ATE35266T1 - 3-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-5,6dihydro-5-methyl-6-oxo-4h-imidazo(1,5a)(1,4)benzodiazepin, verfahren zu seiner herstellung und pharmazeutische zubereitungen. - Google Patents

3-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-5,6dihydro-5-methyl-6-oxo-4h-imidazo(1,5a)(1,4)benzodiazepin, verfahren zu seiner herstellung und pharmazeutische zubereitungen.

Info

Publication number
ATE35266T1
ATE35266T1 AT86102951T AT86102951T ATE35266T1 AT E35266 T1 ATE35266 T1 AT E35266T1 AT 86102951 T AT86102951 T AT 86102951T AT 86102951 T AT86102951 T AT 86102951T AT E35266 T1 ATE35266 T1 AT E35266T1
Authority
AT
Austria
Prior art keywords
oxadiazol
imidazo
cyclopropyl
oxo
methyl
Prior art date
Application number
AT86102951T
Other languages
English (en)
Inventor
Frank Waetjen
Mogens Engelstoft
John Bondo Hansen
Leif Helth Jensen
Original Assignee
Ferrosan As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK220485A external-priority patent/DK220485D0/da
Priority claimed from DK365985A external-priority patent/DK365985D0/da
Priority claimed from DK476985A external-priority patent/DK476985D0/da
Application filed by Ferrosan As filed Critical Ferrosan As
Application granted granted Critical
Publication of ATE35266T1 publication Critical patent/ATE35266T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Polyethers (AREA)
  • Phenolic Resins Or Amino Resins (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
AT86102951T 1985-05-17 1986-03-06 3-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-5,6dihydro-5-methyl-6-oxo-4h-imidazo(1,5a)(1,4)benzodiazepin, verfahren zu seiner herstellung und pharmazeutische zubereitungen. ATE35266T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DK220485A DK220485D0 (da) 1985-05-17 1985-05-17 Nye oxadiazolylimidazobenzodiazepinderivater samt fremgangsmaade tilfremstilling heraf
DK365985A DK365985D0 (da) 1985-08-12 1985-08-12 Nye oxadiazolylimidazobenzodiazepinderivater samt fremgangsmaade tilfremstilling heraf
DK476985A DK476985D0 (da) 1985-10-17 1985-10-17 Fremgangsmaade til fremstilling af oxadiazolylderivater af imidazobenzodiazepiner og mellemprodukt til brug ved fremgangsmaaden
EP86102951A EP0201678B1 (de) 1985-05-17 1986-03-06 3-(5-Cyclopropyl-1,2,4-oxadiazol-3-yl)-5,6-dihydro-5-methyl-6-oxo-4H-imidazo(1,5-a)(1,4)benzodiazepin, Verfahren zu seiner Herstellung und pharmazeutische Zubereitungen

Publications (1)

Publication Number Publication Date
ATE35266T1 true ATE35266T1 (de) 1988-07-15

Family

ID=27221528

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86102951T ATE35266T1 (de) 1985-05-17 1986-03-06 3-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-5,6dihydro-5-methyl-6-oxo-4h-imidazo(1,5a)(1,4)benzodiazepin, verfahren zu seiner herstellung und pharmazeutische zubereitungen.

Country Status (16)

Country Link
US (2) US4622320A (de)
EP (1) EP0201678B1 (de)
JP (1) JPH01279877A (de)
AT (1) ATE35266T1 (de)
AU (2) AU590273B2 (de)
CA (2) CA1256864A (de)
DE (2) DE3660331D1 (de)
DK (2) DK157194C (de)
ES (1) ES8707205A1 (de)
FI (1) FI82049C (de)
GR (1) GR861260B (de)
IE (1) IE59494B1 (de)
IL (1) IL78790A (de)
NO (1) NO163228C (de)
NZ (1) NZ216202A (de)
PT (1) PT82594B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3587913D1 (de) * 1984-01-19 1994-10-06 Hoffmann La Roche Imidazodiazepin-Derivate.
US4745112A (en) * 1985-05-17 1988-05-17 A/S Ferrosan Oxadiazolylimidazobenzodiazepine, compositions, and method III
US4622320A (en) * 1985-05-17 1986-11-11 As Ferrosan Oxadiazolylimidazobenzodiazepine, compositions, and method
US4771051A (en) * 1985-05-17 1988-09-13 A/S Ferrosan 3-substituted-4,5-dihydro-5-oxo imidazoquinazolines, their preparation, and their use in treating benzodiazepin receptor-related ailments
DE3686723T2 (de) * 1985-10-17 1993-04-01 Novonordisk As Oxadiazolylacetonitrile, ihre herstellung und anwendung.
DK174086D0 (da) * 1986-04-16 1986-04-16 Ferrosan As Nye benzodiazepinderivater samt fremgangsmaade til fremstilling af samme
DK522187D0 (da) * 1987-10-06 1987-10-06 Ferrosan As Imidozothienopyrimidiner, deres fremstilling og anvendelse
GB8823475D0 (en) * 1988-10-06 1988-11-16 Merck Sharp & Dohme Chemical compounds
CA2143246C (en) * 1994-03-16 2000-08-22 Thierry Godel Imidazodiazepines
FI101305B (fi) * 1996-03-18 1998-05-29 Map Medical Technologies Oy Radiofarmaseuttisena aineena käyttökelpoiset radiojodatut bentsodiatse piini-johdannaiset ja niiden käyttö diagnostiikassa
US20090054412A1 (en) * 2007-08-20 2009-02-26 John Alan Kemp Treatment of Sleep Disorders
CA2696703C (en) 2007-08-20 2016-07-26 Evotec Neurosciences Gmbh Treatment of sleep disorders

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4031029A (en) * 1975-07-02 1977-06-21 General Electric Company Process for producing uranium oxide rich compositions from uranium hexafluoride using fluid injection into the reaction zone
CA1143728A (en) * 1979-10-04 1983-03-29 Max Gerecke Imidazodiazepine derivatives
JPS57123180A (en) * 1980-12-17 1982-07-31 Schering Ag 3-substituted beta-carboline, manufacture and psychotropic drug containing same
DK151808C (da) * 1982-11-16 1988-06-20 Ferrosan As Analogifremgangsmaade til fremstilling af oxadiazolylimidazo-oe1,4aa-benzodiazepinderivater
DE3587913D1 (de) * 1984-01-19 1994-10-06 Hoffmann La Roche Imidazodiazepin-Derivate.
AU587802B2 (en) * 1985-03-08 1989-08-31 Ferrosan A/S Novel oxadiazolyl imidazobenzodiazepine derivatives and methods of preparing such compounds
US4622320A (en) * 1985-05-17 1986-11-11 As Ferrosan Oxadiazolylimidazobenzodiazepine, compositions, and method
DE3686723T2 (de) * 1985-10-17 1993-04-01 Novonordisk As Oxadiazolylacetonitrile, ihre herstellung und anwendung.
DK174086D0 (da) * 1986-04-16 1986-04-16 Ferrosan As Nye benzodiazepinderivater samt fremgangsmaade til fremstilling af samme

Also Published As

Publication number Publication date
NO163228C (no) 1990-04-25
FI862061L (fi) 1986-11-18
IE861306L (en) 1986-11-17
ES555035A0 (es) 1987-07-16
DK160097B (da) 1991-01-28
PT82594B (pt) 1988-03-03
GR861260B (en) 1986-09-10
AU614407B2 (en) 1991-08-29
FI82049C (fi) 1991-01-10
NO861954L (no) 1986-11-18
EP0201678A1 (de) 1986-11-20
CA1256863A (en) 1989-07-04
DE201678T1 (de) 1987-02-26
AU590273B2 (en) 1989-11-02
AU3933389A (en) 1989-11-23
DK63288D0 (da) 1988-02-08
FI862061A0 (fi) 1986-05-16
US4622321A (en) 1986-11-11
DK231686A (da) 1986-11-18
NZ216202A (en) 1989-08-29
DK63288A (da) 1988-02-08
DK157194C (da) 1990-04-23
IE59494B1 (en) 1994-02-23
US4622320A (en) 1986-11-11
FI82049B (fi) 1990-09-28
CA1256864A (en) 1989-07-04
EP0201678B1 (de) 1988-06-22
DK160097C (da) 1991-06-24
NO163228B (no) 1990-01-15
ES8707205A1 (es) 1987-07-16
PT82594A (en) 1986-06-01
DE3660331D1 (en) 1988-07-28
DK157194B (da) 1989-11-20
DK231686D0 (da) 1986-05-16
IL78790A0 (en) 1986-08-31
IL78790A (en) 1990-01-18
AU5742986A (en) 1986-11-20
JPH01279877A (ja) 1989-11-10

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner
REN Ceased due to non-payment of the annual fee