ATE350015T1 - Mikropartikelzusammensetzungen und verfahren zu ihrer herstellung - Google Patents

Mikropartikelzusammensetzungen und verfahren zu ihrer herstellung

Info

Publication number
ATE350015T1
ATE350015T1 AT01975585T AT01975585T ATE350015T1 AT E350015 T1 ATE350015 T1 AT E350015T1 AT 01975585 T AT01975585 T AT 01975585T AT 01975585 T AT01975585 T AT 01975585T AT E350015 T1 ATE350015 T1 AT E350015T1
Authority
AT
Austria
Prior art keywords
antigens
microparticles
methods
lactide
daltons
Prior art date
Application number
AT01975585T
Other languages
German (de)
English (en)
Inventor
Jia-Hwa Fang
Manmohan Singh
Derek O'hagan
Maninder Hora
Original Assignee
Novartis Vaccines & Diagnostic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Vaccines & Diagnostic filed Critical Novartis Vaccines & Diagnostic
Application granted granted Critical
Publication of ATE350015T1 publication Critical patent/ATE350015T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • AIDS & HIV (AREA)
  • Pulmonology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT01975585T 2000-09-28 2001-09-28 Mikropartikelzusammensetzungen und verfahren zu ihrer herstellung ATE350015T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US23607700P 2000-09-28 2000-09-28

Publications (1)

Publication Number Publication Date
ATE350015T1 true ATE350015T1 (de) 2007-01-15

Family

ID=22888043

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01975585T ATE350015T1 (de) 2000-09-28 2001-09-28 Mikropartikelzusammensetzungen und verfahren zu ihrer herstellung

Country Status (14)

Country Link
US (2) US6753015B2 (enExample)
EP (1) EP1322292B1 (enExample)
JP (2) JP2004509914A (enExample)
CN (2) CN101428006A (enExample)
AT (1) ATE350015T1 (enExample)
AU (2) AU9489801A (enExample)
BR (1) BR0114304A (enExample)
CA (1) CA2420621C (enExample)
DE (1) DE60125795T2 (enExample)
ES (1) ES2278786T3 (enExample)
MX (1) MXPA03002643A (enExample)
RU (1) RU2257198C2 (enExample)
WO (1) WO2002026212A2 (enExample)
ZA (1) ZA200301743B (enExample)

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Also Published As

Publication number Publication date
CA2420621A1 (en) 2002-04-04
US7846479B2 (en) 2010-12-07
JP2013147514A (ja) 2013-08-01
RU2257198C2 (ru) 2005-07-27
ES2278786T3 (es) 2007-08-16
US20040156913A1 (en) 2004-08-12
AU9489801A (en) 2002-04-08
BR0114304A (pt) 2003-07-29
DE60125795D1 (de) 2007-02-15
ZA200301743B (en) 2004-10-04
CN101428006A (zh) 2009-05-13
AU2001294898B2 (en) 2006-02-02
MXPA03002643A (es) 2003-06-19
EP1322292B1 (en) 2007-01-03
US6753015B2 (en) 2004-06-22
DE60125795T2 (de) 2007-10-18
CA2420621C (en) 2011-05-24
JP2004509914A (ja) 2004-04-02
US20020136776A1 (en) 2002-09-26
CN1535140A (zh) 2004-10-06
EP1322292A2 (en) 2003-07-02
WO2002026212A2 (en) 2002-04-04
WO2002026212A3 (en) 2003-03-27

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