ATE372376T1 - Kulturmedium mit sojabohnenextrakt als aminosäuren-quelle und ohne proteinkomplexe tierischen ursprungs - Google Patents

Kulturmedium mit sojabohnenextrakt als aminosäuren-quelle und ohne proteinkomplexe tierischen ursprungs

Info

Publication number
ATE372376T1
ATE372376T1 AT98923023T AT98923023T ATE372376T1 AT E372376 T1 ATE372376 T1 AT E372376T1 AT 98923023 T AT98923023 T AT 98923023T AT 98923023 T AT98923023 T AT 98923023T AT E372376 T1 ATE372376 T1 AT E372376T1
Authority
AT
Austria
Prior art keywords
source
amino acids
culture medium
animal origin
protein complexes
Prior art date
Application number
AT98923023T
Other languages
English (en)
Inventor
Roberto Olivieri
Fabio Sabbatini
Maria Kontakou
Lucia Tagliaferri
Antonella Giglioli
Rino Rappuoli
Original Assignee
Novartis Vaccines & Diagnostic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9710981.3A external-priority patent/GB9710981D0/en
Priority claimed from GBGB9806802.6A external-priority patent/GB9806802D0/en
Application filed by Novartis Vaccines & Diagnostic filed Critical Novartis Vaccines & Diagnostic
Application granted granted Critical
Publication of ATE372376T1 publication Critical patent/ATE372376T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/21Haemophilus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT98923023T 1997-05-28 1998-05-28 Kulturmedium mit sojabohnenextrakt als aminosäuren-quelle und ohne proteinkomplexe tierischen ursprungs ATE372376T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9710981.3A GB9710981D0 (en) 1997-05-28 1997-05-28 Culture medium
GBGB9806802.6A GB9806802D0 (en) 1998-03-30 1998-03-30 Culture medium

Publications (1)

Publication Number Publication Date
ATE372376T1 true ATE372376T1 (de) 2007-09-15

Family

ID=26311607

Family Applications (2)

Application Number Title Priority Date Filing Date
AT07075660T ATE488574T1 (de) 1997-05-28 1998-05-28 Verfahren zur herstellung eines immunogenen faktors von corynebacterium diphtheriae unter verwendung eines kulturmediums mit hefeextrakt als aminosäurenquelle und ohne proteinkomplexe tierischer herkunft
AT98923023T ATE372376T1 (de) 1997-05-28 1998-05-28 Kulturmedium mit sojabohnenextrakt als aminosäuren-quelle und ohne proteinkomplexe tierischen ursprungs

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT07075660T ATE488574T1 (de) 1997-05-28 1998-05-28 Verfahren zur herstellung eines immunogenen faktors von corynebacterium diphtheriae unter verwendung eines kulturmediums mit hefeextrakt als aminosäurenquelle und ohne proteinkomplexe tierischer herkunft

Country Status (10)

Country Link
EP (4) EP1849860B1 (de)
JP (3) JP4173560B2 (de)
AT (2) ATE488574T1 (de)
AU (1) AU7545298A (de)
CY (2) CY1107812T1 (de)
DE (2) DE69842010D1 (de)
DK (1) DK0983342T3 (de)
ES (1) ES2293681T3 (de)
PT (2) PT1849860E (de)
WO (1) WO1998054296A1 (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6475725B1 (en) 1997-06-20 2002-11-05 Baxter Aktiengesellschaft Recombinant cell clones having increased stability and methods of making and using the same
AT409379B (de) 1999-06-02 2002-07-25 Baxter Ag Medium zur protein- und serumfreien kultivierung von zellen
US6558926B1 (en) * 1999-07-16 2003-05-06 Massachusetts Institute Of Technology Method for production of tetanus toxin using media substantially free of animal products
EP1074612A1 (de) * 1999-08-04 2001-02-07 Pasteur Merieux Serums Et Vaccins Verwendung von Pflanzenpeptonen zur Herstellung von DNS Impfstoffe
EA006947B1 (ru) 2001-01-23 2006-06-30 Авентис Пастер Поливалентная менингококковая полисахаридно-белковая конъюгированная вакцина
GB0115176D0 (en) 2001-06-20 2001-08-15 Chiron Spa Capular polysaccharide solubilisation and combination vaccines
AU2003299501A1 (en) * 2002-05-16 2004-05-04 Aventis Pasteur, Inc. Animal component free meningococcal polysaccharide fermentation and seedbank development
JP2005532057A (ja) 2002-07-09 2005-10-27 バクスター・インターナショナル・インコーポレイテッド 細胞を培養するための動物性タンパク質非含有培地
US20040037869A1 (en) * 2002-08-16 2004-02-26 Douglas Cleverly Non-animal product containing veterinary formulations
US7148041B2 (en) 2003-09-25 2006-12-12 Allergan, Inc. Animal product free media and processes for obtaining a botulinum toxin
US7160699B2 (en) 2003-09-25 2007-01-09 Allergan, Inc. Media for clostridium bacterium and processes for obtaining a clostridial toxin
US7452697B2 (en) 2003-09-25 2008-11-18 Allergan, Inc. Chromatographic method and system for purifying a botulinum toxin
US7354740B2 (en) 2003-09-25 2008-04-08 Allergan, Inc. Animal product free system and process for purifying a botulinum toxin
WO2005054443A1 (en) * 2003-12-03 2005-06-16 Aventis Pasteur Limited Cryo-protective agents for microorganisms
US20110097359A1 (en) * 2003-12-12 2011-04-28 Tim Lee Production of diphtheria toxin
GB0408978D0 (en) * 2004-04-22 2004-05-26 Chiron Srl Meningococcal fermentation for preparing conjugate vaccines
WO2006042542A2 (en) * 2004-10-19 2006-04-27 Statens Serum Institut Production of tetanus, diphtheria, and pertussis toxins and toxoids using fermentation media containing no components of animal or soy origin
US20060094104A1 (en) 2004-10-29 2006-05-04 Leopold Grillberger Animal protein-free media for cultivation of cells
NL1029059C2 (nl) * 2005-05-17 2006-11-20 Noord Nl Oliemolen Holding B V Peptidenpreparaat voor het groeien en/of kweken van micro-organismen en/of cellen.
SI1869161T1 (sl) * 2005-10-11 2010-05-31 Probiotical Spa Postopek za pripravo nealergijskih probiotičnih bakterijskih kultur in ustrezna uporaba
EP2522717B1 (de) 2006-01-04 2014-04-02 Baxter International Inc Oligopeptid-freie Zellkulturmedien
EP1893033B1 (de) * 2006-07-07 2008-10-22 Alpro NV Verfahren zur herstellung eines milchprodukt-analogs
DK2114421T3 (en) 2007-03-05 2018-04-23 Om Pharma BACTERIA EXTRACTS FOR RESPIRATORY DISORDERS AND PROCEDURES FOR PREPARING THEREOF
FR2918671B1 (fr) 2007-07-10 2010-10-15 Sanofi Pasteur Milieu de culture d'haemophilus influenzae type b.
US8129139B2 (en) 2009-07-13 2012-03-06 Allergan, Inc. Process for obtaining botulinum neurotoxin
EP2275527A1 (de) * 2009-07-17 2011-01-19 ActoGeniX NV Kulturmedium zur Fermentation von Bakterien welches frei von tierischen Bestandteilen ist
GB2495341B (en) 2011-11-11 2013-09-18 Novartis Ag Fermentation methods and their products
DE102011122891B4 (de) 2011-11-11 2014-12-24 Novartis Ag Fermentationsmedium, das frei von tierischen Bestandteilen ist, zur Herstellung von Diphtherie-Toxoiden zur Verwendung bei der Impfung von Menschen
DE102011118371B4 (de) 2011-11-11 2014-02-13 Novartis Ag Zur Impfung von Menschen geeignete Zusammensetzung, die ein Diphtherie-Toxoid umfasst, sowie Verfahren zu deren Herstellung
EP2592137A1 (de) 2011-11-11 2013-05-15 Novartis AG Fermentierungsmedium ohne Bestandteile tierischen Ursprungs zur Herstellung von Diphtherie-Impfstoffen zur menschlichen Impfung
BR102012013110A2 (pt) 2012-05-31 2014-05-27 Cristalia Prod Quimicos Farm Meio de cultura para bactérias do gênero clostridium livre de componentes de origem animal e processo para produção de sobrenadante contendo uma ou mais proteases com atividade colagenolítica e gelatinolítica
CN104263678A (zh) * 2014-09-02 2015-01-07 成都欧林生物科技股份有限公司 一种白喉杆菌培养基及应用其制备白喉类毒素的方法
EP3783010A1 (de) 2015-05-06 2021-02-24 Wageningen Universiteit Verfahren zur kultivierung von akkermansia
CA3138763A1 (en) 2015-11-17 2017-05-26 Pfizer, Inc. Media and fermentation methods for producing polysaccharides in bacterial cell culture
HUE059629T2 (hu) 2017-04-22 2022-12-28 Biological E Ltd Javított eljárás CRM nagy mennyiségben történõ elõállítására
BR112021013241A2 (pt) * 2019-01-04 2021-09-14 Boehringer Ingelheim Animal Health USA Inc. Cepas atenuadas de bordetella bronchiseptica, vacinas orais contendo as cepas atenuadas e métodos de preparação e uso das mesmas
CN112646747B (zh) * 2021-01-08 2024-03-15 苏州聚微生物科技有限公司 破伤风梭状芽孢杆菌培养基

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4695624A (en) * 1984-05-10 1987-09-22 Merck & Co., Inc. Covalently-modified polyanionic bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins with bigeneric spacers, and methods of preparing such polysaccharides and conjugates and of confirming covalency
GB8924438D0 (en) * 1989-10-31 1989-12-20 Hoffmann La Roche Vaccine composition
DD294502A5 (de) 1990-05-15 1991-10-02 Dessau Tornau Impfstoffwerk Verfahren zur herstellung eines sojahydrolysats fuer mikrobiologische zwecke
IT1251751B (it) * 1991-10-31 1995-05-23 Sclavo Ricerca S R L Metodo per la coltura di microrganismi dei generi helicobacter, campylobacter e arcobacter, utilizzando terreni di coltura contenenti ciclodestrine o metil-cellulosa o loro miscele
DE4220889A1 (de) * 1992-06-25 1994-02-24 Mueller Karl & Co Kg Reaktivierungsmischung für Starterkulturen zur Rohwurstherstellung
US5314822A (en) * 1992-10-15 1994-05-24 Merck & Co., Inc. Method of clonal growth of Streptococcus pneumoniae
EP0624376B1 (de) * 1993-05-13 2000-03-15 American Cyanamid Company Herstellung und Verwendungen von LOS-verminderten Aussenmembran-Proteinen von Gram-negativen Kokken
US5494808A (en) * 1994-09-15 1996-02-27 Merck & Co., Inc. Defined medium OMPC fermentation process
GB9422096D0 (en) * 1994-11-02 1994-12-21 Biocine Spa Combined meningitis vaccine
GB9422331D0 (en) * 1994-11-04 1994-12-21 Biocine Spa H. pylori fermentation process

Also Published As

Publication number Publication date
DE69838383T2 (de) 2008-06-05
ES2293681T3 (es) 2008-03-16
JP4173560B2 (ja) 2008-10-29
JP2002501387A (ja) 2002-01-15
EP2267113A1 (de) 2010-12-29
JP2012005495A (ja) 2012-01-12
EP0983342B1 (de) 2007-09-05
EP1849860A2 (de) 2007-10-31
PT1849860E (pt) 2011-02-23
EP2199382A2 (de) 2010-06-23
EP1849860A3 (de) 2008-04-02
EP0983342A1 (de) 2000-03-08
WO1998054296A1 (en) 1998-12-03
ATE488574T1 (de) 2010-12-15
CY1107812T1 (el) 2013-06-19
JP2008200047A (ja) 2008-09-04
CY1111178T1 (el) 2015-06-11
EP2267113B1 (de) 2013-07-17
EP1849860B1 (de) 2010-11-17
DE69838383D1 (de) 2007-10-18
AU7545298A (en) 1998-12-30
PT983342E (pt) 2007-12-13
EP2199382A3 (de) 2010-09-22
DE69842010D1 (de) 2010-12-30
DK0983342T3 (da) 2008-01-07

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