ATE350486T1 - Durch mechanischen stress induzierte gene, deren expressionsprodukte und deren verwendung. - Google Patents
Durch mechanischen stress induzierte gene, deren expressionsprodukte und deren verwendung.Info
- Publication number
- ATE350486T1 ATE350486T1 AT99923223T AT99923223T ATE350486T1 AT E350486 T1 ATE350486 T1 AT E350486T1 AT 99923223 T AT99923223 T AT 99923223T AT 99923223 T AT99923223 T AT 99923223T AT E350486 T1 ATE350486 T1 AT E350486T1
- Authority
- AT
- Austria
- Prior art keywords
- genes
- expression products
- mechanical stress
- osteoporosis
- processes
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 5
- 238000000034 method Methods 0.000 abstract 5
- 208000001132 Osteoporosis Diseases 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 2
- 230000002265 prevention Effects 0.000 abstract 2
- 238000003745 diagnosis Methods 0.000 abstract 1
- 239000000523 sample Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8567398P | 1998-05-15 | 1998-05-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE350486T1 true ATE350486T1 (de) | 2007-01-15 |
Family
ID=22193209
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99923223T ATE350486T1 (de) | 1998-05-15 | 1999-05-14 | Durch mechanischen stress induzierte gene, deren expressionsprodukte und deren verwendung. |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1082463B1 (https=) |
| JP (1) | JP2002535956A (https=) |
| AT (1) | ATE350486T1 (https=) |
| AU (1) | AU4004699A (https=) |
| CA (1) | CA2332150A1 (https=) |
| DE (1) | DE69934688T2 (https=) |
| IL (2) | IL139637A0 (https=) |
| WO (1) | WO1999060164A1 (https=) |
| ZA (1) | ZA200006613B (https=) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020151514A1 (en) * | 1998-05-11 | 2002-10-17 | Paz Einat | Genes associated with mechanical stress, expression products therefrom, and uses thereof |
| US7259253B2 (en) | 1999-05-14 | 2007-08-21 | Quark Biotech, Inc. | Genes associated with mechanical stress, expression products therefrom, and uses thereof |
| US7034132B2 (en) | 2001-06-04 | 2006-04-25 | Anderson David W | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
| US6986988B2 (en) | 1999-10-06 | 2006-01-17 | Quark Biotech, Inc. | Method for enrichment of natural antisense messenger RNA |
| US6528262B1 (en) | 1999-10-06 | 2003-03-04 | Quark Biotech, Inc. | Method for enrichment of natural antisense messenger RNA |
| US6468749B1 (en) | 2000-03-30 | 2002-10-22 | Quark Biotech, Inc. | Sequence-dependent gene sorting techniques |
| AU2002221046A1 (en) * | 2000-12-06 | 2002-06-18 | Takara Shuzo Co., Ltd. | Functional dna array |
| WO2002077019A1 (en) * | 2001-03-23 | 2002-10-03 | Dana Farber Cancer Institute,Inc. | Methods and compositions for modulating tumor suppression |
| US20030191073A1 (en) | 2001-11-07 | 2003-10-09 | Challita-Eid Pia M. | Nucleic acid and corresponding protein entitled 161P2F10B useful in treatment and detection of cancer |
| BE1014949A3 (fr) | 2001-08-14 | 2004-07-06 | Probiox | Procede de detection de stress oxydant et trousse pour sa mise en oeuvre. |
| JP4200100B2 (ja) | 2001-11-07 | 2008-12-24 | アジェンシス，インコーポレイテッド | 癌の処置および検出において有用な１６１ｐ２ｆ１０ｂと称される、核酸および対応タンパク質 |
| JP2007525953A (ja) * | 2003-06-06 | 2007-09-13 | ワイス | 骨リモデリングを調節する物質を同定するための方法および材料、ならびにそれによって同定された物質 |
| CA2582607C (en) | 2004-10-08 | 2016-07-12 | Clinuvel Pharmaceuticals Limited | Compositions and methods for inducing melanogenesis in a subject |
| RU2413735C2 (ru) | 2005-03-31 | 2011-03-10 | Эдженсис, Инк. | Антитела и родственные молекулы, связывающиеся с белками 161p2f10b |
| US8350009B2 (en) | 2005-03-31 | 2013-01-08 | Agensys, Inc. | Antibodies and related molecules that bind to 161P2F10B proteins |
| US20070178115A1 (en) | 2005-08-15 | 2007-08-02 | Tang De-Chu C | Immunization of avians by administration of non-replicating vectored vaccines |
| FR2893328B1 (fr) * | 2005-11-17 | 2014-01-31 | Lvmh Rech | Procede pour depister des marqueurs impliques dans la resistance de keratinocytes a des deformations mecaniques. |
