ATE408017T1 - Verfahren zur rna und protein synthese - Google Patents
Verfahren zur rna und protein syntheseInfo
- Publication number
- ATE408017T1 ATE408017T1 AT02764858T AT02764858T ATE408017T1 AT E408017 T1 ATE408017 T1 AT E408017T1 AT 02764858 T AT02764858 T AT 02764858T AT 02764858 T AT02764858 T AT 02764858T AT E408017 T1 ATE408017 T1 AT E408017T1
- Authority
- AT
- Austria
- Prior art keywords
- rna
- protein synthesis
- cellular
- cell
- present
- Prior art date
Links
- 230000006819 RNA synthesis Effects 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 238000001243 protein synthesis Methods 0.000 title abstract 3
- 230000014616 translation Effects 0.000 title abstract 3
- 210000004671 cell-free system Anatomy 0.000 abstract 2
- 230000001413 cellular effect Effects 0.000 abstract 2
- 102000004163 DNA-directed RNA polymerases Human genes 0.000 abstract 1
- 108090000626 DNA-directed RNA polymerases Proteins 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
- C12N9/1247—DNA-directed RNA polymerase (2.7.7.6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01402049A EP1279736A1 (de) | 2001-07-27 | 2001-07-27 | Verfahren zur RNA und Protein Synthese |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE408017T1 true ATE408017T1 (de) | 2008-09-15 |
Family
ID=8182831
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02764858T ATE408017T1 (de) | 2001-07-27 | 2002-07-26 | Verfahren zur rna und protein synthese |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7186525B2 (de) |
| EP (2) | EP1279736A1 (de) |
| AT (1) | ATE408017T1 (de) |
| AU (1) | AU2002329256A1 (de) |
| DE (1) | DE60228847D1 (de) |
| WO (1) | WO2003012114A2 (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100447530B1 (ko) * | 2001-08-14 | 2004-09-08 | 한국과학기술원 | ＯｍｐＦ를 이용하여 목적 단백질을 대장균 세포외로분비생산하는 방법 |
| WO2006019876A2 (en) * | 2004-07-14 | 2006-02-23 | Invitrogen Corporation | Production of fusion proteins by cell-free protein synthesis |
| US20080248565A1 (en) * | 2007-03-01 | 2008-10-09 | Invitrogen Corporation | Isolated phospholipid-protein particles |
| US20070117179A1 (en) * | 2005-09-27 | 2007-05-24 | Invitrogen Corporation | In vitro protein synthesis systems for membrane proteins that include adolipoproteins and phospholipid-adolipoprotein particles |
| US20100047861A1 (en) * | 2005-09-29 | 2010-02-25 | Kiyotaka Hara | Process for producing useful substance |
| CA2673017C (en) | 2006-12-21 | 2015-08-04 | Gen-Probe Incorporated | Methods and compositions for nucleic acid amplification |
| AU2010266234B2 (en) | 2009-07-01 | 2013-07-25 | Gen-Probe Incorporated | Methods and compositions for nucleic acid amplification |
| US8916358B2 (en) | 2010-08-31 | 2014-12-23 | Greenlight Biosciences, Inc. | Methods for control of flux in metabolic pathways through protease manipulation |
| EP2890814B1 (de) | 2012-08-30 | 2019-11-13 | Gen-Probe Incorporated | Mehrphasige nukleinsäureamplifikation |
| WO2015021058A2 (en) | 2013-08-05 | 2015-02-12 | Greenlight Biosciences, Inc. | Engineered proteins with a protease cleavage site |
| EP3167072A4 (de) * | 2014-07-08 | 2018-04-18 | Technion Research & Development Foundation Ltd. | Verfahren und kits zur zellfreien transkription und translation |
| BR112017020690A2 (pt) * | 2015-03-30 | 2018-06-26 | Greenlight Biosciences Inc | produção livre de células de ácido ribonucleico |
| KR102751873B1 (ko) * | 2015-04-30 | 2025-01-09 | 엔진스 바이오테크 게엠베하 | 성장 및 단백질 생성의 탈결합 |
| SG11201808721YA (en) * | 2016-04-06 | 2018-11-29 | Greenlight Biosciences Inc | Cell-free production of ribonucleic acid |
| WO2018126287A1 (en) * | 2016-12-30 | 2018-07-05 | Ntxbio, Llc | Cell-free expression system having novel inorganic polyphosphate-based energy regeneration |
| US12227778B2 (en) | 2016-12-30 | 2025-02-18 | Nature's Toolbox, Inc. | Cell-free expression system having novel inorganic polyphosphate-based energy regeneration |
| EP3665188A4 (de) * | 2017-08-11 | 2021-07-21 | Synvitrobio, Inc. | Verbessertes in-vitro-transkriptions-/translationssystem (txtl) und seine verwendung |
| JP7792196B2 (ja) | 2017-10-11 | 2025-12-25 | グリーンライト バイオサイエンシーズ インコーポレーテッド | ヌクレオシド三リン酸およびリボ核酸の生成のための方法および組成物 |
| WO2019094859A1 (en) | 2017-11-10 | 2019-05-16 | Northwestern University | Cell-free protein synthesis platform derived from cellular extracts of vibrio natriegens |
| US11814621B2 (en) | 2018-06-01 | 2023-11-14 | Northwestern University | Expanding the chemical substrates for genetic code reprogramming |
| US12421537B2 (en) | 2018-07-06 | 2025-09-23 | Northwestern University | Ribosome variants for sequence defined polymer synthesis |
| WO2020072127A2 (en) | 2018-08-03 | 2020-04-09 | Northwestern University | On demand, portable, cell-free molecular sensing platform |
| CN113490748A (zh) | 2019-02-25 | 2021-10-08 | 西北大学 | 来源于梭菌属提取物的无细胞蛋白质合成平台 |
| US20220275028A1 (en) * | 2019-04-12 | 2022-09-01 | Nature's Toolbox, Inc. | Systems, Methods And Compositions For Recombinant In Vitro Transcription And Translation Utilizing Thermophilic Proteins |
| US11926817B2 (en) | 2019-08-09 | 2024-03-12 | Nutcracker Therapeutics, Inc. | Microfluidic apparatus and methods of use thereof |
| EP4630563A1 (de) * | 2022-12-05 | 2025-10-15 | Novozymes A/S | Modifizierte rna-polymeraseaktivitäten |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU7625298A (en) * | 1996-12-03 | 1998-06-29 | Scriptgen Pharmaceuticals, Inc. | M. tuberculosis RNA polymerase alpha subunit |
| AU4241400A (en) * | 1999-04-16 | 2000-11-02 | Board Of Trustees Of The University Of Arkansas, The | Agrobacterium tumefaciens rpoa gene |
-
2001
- 2001-07-27 EP EP01402049A patent/EP1279736A1/de not_active Withdrawn
-
2002
- 2002-07-26 DE DE60228847T patent/DE60228847D1/de not_active Expired - Lifetime
- 2002-07-26 AU AU2002329256A patent/AU2002329256A1/en not_active Abandoned
- 2002-07-26 EP EP02764858A patent/EP1412504B1/de not_active Expired - Lifetime
- 2002-07-26 AT AT02764858T patent/ATE408017T1/de not_active IP Right Cessation
- 2002-07-26 WO PCT/EP2002/009423 patent/WO2003012114A2/en not_active Ceased
-
2004
- 2004-01-27 US US10/764,581 patent/US7186525B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1412504B1 (de) | 2008-09-10 |
| WO2003012114A2 (en) | 2003-02-13 |
| EP1412504A2 (de) | 2004-04-28 |
| DE60228847D1 (de) | 2008-10-23 |
| US7186525B2 (en) | 2007-03-06 |
| EP1279736A1 (de) | 2003-01-29 |
| WO2003012114A3 (en) | 2003-08-28 |
| AU2002329256A1 (en) | 2003-02-17 |
| US20050032086A1 (en) | 2005-02-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE60228847D1 (de) | ||
| DE602004031134D1 (de) | Pharmazeutische zusammensetzungen und verfahren zur verwendung von levodopa und carbidopa | |
| WO2005084116A3 (en) | Calcium channel variants | |
| ATE407138T1 (de) | Verfahren zur herstellung interferierender rna- moleküle in säugetierzellen und therapeutische anwendungen solcher moleküle | |
| PT1913001E (pt) | (r)-n-metilnaltrexona, processos para a sua síntese e sua utilização farmacêutica | |
| ATE485366T1 (de) | Verwendung von lysyloxydase inhibitoren zur zellkultur und gewebeaufbau | |
| DE602004014117D1 (de) | Thiazole zur verwendung als inhibitoren von protein-kinasen | |
| ATE404587T1 (de) | Verfahren zur identifizierung von induktoren und inhibitoren proteolytischer antikörper, zusammensetzungen sowie deren verwendungen | |
| ATE408624T1 (de) | Verfahren zur reinigung von fsh | |
| DE60232083D1 (de) | Expansionskulturverfahren für antigenspezifische zytotoxische t-lymphozyten | |
| ATE449104T1 (de) | Verfahren zur reinigung von fibrinogen | |
| ATE278785T1 (de) | Neues verfahren zur gewinnung und reinigung von fusionsproteinen | |
| ATE344321T1 (de) | Verfahren zur aufreinigung von bakterienzellen und zellbestandteilen | |
| DE60225312D1 (de) | Samenspezifische 7s-alpha-promoter zur expression von genen in pflanzen | |
| DE60322727D1 (de) | Rückgefaltetes Membranprotein in monodisperser Form | |
| DE602004015421D1 (de) | Elastische befestigungslasche, befestigungssystem und verfahren zur herstellung davon | |
| ATE402198T1 (de) | Verfahren zur immobilisierung biologischer moleküle an feste oberflächen | |
| DE60210778D1 (de) | Verfahren zur herstellung von 4-amino-2,5-bisheterocyclylchinazolinen | |
| ATE325794T1 (de) | Verfahren zur herstellung und zwischenprodukte von pyridin-2-yl-amin | |
| DE50211253D1 (de) | Verfahren zur Herstellung von Makrokapseln | |
| ATE392413T1 (de) | Verfahren zur herstellung von beta-alaninamiden | |
| BR0001906A (pt) | Processo para a preparação fermentativa de l-aminoácidos usando bactérias corineformes | |
| ATE339523T1 (de) | Verfahren zur herstellung von rekombinanten nukleinsäuremolekülen | |
| DE60325737D1 (de) | Verfahren und zusammensetzungen zum targeting sekretorischer lysosomen | |
| ATE402948T1 (de) | Verfahren zur aufreinigung eines nichtimmunoglobulinproteins, das eine immunoglobulinähnliche (ig-like) domäne enthält |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |