DE60310767D1 - PYRAZOL-3,4-d-PYRIMIDINDERIVATE UND IHRE VERWENDUNG BEI DER BEHANDLUNG VON H.PYLORI-INFEKTIONEN - Google Patents

PYRAZOL-3,4-d-PYRIMIDINDERIVATE UND IHRE VERWENDUNG BEI DER BEHANDLUNG VON H.PYLORI-INFEKTIONEN

Info

Publication number
DE60310767D1
DE60310767D1 DE60310767T DE60310767T DE60310767D1 DE 60310767 D1 DE60310767 D1 DE 60310767D1 DE 60310767 T DE60310767 T DE 60310767T DE 60310767 T DE60310767 T DE 60310767T DE 60310767 D1 DE60310767 D1 DE 60310767D1
Authority
DE
Germany
Prior art keywords
treatment
pyrazol
pylori infections
pyrimidin derivatives
pyrimidin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60310767T
Other languages
English (en)
Other versions
DE60310767T2 (de
Inventor
Gregory Basarab
Joseph Eyermann
Madhusudhan Govravaram
Oluyinka Green
Lawrence Macpherson
Marshall Morningstar
Thanh Nguyen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Application granted granted Critical
Publication of DE60310767D1 publication Critical patent/DE60310767D1/de
Publication of DE60310767T2 publication Critical patent/DE60310767T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
DE60310767T 2002-12-20 2003-12-19 PYRAZOL-3,4-d-PYRIMIDINDERIVATE UND IHRE VERWENDUNG BEI DER BEHANDLUNG VON H.PYLORI-INFEKTIONEN Expired - Fee Related DE60310767T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0203825A SE0203825D0 (sv) 2002-12-20 2002-12-20 Novel fused heterocycles and uses thereof
SE0203825 2002-12-20
PCT/SE2003/002033 WO2004056831A1 (en) 2002-12-20 2003-12-19 PYRAZOLO [3,4-d] PYRIMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF H.PYLORI INFECTION

Publications (2)

Publication Number Publication Date
DE60310767D1 true DE60310767D1 (de) 2007-02-08
DE60310767T2 DE60310767T2 (de) 2007-10-11

Family

ID=20289974

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60310767T Expired - Fee Related DE60310767T2 (de) 2002-12-20 2003-12-19 PYRAZOL-3,4-d-PYRIMIDINDERIVATE UND IHRE VERWENDUNG BEI DER BEHANDLUNG VON H.PYLORI-INFEKTIONEN

Country Status (9)

Country Link
US (1) US20070004761A1 (de)
EP (1) EP1585748B1 (de)
JP (1) JP2006512366A (de)
AT (1) ATE349448T1 (de)
AU (1) AU2003288869A1 (de)
DE (1) DE60310767T2 (de)
ES (1) ES2278211T3 (de)
SE (1) SE0203825D0 (de)
WO (1) WO2004056831A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2459161A1 (en) 2001-08-31 2003-03-13 The Rockefeller University Phosphodiesterase activity and regulation of phosphodiesterase 1b-mediated signaling in brain
AU2007256633B2 (en) 2006-06-06 2013-09-12 Intra-Cellular Therapies, Inc. Organic compounds
EP2081431B1 (de) 2006-11-13 2013-01-16 Intra-Cellular Therapies, Inc. Organische verbindungen
CA2707218A1 (en) 2007-12-06 2009-06-11 Intra-Cellular Therapies, Inc. Organic compounds
CA2722923C (en) 2008-04-29 2016-08-02 Boehringer Ingelheim International Gmbh Indazole compounds as ccr1 receptor antagonists
US8293917B2 (en) * 2008-05-06 2012-10-23 Boehringer Ingelheim International Gmbh Pyrazole compounds as CCR1 antagonists
NZ591115A (en) 2008-09-26 2012-10-26 Boehringer Ingelheim Int Azaindazole compounds as ccr1 receptor antagonists
CA2740385A1 (en) 2008-12-06 2010-06-10 Intra-Cellular Therapies, Inc. Organic compounds
MX2011005932A (es) 2008-12-06 2011-12-16 Intra Cellular Therapies Inc Compuestos organicos.
EA201170772A1 (ru) 2008-12-06 2012-03-30 Интра-Селлулар Терапиз, Инк. Органические соединения
WO2011016861A2 (en) 2009-08-05 2011-02-10 Intra-Cellular Therapies, Inc. Novel regulatory proteins and inhibitors
CA2778060A1 (en) 2009-10-21 2011-04-28 Boehringer Ingelheim International Gmbh Indazole and pyrazolopyridine compounds as ccr1 receptor antagonists
JP5542214B2 (ja) 2009-10-27 2014-07-09 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｃｃｒ１受容体アンタゴニストとしての複素環化合物
MX2012006524A (es) * 2009-12-08 2012-07-17 Boehringer Ingelheim Int Proceso para la sintesis de compuestos intermedios de utilidad para preparar compuestos sustituidos de indazol y azaindol.
WO2011137109A1 (en) 2010-04-30 2011-11-03 Boehringer Ingelheim International Gmbh Azaindazole amide compounds as ccr1 receptor antagonists
WO2011153136A1 (en) 2010-05-31 2011-12-08 Intra-Cellular Therapies, Inc. Organic compounds
US9371327B2 (en) 2010-05-31 2016-06-21 Intra-Cellular Therapies, Inc. PDE1 inhibitor compounds
US8546442B2 (en) 2010-12-23 2013-10-01 Boehringer Ingelheim International Gmbh Pyrazolopiperidine compounds as CCR1 receptor antagonists
US9546175B2 (en) 2014-08-07 2017-01-17 Intra-Cellular Therapies, Inc. Organic compounds
CN112533923A (zh) 2018-06-04 2021-03-19 爱克思科技有限公司 作为腺苷受体拮抗剂的吡唑并嘧啶化合物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3839839A1 (de) * 1988-11-25 1990-05-31 Henning Berlin Gmbh Mittel zur behandlung von chronisch entzuendlichen darmerkrankungen
SE0102315D0 (sv) * 2001-06-28 2001-06-28 Astrazeneca Ab Compounds

Also Published As

Publication number Publication date
AU2003288869A1 (en) 2004-07-14
US20070004761A1 (en) 2007-01-04
WO2004056831A1 (en) 2004-07-08
ES2278211T3 (es) 2007-08-01
EP1585748B1 (de) 2006-12-27
DE60310767T2 (de) 2007-10-11
JP2006512366A (ja) 2006-04-13
SE0203825D0 (sv) 2002-12-20
ATE349448T1 (de) 2007-01-15
EP1585748A1 (de) 2005-10-19

Similar Documents

Publication Publication Date Title
DE60310767D1 (de) PYRAZOL-3,4-d-PYRIMIDINDERIVATE UND IHRE VERWENDUNG BEI DER BEHANDLUNG VON H.PYLORI-INFEKTIONEN
SE0102315D0 (sv) Compounds
MX2007000505A (es) Derivados de oxindol sustituidos y medicamentos que contienen los mismos.
NO20054083L (no) Nye sammenkoblede triazoloner og deres anvendelse
EA201000643A1 (ru) Замещенное производное этилендиамина для лечения микобактериальных заболеваний и фармацевтическая композиция на его основе
NO20025601L (no) Arylmetylaminderivater for anvendelse som tryptaseinhibitorer
NO20063479L (no) Fosfonater, monofosfonamidater og bis-fosfonamidater for behandling av virussykdommer
NO20045247L (no) Nukleosidderivater for behandling av hepatitt C-virusinfeksjon
WO2006100081A3 (de) Substituierte oxindol-derivate, diese enthaltende arzneimittel und deren verwendung
PL372809A1 (en) Substituted 1,3-diphenylprop-2-en-1-one derivatives and preparation and uses thereof
ATE478044T1 (de) Biphenylderivate und ihre verwendung bei der behandlung von hepatitis c
ECSP044992A (es) Inhibidores de la alquín-aril fosfodiesterasa-4
DE60214179D1 (de) IMIDAZOi1,2-AöPYRIDIN-DERIVATE ZUR PROPHYLAXE UND BEHANDLUNG VON HERPES-INFEKTIONEN
ATE433447T1 (de) Pyrimiidinverbindungen
NO20050828L (no) lndol-3-svovelderivater
DK1200418T3 (da) Nematodicide trifluorbutener
DE60003863D1 (de) Dioxocyclopentylhydroxamsäure
ATE423122T1 (de) Kondensierte heterocyclen als inhibitoren von glutamatracemase (muri)
WO2006072458A3 (de) Substituierte oxindol-derivate, diese enthaltende arzneimittel und deren verwendung
ECSP055844A (es) Nuevos compuestos triciclicos
DE60211539D1 (de) Imidazopyridinderivate zur verwendung bei der behandlung von herpes-vireninfektion
NO20051844L (no) Piperazinderivater og fremgangsmate for anvendelse derav.
NO20043016L (no) 6-aminomorfinan-derivater, fremgangsmate for fremstilling og anvendelse derav
NO20044549L (no) Bisykliske 6-alkaliden-penemer som beta-laktamaseinhibitorer
NO20044550L (no) Heterotrisyklyl 6-alkaliden-penemer som beta-laktamaseinhibitorer

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee