ATE366114T1 - Verwendung von anti-prolaktin agentien zur behandlung von krebs - Google Patents

Verwendung von anti-prolaktin agentien zur behandlung von krebs

Info

Publication number
ATE366114T1
ATE366114T1 AT99921843T AT99921843T ATE366114T1 AT E366114 T1 ATE366114 T1 AT E366114T1 AT 99921843 T AT99921843 T AT 99921843T AT 99921843 T AT99921843 T AT 99921843T AT E366114 T1 ATE366114 T1 AT E366114T1
Authority
AT
Austria
Prior art keywords
prolactin
treat cancer
agents
prolactin agents
human
Prior art date
Application number
AT99921843T
Other languages
German (de)
English (en)
Inventor
Wen Y Chen
Thomas E Wagner
Original Assignee
Greenville Hospital System
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26772335&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE366114(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Greenville Hospital System filed Critical Greenville Hospital System
Application granted granted Critical
Publication of ATE366114T1 publication Critical patent/ATE366114T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2257—Prolactin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT99921843T 1998-05-12 1999-05-11 Verwendung von anti-prolaktin agentien zur behandlung von krebs ATE366114T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8512898P 1998-05-12 1998-05-12
US24604199A 1999-02-05 1999-02-05

Publications (1)

Publication Number Publication Date
ATE366114T1 true ATE366114T1 (de) 2007-07-15

Family

ID=26772335

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99921843T ATE366114T1 (de) 1998-05-12 1999-05-11 Verwendung von anti-prolaktin agentien zur behandlung von krebs

Country Status (11)

Country Link
US (2) US7115556B2 (enExample)
EP (2) EP1079851B1 (enExample)
JP (4) JP5259896B2 (enExample)
AT (1) ATE366114T1 (enExample)
AU (1) AU3895299A (enExample)
CA (1) CA2328520C (enExample)
DE (1) DE69936451T2 (enExample)
DK (1) DK1079851T3 (enExample)
ES (1) ES2288777T3 (enExample)
PT (1) PT1079851E (enExample)
WO (1) WO1999058142A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7201905B2 (en) 2000-03-23 2007-04-10 Greenville Hospital System Bi-functional cancer treatment agents
ES2346304T3 (es) * 2002-06-12 2010-10-14 L'oreal Composicion cosmetica de cuidado y/o maquillaje estructurada con polimeros de silicona y agentes organogelificantes, en forma rigida.
CA2509825A1 (en) 2002-12-13 2004-07-01 The Ohio State University Antagonists for human prolactin
CN102319437B (zh) 2002-12-26 2017-10-13 山景医药公司 具有增强的生物学效用的干扰素‑β的聚合物缀合物
US8754031B2 (en) * 2004-03-08 2014-06-17 Oncolix, Inc. Use of prolactin receptor antagonists in combination with an agent that inactivates the HER2/neu signaling pathway
US7507716B2 (en) * 2005-07-06 2009-03-24 Board Of Regents, The University Of Texas System Method for treating pain with prolactin antagonists
WO2008028684A2 (en) * 2006-09-08 2008-03-13 Novo Nordisk A/S Peptides with high affinity for the prolactin receptor
EP2129793A1 (en) 2007-03-20 2009-12-09 Institut National De La Sante Et De La Recherche Medicale Constitutively active mutants of the prolactin receptor
WO2009003732A2 (en) * 2007-07-05 2009-01-08 Novo Nordisk A/S Peptides with high affinity for the prolactin receptor
US20110129873A1 (en) * 2008-04-30 2011-06-02 Monsanto Technology Llc Recombinant DNA Vectors for Expression of Human Prolactin Antagonists
US8648046B2 (en) 2009-02-26 2014-02-11 Oncolix, Inc. Compositions and methods for visualizing and eliminating cancer stem cells
KR101672401B1 (ko) * 2009-02-26 2016-11-16 온코릭스, 아이엔씨. 암 줄기 세포를 가시화하고 제거하기 위한 조성물 및 방법
US8759289B2 (en) * 2010-02-03 2014-06-24 Orbis Health Solutions Llc Method for sensitizing cancer stem cells to cancer therapy
TWI641620B (zh) 2013-08-21 2018-11-21 再生元醫藥公司 抗－ｐｒｌｒ抗體及其用途
US9545451B2 (en) 2013-08-21 2017-01-17 Regeneron Pharmaceuticals, Inc. Anti-PRLR antibodies and methods for killing PRLR-expressing cells
EP3548514A1 (en) 2016-11-29 2019-10-09 Regeneron Pharmaceuticals, Inc. Methods of treating prlr positive breast cancer

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4833516A (en) * 1987-08-03 1989-05-23 International Business Machines Corporation High density memory cell structure having a vertical trench transistor self-aligned with a vertical trench capacitor and fabrication methods therefor
US5350836A (en) 1989-10-12 1994-09-27 Ohio University Growth hormone antagonists
DE69231467T2 (de) 1991-05-10 2001-01-25 Genentech, Inc. Auswählen von agonisten und antagonisten von liganden
US6429186B1 (en) 1991-05-10 2002-08-06 Genentech, Inc. Ligand antagonists for treatment of breast cancer
US5590656A (en) * 1992-09-15 1997-01-07 The Ohio State University Research Foundation Application of peptide/cell receptor kinetics utilizing radiolabeled somatostatin congeners in the in situ, in vivo detection and differentiation of neoplastic tissue
DE4231297A1 (de) 1992-09-18 1994-03-24 Basf Ag Verfahren zur Herstellung von 3-(2'-Oxyethyl)-dihydro-2-(3H)furanonen
JP3983280B2 (ja) * 1993-02-19 2007-09-26 ジェネンテック・インコーポレーテッド 乳ガンの治療のためのリガンドアンタゴニスト
CN1053658C (zh) * 1994-04-06 2000-06-21 日本新药株式会社 氨基芪唑衍生物和药
DE19718721C2 (de) * 1997-05-02 1999-10-07 Siemens Ag DRAM-Zellenanordnung und Verfahren zu deren Herstellung

Also Published As

Publication number Publication date
DK1079851T3 (da) 2007-09-24
JP2011079821A (ja) 2011-04-21
CA2328520A1 (en) 1999-11-18
WO1999058142A1 (en) 1999-11-18
US7115556B2 (en) 2006-10-03
JP5453355B2 (ja) 2014-03-26
CA2328520C (en) 2013-06-25
DE69936451T2 (de) 2008-03-13
JP2002515404A (ja) 2002-05-28
PT1079851E (pt) 2007-10-08
EP1079851B1 (en) 2007-07-04
JP2013224309A (ja) 2013-10-31
US20030022833A1 (en) 2003-01-30
WO1999058142A9 (en) 2000-02-10
ES2288777T3 (es) 2008-01-16
EP2316467A1 (en) 2011-05-04
DE69936451D1 (de) 2007-08-16
EP1079851A4 (en) 2004-03-17
JP2012020996A (ja) 2012-02-02
AU3895299A (en) 1999-11-29
US20070060520A1 (en) 2007-03-15
EP1079851A1 (en) 2001-03-07
JP5259896B2 (ja) 2013-08-07

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