MXPA01008214A - Inhibidores de separina, metodo para identificarlos y usos. - Google Patents

Inhibidores de separina, metodo para identificarlos y usos.

Info

Publication number
MXPA01008214A
MXPA01008214A MXPA01008214A MXPA01008214A MXPA01008214A MX PA01008214 A MXPA01008214 A MX PA01008214A MX PA01008214 A MXPA01008214 A MX PA01008214A MX PA01008214 A MXPA01008214 A MX PA01008214A MX PA01008214 A MXPA01008214 A MX PA01008214A
Authority
MX
Mexico
Prior art keywords
identifying
separin
inhibitors
sister chromatid
compounds
Prior art date
Application number
MXPA01008214A
Other languages
English (en)
Inventor
Frank Uhlmann
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of MXPA01008214A publication Critical patent/MXPA01008214A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/70—Mechanisms involved in disease identification
    • G01N2800/7023—(Hyper)proliferation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
MXPA01008214A 1999-02-15 2000-02-14 Inhibidores de separina, metodo para identificarlos y usos. MXPA01008214A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99102962A EP1029547A1 (en) 1999-02-15 1999-02-15 Pharmaceutically active compounds and method for identifying same
PCT/EP2000/001183 WO2000048627A1 (en) 1999-02-15 2000-02-14 Inhibitors of separin, method for identifying them and uses

Publications (1)

Publication Number Publication Date
MXPA01008214A true MXPA01008214A (es) 2003-07-21

Family

ID=8237559

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA01008214A MXPA01008214A (es) 1999-02-15 2000-02-14 Inhibidores de separina, metodo para identificarlos y usos.

Country Status (9)

Country Link
US (1) US7410774B1 (es)
EP (2) EP1029547A1 (es)
JP (1) JP4377073B2 (es)
AT (1) ATE366585T1 (es)
CA (1) CA2362794C (es)
DE (1) DE60035490T2 (es)
ES (1) ES2290016T3 (es)
MX (1) MXPA01008214A (es)
WO (1) WO2000048627A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19516776A1 (de) 1995-05-10 1996-11-14 Boehringer Ingelheim Int Chromatin-Regulatorgene
EP1227160A1 (en) * 2001-01-19 2002-07-31 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Compounds modulating sister chromatid separation and method for identifying same
EP1321529A1 (en) * 2001-12-21 2003-06-25 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Methods for identifying compounds that modulate sister chromatid cohesion
WO2011100374A2 (en) * 2010-02-09 2011-08-18 Whitehead Institute For Biomedical Research Mediator and cohesin connect gene expression and chromatin architecture
US20220235345A1 (en) * 2019-06-24 2022-07-28 Regents Of The University Of California Methods for preparation of active separase

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5486623A (en) * 1993-12-08 1996-01-23 Prototek, Inc. Cysteine protease inhibitors containing heterocyclic leaving groups
JP2001507226A (ja) * 1996-12-20 2001-06-05 ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム 有糸分裂を調節するためのタンパク質および組成物
US6004933A (en) * 1997-04-25 1999-12-21 Cortech Inc. Cysteine protease inhibitors
EP1227160A1 (en) * 2001-01-19 2002-07-31 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Compounds modulating sister chromatid separation and method for identifying same

Also Published As

Publication number Publication date
JP4377073B2 (ja) 2009-12-02
CA2362794A1 (en) 2000-08-24
ES2290016T3 (es) 2008-02-16
DE60035490D1 (de) 2007-08-23
EP1154788B9 (en) 2007-09-12
WO2000048627A1 (en) 2000-08-24
ATE366585T1 (de) 2007-08-15
DE60035490T2 (de) 2008-05-08
US7410774B1 (en) 2008-08-12
CA2362794C (en) 2010-11-09
EP1154788A1 (en) 2001-11-21
EP1154788B1 (en) 2007-07-11
EP1029547A1 (en) 2000-08-23
JP2002538781A (ja) 2002-11-19

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