ATE364173T1 - Verwendung von hochwellenzahl-ramanspektroskopie zur messung von gewebe - Google Patents
Verwendung von hochwellenzahl-ramanspektroskopie zur messung von gewebeInfo
- Publication number
- ATE364173T1 ATE364173T1 AT03779036T AT03779036T ATE364173T1 AT E364173 T1 ATE364173 T1 AT E364173T1 AT 03779036 T AT03779036 T AT 03779036T AT 03779036 T AT03779036 T AT 03779036T AT E364173 T1 ATE364173 T1 AT E364173T1
- Authority
- AT
- Austria
- Prior art keywords
- tissue
- raman signal
- detection unit
- signal
- wave number
- Prior art date
Links
- 238000001069 Raman spectroscopy Methods 0.000 title abstract 5
- 238000001514 detection method Methods 0.000 abstract 4
- 239000000835 fiber Substances 0.000 abstract 4
- 239000000523 sample Substances 0.000 abstract 2
- 230000003595 spectral effect Effects 0.000 abstract 2
- 208000037260 Atherosclerotic Plaque Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 238000004458 analytical method Methods 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 239000013307 optical fiber Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/65—Raman scattering
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0075—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
- A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
- A61B5/0086—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters using infrared radiation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/28—Investigating the spectrum
- G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/44—Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
- A61B5/441—Skin evaluation, e.g. for skin disorder diagnosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4848—Monitoring or testing the effects of treatment, e.g. of medication
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/65—Raman scattering
- G01N2021/653—Coherent methods [CARS]
- G01N2021/656—Raman microprobe
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Pathology (AREA)
- Animal Behavior & Ethology (AREA)
- Medical Informatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Surgery (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP02080032 | 2002-12-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE364173T1 true ATE364173T1 (de) | 2007-06-15 |
Family
ID=32405739
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT03779036T ATE364173T1 (de) | 2002-12-02 | 2003-12-02 | Verwendung von hochwellenzahl-ramanspektroskopie zur messung von gewebe |
Country Status (10)
Country | Link |
---|---|
US (1) | US7499153B2 (de) |
EP (2) | EP1821097A1 (de) |
JP (1) | JP4870356B2 (de) |
CN (1) | CN100533127C (de) |
AT (1) | ATE364173T1 (de) |
AU (1) | AU2003285815A1 (de) |
DE (1) | DE60314282T2 (de) |
DK (1) | DK1567852T3 (de) |
ES (1) | ES2289344T3 (de) |
WO (1) | WO2004051242A1 (de) |
Families Citing this family (67)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080105096A1 (en) * | 1999-01-15 | 2008-05-08 | Cutting Edge Designs, Llc | Liquid transport cavity saw blade |
CA2547460A1 (en) | 2003-11-28 | 2005-06-09 | Haishan Zeng | Multimodal detection of tissue abnormalities based on raman and background fluorescence spectroscopy |
DE102004015946B3 (de) * | 2004-03-25 | 2006-01-12 | Ufz-Umweltforschungszentrum Leipzig-Halle Gmbh | Vorrichtung und Verfahren zur Raman-spektroskopischen Charakterisierung eines Prozessmediums |
US7697576B2 (en) | 2004-05-05 | 2010-04-13 | Chem Image Corporation | Cytological analysis by raman spectroscopic imaging |
US7292323B2 (en) * | 2004-11-12 | 2007-11-06 | Alcon, Inc. | Optical fiber detection method and system |
GB0426993D0 (en) * | 2004-12-09 | 2005-01-12 | Council Cent Lab Res Councils | Apparatus for depth-selective raman spectroscopy |
WO2006119166A2 (en) * | 2005-04-29 | 2006-11-09 | The Regents Of The University Of Colorado | Multi-excitation diagnostic systems and methods for classification of tissue |
JP4675149B2 (ja) * | 2005-05-13 | 2011-04-20 | 独立行政法人理化学研究所 | 血管診断用分光プローブ |
US8253936B2 (en) | 2008-08-08 | 2012-08-28 | Chemimage Corporation | Raman characterization of transplant tissue |
GB0606891D0 (en) | 2006-04-05 | 2006-05-17 | Council Cent Lab Res Councils | Raman Analysis Of Pharmaceutical Tablets |
EP2043724A2 (de) * | 2006-07-21 | 2009-04-08 | Prescient Medical, Inc. | Konformer gewebekontaktkatheter |
WO2008051950A2 (en) * | 2006-10-23 | 2008-05-02 | Prescient Medical Inc. | Windowless fiber optic raman spectroscopy probes |
US20120059254A1 (en) * | 2007-03-14 | 2012-03-08 | Wang Lifan | Apparatus and method for phase-space reduction for imaging of fluorescing, scattering and/or absorbing structures |
US7952706B2 (en) * | 2007-05-17 | 2011-05-31 | Prescient Medical, Inc. | Multi-channel fiber optic spectroscopy systems employing integrated optics modules |
WO2008154460A1 (en) * | 2007-06-08 | 2008-12-18 | Prescient Medical, Inc. | Optical catheter configurations combining raman spectroscopy with optical fiber-based low coherence reflectometry |
WO2009014820A1 (en) * | 2007-07-20 | 2009-01-29 | Prescient Medical, Inc. | Wall-contacting intravascular ultrasound probe catheters |
US20090076395A1 (en) * | 2007-09-19 | 2009-03-19 | Prescient Medical, Inc. | Optimized intravascular ultrasound probe catherers |
SE531527C2 (sv) * | 2007-10-01 | 2009-05-12 | Bioresonator Ab | Förfarande vid och en anordning för opåverkad materialundersökning |
JP5198037B2 (ja) * | 2007-11-02 | 2013-05-15 | 株式会社 資生堂 | 皮膚外用剤の有効性評価方法、有効性評価装置、及び有効性評価プログラム |
US20090281536A1 (en) * | 2008-05-09 | 2009-11-12 | Hugh Beckman | Medical Device For Diagnosing and Treating Anomalous Tissue and Method for Doing the Same |
US8416405B2 (en) | 2008-08-08 | 2013-04-09 | Chemimage Corporation | Raman chemical imaging of implantable drug delivery devices |
US20100113906A1 (en) * | 2008-11-06 | 2010-05-06 | Prescient Medical, Inc. | Hybrid basket catheters |
US20100317974A1 (en) * | 2009-01-09 | 2010-12-16 | Research Foundation Of The City University Of New York | Detection of vulnerable plaques by raman spectroscopy |
EP2416708B1 (de) * | 2009-04-01 | 2019-05-08 | Erasmus University Medical Center Rotterdam | Verfahren zur bestimmung von ein oder mehr mutationen |
US20120283530A1 (en) * | 2009-11-17 | 2012-11-08 | Maynard John D | Method and apparatus to detect coronary artery calcification or disease |
US8702321B2 (en) | 2009-12-03 | 2014-04-22 | Eric T. Marple | Filtered fiber optic probe |
US8175423B2 (en) * | 2009-12-03 | 2012-05-08 | Marple Eric T | Filtered fiber optic probe |
US8582096B2 (en) * | 2009-12-18 | 2013-11-12 | The Regents Of The University Of California | System and method for efficient coherence anti-stokes raman scattering endoscopic and intravascular imaging and multimodal imaging |
EP2525704A4 (de) * | 2010-01-22 | 2014-07-23 | British Columbia Cancer Agency | Vorrichtung und verfahren zur kennzeichnung von lungengewebe durch raman-spektroskopie |