| DK2865422T3 (da) | 2006-08-31 | 2017-11-20 | Clinuvel Pharmaceuticals Ltd | Alpha-msh-derivater til behandling af fotodermatoser |
| DK2957292T3 (en) | 2008-03-27 | 2018-01-22 | Clinuvel Pharmaceuticals Ltd | VITILIGOTERAPHY |
| CN102844045A (zh) | 2010-02-08 | 2012-12-26 | 艾更斯司股份有限公司 | 结合于161p2f10b蛋白的抗体药物偶联物(adc) |
| EP2487185A1 (en) | 2011-02-11 | 2012-08-15 | Clinuvel Pharmaceuticals Limited | Hexapeptide with improved activity in the repair of cellular DNA of dermal cells |
| ES2645156T3 (es) | 2011-03-21 | 2017-12-04 | Altimmune Inc. | Agente terapéutico inmunológico de acción rápida y prolongada |
| MX350096B (es) | 2011-08-12 | 2017-08-25 | Merial Inc | Preservación asistida con vacío de productos biológicos, en particular de vacunas. |
| WO2014012090A1 (en) | 2012-07-13 | 2014-01-16 | The Broad Institute, Inc. | Molecular sleds comprising a positively-charged amino acid sequence and a molecular cargo and uses thereof |
| AU2013293270B2 (en) | 2012-07-25 | 2018-08-16 | Massachusetts Institute Of Technology | Inducible DNA binding proteins and genome perturbation tools and applications thereof |
| WO2014121104A1 (en) * | 2013-01-31 | 2014-08-07 | The Regents Of The University Of California | Pooled genetic perturbation effects |
| US11332719B2 (en) | 2013-03-15 | 2022-05-17 | The Broad Institute, Inc. | Recombinant virus and preparations thereof |
| WO2015057671A1 (en) | 2013-10-14 | 2015-04-23 | The Broad Institute, Inc. | Artificial transcription factors comprising a sliding domain and uses thereof |
| JP6545084B2 (ja) * | 2015-11-11 | 2019-07-17 | 株式会社Adeka | 潤滑油組成物及びその製造方法 |
| EP3640329A1 (en) * | 2018-10-18 | 2020-04-22 | Fundación del Sector Público Estatal Centro Nacional de Investigaciones Oncológicas Carlos III (F.S.P. CNIO) | Gene editing based cancer treatment |
| US20240254510A1 (en) * | 2021-03-19 | 2024-08-01 | Washington University | Methods for generating mechanically-responsive cells and uses thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX9204303A (es) * | 1991-07-23 | 1993-11-01 | Rhone Poulenc Rorer Int | Factor regulador del crecimiento de osteoclasto. |
| US5445941A (en) * | 1993-06-21 | 1995-08-29 | Eli Lilly And Company | Method for screening anti-osteoporosis agents |
| US5763416A (en) * | 1994-02-18 | 1998-06-09 | The Regent Of The University Of Michigan | Gene transfer into bone cells and tissues |
| US5834248A (en) * | 1995-02-10 | 1998-11-10 | Millennium Pharmaceuticals Inc. | Compositions and methods using rchd534, a gene uregulated by shear stress |
| US5861249A (en) * | 1996-04-23 | 1999-01-19 | Cold Spring Harbor Laboratory | Assays and reagents for identifying modulators of cdc25-mediated mitotic activation |
-
1999
- 1999-05-14 IL IL13963799A patent/IL139637A0/xx unknown
- 1999-05-14 EP EP99923223A patent/EP1082463B1/en not_active Expired - Lifetime
- 1999-05-14 JP JP2000549770A patent/JP2002535956A/ja active Pending
- 1999-05-14 AU AU40046/99A patent/AU4004699A/en not_active Abandoned
- 1999-05-14 DE DE69934688T patent/DE69934688T2/de not_active Expired - Fee Related
- 1999-05-14 AT AT99923223T patent/ATE350486T1/de not_active IP Right Cessation
- 1999-05-14 WO PCT/US1999/011066 patent/WO1999060164A1/en not_active Ceased
- 1999-05-14 CA CA002332150A patent/CA2332150A1/en not_active Abandoned
-
2000
- 2000-11-13 IL IL139637A patent/IL139637A/en active IP Right Grant
- 2000-11-14 ZA ZA200006613A patent/ZA200006613B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1082463A1 (en) | 2001-03-14 |
| EP1082463B1 (en) | 2007-01-03 |
| WO1999060164A1 (en) | 1999-11-25 |
| AU4004699A (en) | 1999-12-06 |
| IL139637A0 (en) | 2002-02-10 |
| DE69934688T2 (de) | 2007-10-18 |
| EP1082463A4 (en) | 2003-05-21 |
| ZA200006613B (en) | 2002-02-14 |
| IL139637A (en) | 2009-09-22 |
| JP2002535956A (ja) | 2002-10-29 |
| DE69934688D1 (de) | 2007-02-15 |
| CA2332150A1 (en) | 1999-11-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |