ATE424458T1 - Eg-vegf nukleinsäuren und polypeptide und verfahren zur deren verwendung - Google Patents

Eg-vegf nukleinsäuren und polypeptide und verfahren zur deren verwendung

Info

Publication number
ATE424458T1
ATE424458T1 AT01946701T AT01946701T ATE424458T1 AT E424458 T1 ATE424458 T1 AT E424458T1 AT 01946701 T AT01946701 T AT 01946701T AT 01946701 T AT01946701 T AT 01946701T AT E424458 T1 ATE424458 T1 AT E424458T1
Authority
AT
Austria
Prior art keywords
polypeptides
present
methods
vegf
nucleic acids
Prior art date
Application number
AT01946701T
Other languages
English (en)
Inventor
Napoleone Ferrara
Colin Watanabe
William Wood
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2000/032678 external-priority patent/WO2001040466A2/en
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ATE424458T1 publication Critical patent/ATE424458T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1858Platelet-derived growth factor [PDGF]
    • A61K38/1866Vascular endothelial growth factor [VEGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475Assays involving growth factors
    • G01N2333/515Angiogenesic factors; Angiogenin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/04Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Vascular Medicine (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
AT01946701T 2000-06-23 2001-06-22 Eg-vegf nukleinsäuren und polypeptide und verfahren zur deren verwendung ATE424458T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21363700P 2000-06-23 2000-06-23
US23097800P 2000-09-07 2000-09-07
PCT/US2000/032678 WO2001040466A2 (en) 1999-12-01 2000-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same

Publications (1)

Publication Number Publication Date
ATE424458T1 true ATE424458T1 (de) 2009-03-15

Family

ID=26908256

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01946701T ATE424458T1 (de) 2000-06-23 2001-06-22 Eg-vegf nukleinsäuren und polypeptide und verfahren zur deren verwendung

Country Status (13)

Country Link
US (4) US20020172678A1 (de)
EP (2) EP2075334B1 (de)
JP (1) JP5081361B2 (de)
KR (1) KR100871735B1 (de)
CN (2) CN1449445B (de)
AT (1) ATE424458T1 (de)
AU (3) AU6871401A (de)
CA (1) CA2412612C (de)
DE (1) DE60137847D1 (de)
DK (1) DK1294876T3 (de)
ES (1) ES2323569T3 (de)
MX (1) MXPA03000150A (de)
WO (1) WO2002000711A2 (de)

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WO2002036625A2 (en) 2000-11-03 2002-05-10 The Regents Of The University Of California Prokineticin polypeptides, related compositions and methods
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DK1399484T3 (da) * 2001-06-28 2010-11-08 Domantis Ltd Dobbelt-specifik ligand og anvendelse af denne
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JP2005538695A (ja) * 2002-04-15 2005-12-22 ザ リージェント オブ ザ ユニバーシティ オブ カリフォルニア 概日リズム障害を治療するためのスクリーニング法および治療法
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JP6320040B2 (ja) * 2013-12-27 2018-05-09 国立大学法人福井大学 抗prok1抗体及び抗vegf抗体併用による大腸癌の治療
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RU2662944C1 (ru) * 2017-02-17 2018-07-31 Общество с ограниченной ответственностью "Группа развития "АПЕКС" Средство для лечения состояний человеческого организма, связанных с уменьшением уровня экспрессии гена prok 1 и/или уменьшением количества белка прокинетицина 1 на основе генно-терапевтических субстанций с геном prok 1, способ получения и использования
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CN1449445A (zh) 2003-10-15
MXPA03000150A (es) 2003-09-22
US7727536B2 (en) 2010-06-01
US20020172678A1 (en) 2002-11-21
JP2004511432A (ja) 2004-04-15
US20070122412A1 (en) 2007-05-31
KR100871735B1 (ko) 2008-12-03
US20100254999A1 (en) 2010-10-07
WO2002000711A2 (en) 2002-01-03
US7446168B2 (en) 2008-11-04
CN101269214B (zh) 2013-09-04
KR20030011104A (ko) 2003-02-06
AU6871401A (en) 2002-01-08
EP1294876B1 (de) 2009-03-04
CA2412612C (en) 2013-04-30
ES2323569T3 (es) 2009-07-21
HK1059452A1 (en) 2004-07-02
EP2075334B1 (de) 2013-11-20
AU2001268714B2 (en) 2006-09-21
AU2006252241A1 (en) 2007-01-25
CN1449445B (zh) 2012-07-18
US20050064522A1 (en) 2005-03-24
AU2006252241B2 (en) 2010-03-04
WO2002000711A3 (en) 2002-06-20
HK1132298A1 (en) 2010-02-19
EP1294876A2 (de) 2003-03-26
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CA2412612A1 (en) 2002-01-03
DK1294876T3 (da) 2009-06-02

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