ATE408017T1 - Verfahren zur rna und protein synthese - Google Patents
Verfahren zur rna und protein syntheseInfo
- Publication number
- ATE408017T1 ATE408017T1 AT02764858T AT02764858T ATE408017T1 AT E408017 T1 ATE408017 T1 AT E408017T1 AT 02764858 T AT02764858 T AT 02764858T AT 02764858 T AT02764858 T AT 02764858T AT E408017 T1 ATE408017 T1 AT E408017T1
- Authority
- AT
- Austria
- Prior art keywords
- rna
- protein synthesis
- cellular
- cell
- present
- Prior art date
Links
- 230000006819 RNA synthesis Effects 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 238000001243 protein synthesis Methods 0.000 title abstract 3
- 230000014616 translation Effects 0.000 title abstract 3
- 210000004671 cell-free system Anatomy 0.000 abstract 2
- 230000001413 cellular effect Effects 0.000 abstract 2
- 102000004163 DNA-directed RNA polymerases Human genes 0.000 abstract 1
- 108090000626 DNA-directed RNA polymerases Proteins 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
- C12N9/1247—DNA-directed RNA polymerase (2.7.7.6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01402049A EP1279736A1 (en) | 2001-07-27 | 2001-07-27 | Methods of RNA and protein synthesis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE408017T1 true ATE408017T1 (de) | 2008-09-15 |
Family
ID=8182831
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02764858T ATE408017T1 (de) | 2001-07-27 | 2002-07-26 | Verfahren zur rna und protein synthese |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7186525B2 (https=) |
| EP (2) | EP1279736A1 (https=) |
| AT (1) | ATE408017T1 (https=) |
| AU (1) | AU2002329256A1 (https=) |
| DE (1) | DE60228847D1 (https=) |
| WO (1) | WO2003012114A2 (https=) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100447530B1 (ko) * | 2001-08-14 | 2004-09-08 | 한국과학기술원 | ＯｍｐＦ를 이용하여 목적 단백질을 대장균 세포외로분비생산하는 방법 |
| US20060084136A1 (en) * | 2004-07-14 | 2006-04-20 | Invitrogen Corporation | Production of fusion proteins by cell-free protein synthesis |
| US20080248565A1 (en) * | 2007-03-01 | 2008-10-09 | Invitrogen Corporation | Isolated phospholipid-protein particles |
| US20070117179A1 (en) * | 2005-09-27 | 2007-05-24 | Invitrogen Corporation | In vitro protein synthesis systems for membrane proteins that include adolipoproteins and phospholipid-adolipoprotein particles |
| WO2007037301A1 (ja) * | 2005-09-29 | 2007-04-05 | Kyowa Hakko Kogyo Co., Ltd. | 有用物質の製造法 |
| EP3121286B1 (en) | 2006-12-21 | 2019-11-20 | Gen-Probe Incorporated | Methods and compositions for nucleic acid amplification |
| EP2449132B1 (en) | 2009-07-01 | 2015-05-13 | Gen-Probe Incorporated | Methods and compositions for nucleic acid amplification |
| CA2809284C (en) | 2010-08-31 | 2021-02-23 | Greenlight Biosciences, Inc. | Methods for control of flux in metabolic pathways through protease manipulation |
| DK2890814T3 (da) | 2012-08-30 | 2019-12-16 | Gen Probe Inc | Flerfaset nukleinsyreamplificering |
| BR112016002494A2 (pt) | 2013-08-05 | 2017-09-05 | Greenlight Biosciences Inc | Proteí-nas construídas com um sítio de clivagem de protease, ácido nucléico, vetor, célula e processo de engenharia de uma proteína recombinante e de um grande número de variantes de ácidos nucleicos que codificam proteínas recombinantes |
| WO2016005982A1 (en) * | 2014-07-08 | 2016-01-14 | Technion Research & Development Foundation Limited | Methods and kits for cell-free transcription and translation |
| KR20180002636A (ko) | 2015-03-30 | 2018-01-08 | 그린라이트 바이오사이언시스, 아이엔씨. | 리보핵산의 무세포 생산 |
| CN107849573B (zh) * | 2015-04-30 | 2023-04-14 | 恩格内斯生物科技有限公司 | 生长和蛋白质生产的解偶联 |
| CR20180525A (es) | 2016-04-06 | 2019-02-14 | Greenlight Biosciences Inc | Producción de ácido ribonucleico libre de células |
| US12227778B2 (en) | 2016-12-30 | 2025-02-18 | Nature's Toolbox, Inc. | Cell-free expression system having novel inorganic polyphosphate-based energy regeneration |
| WO2018126287A1 (en) * | 2016-12-30 | 2018-07-05 | Ntxbio, Llc | Cell-free expression system having novel inorganic polyphosphate-based energy regeneration |
| US20200181670A1 (en) * | 2017-08-11 | 2020-06-11 | Synvitrobio, Inc. | Improved In Vitro Transcription/Translation (TXTL) System and Use Thereof |
| BR112020007068A2 (pt) | 2017-10-11 | 2020-10-06 | Greenlight Biosciences, Inc. | métodos e composições para produção de nucleosídeo trifosfato e ácido ribonucleico |
| US11673921B2 (en) | 2017-11-10 | 2023-06-13 | Northwestern University | Cell-free protein synthesis platform derived from cellular extracts of Vibrio natriegens |
| US11814621B2 (en) | 2018-06-01 | 2023-11-14 | Northwestern University | Expanding the chemical substrates for genetic code reprogramming |
| WO2020010356A1 (en) | 2018-07-06 | 2020-01-09 | Northwestern University | Ribosome variants for sequence defined polymer synthesis |
| US12098433B2 (en) | 2018-08-03 | 2024-09-24 | Northwestern University | On demand, portable, cell-free molecular sensing platform |
| CA3131243A1 (en) | 2019-02-25 | 2020-09-03 | Northwestern University | Cell-free protein synthesis platforms derived from clostridia |
| KR20210151928A (ko) * | 2019-04-12 | 2021-12-14 | 네이쳐스 툴박스 인코포레이티드 | 호열성 단백질을 이용한 재조합 시험관내 전사 및 해독을 위한 시스템, 방법 및 조성물 |
| BR112022002365A2 (pt) | 2019-08-09 | 2022-04-26 | Nutcracker Therapeutics Inc | Métodos e aparelhos para fabricar e para remover material de uma composição terapêutica |
| WO2024120767A1 (en) * | 2022-12-05 | 2024-06-13 | Novozymes A/S | Modified rna polymerase activities |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU7625298A (en) * | 1996-12-03 | 1998-06-29 | Scriptgen Pharmaceuticals, Inc. | M. tuberculosis RNA polymerase alpha subunit |
| AU4241400A (en) * | 1999-04-16 | 2000-11-02 | Board Of Trustees Of The University Of Arkansas, The | Agrobacterium tumefaciens rpoa gene |
-
2001
- 2001-07-27 EP EP01402049A patent/EP1279736A1/en not_active Withdrawn
-
2002
- 2002-07-26 AU AU2002329256A patent/AU2002329256A1/en not_active Abandoned
- 2002-07-26 AT AT02764858T patent/ATE408017T1/de not_active IP Right Cessation
- 2002-07-26 DE DE60228847T patent/DE60228847D1/de not_active Expired - Lifetime
- 2002-07-26 EP EP02764858A patent/EP1412504B1/en not_active Expired - Lifetime
- 2002-07-26 WO PCT/EP2002/009423 patent/WO2003012114A2/en not_active Ceased
-
2004
- 2004-01-27 US US10/764,581 patent/US7186525B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US7186525B2 (en) | 2007-03-06 |
| DE60228847D1 (https=) | 2008-10-23 |
| AU2002329256A1 (en) | 2003-02-17 |
| US20050032086A1 (en) | 2005-02-10 |
| WO2003012114A2 (en) | 2003-02-13 |
| WO2003012114A3 (en) | 2003-08-28 |
| EP1279736A1 (en) | 2003-01-29 |
| EP1412504A2 (en) | 2004-04-28 |
| EP1412504B1 (en) | 2008-09-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |