ATE369380T1 - Impfstoff zur verhütung und behanldung von alzheimer-demenz und von amyloid-bezogenen krankheiten - Google Patents
Impfstoff zur verhütung und behanldung von alzheimer-demenz und von amyloid-bezogenen krankheitenInfo
- Publication number
- ATE369380T1 ATE369380T1 AT02729715T AT02729715T ATE369380T1 AT E369380 T1 ATE369380 T1 AT E369380T1 AT 02729715 T AT02729715 T AT 02729715T AT 02729715 T AT02729715 T AT 02729715T AT E369380 T1 ATE369380 T1 AT E369380T1
- Authority
- AT
- Austria
- Prior art keywords
- vaccine
- related diseases
- amyloid
- dementia
- preventing
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 3
- 229960005486 vaccine Drugs 0.000 title abstract 3
- 208000024827 Alzheimer disease Diseases 0.000 title 1
- 230000002265 prevention Effects 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0007—Nervous system antigens; Prions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/867,847 US20020094335A1 (en) | 1999-11-29 | 2001-05-29 | Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE369380T1 true ATE369380T1 (de) | 2007-08-15 |
Family
ID=25350577
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02729715T ATE369380T1 (de) | 2001-05-29 | 2002-05-29 | Impfstoff zur verhütung und behanldung von alzheimer-demenz und von amyloid-bezogenen krankheiten |
Country Status (9)
Country | Link |
---|---|
US (2) | US20020094335A1 (de) |
EP (1) | EP1392728B1 (de) |
JP (1) | JP2005508863A (de) |
CN (1) | CN1662554A (de) |
AT (1) | ATE369380T1 (de) |
AU (1) | AU2002302255A1 (de) |
CA (1) | CA2449056A1 (de) |
DE (1) | DE60221665D1 (de) |
WO (1) | WO2002096937A2 (de) |
Families Citing this family (86)
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US6905686B1 (en) | 1997-12-02 | 2005-06-14 | Neuralab Limited | Active immunization for treatment of alzheimer's disease |
US6787523B1 (en) | 1997-12-02 | 2004-09-07 | Neuralab Limited | Prevention and treatment of amyloidogenic disease |
US7790856B2 (en) | 1998-04-07 | 2010-09-07 | Janssen Alzheimer Immunotherapy | Humanized antibodies that recognize beta amyloid peptide |
TWI239847B (en) * | 1997-12-02 | 2005-09-21 | Elan Pharm Inc | N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease |
US6750324B1 (en) | 1997-12-02 | 2004-06-15 | Neuralab Limited | Humanized and chimeric N-terminal amyloid beta-antibodies |
US20080050367A1 (en) | 1998-04-07 | 2008-02-28 | Guriq Basi | Humanized antibodies that recognize beta amyloid peptide |
US6761888B1 (en) * | 2000-05-26 | 2004-07-13 | Neuralab Limited | Passive immunization treatment of Alzheimer's disease |
US7964192B1 (en) * | 1997-12-02 | 2011-06-21 | Janssen Alzheimer Immunotherapy | Prevention and treatment of amyloidgenic disease |
US6913745B1 (en) * | 1997-12-02 | 2005-07-05 | Neuralab Limited | Passive immunization of Alzheimer's disease |
US7179892B2 (en) * | 2000-12-06 | 2007-02-20 | Neuralab Limited | Humanized antibodies that recognize beta amyloid peptide |
US20030147882A1 (en) * | 1998-05-21 | 2003-08-07 | Alan Solomon | Methods for amyloid removal using anti-amyloid antibodies |
US6787637B1 (en) | 1999-05-28 | 2004-09-07 | Neuralab Limited | N-Terminal amyloid-β antibodies |
PE20020574A1 (es) * | 2000-12-06 | 2002-07-02 | Wyeth Corp | Anticuerpos humanizados que reconocen el peptido amiloideo beta |
US7700751B2 (en) | 2000-12-06 | 2010-04-20 | Janssen Alzheimer Immunotherapy | Humanized antibodies that recognize β-amyloid peptide |
AU2002327514A1 (en) * | 2001-08-23 | 2003-03-10 | Stanley Stein | Application of peptide conjugates to alzheimer's disease |
AR038568A1 (es) | 2002-02-20 | 2005-01-19 | Hoffmann La Roche | Anticuerpos anti-a beta y su uso |
MY139983A (en) | 2002-03-12 | 2009-11-30 | Janssen Alzheimer Immunotherap | Humanized antibodies that recognize beta amyloid peptide |
WO2004013172A2 (en) * | 2002-07-24 | 2004-02-12 | Innogenetics N.V. | Fragments of beta-amyloid as targets for vaccination against alzheimer disease |
KR20050071564A (ko) * | 2002-10-09 | 2005-07-07 | 리나트 뉴로사이언스 코퍼레이션 | 아밀로이드 베타 펩티드에 대한 항체를 사용하여알츠하이머병을 치료하는 방법 및 그의 조성물 |
US8697082B2 (en) * | 2002-11-01 | 2014-04-15 | Neotope Biosciences Limited | Prevention and treatment of synucleinopathic and amyloidogenic disease |
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TW200509968A (en) * | 2002-11-01 | 2005-03-16 | Elan Pharm Inc | Prevention and treatment of synucleinopathic disease |
US8506959B2 (en) * | 2002-11-01 | 2013-08-13 | Neotope Biosciences Limited | Prevention and treatment of synucleinopathic and amyloidogenic disease |
US20080014194A1 (en) * | 2003-10-31 | 2008-01-17 | Elan Pharmaceuticals, Inc. | Prevention and Treatment of Synucleinopathic and Amyloidogenic Disease |
WO2004058258A1 (en) * | 2002-12-24 | 2004-07-15 | Neurochem (International) Limited | Therapeutic formulations for the treatment of beta-amyloid related diseases |
DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
RU2390350C2 (ru) * | 2003-02-01 | 2010-05-27 | Ньюралаб Лимитед | Активная иммунизация для создания антител к растворимому а-бета |
US8663650B2 (en) | 2003-02-21 | 2014-03-04 | Ac Immune Sa | Methods and compositions comprising supramolecular constructs |
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US20070010573A1 (en) * | 2003-06-23 | 2007-01-11 | Xianqi Kong | Methods and compositions for treating amyloid-related diseases |
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WO2007035405A2 (en) * | 2005-09-16 | 2007-03-29 | University Of Pittsburgh | In-vivo and in-vitro method for detecting amyloid deposits having at least one amyloidogenic protein |
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US8784810B2 (en) | 2006-04-18 | 2014-07-22 | Janssen Alzheimer Immunotherapy | Treatment of amyloidogenic diseases |
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ES2640095T3 (es) * | 2006-10-02 | 2017-10-31 | Ac Immune S.A. | Anticuerpo humanizado contra beta-amiloide |
EA016568B1 (ru) | 2006-10-12 | 2012-05-30 | Беллус Хелс (Интернэшнл) Лимитед | Способы, соединения, композиции и носители для доставки 3-амино-1-пропансульфоновой кислоты |
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US8147833B2 (en) * | 2007-02-23 | 2012-04-03 | Neotope Biosciences Limited | Prevention and treatment of synucleinopathic and amyloidogenic disease |
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US8003097B2 (en) | 2007-04-18 | 2011-08-23 | Janssen Alzheimer Immunotherapy | Treatment of cerebral amyloid angiopathy |
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EP2231180B1 (de) * | 2008-01-16 | 2016-08-17 | Ben-gurion University Of The Negev Research And Development Authority | Impfstoff für die alzheimerkrankheit |
EP2145898A1 (de) * | 2008-07-15 | 2010-01-20 | CHIESI FARMACEUTICI S.p.A. | Antiamyloide immunogene Zusammensetzungen sowie entsprechende Verfahren und Anwendungen |
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US6905686B1 (en) * | 1997-12-02 | 2005-06-14 | Neuralab Limited | Active immunization for treatment of alzheimer's disease |
PT1161449E (pt) * | 1999-03-04 | 2007-10-12 | Praecis Pharm Inc | Moduladores de agregação do péptido beta-amilóide compreendendo d-aminoácidos |
EP1173480B1 (de) * | 1999-05-05 | 2008-01-16 | Neurochem (International) Limited | Stereoselektive antifibrillogene peptide |
US7060670B1 (en) * | 1999-05-05 | 2006-06-13 | Neurochem (International) Limited | Stereoselective antifibrillogenic peptides and peptidomimetics thereof |
US6787637B1 (en) * | 1999-05-28 | 2004-09-07 | Neuralab Limited | N-Terminal amyloid-β antibodies |
US20070135337A2 (en) * | 1999-11-29 | 2007-06-14 | Neurochem (International) Limited | Vaccine for the Prevention and Treatment of Alzheimer's and Amyloid Related Diseases |
EP1235587A2 (de) * | 1999-11-29 | 2002-09-04 | Neurochem, Inc. | Impfstoffe zur vorbeugung und behandlung von alzheimer und amyloid verwandten krankheiten enthaltend peptide bestehend nur aus d-aminosäuren |
MXPA02006196A (es) * | 1999-12-23 | 2002-12-09 | Neurochem Inc | Compuestos y metodos para modular la angiopatia amiloide cerebral. |
-
2001
- 2001-05-29 US US09/867,847 patent/US20020094335A1/en not_active Abandoned
-
2002
- 2002-05-29 WO PCT/CA2002/000763 patent/WO2002096937A2/en active IP Right Grant
- 2002-05-29 AU AU2002302255A patent/AU2002302255A1/en not_active Abandoned
- 2002-05-29 JP JP2003500116A patent/JP2005508863A/ja not_active Withdrawn
- 2002-05-29 CA CA002449056A patent/CA2449056A1/en not_active Abandoned
- 2002-05-29 AT AT02729715T patent/ATE369380T1/de not_active IP Right Cessation
- 2002-05-29 EP EP02729715A patent/EP1392728B1/de not_active Expired - Lifetime
- 2002-05-29 CN CN02814967XA patent/CN1662554A/zh active Pending
- 2002-05-29 DE DE60221665T patent/DE60221665D1/de not_active Expired - Lifetime
-
2004
- 2004-07-21 US US10/895,646 patent/US20070264276A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CN1662554A (zh) | 2005-08-31 |
CA2449056A1 (en) | 2002-12-05 |
DE60221665D1 (de) | 2007-09-20 |
EP1392728B1 (de) | 2007-08-08 |
WO2002096937A2 (en) | 2002-12-05 |
US20070264276A1 (en) | 2007-11-15 |
WO2002096937A3 (en) | 2003-07-10 |
US20020094335A1 (en) | 2002-07-18 |
AU2002302255A1 (en) | 2002-12-09 |
JP2005508863A (ja) | 2005-04-07 |
EP1392728A2 (de) | 2004-03-03 |
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