ATE411984T1 - Neue kondensierte n-pyrazinyl-sulfonamide und deren verwendung bei der behandlung von chemokinvermittelten krankheiten - Google Patents
Neue kondensierte n-pyrazinyl-sulfonamide und deren verwendung bei der behandlung von chemokinvermittelten krankheitenInfo
- Publication number
- ATE411984T1 ATE411984T1 AT04775333T AT04775333T ATE411984T1 AT E411984 T1 ATE411984 T1 AT E411984T1 AT 04775333 T AT04775333 T AT 04775333T AT 04775333 T AT04775333 T AT 04775333T AT E411984 T1 ATE411984 T1 AT E411984T1
- Authority
- AT
- Austria
- Prior art keywords
- pyrazinyl
- treatment
- chemokine
- sulfonamides
- mediated diseases
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- -1 N-PYRAZINYL SULFONAMIDES Chemical class 0.000 title 1
- 229940124530 sulfonamide Drugs 0.000 title 1
- 102000019034 Chemokines Human genes 0.000 abstract 1
- 108010012236 Chemokines Proteins 0.000 abstract 1
- WFJAYLDZYLZEDQ-UHFFFAOYSA-N O=S(=O)NC1=CN=CC=N1 Chemical class O=S(=O)NC1=CN=CC=N1 WFJAYLDZYLZEDQ-UHFFFAOYSA-N 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
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-
- A—HUMAN NECESSITIES
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- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
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- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
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- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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- A—HUMAN NECESSITIES
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- AIDS & HIV (AREA)
- Otolaryngology (AREA)
- Pain & Pain Management (AREA)
- Ophthalmology & Optometry (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0302304A SE0302304D0 (sv) | 2003-08-27 | 2003-08-27 | Novel compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE411984T1 true ATE411984T1 (de) | 2008-11-15 |
Family
ID=28673200
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04775333T ATE411984T1 (de) | 2003-08-27 | 2004-08-25 | Neue kondensierte n-pyrazinyl-sulfonamide und deren verwendung bei der behandlung von chemokinvermittelten krankheiten |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20070093491A1 (OSRAM) |
| EP (1) | EP1660461B1 (OSRAM) |
| JP (1) | JP2007503432A (OSRAM) |
| AT (1) | ATE411984T1 (OSRAM) |
| DE (1) | DE602004017332D1 (OSRAM) |
| ES (1) | ES2314445T3 (OSRAM) |
| SE (1) | SE0302304D0 (OSRAM) |
| WO (1) | WO2005021513A1 (OSRAM) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI328007B (en) * | 2002-01-16 | 2010-08-01 | Astrazeneca Ab | Novel compounds |
| JPWO2005023771A1 (ja) * | 2003-09-05 | 2006-11-02 | 小野薬品工業株式会社 | ケモカインレセプターアンタゴニストおよびその医薬用途 |
| WO2007044729A2 (en) | 2005-10-07 | 2007-04-19 | Exelixis, Inc. | N- (3-amino-quinoxalin-2-yl) -sulfonamide derivatives and their use as phosphatidylinositol 3-kinase inhibitors |
| EP1790342A1 (de) | 2005-11-11 | 2007-05-30 | Zentaris GmbH | Pyridopyrazin-Derivate und deren Verwendung als Modulatoren der Signaltransduktionswege |
| US8217042B2 (en) | 2005-11-11 | 2012-07-10 | Zentaris Gmbh | Pyridopyrazines and their use as modulators of kinases |
| EP1956009A1 (en) * | 2005-12-02 | 2008-08-13 | Mitsubishi Tanabe Pharma Corporation | Aromatic compound |
| US20090182140A1 (en) * | 2005-12-02 | 2009-07-16 | Mitsubishi Tanabe Pharma Corporation | Alicyclic Heterocyclic Compound |
| TW200730512A (en) * | 2005-12-12 | 2007-08-16 | Astrazeneca Ab | Novel compounds |
| ZA200904857B (en) * | 2007-02-22 | 2010-09-29 | Merck Serono Sa | Quinoxaline compounds and use thereof |
| US7940543B2 (en) * | 2008-03-19 | 2011-05-10 | Nanya Technology Corp. | Low power synchronous memory command address scheme |
| WO2009151910A2 (en) * | 2008-05-25 | 2009-12-17 | Wyeth | Combination product of receptor tyrosine kinase inhibitor and fatty acid synthase inhibitor for treating cancer |
| JP5687903B2 (ja) * | 2008-11-10 | 2015-03-25 | 協和発酵キリン株式会社 | キヌレニン産生抑制剤 |
| TWI535442B (zh) | 2010-05-10 | 2016-06-01 | Kyowa Hakko Kirin Co Ltd | A nitrogen-containing heterocyclic compound having an action of inhibiting the production of canine erythritine |
| CA2815107A1 (en) * | 2010-10-20 | 2012-04-26 | Merck Serono S.A. Geneva | Method for preparing substituted n-(3-amino-quinoxalin-2-yl)-sulfonamides and their intermediates n-(3-chloro-quinoxalin-2-yl)sulfonamides |
| US9067923B2 (en) | 2011-11-09 | 2015-06-30 | Kyowa Hakko Kirin Co., Ltd. | Substituted quinoxalines |
| KR101102377B1 (ko) * | 2011-11-11 | 2012-01-05 | 주식회사 에네스코 | 터빈로터 초음파 탐상용 스캐너 |
| EP4582419A1 (en) * | 2022-08-30 | 2025-07-09 | Kyowa Kirin Co., Ltd. | Method for producing quinoxaline derivative |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1135471B (de) * | 1960-07-30 | 1962-08-30 | Basf Ag | Verfahren zur Herstellung von 3-Chlorchinoxalinderivaten |
| FR1310181A (OSRAM) * | 1960-12-21 | 1963-03-06 | ||
| NL135386C (OSRAM) * | 1966-08-08 | |||
| CS156880B1 (OSRAM) * | 1972-02-09 | 1974-08-23 | ||
| DE3686688T2 (de) * | 1985-06-24 | 1993-03-18 | Merck & Co Inc | Verwendung von sulfanilamido quinoxalinen zur behandlung von neoplastischen krankheiten. |
| US5529999A (en) * | 1994-03-04 | 1996-06-25 | Eli Lilly And Company | Antitumor compositions and methods of treatment |
| AUPN842196A0 (en) * | 1996-03-05 | 1996-03-28 | Fujisawa Pharmaceutical Co., Ltd. | New compound |
| DE60207890T2 (de) * | 2001-12-18 | 2006-08-10 | Astrazeneca Ab | Neue verbindungen |
| TWI328007B (en) * | 2002-01-16 | 2010-08-01 | Astrazeneca Ab | Novel compounds |
| WO2004007472A1 (ja) * | 2002-07-10 | 2004-01-22 | Ono Pharmaceutical Co., Ltd. | Ｃｃｒ４アンタゴニストおよびその医薬用途 |
-
2003
- 2003-08-27 SE SE0302304A patent/SE0302304D0/xx unknown
-
2004
- 2004-08-25 JP JP2006524604A patent/JP2007503432A/ja active Pending
- 2004-08-25 ES ES04775333T patent/ES2314445T3/es not_active Expired - Lifetime
- 2004-08-25 WO PCT/SE2004/001227 patent/WO2005021513A1/en not_active Ceased
- 2004-08-25 AT AT04775333T patent/ATE411984T1/de not_active IP Right Cessation
- 2004-08-25 US US10/570,178 patent/US20070093491A1/en not_active Abandoned
- 2004-08-25 EP EP04775333A patent/EP1660461B1/en not_active Expired - Lifetime
- 2004-08-25 DE DE602004017332T patent/DE602004017332D1/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20070093491A1 (en) | 2007-04-26 |
| DE602004017332D1 (de) | 2008-12-04 |
| EP1660461A1 (en) | 2006-05-31 |
| ES2314445T3 (es) | 2009-03-16 |
| WO2005021513A1 (en) | 2005-03-10 |
| EP1660461B1 (en) | 2008-10-22 |
| SE0302304D0 (sv) | 2003-08-27 |
| JP2007503432A (ja) | 2007-02-22 |
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