DE102010052434A1 (de) * | 2010-11-24 | 2012-05-24 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verfahren und Vorrichtung zur Überwachung einer kryokonservierten biologischen Probe |
US8432542B2 (en) | 2011-01-10 | 2013-04-30 | Eric T. Marple | Fiber optic probes utilizing GRIN lenses for spatially precise optical spectroscopy |
DE102011100507B4 (de) * | 2011-04-29 | 2020-05-14 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Tragbares optisches Analysegerät |
WO2013177061A1 (en) | 2012-05-21 | 2013-11-28 | The Regents Of The University Of Colorado, A Body Corporate | Three-dimensional mapping and therapy of prostate cancer |
US9814448B2 (en) | 2012-05-21 | 2017-11-14 | Precision Biopsy, Inc. | Three-dimensional optical imaging and therapy of prostate cancer |
US10058284B2 (en) * | 2012-12-21 | 2018-08-28 | Volcano Corporation | Simultaneous imaging, monitoring, and therapy |
GB201301280D0 (en) * | 2013-01-24 | 2013-03-06 | Univ St Andrews | Optical apparatus for use with a medical imager |
GB201302886D0 (en) * | 2013-02-19 | 2013-04-03 | Univ Singapore | Diagnostic instrument and method |
EP3003177B1 (de) | 2013-05-31 | 2021-03-10 | Covidien LP | Chirurgische vorrichtung mit einer endeffektorbaugruppe zur gewebeüberwachung bei chirurgischen eingriffen |
EP3019855A4 (de) * | 2013-07-11 | 2017-03-01 | Henry Ford Health System | Vorrichtung und verfahren zum unterscheiden zwischen unterschiedlichen gewebetypen mit spezifischen ramanspektralbereichen |
CN103645170B (zh) * | 2013-12-03 | 2016-03-02 | 北京航空航天大学 | 一种利用拉曼光谱检测肿瘤性质的装置 |
GB201401727D0 (en) * | 2014-01-31 | 2014-03-19 | Univ Bristol | A low background raman probe for optical biopsy of brain tissue |
CN104155002B (zh) * | 2014-07-17 | 2016-03-02 | 中国科学院遥感与数字地球研究所 | 扫描成像光谱仪系统 |
US11304604B2 (en) | 2014-10-29 | 2022-04-19 | Spectral Md, Inc. | Reflective mode multi-spectral time-resolved optical imaging methods and apparatuses for tissue classification |
WO2017074505A1 (en) * | 2015-10-28 | 2017-05-04 | Spectral Md, Inc. | Reflective mode multi-spectral time-resolved optical imaging methods and apparatuses for tissue classification |
US11154186B2 (en) | 2015-07-31 | 2021-10-26 | University Of Utah Research Foundation | Devices, systems, and methods for imaging and treating a selected tissue |
US10161870B2 (en) | 2015-10-05 | 2018-12-25 | Nxgen Partners Ip, Llc | System and method for multi-parameter spectroscopy |
EP3393355A1 (de) * | 2015-12-21 | 2018-10-31 | Erasmus University Medical Center Rotterdam | Optische sonde zur messung einer gewebeprobe |
CN108780042A (zh) * | 2016-01-13 | 2018-11-09 | 尼克根合伙Ip有限责任公司 | 用于多参数光谱的系统和方法 |
US10531818B2 (en) | 2016-01-18 | 2020-01-14 | Erasmus University Medical Center Rotterdam | Tissue sample analysis |
EP3203215B1 (de) | 2016-02-08 | 2019-08-14 | Leibniz-Institut für Astrophysik Potsdam (AIP) | Optische bildgebende spektroskopie von grossflächigen proben |
CN105997000B (zh) * | 2016-05-30 | 2023-04-14 | 福建师范大学 | 一种基于纤维内窥镜的拉曼光谱检测装置及其实现方法 |
WO2018116363A1 (ja) * | 2016-12-19 | 2018-06-28 | オリンパス株式会社 | ラマンプローブおよびラマンスペクトル測定装置 |
CN106770176A (zh) * | 2016-12-26 | 2017-05-31 | 同方威视技术股份有限公司 | 拉曼光谱检测设备和拉曼光谱检测设备的安全监控方法 |
JP7083833B2 (ja) | 2017-02-01 | 2022-06-13 | ユニバーシティ オブ ユタ リサーチ ファウンデーション | 心臓組織マッピングのための装置および方法 |
CN110573066A (zh) | 2017-03-02 | 2019-12-13 | 光谱Md公司 | 用于多光谱截肢部位分析的机器学习系统和技术 |
US11375897B2 (en) | 2017-04-20 | 2022-07-05 | Henry Ford Health System | System and method for characterization of a brain tissue sample using Raman marker regions |
US10684226B2 (en) | 2018-03-09 | 2020-06-16 | Samsung Electronics Co., Ltd. | Raman probe, Raman spectrum obtaining apparatus, and method of obtaining Raman spectrum and detecting distribution of target material using Raman probe |
WO2020047660A1 (en) | 2018-09-04 | 2020-03-12 | Provincial Health Services Authority | Image guided micro-raman spectroscopy |
KR20210099126A (ko) | 2018-12-14 | 2021-08-11 | 스펙트랄 엠디, 인크. | 고정밀도 다중-애퍼쳐 스펙트럼 이미징을 위한 시스템 및 방법 |
EP3893733A4 (de) | 2018-12-14 | 2022-10-12 | Spectral MD, Inc. | Maschinenlernsysteme und verfahren zur beurteilung, heilungsprognose und behandlung von wunden |
US10783632B2 (en) | 2018-12-14 | 2020-09-22 | Spectral Md, Inc. | Machine learning systems and method for assessment, healing prediction, and treatment of wounds |
US10740884B2 (en) | 2018-12-14 | 2020-08-11 | Spectral Md, Inc. | System and method for high precision multi-aperture spectral imaging |
EP3901618A1 (de) * | 2020-03-30 | 2021-10-27 | TimeGate Instruments Oy | Verfahren und vorrichtung zur messung des spektrums von raman-gestreutem licht unter verwendung von zeitgesteuerter detektion |
US11821841B2 (en) | 2021-03-05 | 2023-11-21 | Cytoveris, Inc. | System and method for classification of tissue based on Raman and fluorescence in high-wavenumber Raman spectrum |
US12038383B2 (en) | 2021-03-05 | 2024-07-16 | Cytoveris Inc. | Method and system for identifying tissue type based on peak-fitted parameters in high-wavenumber Raman spectrum |
WO2023008369A1 (ja) * | 2021-07-30 | 2023-02-02 | キヤノン株式会社 | 細胞自家蛍光の画像を用いて細胞を分類する方法及び解析装置 |
CN116077016A (zh) * | 2022-12-22 | 2023-05-09 | 四川大学 | 一种基于拉曼光谱和红外线光谱的便携式信息诊断装置 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5318024A (en) * | 1985-03-22 | 1994-06-07 | Massachusetts Institute Of Technology | Laser endoscope for spectroscopic imaging |
WO1989002718A1 (en) * | 1987-09-24 | 1989-04-06 | Massachusetts Institute Of Technology | Catheter system for imaging |
US5638172A (en) * | 1994-05-27 | 1997-06-10 | Eastman Chemical Company | On-line quantitative analysis of chemical compositions by raman spectrometry |
US5621522A (en) | 1995-04-05 | 1997-04-15 | The United States Of America As Represented By The Secretary Of The Navy | Fiber optic probe for determination of trace levels of organic pollutants using Raman spectroscopy |
US5953477A (en) * | 1995-11-20 | 1999-09-14 | Visionex, Inc. | Method and apparatus for improved fiber optic light management |
JP2000510604A (ja) * | 1996-03-13 | 2000-08-15 | ヴィジョネックス インコーポレイテッド | 改善された光ファイバー光管理のための方法および機器 |
US5911017A (en) | 1996-07-31 | 1999-06-08 | Visionex, Inc. | Fiber optic interface for laser spectroscopic Raman probes |
JP2001515597A (ja) | 1997-03-14 | 2001-09-18 | ローズマウント アナリティカル インコーポレイテッド | 改良されたレイリー後方散乱制御装置および方法 |
US5864397A (en) | 1997-09-15 | 1999-01-26 | Lockheed Martin Energy Research Corporation | Surface-enhanced raman medical probes and system for disease diagnosis and drug testing |
US6205272B1 (en) * | 1998-02-27 | 2001-03-20 | Equitech Int'l Corp. | Fiber optic probe for attenuated total internal reflection spectrophotometry |
JP2000131145A (ja) * | 1998-10-23 | 2000-05-12 | Jasco Corp | 分光分析装置 |
JP3992090B2 (ja) * | 1999-01-11 | 2007-10-17 | 日本分光株式会社 | ラマン分光用プローブ |
US6623977B1 (en) | 1999-11-05 | 2003-09-23 | Real-Time Analyzers, Inc. | Material for surface-enhanced Raman spectroscopy, and SER sensors and method for preparing same |
-
2003
