ATE394509T1 - Molekulare stäbchen enthaltende oligonukleotide - Google Patents

Molekulare stäbchen enthaltende oligonukleotide

Info

Publication number
ATE394509T1
ATE394509T1 AT04028280T AT04028280T ATE394509T1 AT E394509 T1 ATE394509 T1 AT E394509T1 AT 04028280 T AT04028280 T AT 04028280T AT 04028280 T AT04028280 T AT 04028280T AT E394509 T1 ATE394509 T1 AT E394509T1
Authority
AT
Austria
Prior art keywords
oligonucleotides containing
containing molecular
molecular rods
nucleotide residue
oligonucleotides
Prior art date
Application number
AT04028280T
Other languages
English (en)
Inventor
Dieter Heindl
Astrid Reiser
Karim Tabiti
Martina Junius
Alexander Hauber
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE394509T1 publication Critical patent/ATE394509T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808—Automated or kit

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
AT04028280T 2003-12-02 2004-11-30 Molekulare stäbchen enthaltende oligonukleotide ATE394509T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03027753 2003-12-02

Publications (1)

Publication Number Publication Date
ATE394509T1 true ATE394509T1 (de) 2008-05-15

Family

ID=34610060

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04028280T ATE394509T1 (de) 2003-12-02 2004-11-30 Molekulare stäbchen enthaltende oligonukleotide

Country Status (7)

Country Link
US (1) US7541448B2 (de)
EP (1) EP1538221B1 (de)
JP (1) JP2005200405A (de)
AT (1) ATE394509T1 (de)
CA (1) CA2494571C (de)
DE (1) DE602004013520D1 (de)
ES (1) ES2305652T3 (de)

Families Citing this family (15)

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Publication number Priority date Publication date Assignee Title
JP5493117B2 (ja) * 2006-02-15 2014-05-14 国立大学法人岐阜大学 オリゴヌクレオチド誘導体及びその利用
US20090181391A1 (en) * 2007-11-01 2009-07-16 Zymo Research Corporation Methods for analysis of dna methylation percentage
CN102449167B (zh) 2009-05-26 2014-12-17 厦门大学 一种检测核酸序列变异的方法
CA2781519A1 (en) 2009-09-16 2011-03-24 Genentech, Inc. Coiled coil and/or tether containing protein complexes and uses thereof
TW201138821A (en) 2010-03-26 2011-11-16 Roche Glycart Ag Bispecific antibodies
US9506057B2 (en) 2010-03-26 2016-11-29 Integrated Dna Technologies, Inc. Modifications for antisense compounds
WO2011120049A1 (en) * 2010-03-26 2011-09-29 Integrated Dna Technologies, Inc. Methods for enhancing nucleic acid hybridization
EP2896696B1 (de) 2010-09-07 2017-12-27 Integrated Dna Technologies, Inc. Modifikationen für Antisense-Verbindungen
CN103384825B (zh) 2010-12-23 2017-05-24 霍夫曼-拉罗奇有限公司 通过二价结合剂检测经翻译后修饰的多肽
WO2012085113A1 (en) 2010-12-23 2012-06-28 Roche Diagnostics Gmbh Binding agent
JP5766296B2 (ja) 2010-12-23 2015-08-19 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ ポリペプチド−ポリヌクレオチド複合体、およびエフェクター成分の標的化された送達におけるその使用
KR20140127854A (ko) 2012-02-10 2014-11-04 제넨테크, 인크. 단일-쇄 항체 및 다른 이종다량체
RU2639287C2 (ru) 2012-06-27 2017-12-20 Ф. Хоффманн-Ля Рош Аг Способ отбора и получения высокоселективных и мультиспецифичных нацеливающих групп с заданными свойствами, включающих по меньшей мере две различные связывающие группировки, и их применения
WO2014001325A1 (en) 2012-06-27 2014-01-03 F. Hoffmann-La Roche Ag Method for making antibody fc-region conjugates comprising at least one binding entity that specifically binds to a target and uses thereof
WO2016087416A1 (en) 2014-12-03 2016-06-09 F. Hoffmann-La Roche Ag Multispecific antibodies

Family Cites Families (19)

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Publication number Priority date Publication date Assignee Title
US5118801A (en) 1988-09-30 1992-06-02 The Public Health Research Institute Nucleic acid process containing improved molecular switch
US5141837A (en) 1990-02-23 1992-08-25 Eastman Kodak Company Method for preparing coating compositions containing photoconductive perylene pigments
US5210015A (en) 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
US5290925A (en) 1990-12-20 1994-03-01 Abbott Laboratories Methods, kits, and reactive supports for 3' labeling of oligonucleotides
US5538848A (en) 1994-11-16 1996-07-23 Applied Biosystems Division, Perkin-Elmer Corp. Method for detecting nucleic acid amplification using self-quenching fluorescence probe
JP3482209B2 (ja) * 1994-03-18 2003-12-22 ジェロン・コーポレーション オリゴヌクレオチドｎ３’→ｐ５’ホスホルアミデート：合成および化合物；ハイブリダイゼーションおよびヌクレアーゼ耐性特性
US5700923A (en) * 1994-09-29 1997-12-23 Hybridon, Inc. Finderons and methods of their preparation and use
JPH08319295A (ja) * 1995-03-22 1996-12-03 Toagosei Co Ltd 核酸化合物及びその合成方法
US5770715A (en) * 1995-03-22 1998-06-23 Toagosei Co., Ltd. Hammerhead-like nucleic acid analogues and their synthesis
US6017700A (en) * 1995-08-04 2000-01-25 Bayer Corporation Cationic oligonucleotides, and related methods of synthesis and use
CA2257109C (en) 1996-06-04 2009-10-06 University Of Utah Research Foundation Monitoring hybridization during pcr
JP4281877B2 (ja) 1996-06-04 2009-06-17 ユニバーシティ オブ ユタ リサーチ ファウンデーション 生物学的プロセスを実行し且つモニタリングするためのシステムと方法
JP2002514909A (ja) * 1996-09-24 2002-05-21 ラピジーン，インコーポレイテッド ハイブリダイゼーション特異性を増強するための組成物および方法
US5932711A (en) * 1997-03-05 1999-08-03 Mosaic Technologies, Inc. Nucleic acid-containing polymerizable complex
ATE340870T1 (de) * 1998-04-03 2006-10-15 Compound Therapeutics Inc Adressierbare protein arrays
EP1276702A2 (de) 2000-03-31 2003-01-22 Genentech, Inc. Zusammensetzungen und verfahren zur detektion und quantifizierung von genexpression
US7671036B2 (en) * 2000-06-23 2010-03-02 Yissum Research Development Company Of The Hebrew University Of Jerusalem Positively-charged peptide nucleic acid analogs with improved properties
US6942972B2 (en) 2001-10-24 2005-09-13 Beckman Coulter, Inc. Efficient synthesis of protein-oligonucleotide conjugates
GB0130868D0 (en) * 2001-12-24 2002-02-06 Univ Strathclyde New compounds

Also Published As

Publication number Publication date
EP1538221B1 (de) 2008-05-07
EP1538221A1 (de) 2005-06-08
ES2305652T3 (es) 2008-11-01
JP2005200405A (ja) 2005-07-28
DE602004013520D1 (de) 2008-06-19
CA2494571A1 (en) 2005-06-02
CA2494571C (en) 2010-02-09
US7541448B2 (en) 2009-06-02
US20050142598A1 (en) 2005-06-30

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