ATE405254T1 - Transdermal verabreichtes tolterodin als antimuskarin-wirkstoff zur behandlung der hyperaktiven blase - Google Patents
Transdermal verabreichtes tolterodin als antimuskarin-wirkstoff zur behandlung der hyperaktiven blaseInfo
- Publication number
- ATE405254T1 ATE405254T1 AT99946522T AT99946522T ATE405254T1 AT E405254 T1 ATE405254 T1 AT E405254T1 AT 99946522 T AT99946522 T AT 99946522T AT 99946522 T AT99946522 T AT 99946522T AT E405254 T1 ATE405254 T1 AT E405254T1
- Authority
- AT
- Austria
- Prior art keywords
- tolterodine
- antimuscarino
- act
- treatment
- hyperactive bladder
- Prior art date
Links
- 206010020853 Hypertonic bladder Diseases 0.000 title abstract 3
- OOGJQPCLVADCPB-HXUWFJFHSA-N tolterodine Chemical compound C1([C@@H](CCN(C(C)C)C(C)C)C=2C(=CC=C(C)C=2)O)=CC=CC=C1 OOGJQPCLVADCPB-HXUWFJFHSA-N 0.000 title abstract 2
- 229960004045 tolterodine Drugs 0.000 title abstract 2
- BDIAUFOIMFAIPU-UHFFFAOYSA-N valepotriate Natural products CC(C)CC(=O)OC1C=C(C(=COC2OC(=O)CC(C)C)COC(C)=O)C2C11CO1 BDIAUFOIMFAIPU-UHFFFAOYSA-N 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 abstract 4
- 239000000203 mixture Substances 0.000 abstract 4
- 208000009722 Overactive Urinary Bladder Diseases 0.000 abstract 2
- 208000020629 overactive bladder Diseases 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000002207 metabolite Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 230000002685 pulmonary effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9802864A SE9802864D0 (sv) | 1998-08-27 | 1998-08-27 | Transdermally administered tolterodine as antimuscarinic agent for the treatment of overactive bladder |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE405254T1 true ATE405254T1 (de) | 2008-09-15 |
Family
ID=20412370
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99946522T ATE405254T1 (de) | 1998-08-27 | 1999-08-26 | Transdermal verabreichtes tolterodin als antimuskarin-wirkstoff zur behandlung der hyperaktiven blase |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US6517864B1 (https=) |
| EP (1) | EP1105111B1 (https=) |
| JP (1) | JP2002523446A (https=) |
| AT (1) | ATE405254T1 (https=) |
| AU (1) | AU758399B2 (https=) |
| CA (1) | CA2341063C (https=) |
| DE (1) | DE69939382D1 (https=) |
| ES (2) | ES2353765T3 (https=) |
| NZ (1) | NZ509928A (https=) |
| SE (1) | SE9802864D0 (https=) |
| TW (1) | TWI253349B (https=) |
| WO (1) | WO2000012070A1 (https=) |
| ZA (1) | ZA200002488B (https=) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998003067A1 (en) * | 1996-07-19 | 1998-01-29 | Gunnar Aberg | S(-)-tolterodine in the treatment of urinary and gastrointestinal disorders |
| EP0957073A1 (en) * | 1998-05-12 | 1999-11-17 | Schwarz Pharma Ag | Novel derivatives of 3,3-diphenylpropylamines |
| SE9802864D0 (sv) * | 1998-08-27 | 1998-08-27 | Pharmacia & Upjohn Ab | Transdermally administered tolterodine as antimuscarinic agent for the treatment of overactive bladder |
| PT1031346E (pt) | 1999-01-27 | 2002-09-30 | Idea Ag | Vacinacao nao invasiva atraves da pele |
| SI1031347T1 (en) | 1999-01-27 | 2002-10-31 | Idea Ag | Transnasal transport/immunisation with highly adaptable carriers |
| DE19922662C1 (de) | 1999-05-18 | 2000-12-28 | Sanol Arznei Schwarz Gmbh | Transdermales therapeutisches System (TTS) Tolterodin enthaltend |
| WO2001001962A1 (en) * | 1999-07-05 | 2001-01-11 | Idea Ag. | A method for the improvement of transport across adaptable semi-permeable barriers |
| DE19932651A1 (de) * | 1999-07-13 | 2001-01-18 | Hexal Ag | Transdermales therapeutisches System zur Anwendung von Tolterodin |
| JP2005513080A (ja) * | 2001-12-20 | 2005-05-12 | フェムファーマ, インコーポレイテッド | 薬物の膣送達 |
| JP2006515026A (ja) * | 2003-01-02 | 2006-05-18 | フェムファーマ ホールディング カンパニー, インコーポレイテッド | 乳房の疾患および障害の処置のための薬学的調製物 |
| US9173836B2 (en) | 2003-01-02 | 2015-11-03 | FemmeParma Holding Company, Inc. | Pharmaceutical preparations for treatments of diseases and disorders of the breast |
| US20040191345A1 (en) * | 2003-03-26 | 2004-09-30 | Fredrik Nicklasson | New formulations and use thereof |
