 2010-03-30
US20070021618A1 (en) 2007-01-25
US20070021619A1 (en) 2007-01-25
US7589211B2 (en) 2009-09-15
US20070021616A1 (en) 2007-01-25
US7435827B2 (en) 2008-10-14

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