ATE395345T1 - Imidazol-4-yl-ethynyl-pyridin-derivate - Google Patents
Imidazol-4-yl-ethynyl-pyridin-derivateInfo
- Publication number
- ATE395345T1 ATE395345T1 AT04717578T AT04717578T ATE395345T1 AT E395345 T1 ATE395345 T1 AT E395345T1 AT 04717578 T AT04717578 T AT 04717578T AT 04717578 T AT04717578 T AT 04717578T AT E395345 T1 ATE395345 T1 AT E395345T1
- Authority
- AT
- Austria
- Prior art keywords
- ethynyl
- imidazole
- pyridine derivatives
- pyridine
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Addiction (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03004952 | 2003-03-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE395345T1 true ATE395345T1 (de) | 2008-05-15 |
Family
ID=32981724
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04717578T ATE395345T1 (de) | 2003-03-10 | 2004-03-05 | Imidazol-4-yl-ethynyl-pyridin-derivate |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US7153874B2 (fr) |
| EP (1) | EP1606277B8 (fr) |
| JP (1) | JP4404896B2 (fr) |
| KR (1) | KR100742019B1 (fr) |
| CN (1) | CN100358889C (fr) |
| AR (1) | AR043501A1 (fr) |
| AT (1) | ATE395345T1 (fr) |
| AU (1) | AU2004220382B2 (fr) |
| BR (1) | BRPI0408093A (fr) |
| CA (1) | CA2516682C (fr) |
| CL (1) | CL2004000449A1 (fr) |
| CO (1) | CO5601027A2 (fr) |
| DE (1) | DE602004013746D1 (fr) |
| DK (1) | DK1606277T3 (fr) |
| ES (1) | ES2305739T3 (fr) |
| HK (1) | HK1089443A1 (fr) |
| HR (1) | HRP20050774A2 (fr) |
| IL (1) | IL170129A (fr) |
| MX (1) | MXPA05009524A (fr) |
| MY (1) | MY135491A (fr) |
| NO (1) | NO20054136L (fr) |
| NZ (1) | NZ541643A (fr) |
| PA (1) | PA8597301A1 (fr) |
| PE (1) | PE20041061A1 (fr) |
| PL (1) | PL1606277T3 (fr) |
| PT (1) | PT1606277E (fr) |
| RU (1) | RU2342383C2 (fr) |
| SI (1) | SI1606277T1 (fr) |
| TW (1) | TWI292318B (fr) |
| WO (1) | WO2004080998A1 (fr) |
| ZA (1) | ZA200506834B (fr) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA80888C2 (en) * | 2003-06-05 | 2007-11-12 | Hoffmann La Roche | Imidazole derivatives as glutmate receptor antagonists |
| US7452909B2 (en) * | 2003-09-04 | 2008-11-18 | Hoffman-La Roche Inc. | Imidazole derivatives |
| EP1756086B1 (fr) * | 2004-06-01 | 2008-06-04 | F.Hoffmann-La Roche Ag | Pyridin-4-yl-ethynyl-imidazoles et pyrazoles, antagonistes du recepteur mglur5 |
| KR101057032B1 (ko) * | 2004-06-01 | 2011-08-16 | 에프. 호프만-라 로슈 아게 | Ｍｇｌｕ5 수용체 길항제로서 피리딘-4-일-에틴일-이미다졸및 피라졸 |
| CA2620333A1 (fr) | 2005-08-26 | 2007-03-01 | Braincells, Inc. | Neurogenese par modulation du recepteur muscarinique |
| EP2258359A3 (fr) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenèse par modulation des récepteurs muscariniques avec sabcomeline |
| AU2006304787A1 (en) | 2005-10-21 | 2007-04-26 | Braincells, Inc. | Modulation of neurogenesis by PDE inhibition |
| WO2007053596A1 (fr) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | Modulation de la neurogenese dont la mediation est assuree par recepteur gaba |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| DE102006011574A1 (de) * | 2006-03-10 | 2007-10-31 | Grünenthal GmbH | Substituierte Imidazo[2,1-b]thiazol-Verbindungen und ihre Verwendung zur Herstellung von Arzneimitteln |
| EP2021000A2 (fr) | 2006-05-09 | 2009-02-11 | Braincells, Inc. | Neurogenèse par modulation de l'angiotensine |
| US7678808B2 (en) | 2006-05-09 | 2010-03-16 | Braincells, Inc. | 5 HT receptor mediated neurogenesis |
| AU2007292848A1 (en) * | 2006-09-08 | 2008-03-13 | Braincells, Inc. | Combinations containing a 4-acylaminopyridine derivative |
| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| RS54853B1 (sr) | 2006-12-21 | 2016-10-31 | Hoffmann La Roche | Polimorfi antagonista mglur5 receptora |
| US20100216805A1 (en) | 2009-02-25 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
| US8334287B2 (en) | 2009-07-17 | 2012-12-18 | Hoffmann-La Roche Inc. | Imidazoles |
| US8586581B2 (en) * | 2009-12-17 | 2013-11-19 | Hoffmann-La Roche Inc | Ethynyl compounds useful for treatment of CNS disorders |
| HUE025031T2 (en) | 2011-04-26 | 2016-02-29 | Hoffmann La Roche | Ethinyl derivatives as positive allosteric modulators of MGLUR5 |
| UA116023C2 (uk) | 2013-07-08 | 2018-01-25 | Ф. Хоффманн-Ля Рош Аг | Етинільні похідні як антагоністи метаботропного глутаматного рецептора |
| US10941132B2 (en) | 2016-01-05 | 2021-03-09 | Hua Medicine (Shanghai) Ltd. | Pyrazole derivatives |
| AR110724A1 (es) | 2017-01-10 | 2019-04-24 | Bayer Cropscience Ag | Derivados heterocíclicos como pesticidas |
| AR113206A1 (es) | 2017-01-10 | 2020-02-19 | Bayer Cropscience Ag | Derivados heterocíclicos como pesticidas |
| EP4069685A1 (fr) * | 2019-12-02 | 2022-10-12 | F. Hoffmann-La Roche AG | Inhibiteurs d'alcynyle- (hétéroaryl)-carboxamide hcn1 |
| CN111416154B (zh) * | 2020-05-22 | 2021-08-06 | 松山湖材料实验室 | 高电压锂离子电池电解液硅基吡啶添加剂、电解液及其电池 |
| BR112023019532A2 (pt) | 2021-03-27 | 2023-10-31 | Syngenta Crop Protection Ag | Derivados de amida isonicotínicos microbicidas |
| WO2023089049A2 (fr) | 2021-11-19 | 2023-05-25 | Syngenta Crop Protection Ag | Dérivés d'amide isonicotinique microbiocide |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3303199A (en) | 1963-07-15 | 1967-02-07 | Geigy Chem Corp | Certain imidazolone derivatives and process for making same |
| US3341548A (en) | 1964-04-29 | 1967-09-12 | Hoffmann La Roche | Nitroimidazoles and their preparation |
| DE2035905A1 (de) | 1970-07-20 | 1972-02-03 | Chemische Fabrik Stockhausen & Cie.,4150Krefeld | Imidazolverbindungen und deren Herstellungsverfahren |
| CA1174673A (fr) | 1981-02-27 | 1984-09-18 | Walter Hunkeler | Imidazodiazepines |
| US4711962A (en) | 1984-10-18 | 1987-12-08 | Stauffer Chemical Company | Process for selective preparation of ratios of isomers formed on N-substitution of asymmetric imidazoles |
| US4882343A (en) * | 1987-08-28 | 1989-11-21 | G. D. Searle & Co. | Biarylalkylimidazole derivatives as anti-depressants |
| HU217958B (hu) | 1989-06-30 | 2000-05-28 | E. I. Du Pont De Nemours And Co. | Helyettesített imidazolszármazékok, ezeket tartalmazó gyógyszerkészítmények és eljárás előállításukra |
| TW544448B (en) | 1997-07-11 | 2003-08-01 | Novartis Ag | Pyridine derivatives |
| BR9811933A (pt) | 1997-08-14 | 2000-09-05 | Hoffmann La Roche | Vinil éteres heterocìclicos contra distúrbios neurológicos |
| EP1214303A1 (fr) | 1999-08-31 | 2002-06-19 | Merck & Co., Inc. | Composes heterocycliques et procedes d'utilisation de ceux-ci |
| EP1349839B8 (fr) | 2000-12-04 | 2005-06-22 | F. Hoffmann-La Roche Ag | Derives phenylethenyle ou phenylethinyle servant d'antagonistes de recepteur de glutamate |
| CA2470612A1 (fr) * | 2001-12-19 | 2003-07-03 | Merck & Co., Inc. | Imidazoles substitues par heteroaryle modulateurs du recepteur metabotropique du glutamate de type 5 |
-
2004
- 2004-03-04 TW TW093105737A patent/TWI292318B/zh not_active IP Right Cessation
- 2004-03-05 JP JP2006504558A patent/JP4404896B2/ja not_active Expired - Fee Related
- 2004-03-05 RU RU2005131165/04A patent/RU2342383C2/ru not_active IP Right Cessation
- 2004-03-05 CA CA002516682A patent/CA2516682C/fr not_active Expired - Fee Related
- 2004-03-05 DE DE602004013746T patent/DE602004013746D1/de not_active Expired - Lifetime
- 2004-03-05 KR KR1020057016753A patent/KR100742019B1/ko not_active IP Right Cessation
- 2004-03-05 DK DK04717578T patent/DK1606277T3/da active
- 2004-03-05 CN CNB2004800065725A patent/CN100358889C/zh not_active Expired - Fee Related
- 2004-03-05 SI SI200430735T patent/SI1606277T1/sl unknown
- 2004-03-05 ES ES04717578T patent/ES2305739T3/es not_active Expired - Lifetime
- 2004-03-05 EP EP04717578A patent/EP1606277B8/fr not_active Expired - Lifetime
- 2004-03-05 WO PCT/EP2004/002276 patent/WO2004080998A1/fr active IP Right Grant
- 2004-03-05 NZ NZ541643A patent/NZ541643A/en unknown
- 2004-03-05 AU AU2004220382A patent/AU2004220382B2/en not_active Ceased
- 2004-03-05 AT AT04717578T patent/ATE395345T1/de active
- 2004-03-05 MX MXPA05009524A patent/MXPA05009524A/es active IP Right Grant
- 2004-03-05 PL PL04717578T patent/PL1606277T3/pl unknown
- 2004-03-05 PT PT04717578T patent/PT1606277E/pt unknown
- 2004-03-05 BR BRPI0408093-9A patent/BRPI0408093A/pt not_active IP Right Cessation
- 2004-03-05 PA PA20048597301A patent/PA8597301A1/es unknown
- 2004-03-08 US US10/795,619 patent/US7153874B2/en not_active Expired - Fee Related
- 2004-03-08 PE PE2004000252A patent/PE20041061A1/es not_active Application Discontinuation
- 2004-03-08 CL CL200400449A patent/CL2004000449A1/es unknown
- 2004-03-08 AR ARP040100722A patent/AR043501A1/es not_active Application Discontinuation
- 2004-03-09 MY MYPI20040806A patent/MY135491A/en unknown
-
2005
- 2005-08-04 IL IL170129A patent/IL170129A/en not_active IP Right Cessation
- 2005-08-25 ZA ZA200506834A patent/ZA200506834B/en unknown
- 2005-08-25 CO CO05085015A patent/CO5601027A2/es active IP Right Grant
- 2005-09-05 HR HR20050774A patent/HRP20050774A2/xx not_active Application Discontinuation
- 2005-09-06 NO NO20054136A patent/NO20054136L/no not_active Application Discontinuation
-
2006
- 2006-09-06 HK HK06109889A patent/HK1089443A1/xx not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
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| UEP | Publication of translation of european patent specification |
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