- 2003-12-02 US US10/537,074 patent/US7499153B2/en active Active
- 2003-12-02 EP EP07109398A patent/EP1821097A1/de not_active Withdrawn
- 2003-12-02 DE DE60314282T patent/DE60314282T2/de not_active Expired - Lifetime
- 2003-12-02 WO PCT/NL2003/000815 patent/WO2004051242A1/en active IP Right Grant
- 2003-12-02 CN CNB2003801094716A patent/CN100533127C/zh not_active Expired - Lifetime
- 2003-12-02 DK DK03779036T patent/DK1567852T3/da active
- 2003-12-02 AU AU2003285815A patent/AU2003285815A1/en not_active Abandoned
- 2003-12-02 JP JP2004556982A patent/JP4870356B2/ja not_active Expired - Fee Related
- 2003-12-02 AT AT03779036T patent/ATE364173T1/de active
- 2003-12-02 ES ES03779036T patent/ES2289344T3/es not_active Expired - Lifetime
- 2003-12-02 EP EP03779036A patent/EP1567852B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP1567852B1 (de) | 2007-06-06 |
AU2003285815A1 (en) | 2004-06-23 |
US20060139633A1 (en) | 2006-06-29 |
WO2004051242A1 (en) | 2004-06-17 |
US7499153B2 (en) | 2009-03-03 |
CN100533127C (zh) | 2009-08-26 |
DE60314282T2 (de) | 2008-03-20 |
DE60314282D1 (de) | 2007-07-19 |
JP2006508358A (ja) | 2006-03-09 |
ES2289344T3 (es) | 2008-02-01 |
CN1745294A (zh) | 2006-03-08 |
JP4870356B2 (ja) | 2012-02-08 |
DK1567852T3 (da) | 2007-08-06 |
EP1567852A1 (de) | 2005-08-31 |
EP1821097A1 (de) | 2007-08-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE364173T1 (de) | Verwendung von hochwellenzahl-ramanspektroskopie zur messung von gewebe | |
US6006001A (en) | Fiberoptic assembly useful in optical spectroscopy | |
US9804092B2 (en) | Integrated spectral probe for raman, reflectance and fluorescence spectral measurements | |
US10531790B2 (en) | Method and system of spectrally encoded imaging | |
Latka et al. | Fiber optic probes for linear and nonlinear Raman applications–Current trends and future development | |
JP3737579B2 (ja) | 歯の状態の認識装置 | |
US6069689A (en) | Apparatus and methods relating to optical systems for diagnosis of skin diseases | |
US8804115B2 (en) | Systems and methods for performing optical spectroscopy using a self-calibrating fiber optic probe | |
US7184142B2 (en) | Raman probe and Raman spectrum measuring apparatus utilizing the same | |
US20030156788A1 (en) | Method and device for recognizing dental caries, plaque, concrements or bacterial attacks | |
WO2004064627B1 (en) | In vivo raman endoscopic probe and methods of use | |
JP5476547B2 (ja) | ラマン散乱測定装置 | |
CN107941782B (zh) | 可内窥光纤拉曼探针及检测装置 | |
ATE442079T1 (de) | Verfahren zum nicht invasiven messen von karotenoiden und verwandten chemischen substanzen in biologischem gewebe | |
JP4361822B2 (ja) | 目的物の成分濃度測定方法及び装置 | |
Katagiri et al. | High axial resolution Raman probe made of a single hollow optical fiber | |
US20090153852A1 (en) | Optical fiber for spectroscopic analysis system | |
Maryam et al. | Mobile multi-configuration clinical translational Raman system for oral cancer application | |
Ribeiro et al. | A preliminary investigation of a spectroscopic technique for the diagnosis of natural caries lesions | |
Zeng et al. | Raman spectroscopy for in vivo tissue analysis and diagnosis, from instrument development to clinical applications | |
CN216622169U (zh) | 一种基于荧光和拉曼融合技术的皮肤组织光谱检测装置 | |
WO2018116363A1 (ja) | ラマンプローブおよびラマンスペクトル測定装置 | |
CN101903762B (zh) | 光纤探针 | |
JP2017153841A (ja) | 歯垢検出装置及び歯ブラシ | |
RU2506049C1 (ru) | Устройство диагностики рака кожи |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 1567852 Country of ref document: EP |