ATE417041T1 - Neue farnesylproteintransferaseinhibitoren als antitumormittel - Google Patents
Neue farnesylproteintransferaseinhibitoren als antitumormittelInfo
- Publication number
- ATE417041T1 ATE417041T1 AT04779960T AT04779960T ATE417041T1 AT E417041 T1 ATE417041 T1 AT E417041T1 AT 04779960 T AT04779960 T AT 04779960T AT 04779960 T AT04779960 T AT 04779960T AT E417041 T1 ATE417041 T1 AT E417041T1
- Authority
- AT
- Austria
- Prior art keywords
- transferas
- inhibitors
- tumor agents
- farnesyl protein
- new
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49326903P | 2003-08-07 | 2003-08-07 | |
US49850903P | 2003-08-28 | 2003-08-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE417041T1 true ATE417041T1 (de) | 2008-12-15 |
Family
ID=34138747
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT04779960T ATE417041T1 (de) | 2003-08-07 | 2004-08-04 | Neue farnesylproteintransferaseinhibitoren als antitumormittel |
Country Status (19)
Country | Link |
---|---|
US (1) | US7557107B2 (de) |
EP (1) | EP1660477B1 (de) |
JP (1) | JP2007501791A (de) |
KR (1) | KR20060057599A (de) |
AR (1) | AR045447A1 (de) |
AT (1) | ATE417041T1 (de) |
AU (1) | AU2004263493A1 (de) |
BR (1) | BRPI0413384A (de) |
CA (1) | CA2535210A1 (de) |
DE (1) | DE602004018332D1 (de) |
EC (1) | ECSP066349A (de) |
ES (1) | ES2317047T3 (de) |
HK (1) | HK1087122A1 (de) |
IL (1) | IL173514A0 (de) |
MX (1) | MXPA06001483A (de) |
PE (1) | PE20050336A1 (de) |
RU (1) | RU2006106768A (de) |
TW (1) | TW200510384A (de) |
WO (1) | WO2005014577A1 (de) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7342016B2 (en) * | 2000-08-30 | 2008-03-11 | Schering Corporation | Farnesyl protein transferase inhibitors as antitumor agents |
EP1506286B1 (de) * | 2002-05-24 | 2014-03-19 | Merck Sharp & Dohme Corp. | Neutralisierung eines menschlichen anti-igfr-antikörpers |
TW200412956A (en) * | 2002-09-30 | 2004-08-01 | Schering Corp | Methods for treating disorders of calcium homeostasis |
PE20050928A1 (es) * | 2003-11-21 | 2005-11-08 | Schering Corp | Combinaciones terapeuticas de anticuerpo anti-igfr1 |
US20060205810A1 (en) * | 2004-11-24 | 2006-09-14 | Schering Corporation | Platinum therapeutic combinations |
US20060205755A1 (en) * | 2004-12-21 | 2006-09-14 | Schering Corporation | Novel farnesyl protein transferase inhibitors as antitumor agents |
BRPI0607537A2 (pt) * | 2005-04-12 | 2009-09-15 | Elan Pharma Int Ltd | formulações de derivado de quinazolina nanoparticulado |
CN101222926B (zh) * | 2005-04-15 | 2013-07-17 | 默沙东公司 | 用于治疗或预防癌症的方法和组合物 |
CA2637572A1 (en) * | 2006-01-19 | 2007-07-26 | Schering Corporation | Piperazine derivatives as farnesyl protein transferase inhibitors |
EP1854465A1 (de) * | 2006-05-12 | 2007-11-14 | Alexander Tobias Teichmann | Verwendung von 4,17 beta-dihydroxyandrost-4-ene-3-one zur Behandlung von Krebs |
US20100111965A1 (en) * | 2006-10-11 | 2010-05-06 | Fusion Antibodies Limited | Combination therapy |
US8907095B2 (en) | 2007-10-22 | 2014-12-09 | Merck Sharp & Dohme Corp. | Bicyclic heterocycle derivatives and their use as modulators of the activity of GPR119 |
GB0807018D0 (en) | 2008-04-17 | 2008-05-21 | Fusion Antibodies Ltd | Antibodies and treatment |
EP2872161B1 (de) | 2012-06-26 | 2020-12-16 | Del Mar Pharmaceuticals | Dianhydrogalactitol zur verwendung bei der behandlung von tyrosinkinaseinhibitor-resistenten malignomen bei patienten mit genetischen polymorphismen oder ahi1-dysregulierungen oder mutationen |
EP2983674A4 (de) | 2013-04-08 | 2017-05-10 | Dennis M. Brown | Therapeutischer nutzen suboptimal verabreichter chemischer verbindungen |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL111235A (en) | 1993-10-15 | 2001-03-19 | Schering Plough Corp | Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them |
US5874442A (en) * | 1995-12-22 | 1999-02-23 | Schering-Plough Corporation | Tricyclic amides useful for inhibition of G-protein function and for treatment of proliferative disease |
NZ326035A (en) | 1995-12-22 | 2000-01-28 | Schering Corp | Tricyclic amides useful for inhibition of g-protein function and for treatment of proliferative diseases |
WO2001064199A2 (en) | 2000-02-29 | 2001-09-07 | Janssen Pharmaceutica N.V. | Farnesyl protein transferase inhibitor combinations with taxane compounds |
US7342016B2 (en) * | 2000-08-30 | 2008-03-11 | Schering Corporation | Farnesyl protein transferase inhibitors as antitumor agents |
US20030229099A1 (en) | 2000-08-30 | 2003-12-11 | Zhu Hugh Y. | Novel farnesyl protein transferase inhibitors as antitumor agents |
AR033680A1 (es) * | 2000-08-30 | 2004-01-07 | Schering Corp | Compuestos triciclicos utiles como inhibidores de la farnesil proteino transferasa y su uso para la manufactura de medicamentos como agentes antitumorales |
AU2002346644A1 (en) * | 2001-12-03 | 2003-06-17 | Schering Corporation | Use of fpt inhibitors and at least two antineoplastic agents in the treatment of cancer |
TW200412956A (en) * | 2002-09-30 | 2004-08-01 | Schering Corp | Methods for treating disorders of calcium homeostasis |
US20060205755A1 (en) * | 2004-12-21 | 2006-09-14 | Schering Corporation | Novel farnesyl protein transferase inhibitors as antitumor agents |
-
2004
- 2004-08-04 RU RU2006106768/04A patent/RU2006106768A/ru not_active Application Discontinuation
- 2004-08-04 CA CA002535210A patent/CA2535210A1/en not_active Abandoned
- 2004-08-04 MX MXPA06001483A patent/MXPA06001483A/es active IP Right Grant
- 2004-08-04 JP JP2006522672A patent/JP2007501791A/ja active Pending
- 2004-08-04 WO PCT/US2004/025042 patent/WO2005014577A1/en active Application Filing
- 2004-08-04 KR KR1020067002512A patent/KR20060057599A/ko not_active Application Discontinuation
- 2004-08-04 AU AU2004263493A patent/AU2004263493A1/en not_active Abandoned
- 2004-08-04 BR BRPI0413384-6A patent/BRPI0413384A/pt not_active IP Right Cessation
- 2004-08-04 TW TW093123372A patent/TW200510384A/zh unknown
- 2004-08-04 AT AT04779960T patent/ATE417041T1/de not_active IP Right Cessation
- 2004-08-04 US US10/911,340 patent/US7557107B2/en not_active Expired - Fee Related
- 2004-08-04 ES ES04779960T patent/ES2317047T3/es active Active
- 2004-08-04 EP EP04779960A patent/EP1660477B1/de active Active
- 2004-08-04 DE DE602004018332T patent/DE602004018332D1/de active Active
- 2004-08-05 PE PE2004000760A patent/PE20050336A1/es not_active Application Discontinuation
- 2004-08-06 AR ARP040102806A patent/AR045447A1/es not_active Application Discontinuation
-
2006
- 2006-02-02 IL IL173514A patent/IL173514A0/en unknown
- 2006-02-06 EC EC2006006349A patent/ECSP066349A/es unknown
- 2006-06-30 HK HK06107445.0A patent/HK1087122A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US20050059672A1 (en) | 2005-03-17 |
BRPI0413384A (pt) | 2006-10-17 |
PE20050336A1 (es) | 2005-05-30 |
JP2007501791A (ja) | 2007-02-01 |
RU2006106768A (ru) | 2007-09-20 |
KR20060057599A (ko) | 2006-05-26 |
AR045447A1 (es) | 2005-10-26 |
WO2005014577A1 (en) | 2005-02-17 |
IL173514A0 (en) | 2006-07-05 |
MXPA06001483A (es) | 2006-05-15 |
CA2535210A1 (en) | 2005-02-17 |
HK1087122A1 (en) | 2006-10-06 |
DE602004018332D1 (de) | 2009-01-22 |
ECSP066349A (es) | 2006-08-30 |
EP1660477A1 (de) | 2006-05-31 |
US7557107B2 (en) | 2009-07-07 |
WO2005014577A9 (en) | 2006-03-23 |
TW200510384A (en) | 2005-03-16 |
ES2317047T3 (es) | 2009-04-16 |
EP1660477B1 (de) | 2008-12-10 |
AU2004263493A1 (en) | 2005-02-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |