DE60207890D1 - Neue verbindungen - Google Patents

Neue verbindungen

Info

Publication number
DE60207890D1
DE60207890D1 DE60207890T DE60207890T DE60207890D1 DE 60207890 D1 DE60207890 D1 DE 60207890D1 DE 60207890 T DE60207890 T DE 60207890T DE 60207890 T DE60207890 T DE 60207890T DE 60207890 D1 DE60207890 D1 DE 60207890D1
Authority
DE
Germany
Prior art keywords
new connections
thienylsulphonamides
pyrazinyl
asthma
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60207890T
Other languages
English (en)
Other versions
DE60207890T2 (de
Inventor
Andrew Baxter
Timothy Johnson
Nicholas Kindon
Bryan Roberts
John Steele
Michael Stocks
Nicholas Tomkinson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE0104474A external-priority patent/SE0104474D0/xx
Priority claimed from SE0202139A external-priority patent/SE0202139D0/xx
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Application granted granted Critical
Publication of DE60207890D1 publication Critical patent/DE60207890D1/de
Publication of DE60207890T2 publication Critical patent/DE60207890T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
DE60207890T 2001-12-18 2002-12-17 Neue verbindungen Expired - Fee Related DE60207890T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
SE0104474 2001-12-18
SE0104474A SE0104474D0 (sv) 2001-12-18 2001-12-18 Novel Compounds
SE0202139 2002-07-05
SE0202139A SE0202139D0 (sv) 2002-07-05 2002-07-05 Novel compounds
PCT/SE2002/002355 WO2003051870A1 (en) 2001-12-18 2002-12-17 Novel compounds

Publications (2)

Publication Number Publication Date
DE60207890D1 true DE60207890D1 (de) 2006-01-12
DE60207890T2 DE60207890T2 (de) 2006-08-10

Family

ID=26655646

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60207890T Expired - Fee Related DE60207890T2 (de) 2001-12-18 2002-12-17 Neue verbindungen

Country Status (7)

Country Link
US (1) US7410972B2 (de)
EP (1) EP1458715B1 (de)
JP (1) JP2005516936A (de)
AT (1) ATE312096T1 (de)
AU (1) AU2002358390A1 (de)
DE (1) DE60207890T2 (de)
WO (1) WO2003051870A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI328007B (en) * 2002-01-16 2010-08-01 Astrazeneca Ab Novel compounds
DE10260003A1 (de) * 2002-12-20 2004-07-08 Zf Friedrichshafen Ag Radnabenantrieb
SE0301653D0 (sv) * 2003-06-05 2003-06-05 Astrazeneca Ab Novel compounds
SE0302304D0 (sv) * 2003-08-27 2003-08-27 Astrazeneca Ab Novel compounds
WO2005023771A1 (ja) * 2003-09-05 2005-03-17 Ono Pharmaceutical Co., Ltd. ケモカインレセプターアンタゴニストおよびその医薬用途
MX2007007797A (es) * 2004-12-27 2007-08-23 Alcon Inc Analogo de aminopirazina para tratar glaucoma y otras enfermedades mediadas por rho cinasa.
CA2594726C (en) * 2005-01-14 2013-03-19 Chemocentryx, Inc. Heteroaryl sulfonamides and ccr2
US7622583B2 (en) 2005-01-14 2009-11-24 Chemocentryx, Inc. Heteroaryl sulfonamides and CCR2
BRPI0607308A2 (pt) 2005-01-25 2009-08-25 Synta Pharmaceuticals Corp compostos, composições farmacêuticas e usos dos referidos compostos
GB0514743D0 (en) * 2005-07-19 2005-08-24 Astrazeneca Ab Salt
TW200800921A (en) * 2005-09-19 2008-01-01 Astrazeneca Ab Novel compounds
EP1956009A1 (de) * 2005-12-02 2008-08-13 Mitsubishi Tanabe Pharma Corporation Aromatische verbindung
WO2007063934A1 (ja) * 2005-12-02 2007-06-07 Mitsubishi Tanabe Pharma Corporation 脂環式複素環化合物
TW200730512A (en) 2005-12-12 2007-08-16 Astrazeneca Ab Novel compounds
GB0526445D0 (en) * 2005-12-23 2006-02-08 Novartis Ag Organic compounds
AU2008219297B2 (en) * 2007-02-22 2013-07-04 Merck Serono S.A. Quinoxaline compounds and use thereof
KR101849560B1 (ko) 2007-07-12 2018-04-17 케모센트릭스, 인크. 염증의 치료를 위한 ccr2 조절물질로서 융합된 헤테로아릴 피리딜과 페닐 벤젠술폰아마이드
JP5687903B2 (ja) 2008-11-10 2015-03-25 協和発酵キリン株式会社 キヌレニン産生抑制剤
TWI535442B (zh) 2010-05-10 2016-06-01 Kyowa Hakko Kirin Co Ltd A nitrogen-containing heterocyclic compound having an action of inhibiting the production of canine erythritine
WO2012052420A1 (en) 2010-10-20 2012-04-26 Merck Serono S.A. Geneva Method for preparing substituted n-(3-amino-quinoxalin-2-yl)-sulfonamides and their intermediates n-(3-chloro-quinoxalin-2-yl)sulfonamides
WO2013069765A1 (ja) 2011-11-09 2013-05-16 協和発酵キリン株式会社 含窒素複素環化合物
JP6322280B2 (ja) * 2013-05-14 2018-05-09 アクティブ バイオテック エイビー S−100阻害薬として有用なn−(ヘテロアリール)スルホンアミド誘導体
RU2765737C2 (ru) 2016-11-23 2022-02-02 Хемоцентрикс, Инк. Способ лечения фокально-сегментарного гломерулосклероза
US10758540B2 (en) 2017-10-11 2020-09-01 Chemocentryx, Inc. Treatment of focal segmental glomerulosclerosis with CCR2 antagonists

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5962490A (en) * 1987-09-25 1999-10-05 Texas Biotechnology Corporation Thienyl-, furyl- and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin
CA2162630C (en) * 1994-11-25 2007-05-01 Volker Breu Sulfonamides
US20060004010A1 (en) 2002-07-10 2006-01-05 Hiromu Habashita Ccr4 antagonist and medical use thereof

Also Published As

Publication number Publication date
EP1458715A1 (de) 2004-09-22
DE60207890T2 (de) 2006-08-10
US7410972B2 (en) 2008-08-12
WO2003051870A1 (en) 2003-06-26
ATE312096T1 (de) 2005-12-15
JP2005516936A (ja) 2005-06-09
EP1458715B1 (de) 2005-12-07
AU2002358390A1 (en) 2003-06-30
US20050075346A1 (en) 2005-04-07

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee