ATE349449T1 - Für die therapie geeignete triazolverbindungen - Google Patents

Für die therapie geeignete triazolverbindungen

Info

Publication number
ATE349449T1
ATE349449T1 AT04709303T AT04709303T ATE349449T1 AT E349449 T1 ATE349449 T1 AT E349449T1 AT 04709303 T AT04709303 T AT 04709303T AT 04709303 T AT04709303 T AT 04709303T AT E349449 T1 ATE349449 T1 AT E349449T1
Authority
AT
Austria
Prior art keywords
therapy
compounds suitable
triazole compounds
triazole
compounds
Prior art date
Application number
AT04709303T
Other languages
German (de)
English (en)
Inventor
Justin Bryans
Patrick Johnson
Thomas Ryckmans
Alan Stobie
Rachel Jane Russell
Christopher Peter Wayman
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0303852.8A external-priority patent/GB0303852D0/en
Priority claimed from GBGB0317227.7A external-priority patent/GB0317227D0/en
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of ATE349449T1 publication Critical patent/ATE349449T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
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    • A61P9/00—Drugs for disorders of the cardiovascular system
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Otolaryngology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Communicable Diseases (AREA)
AT04709303T 2003-02-19 2004-02-09 Für die therapie geeignete triazolverbindungen ATE349449T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0303852.8A GB0303852D0 (en) 2003-02-19 2003-02-19 Triazole compounds useful in therapy
GBGB0317227.7A GB0317227D0 (en) 2003-07-23 2003-07-23 Treatment of male sexual dysfunction

Publications (1)

Publication Number Publication Date
ATE349449T1 true ATE349449T1 (de) 2007-01-15

Family

ID=34889119

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04709303T ATE349449T1 (de) 2003-02-19 2004-02-09 Für die therapie geeignete triazolverbindungen

Country Status (25)

Country Link
EP (1) EP1597260B1 (enExample)
JP (2) JP4033886B2 (enExample)
KR (1) KR100750028B1 (enExample)
AP (1) AP2005003376A0 (enExample)
AT (1) ATE349449T1 (enExample)
AU (1) AU2004213242B2 (enExample)
BR (1) BRPI0407676A (enExample)
CA (1) CA2516557C (enExample)
DE (1) DE602004003914T2 (enExample)
DK (1) DK1597260T3 (enExample)
EA (1) EA009460B1 (enExample)
EC (1) ECSP055973A (enExample)
ES (1) ES2277237T3 (enExample)
GE (1) GEP20074089B (enExample)
HR (1) HRP20050681A2 (enExample)
IS (1) IS2450B (enExample)
MA (1) MA27712A1 (enExample)
MX (1) MXPA05008923A (enExample)
NO (1) NO20054053L (enExample)
OA (1) OA13029A (enExample)
PL (1) PL378747A1 (enExample)
PT (1) PT1597260E (enExample)
RS (1) RS20050638A (enExample)
SI (1) SI1597260T1 (enExample)
TN (1) TNSN05200A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008133288A1 (ja) * 2007-04-25 2008-11-06 Daiichi Sankyo Company, Limited 三環性アリール化合物
WO2011058193A1 (en) * 2009-11-16 2011-05-19 Mellitech [1,5]-diazocin derivatives
US8420633B2 (en) * 2010-03-31 2013-04-16 Hoffmann-La Roche Inc. Aryl-cyclohexyl-tetraazabenzo[e]azulenes
US8461151B2 (en) * 2010-04-13 2013-06-11 Hoffmann-La Roche Inc. Aryl-/heteroaryl-cyclohexenyl-tetraazabenzo[e]azulenes
US8492376B2 (en) * 2010-04-21 2013-07-23 Hoffmann-La Roche Inc. Heteroaryl-cyclohexyl-tetraazabenzo[e]azulenes
US8481528B2 (en) * 2010-04-26 2013-07-09 Hoffmann-La Roche Inc. Heterobiaryl-cyclohexyl-tetraazabenzo[e]azulenes
US9006450B2 (en) * 2010-07-01 2015-04-14 Boehringer Ingelheim International Gmbh Compounds, pharmaceutical compositions and uses thereof
HRP20210966T1 (hr) * 2013-12-05 2021-09-17 F. Hoffmann - La Roche Ag Sinteza trans-8-kloro-5-metil-1-[4-(piridin-2-iloksi)-cikloheksil]-5,6-dihidro-4h-2,3,5,10b-tetraaza­benzo[e]azulena i njegovih kristalnih oblika
HU231206B1 (hu) * 2017-12-15 2021-10-28 Richter Gedeon Nyrt. Triazolobenzazepinek

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8823475D0 (en) * 1988-10-06 1988-11-16 Merck Sharp & Dohme Chemical compounds
US5438035A (en) * 1994-06-24 1995-08-01 American Cyanamid Company Methods for controlling undesirable plant species with benzodiazepine compounds
US5753648A (en) * 1995-01-17 1998-05-19 American Cyanamid Company Tricyclic benzazepine vasopressin antagonists
HUP9904514A3 (en) * 1996-11-01 2000-10-30 Wyeth Corp 5h-pyrrolo[2,1-c][1,4]-benzodiazepin 3-carboxamide derivatives, process for their preparation, their use and pharmaceutical compositions containing them
TR200102069T2 (tr) * 1999-01-19 2001-11-21 Ortho-Mcneil Pharmaceutical, Inc. Vasopresin reseptörü antagonistleri olarak trisiklik benzodiazepinler.
US7109193B2 (en) * 2001-04-12 2006-09-19 Wyeth Tricyclic diazepines tocolytic oxytocin receptor antagonists
GB0224919D0 (en) * 2002-10-25 2002-12-04 Pfizer Ltd Triazole compounds useful in therapy

Also Published As

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EA200501136A1 (ru) 2006-06-30
BRPI0407676A (pt) 2006-03-01
PT1597260E (pt) 2007-01-31
SI1597260T1 (sl) 2007-04-30
IS2450B (is) 2008-11-15
OA13029A (en) 2006-11-10
HRP20050681A2 (en) 2005-12-31
DE602004003914T2 (de) 2007-05-31
KR100750028B1 (ko) 2007-08-16
ECSP055973A (es) 2006-01-16
JP2007045838A (ja) 2007-02-22
DK1597260T3 (da) 2007-04-02
RS20050638A (sr) 2007-12-31
IS7957A (is) 2005-07-25
JP2006517921A (ja) 2006-08-03
TNSN05200A1 (fr) 2007-06-11
AU2004213242B2 (en) 2007-04-19
AU2004213242A1 (en) 2004-09-02
DE602004003914D1 (de) 2007-02-08
EP1597260B1 (en) 2006-12-27
EA009460B1 (ru) 2007-12-28
ES2277237T3 (es) 2007-07-01
MXPA05008923A (es) 2006-03-09
PL378747A1 (pl) 2006-05-15
KR20050106443A (ko) 2005-11-09
NO20054053L (no) 2005-10-31
AP2005003376A0 (en) 2005-09-30
EP1597260A1 (en) 2005-11-23
GEP20074089B (en) 2007-04-10
JP4033886B2 (ja) 2008-01-16
CA2516557A1 (en) 2004-09-02
MA27712A1 (fr) 2006-01-02
CA2516557C (en) 2008-11-18
NO20054053D0 (no) 2005-08-31

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