ATE408017T1 - Verfahren zur rna und protein synthese - Google Patents
Verfahren zur rna und protein syntheseInfo
- Publication number
- ATE408017T1 ATE408017T1 AT02764858T AT02764858T ATE408017T1 AT E408017 T1 ATE408017 T1 AT E408017T1 AT 02764858 T AT02764858 T AT 02764858T AT 02764858 T AT02764858 T AT 02764858T AT E408017 T1 ATE408017 T1 AT E408017T1
- Authority
- AT
- Austria
- Prior art keywords
- rna
- protein synthesis
- cellular
- cell
- present
- Prior art date
Links
- 230000006819 RNA synthesis Effects 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 238000001243 protein synthesis Methods 0.000 title abstract 3
- 230000014616 translation Effects 0.000 title abstract 3
- 210000004671 cell-free system Anatomy 0.000 abstract 2
- 230000001413 cellular effect Effects 0.000 abstract 2
- 102000004163 DNA-directed RNA polymerases Human genes 0.000 abstract 1
- 108090000626 DNA-directed RNA polymerases Proteins 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
- C12N9/1247—DNA-directed RNA polymerase (2.7.7.6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01402049A EP1279736A1 (de) | 2001-07-27 | 2001-07-27 | Verfahren zur RNA und Protein Synthese |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE408017T1 true ATE408017T1 (de) | 2008-09-15 |
Family
ID=8182831
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02764858T ATE408017T1 (de) | 2001-07-27 | 2002-07-26 | Verfahren zur rna und protein synthese |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7186525B2 (de) |
| EP (2) | EP1279736A1 (de) |
| AT (1) | ATE408017T1 (de) |
| AU (1) | AU2002329256A1 (de) |
| DE (1) | DE60228847D1 (de) |
| WO (1) | WO2003012114A2 (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100447530B1 (ko) * | 2001-08-14 | 2004-09-08 | 한국과학기술원 | OmpF를 이용하여 목적 단백질을 대장균 세포외로분비생산하는 방법 |
| US20060084136A1 (en) * | 2004-07-14 | 2006-04-20 | Invitrogen Corporation | Production of fusion proteins by cell-free protein synthesis |
| US20070117179A1 (en) * | 2005-09-27 | 2007-05-24 | Invitrogen Corporation | In vitro protein synthesis systems for membrane proteins that include adolipoproteins and phospholipid-adolipoprotein particles |
| US20080248565A1 (en) * | 2007-03-01 | 2008-10-09 | Invitrogen Corporation | Isolated phospholipid-protein particles |
| JPWO2007037301A1 (ja) * | 2005-09-29 | 2009-04-09 | 協和発酵キリン株式会社 | 有用物質の製造法 |
| US8198027B2 (en) | 2006-12-21 | 2012-06-12 | Gen-Probe Incorporated | Methods and compositions for nucleic acid amplification |
| EP2449132B1 (de) | 2009-07-01 | 2015-05-13 | Gen-Probe Incorporated | Verfahren und zusammensetzungen zur erweiterung von nukleinsäuren |
| US8916358B2 (en) | 2010-08-31 | 2014-12-23 | Greenlight Biosciences, Inc. | Methods for control of flux in metabolic pathways through protease manipulation |
| ES2761920T3 (es) | 2012-08-30 | 2020-05-21 | Gen Probe Inc | Amplificación de ácido nucleico multifásica |
| JP6483687B2 (ja) | 2013-08-05 | 2019-03-13 | グリーンライト バイオサイエンシーズ インコーポレーテッドGreenlight Biosciences,Inc. | プロテアーゼ切断部位を有する操作されたタンパク質 |
| EP3167072A4 (de) * | 2014-07-08 | 2018-04-18 | Technion Research & Development Foundation Ltd. | Verfahren und kits zur zellfreien transkription und translation |
| BR112017020690A2 (pt) * | 2015-03-30 | 2018-06-26 | Greenlight Biosciences Inc | produção livre de células de ácido ribonucleico |
| CA2983894C (en) * | 2015-04-30 | 2023-09-19 | Engenes Biotech Gmbh | Uncoupling growth and protein production |
| CN109196109B (zh) * | 2016-04-06 | 2024-06-25 | 绿光生物科技股份有限公司 | 无细胞生成核糖核酸 |
| US12227778B2 (en) | 2016-12-30 | 2025-02-18 | Nature's Toolbox, Inc. | Cell-free expression system having novel inorganic polyphosphate-based energy regeneration |
| DK3562940T3 (da) * | 2016-12-30 | 2022-07-11 | Natures Toolbox Inc | Cellefrit ekspressionssystem med hidtil ukendt, uorganisk polyphosphatbaseret energiregeneration |
| US20200181670A1 (en) * | 2017-08-11 | 2020-06-11 | Synvitrobio, Inc. | Improved In Vitro Transcription/Translation (TXTL) System and Use Thereof |
| BR112020007068A2 (pt) | 2017-10-11 | 2020-10-06 | Greenlight Biosciences, Inc. | métodos e composições para produção de nucleosídeo trifosfato e ácido ribonucleico |
| WO2019094859A1 (en) | 2017-11-10 | 2019-05-16 | Northwestern University | Cell-free protein synthesis platform derived from cellular extracts of vibrio natriegens |
| US11814621B2 (en) | 2018-06-01 | 2023-11-14 | Northwestern University | Expanding the chemical substrates for genetic code reprogramming |
| WO2020010356A1 (en) | 2018-07-06 | 2020-01-09 | Northwestern University | Ribosome variants for sequence defined polymer synthesis |
| US12098433B2 (en) | 2018-08-03 | 2024-09-24 | Northwestern University | On demand, portable, cell-free molecular sensing platform |
| CN113490748A (zh) | 2019-02-25 | 2021-10-08 | 西北大学 | 来源于梭菌属提取物的无细胞蛋白质合成平台 |
| JP2022535651A (ja) * | 2019-04-12 | 2022-08-10 | ネイチャーズ ツールボックス,インク. | 好熱性タンパク質を利用した組換えインビトロ転写及び翻訳のための系、方法及び組成物 |
| EP4010350A4 (de) | 2019-08-09 | 2023-11-22 | Nutcracker Therapeutics, Inc. | Verfahren und vorrichtungen zur herstellung für die entfernung von material aus einer therapeutischen zusammensetzung |
| WO2024120767A1 (en) * | 2022-12-05 | 2024-06-13 | Novozymes A/S | Modified rna polymerase activities |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU7625298A (en) * | 1996-12-03 | 1998-06-29 | Scriptgen Pharmaceuticals, Inc. | M. tuberculosis RNA polymerase alpha subunit |
| AU4241400A (en) * | 1999-04-16 | 2000-11-02 | Board Of Trustees Of The University Of Arkansas, The | Agrobacterium tumefaciens rpoa gene |
-
2001
- 2001-07-27 EP EP01402049A patent/EP1279736A1/de not_active Withdrawn
-
2002
- 2002-07-26 DE DE60228847T patent/DE60228847D1/de not_active Expired - Lifetime
- 2002-07-26 EP EP02764858A patent/EP1412504B1/de not_active Expired - Lifetime
- 2002-07-26 WO PCT/EP2002/009423 patent/WO2003012114A2/en not_active Ceased
- 2002-07-26 AU AU2002329256A patent/AU2002329256A1/en not_active Abandoned
- 2002-07-26 AT AT02764858T patent/ATE408017T1/de not_active IP Right Cessation
-
2004
- 2004-01-27 US US10/764,581 patent/US7186525B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US7186525B2 (en) | 2007-03-06 |
| AU2002329256A1 (en) | 2003-02-17 |
| WO2003012114A2 (en) | 2003-02-13 |
| DE60228847D1 (de) | 2008-10-23 |
| EP1412504B1 (de) | 2008-09-10 |
| WO2003012114A3 (en) | 2003-08-28 |
| US20050032086A1 (en) | 2005-02-10 |
| EP1279736A1 (de) | 2003-01-29 |
| EP1412504A2 (de) | 2004-04-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |