ATE366585T1 - Separin inhibitoren, verfahren zu ihren identifizierung und ihre anwendungen - Google Patents

Separin inhibitoren, verfahren zu ihren identifizierung und ihre anwendungen

Info

Publication number
ATE366585T1
ATE366585T1 AT00909162T AT00909162T ATE366585T1 AT E366585 T1 ATE366585 T1 AT E366585T1 AT 00909162 T AT00909162 T AT 00909162T AT 00909162 T AT00909162 T AT 00909162T AT E366585 T1 ATE366585 T1 AT E366585T1
Authority
AT
Austria
Prior art keywords
identifying
separin
inhibitors
applications
sister chromatid
Prior art date
Application number
AT00909162T
Other languages
English (en)
Inventor
Frank Uhlmann
Kim Nasmyth
Jan-Michael Peters
Irene Waizenegger
Sara Buonomo
Rosemary Clyne
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Application granted granted Critical
Publication of ATE366585T1 publication Critical patent/ATE366585T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/70—Mechanisms involved in disease identification
    • G01N2800/7023—(Hyper)proliferation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT00909162T 1999-02-15 2000-02-14 Separin inhibitoren, verfahren zu ihren identifizierung und ihre anwendungen ATE366585T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP99102962A EP1029547A1 (de) 1999-02-15 1999-02-15 Pharmazeutische wirksame stoffe und Verfahren zu zu ihrer Identifizierung

Publications (1)

Publication Number Publication Date
ATE366585T1 true ATE366585T1 (de) 2007-08-15

Family

ID=8237559

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00909162T ATE366585T1 (de) 1999-02-15 2000-02-14 Separin inhibitoren, verfahren zu ihren identifizierung und ihre anwendungen

Country Status (9)

Country Link
US (1) US7410774B1 (de)
EP (2) EP1029547A1 (de)
JP (1) JP4377073B2 (de)
AT (1) ATE366585T1 (de)
CA (1) CA2362794C (de)
DE (1) DE60035490T2 (de)
ES (1) ES2290016T3 (de)
MX (1) MXPA01008214A (de)
WO (1) WO2000048627A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19516776A1 (de) 1995-05-10 1996-11-14 Boehringer Ingelheim Int Chromatin-Regulatorgene
EP1227160A1 (de) * 2001-01-19 2002-07-31 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Verbindungen, die die Trennung von Schwesterchromatiden modulieren, und Verfahren für das Identifizieren dieser Verbindungen
EP1321529A1 (de) * 2001-12-21 2003-06-25 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Verfahren zum Nachweis von Modulatoren von Schwesterchromatid Kohäsion
WO2011100374A2 (en) * 2010-02-09 2011-08-18 Whitehead Institute For Biomedical Research Mediator and cohesin connect gene expression and chromatin architecture
WO2020263909A1 (en) * 2019-06-24 2020-12-30 The Regents Of The University Of California Methods for preparation of active separase

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5486623A (en) * 1993-12-08 1996-01-23 Prototek, Inc. Cysteine protease inhibitors containing heterocyclic leaving groups
EP0956032A4 (de) * 1996-12-20 2002-09-04 Univ Texas Proteine und zusammensetzungen zum modulieren von mitosis
US6004933A (en) * 1997-04-25 1999-12-21 Cortech Inc. Cysteine protease inhibitors
EP1227160A1 (de) * 2001-01-19 2002-07-31 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Verbindungen, die die Trennung von Schwesterchromatiden modulieren, und Verfahren für das Identifizieren dieser Verbindungen

Also Published As

Publication number Publication date
EP1154788B9 (de) 2007-09-12
EP1154788B1 (de) 2007-07-11
JP2002538781A (ja) 2002-11-19
CA2362794C (en) 2010-11-09
DE60035490D1 (de) 2007-08-23
DE60035490T2 (de) 2008-05-08
EP1029547A1 (de) 2000-08-23
WO2000048627A1 (en) 2000-08-24
MXPA01008214A (es) 2003-07-21
JP4377073B2 (ja) 2009-12-02
US7410774B1 (en) 2008-08-12
EP1154788A1 (de) 2001-11-21
ES2290016T3 (es) 2008-02-16
CA2362794A1 (en) 2000-08-24

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