| DE10315917A1 (de) * | 2003-04-08 | 2004-11-18 | Schwarz Pharma Ag | Hochreine Basen von 3,3-Diphenylpropylaminmonoestern |
| JP5548329B2 (ja) * | 2003-08-04 | 2014-07-16 | 杏林製薬株式会社 | 経皮吸収型製剤 |
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| EA023147B1 (ru) * | 2006-04-13 | 2016-04-29 | Тева Фармасьютикалс Интернешнл Гмбх | Трансдермальный пластырь для лечения мигрени |
| AU2012261753B2 (en) * | 2006-04-13 | 2015-03-05 | Teva Pharmaceuticals International Gmbh | Transdermal methods and systems for the delivery of anti-migraine compounds |
| US7803778B2 (en) | 2006-05-23 | 2010-09-28 | Theracos, Inc. | Glucose transport inhibitors and methods of use |
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| EP2175843B1 (en) | 2007-08-08 | 2014-10-08 | Inventia Healthcare Private Limited | Extended release compositions comprising tolterodine |
| NZ583369A (en) | 2007-08-23 | 2011-08-26 | Theracos Inc | Benzylbenzene derivatives and methods of use |
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| JP2021534196A (ja) | 2018-08-23 | 2021-12-09 | シージェン インコーポレイテッド | 抗tigit抗体 |
| EP4185310A4 (en) * | 2020-07-23 | 2024-09-04 | Kimberly-Clark Worldwide, Inc. | METHOD OF MODULATING THE BLADDER MICROBIOME TO IMPROVE BLADDER HEALTH |
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| EP4320160A1 (en) | 2021-04-09 | 2024-02-14 | Seagen Inc. | Methods of treating cancer with anti-tigit antibodies |
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Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5382600A (en) | 1988-01-22 | 1995-01-17 | Pharmacia Aktiebolag | 3,3-diphenylpropylamines and pharmaceutical compositions thereof |
| ZA933349B (en) * | 1992-05-13 | 1994-06-15 | Alza Corp | Transdermal administration of oxybutynin |
| WO1998003067A1 (en) | 1996-07-19 | 1998-01-29 | Gunnar Aberg | S(-)-tolterodine in the treatment of urinary and gastrointestinal disorders |
| PT877600E (pt) * | 1996-08-09 | 2004-02-27 | Alcon Mfg Ltd | Sistemas conservantes para composicoes farmaceuticas contendo ciclodextrinas |
| SE9802864D0 (sv) * | 1998-08-27 | 1998-08-27 | Pharmacia & Upjohn Ab | Transdermally administered tolterodine as antimuscarinic agent for the treatment of overactive bladder |
-
1998
- 1998-08-27 SE SE9802864A patent/SE9802864D0/xx unknown
-
1999
- 1999-08-26 AT AT99946522T patent/ATE405254T1/de not_active IP Right Cessation
- 1999-08-26 NZ NZ509928A patent/NZ509928A/en unknown
- 1999-08-26 US US09/763,654 patent/US6517864B1/en not_active Expired - Fee Related
- 1999-08-26 DE DE69939382T patent/DE69939382D1/de not_active Expired - Lifetime
- 1999-08-26 CA CA002341063A patent/CA2341063C/en not_active Expired - Fee Related
- 1999-08-26 AU AU58919/99A patent/AU758399B2/en not_active Ceased
- 1999-08-26 ES ES99946521T patent/ES2353765T3/es not_active Expired - Lifetime
- 1999-08-26 EP EP99946522A patent/EP1105111B1/en not_active Expired - Lifetime
- 1999-08-26 WO PCT/SE1999/001464 patent/WO2000012070A1/en not_active Ceased
- 1999-08-26 ES ES99946522T patent/ES2310942T3/es not_active Expired - Lifetime
- 1999-08-26 JP JP2000567189A patent/JP2002523446A/ja active Pending
- 1999-08-27 TW TW088114752A patent/TWI253349B/zh not_active IP Right Cessation
-
2000
- 2000-05-19 ZA ZA200002488A patent/ZA200002488B/xx unknown
-
2002
- 2002-11-22 US US10/301,719 patent/US7008637B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20030124179A1 (en) | 2003-07-03 |
| US7008637B2 (en) | 2006-03-07 |
| CA2341063C (en) | 2008-02-12 |
| AU5891999A (en) | 2000-03-21 |
| ZA200002488B (en) | 2001-05-16 |
| AU758399B2 (en) | 2003-03-20 |
| CA2341063A1 (en) | 2000-03-09 |
| US6517864B1 (en) | 2003-02-11 |
| JP2002523446A (ja) | 2002-07-30 |
| WO2000012070A1 (en) | 2000-03-09 |
| EP1105111B1 (en) | 2008-08-20 |
| TWI253349B (en) | 2006-04-21 |
| DE69939382D1 (de) | 2008-10-02 |
| EP1105111A1 (en) | 2001-06-13 |
| SE9802864D0 (sv) | 1998-08-27 |
| NZ509928A (en) | 2003-08-29 |
| ES2353765T3 (es) | 2011-03-04 |
| ES2310942T3 (es) | 2009-01-16 |
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