ATE541944T1 - Polynukleotidprimer - Google Patents

Polynukleotidprimer

Info

Publication number
ATE541944T1
ATE541944T1 AT06726631T AT06726631T ATE541944T1 AT E541944 T1 ATE541944 T1 AT E541944T1 AT 06726631 T AT06726631 T AT 06726631T AT 06726631 T AT06726631 T AT 06726631T AT E541944 T1 ATE541944 T1 AT E541944T1
Authority
AT
Austria
Prior art keywords
polynucleotide primer
primer
polynucleotide
sequence
nucleotides
Prior art date
Application number
AT06726631T
Other languages
English (en)
Inventor
Nicola Jo Thelwell
Paul Francis Ravetto
David Mark Whitcombe
Original Assignee
Qiagen Manchester Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34586669&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE541944(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Qiagen Manchester Ltd filed Critical Qiagen Manchester Ltd
Application granted granted Critical
Publication of ATE541944T1 publication Critical patent/ATE541944T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6851—Quantitative amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT06726631T 2005-04-04 2006-04-04 Polynukleotidprimer ATE541944T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0506807A GB2424886A (en) 2005-04-04 2005-04-04 Polynucleotide primers against epidermal growth factor receptor and method of detecting gene mutations
PCT/GB2006/001227 WO2006106316A2 (en) 2005-04-04 2006-04-04 Polynucleotide primers

Publications (1)

Publication Number Publication Date
ATE541944T1 true ATE541944T1 (de) 2012-02-15

Family

ID=34586669

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06726631T ATE541944T1 (de) 2005-04-04 2006-04-04 Polynukleotidprimer

Country Status (6)

Country Link
US (3) US9029084B2 (de)
EP (2) EP1866438B2 (de)
JP (1) JP5761891B2 (de)
AT (1) ATE541944T1 (de)
GB (1) GB2424886A (de)
WO (1) WO2006106316A2 (de)

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NZ566387A (en) * 2005-10-05 2010-05-28 Astrazeneca Uk Ltd Method to predict or monitor the response of a patient to an ErbB receptor drug by screening for mutations in an ErbB receptor
US8999634B2 (en) 2007-04-27 2015-04-07 Quest Diagnostics Investments Incorporated Nucleic acid detection combining amplification with fragmentation
GB2453173A (en) * 2007-09-28 2009-04-01 Dxs Ltd Polynucleotide primers
JP2010279264A (ja) * 2009-06-03 2010-12-16 Tottori Univ Ｅｇｆｒ遺伝子変異検出プライマーセット、それを含むｅｇｆｒ遺伝子変異検出キット、およびそれを用いてｅｇｆｒ遺伝子変異検出を行うための核酸増幅装置
CN102234683B (zh) * 2010-04-23 2013-07-17 广州益善生物技术有限公司 一种egfr基因突变检测液相芯片
JP5859274B2 (ja) * 2010-10-29 2016-02-10 アークレイ株式会社 Ｅｇｆｒ遺伝子の多型検出用プローブ、増幅用プライマーおよびその用途
JP5860667B2 (ja) * 2010-10-29 2016-02-16 アークレイ株式会社 Ｅｇｆｒエクソン２１ｌ８５８ｒ遺伝子多型検出用プライマーセット及びその用途
US20120164641A1 (en) * 2010-12-22 2012-06-28 Roche Molecular Systems, Inc. Methods and Compositions for Detecting Mutation in the Human Epidermal Growth Factor Receptor Gene
WO2012157684A1 (ja) * 2011-05-16 2012-11-22 地方独立行政法人 大阪府立病院機構 血中ｄｎａの定量的検出による悪性新生物の病勢の進行を評価する方法
CN103184274A (zh) * 2011-12-27 2013-07-03 上海复星医学科技发展有限公司 一种ldr技术的egfr突变检测试剂盒
CN102747157B (zh) * 2012-07-16 2014-01-22 武汉海吉力生物科技有限公司 用于检测人类egfr基因突变的引物、探针、试剂盒及检测方法
US20140341884A1 (en) * 2012-12-04 2014-11-20 Roche Molecular Systems, Inc. Novel Complex Mutations in the Epidermal Growth Factor Receptor Kinase Domain
CN106795567B (zh) 2014-10-09 2021-07-30 豪夫迈·罗氏有限公司 在表皮生长因子受体激酶结构域中的突变

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US5830713A (en) * 1986-11-04 1998-11-03 Protein Polymer Technologies, Inc. Methods for preparing synthetic repetitive DNA
FR2628027B1 (fr) 1988-03-03 1990-07-20 Hutchinson Procede de fabrication de pieces de carrosserie d'automobile, notamment d'aileron ou becquet arriere, et pieces obtenues par mise en oeuvre de ce procede
IE61148B1 (en) 1988-03-10 1994-10-05 Ici Plc Method of detecting nucleotide sequences
US5993813A (en) * 1988-10-19 1999-11-30 The Dow Chemical Company Family of high affinity, modified antibodies for cancer treatment
AU639726B2 (en) * 1989-09-08 1993-08-05 Duke University Structural alterations of the egf receptor gene in human gliomas
US5210015A (en) 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
US6582908B2 (en) * 1990-12-06 2003-06-24 Affymetrix, Inc. Oligonucleotides
US5474796A (en) * 1991-09-04 1995-12-12 Protogene Laboratories, Inc. Method and apparatus for conducting an array of chemical reactions on a support surface
AU5098393A (en) * 1992-08-14 1994-03-15 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Recombinant toxin with increased half-life
ATE208633T1 (de) * 1994-09-16 2001-11-15 Merck Patent Gmbh Immunokonjugate
US5725493A (en) * 1994-12-12 1998-03-10 Avery; Robert Logan Intravitreal medicine delivery
US6057156A (en) * 1997-01-31 2000-05-02 Robozyme Pharmaceuticals, Inc. Enzymatic nucleic acid treatment of diseases or conditions related to levels of epidermal growth factor receptors
US20030032090A1 (en) * 1997-05-07 2003-02-13 Schering Corporation, A New Jersey Corporation Human receptor proteins; related reagents and methods
US6617438B1 (en) * 1997-11-05 2003-09-09 Sirna Therapeutics, Inc. Oligoribonucleotides with enzymatic activity
US6528640B1 (en) * 1997-11-05 2003-03-04 Ribozyme Pharmaceuticals, Incorporated Synthetic ribonucleic acids with RNAse activity
DE19813317A1 (de) * 1998-03-26 1999-09-30 Roche Diagnostics Gmbh Verbessertes Verfahren zur Primer Extension Präamplifikations-PCR
GB9812768D0 (en) 1998-06-13 1998-08-12 Zeneca Ltd Methods
US6037130A (en) * 1998-07-28 2000-03-14 The Public Health Institute Of The City Of New York, Inc. Wavelength-shifting probes and primers and their use in assays and kits
US7294482B2 (en) * 1998-11-19 2007-11-13 Millennium Pharmaceuticals, Inc. EGF-like nucleic acids
EP1165758A2 (de) 1999-04-12 2002-01-02 Ribozyme Pharmaceuticals, Inc. Regelung der expression von transkiptional-repressorgenen mittels nukleinsäuremolekulen
AU2001245489A1 (en) * 2000-03-07 2001-09-17 Whitehead Institute For Biomedical Research Human single nucleotide polymorphisms
US6365355B1 (en) * 2000-03-28 2002-04-02 The Regents Of The University Of California Chimeric proteins for detection and quantitation of DNA mutations, DNA sequence variations, DNA damage and DNA mismatches
AUPQ909100A0 (en) * 2000-07-28 2000-08-24 Ludwig Institute For Cancer Research A method for diagnosis and treatment
US6444465B1 (en) * 2000-09-29 2002-09-03 Isis Pharmaceuticals, Inc. Antinsense modulation of Her-1 expression
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PT1346041E (pt) * 2000-11-27 2007-06-05 Praecis Pharm Inc Agentes terapêuticos e métodos para a sua utilização no tratamento de uma doença amiloidogénica.
EP1395605B8 (de) * 2001-03-09 2014-12-17 Iterative Therapeutics, Inc. Polymere immunoglobulin-fusionsproteine, die auf fc-gamma-rezeptoren mit geringer affinität zielen
WO2003070912A2 (en) * 2001-06-06 2003-08-28 Sirna Therapeutics, Inc. RNA INTERFERENCE MEDIATED INHIBITION OF EPIDERMAL GROWTH FACTOR RECEPTOR GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
ES2269614T3 (es) * 2001-08-31 2007-04-01 The University Of Utah Research Foundation Cuantificacion de genes en tiempo real con estandares internos.
EP1472375B1 (de) * 2002-01-08 2009-04-01 Novartis Vaccines and Diagnostics, Inc. In kanzerösen mammazellen differentiell exprimierte genprodukte und ihre verwendungsverfahren
AU2003257110A1 (en) * 2002-07-31 2004-02-16 University Of Southern California Polymorphisms for predicting disease and treatment outcome
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AU2003283966A1 (en) 2002-09-25 2004-04-23 Pharmacia Corporation Antisense modulation of farnesoid x receptor expression
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US7910295B2 (en) * 2002-11-14 2011-03-22 John Wayne Cancer Institute Detection of micro metastasis of melanoma and breast cancer in paraffin-embedded tumor draining lymph nodes by multimarker quantitative RT-PCR
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ES2553264T3 (es) * 2004-05-27 2015-12-07 The Regents Of The University Of Colorado Métodos para la predicción del resultado clínico para inhibidores del receptor del factor de crecimiento epidérmico para pacientes de cáncer
ES2564127T5 (es) * 2004-06-04 2020-03-26 Genentech Inc Mutaciones en EGFR

Also Published As

Publication number Publication date
JP2008534025A (ja) 2008-08-28
US20080261219A1 (en) 2008-10-23
GB0506807D0 (en) 2005-05-11
EP1866438B1 (de) 2012-01-18
US20150211076A1 (en) 2015-07-30
EP1866438A2 (de) 2007-12-19
EP1866438B2 (de) 2015-12-23
WO2006106316A2 (en) 2006-10-12
JP5761891B2 (ja) 2015-08-12
US9029084B2 (en) 2015-05-12
EP2314717A1 (de) 2011-04-27
US20130323736A1 (en) 2013-12-05
EP2314717B1 (de) 2016-08-31
WO2006106316A3 (en) 2007-02-15
GB2424886A (en) 2006-10-11

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