ATE36158T1 - Rueckgewinnung von 6-fluoro-4-chromanon aus 6fluoro-4-ureido-chroman-4-carboxylsaeure. - Google Patents
Rueckgewinnung von 6-fluoro-4-chromanon aus 6fluoro-4-ureido-chroman-4-carboxylsaeure.Info
- Publication number
- ATE36158T1 ATE36158T1 AT85306741T AT85306741T ATE36158T1 AT E36158 T1 ATE36158 T1 AT E36158T1 AT 85306741 T AT85306741 T AT 85306741T AT 85306741 T AT85306741 T AT 85306741T AT E36158 T1 ATE36158 T1 AT E36158T1
- Authority
- AT
- Austria
- Prior art keywords
- fluoro
- chromanone
- 6fluoro
- chroman
- ureido
- Prior art date
Links
- SWBBIJZMIGAZHW-UHFFFAOYSA-N 6-fluoro-2,3-dihydrochromen-4-one Chemical compound O1CCC(=O)C2=CC(F)=CC=C21 SWBBIJZMIGAZHW-UHFFFAOYSA-N 0.000 title abstract 4
- 239000002253 acid Substances 0.000 title 1
- 238000011084 recovery Methods 0.000 title 1
- PLFOGGJHQOVQAF-LLVKDONJSA-N (4r)-4-(carbamoylamino)-6-fluoro-2,3-dihydrochromene-4-carboxylic acid Chemical compound C1=C(F)C=C2[C@@](NC(=O)N)(C(O)=O)CCOC2=C1 PLFOGGJHQOVQAF-LLVKDONJSA-N 0.000 abstract 3
- 230000004048 modification Effects 0.000 abstract 2
- 238000012986 modification Methods 0.000 abstract 2
- LXANPKRCLVQAOG-NSHDSACASA-N sorbinil Chemical compound C12=CC(F)=CC=C2OCC[C@@]21NC(=O)NC2=O LXANPKRCLVQAOG-NSHDSACASA-N 0.000 abstract 2
- 229950004311 sorbinil Drugs 0.000 abstract 2
- 229940118148 Aldose reductase inhibitor Drugs 0.000 abstract 1
- 239000003288 aldose reductase inhibitor Substances 0.000 abstract 1
- 239000006227 byproduct Substances 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- MNQZXJOMYWMBOU-UHFFFAOYSA-N glyceraldehyde Chemical compound OCC(O)C=O MNQZXJOMYWMBOU-UHFFFAOYSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 239000012286 potassium permanganate Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/42—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4
- C07D311/44—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 with one hydrogen atom in position 3
- C07D311/54—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 with one hydrogen atom in position 3 substituted in the carbocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Control And Safety Of Cranes (AREA)
- Manufacture, Treatment Of Glass Fibers (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Jellies, Jams, And Syrups (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Fats And Perfumes (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/655,006 US4551542A (en) | 1984-09-26 | 1984-09-26 | Regeneration of 6-fluoro-4-chromanone from 6-fluoro-4-ureidochroman-4-carboxylic acid |
| CN85106603.8A CN1004000B (zh) | 1984-09-26 | 1985-08-31 | 由6-氟代-4-脲基苯并二氢吡喃-4-羧酸再生为6-氟代苯并二氢吡喃-4-酮的方法 |
| EP85306741A EP0179570B1 (de) | 1984-09-26 | 1985-09-23 | Rückgewinnung von 6-Fluoro-4-chromanon aus 6-Fluoro-4-ureido-chroman-4-carboxylsäure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE36158T1 true ATE36158T1 (de) | 1988-08-15 |
Family
ID=76224744
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT85306741T ATE36158T1 (de) | 1984-09-26 | 1985-09-23 | Rueckgewinnung von 6-fluoro-4-chromanon aus 6fluoro-4-ureido-chroman-4-carboxylsaeure. |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US4551542A (de) |
| EP (1) | EP0179570B1 (de) |
| JP (1) | JPS6185376A (de) |
| KR (1) | KR870000584B1 (de) |
| CN (1) | CN1004000B (de) |
| AT (1) | ATE36158T1 (de) |
| AU (1) | AU554303B2 (de) |
| CA (1) | CA1215378A (de) |
| DD (1) | DD239594A5 (de) |
| DE (1) | DE3564111D1 (de) |
| DK (1) | DK433685A (de) |
| ES (1) | ES8604848A1 (de) |
| FI (1) | FI853684A7 (de) |
| GR (1) | GR852286B (de) |
| HU (1) | HU196387B (de) |
| IL (1) | IL76488A (de) |
| NO (1) | NO853769L (de) |
| PH (1) | PH20691A (de) |
| PL (1) | PL147214B1 (de) |
| PT (1) | PT81184B (de) |
| SU (1) | SU1340586A3 (de) |
| YU (1) | YU43885B (de) |
| ZA (1) | ZA857379B (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11498018B2 (en) * | 2017-11-27 | 2022-11-15 | Vasilios (Bill) Panagiotakopoulos | Extraction and purification of cannabinoid compounds |
| CN112939793B (zh) * | 2021-02-03 | 2022-07-08 | 浙江普洛康裕制药有限公司 | 麻黄碱和伪麻黄碱工业生产过程中母液中活性成分的回收利用方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4117230A (en) * | 1976-10-18 | 1978-09-26 | Pfizer Inc. | Hydantoin derivatives as therapeutic agents |
| US4147795A (en) * | 1977-02-11 | 1979-04-03 | Pfizer Inc. | Hydantoin derivatives as therapeutic agents |
| US4130714A (en) * | 1977-05-23 | 1978-12-19 | Pfizer Inc. | Hydantoin therapeutic agents |
| US4210663A (en) * | 1978-11-08 | 1980-07-01 | Pfizer Inc. | Halogen substituted benzopyran- and benzothiopyran-4-carboxylic acids |
| US4286098A (en) * | 1980-03-28 | 1981-08-25 | Pfizer Inc. | Process for the preparation of chiral hydantoins |
| US4348526A (en) * | 1980-03-28 | 1982-09-07 | Pfizer Inc. | Intermediates in the preparation of chiral hydantoins |
| EP0065392B1 (de) * | 1981-05-13 | 1985-02-13 | Imperial Chemical Industries Plc | Pharmazeutische Zubereitungen, die Spirosuccinimidderivate enthalten |
| US4431828A (en) * | 1982-11-10 | 1984-02-14 | Pfizer Inc. | Regeneration of 6-fluoro-4-chromanone from by-products in the synthesis of sorbinil |
| US4435578A (en) * | 1982-11-10 | 1984-03-06 | Pfizer Inc. | Sorbinil by optical resolution of precursor 6-fluoro-4-ureidochroman-4-carboxylic acid |
-
1984
- 1984-09-26 US US06/655,006 patent/US4551542A/en not_active Expired - Lifetime
-
1985
- 1985-06-27 CA CA000485501A patent/CA1215378A/en not_active Expired
- 1985-08-31 CN CN85106603.8A patent/CN1004000B/zh not_active Expired
- 1985-09-19 GR GR852286A patent/GR852286B/el unknown
- 1985-09-23 DE DE8585306741T patent/DE3564111D1/de not_active Expired
- 1985-09-23 EP EP85306741A patent/EP0179570B1/de not_active Expired
- 1985-09-23 AT AT85306741T patent/ATE36158T1/de not_active IP Right Cessation
- 1985-09-24 ES ES547256A patent/ES8604848A1/es not_active Expired
- 1985-09-24 IL IL76488A patent/IL76488A/xx unknown
- 1985-09-24 PT PT81184A patent/PT81184B/pt unknown
- 1985-09-24 PL PL1985255500A patent/PL147214B1/pl unknown
- 1985-09-24 DD DD85280951A patent/DD239594A5/de not_active IP Right Cessation
- 1985-09-25 KR KR1019850007042A patent/KR870000584B1/ko not_active Expired
- 1985-09-25 NO NO853769A patent/NO853769L/no unknown
- 1985-09-25 YU YU1531/85A patent/YU43885B/xx unknown
- 1985-09-25 ZA ZA857379A patent/ZA857379B/xx unknown
- 1985-09-25 HU HU853644A patent/HU196387B/hu not_active IP Right Cessation
- 1985-09-25 PH PH32850A patent/PH20691A/en unknown
- 1985-09-25 DK DK433685A patent/DK433685A/da not_active Application Discontinuation
- 1985-09-25 FI FI853684A patent/FI853684A7/fi not_active IP Right Cessation
- 1985-09-25 SU SU853952444A patent/SU1340586A3/ru active
- 1985-09-25 AU AU47884/85A patent/AU554303B2/en not_active Ceased
- 1985-09-26 JP JP60213619A patent/JPS6185376A/ja active Granted
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |