GEP20074089B - Triazole compounds useful in therapy - Google Patents
Triazole compounds useful in therapyInfo
- Publication number
- GEP20074089B GEP20074089B GEAP20048945A GEAP2004008945A GEP20074089B GE P20074089 B GEP20074089 B GE P20074089B GE AP20048945 A GEAP20048945 A GE AP20048945A GE AP2004008945 A GEAP2004008945 A GE AP2004008945A GE P20074089 B GEP20074089 B GE P20074089B
- Authority
- GE
- Georgia
- Prior art keywords
- therapy
- compounds useful
- triazole compounds
- pharmaceutical compositions
- useful
- Prior art date
Links
- -1 Triazole compounds Chemical class 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- 206010013935 Dysmenorrhoea Diseases 0.000 abstract 1
- 201000009273 Endometriosis Diseases 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
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-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Ophthalmology & Optometry (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Cardiology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Gynecology & Obstetrics (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Otolaryngology (AREA)
- Rheumatology (AREA)
- Pregnancy & Childbirth (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Child & Adolescent Psychology (AREA)
- Oncology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0303852.8A GB0303852D0 (en) | 2003-02-19 | 2003-02-19 | Triazole compounds useful in therapy |
| GBGB0317227.7A GB0317227D0 (en) | 2003-07-23 | 2003-07-23 | Treatment of male sexual dysfunction |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GEP20074089B true GEP20074089B (en) | 2007-04-10 |
Family
ID=34889119
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GEAP20048945A GEP20074089B (en) | 2003-02-19 | 2004-02-09 | Triazole compounds useful in therapy |
Country Status (25)
| Country | Link |
|---|---|
| EP (1) | EP1597260B1 (enExample) |
| JP (2) | JP4033886B2 (enExample) |
| KR (1) | KR100750028B1 (enExample) |
| AP (1) | AP2005003376A0 (enExample) |
| AT (1) | ATE349449T1 (enExample) |
| AU (1) | AU2004213242B2 (enExample) |
| BR (1) | BRPI0407676A (enExample) |
| CA (1) | CA2516557C (enExample) |
| DE (1) | DE602004003914T2 (enExample) |
| DK (1) | DK1597260T3 (enExample) |
| EA (1) | EA009460B1 (enExample) |
| EC (1) | ECSP055973A (enExample) |
| ES (1) | ES2277237T3 (enExample) |
| GE (1) | GEP20074089B (enExample) |
| HR (1) | HRP20050681A2 (enExample) |
| IS (1) | IS2450B (enExample) |
| MA (1) | MA27712A1 (enExample) |
| MX (1) | MXPA05008923A (enExample) |
| NO (1) | NO20054053L (enExample) |
| OA (1) | OA13029A (enExample) |
| PL (1) | PL378747A1 (enExample) |
| PT (1) | PT1597260E (enExample) |
| RS (1) | RS20050638A (enExample) |
| SI (1) | SI1597260T1 (enExample) |
| TN (1) | TNSN05200A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008133288A1 (ja) * | 2007-04-25 | 2008-11-06 | Daiichi Sankyo Company, Limited | 三環性アリール化合物 |
| CN102812011A (zh) * | 2009-11-16 | 2012-12-05 | 梅利科技公司 | [1,5]-二氮杂环辛间四烯衍生物 |
| US8420633B2 (en) * | 2010-03-31 | 2013-04-16 | Hoffmann-La Roche Inc. | Aryl-cyclohexyl-tetraazabenzo[e]azulenes |
| US8461151B2 (en) * | 2010-04-13 | 2013-06-11 | Hoffmann-La Roche Inc. | Aryl-/heteroaryl-cyclohexenyl-tetraazabenzo[e]azulenes |
| US8492376B2 (en) * | 2010-04-21 | 2013-07-23 | Hoffmann-La Roche Inc. | Heteroaryl-cyclohexyl-tetraazabenzo[e]azulenes |
| US8481528B2 (en) * | 2010-04-26 | 2013-07-09 | Hoffmann-La Roche Inc. | Heterobiaryl-cyclohexyl-tetraazabenzo[e]azulenes |
| US9006450B2 (en) | 2010-07-01 | 2015-04-14 | Boehringer Ingelheim International Gmbh | Compounds, pharmaceutical compositions and uses thereof |
| KR102384629B1 (ko) * | 2013-12-05 | 2022-04-11 | 에프. 호프만-라 로슈 아게 | 트랜스-8-클로로-5-메틸-1-[4-(피리딘-2-일옥시)-사이클로헥실]-5,6-다이하이드로-4H-2,3,5,10b-테트라아자-벤조[e]아줄렌 및 그의 결정 형태의 합성 |
| HU231206B1 (hu) * | 2017-12-15 | 2021-10-28 | Richter Gedeon Nyrt. | Triazolobenzazepinek |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8823475D0 (en) * | 1988-10-06 | 1988-11-16 | Merck Sharp & Dohme | Chemical compounds |
| US5438035A (en) * | 1994-06-24 | 1995-08-01 | American Cyanamid Company | Methods for controlling undesirable plant species with benzodiazepine compounds |
| US5753648A (en) * | 1995-01-17 | 1998-05-19 | American Cyanamid Company | Tricyclic benzazepine vasopressin antagonists |
| KR20000052978A (ko) * | 1996-11-01 | 2000-08-25 | 이곤 이 버그 | 5Ｈ-피롤로[2,1-ｃ][1,4]-벤조디아제핀의 3-카복스아미드 유도체 |
| HU229074B1 (en) * | 1999-01-19 | 2013-07-29 | Ortho Mcneil Pharm Inc | Tricyclic benzodiazepines as vasopressin receptor antagonists |
| US7109193B2 (en) * | 2001-04-12 | 2006-09-19 | Wyeth | Tricyclic diazepines tocolytic oxytocin receptor antagonists |
| GB0224919D0 (en) * | 2002-10-25 | 2002-12-04 | Pfizer Ltd | Triazole compounds useful in therapy |
-
2004
- 2004-02-09 AP AP2005003376A patent/AP2005003376A0/xx unknown
- 2004-02-09 AT AT04709303T patent/ATE349449T1/de not_active IP Right Cessation
- 2004-02-09 MX MXPA05008923A patent/MXPA05008923A/es active IP Right Grant
- 2004-02-09 AU AU2004213242A patent/AU2004213242B2/en not_active Ceased
- 2004-02-09 KR KR1020057015408A patent/KR100750028B1/ko not_active Expired - Fee Related
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- 2004-02-09 HR HR20050681A patent/HRP20050681A2/hr not_active Application Discontinuation
- 2004-02-09 GE GEAP20048945A patent/GEP20074089B/en unknown
- 2004-02-09 EP EP04709303A patent/EP1597260B1/en not_active Expired - Lifetime
- 2004-02-09 PT PT04709303T patent/PT1597260E/pt unknown
- 2004-02-09 JP JP2006500323A patent/JP4033886B2/ja not_active Expired - Fee Related
- 2004-02-09 PL PL378747A patent/PL378747A1/pl not_active Application Discontinuation
- 2004-02-09 EA EA200501136A patent/EA009460B1/ru unknown
- 2004-02-09 OA OA1200500229A patent/OA13029A/en unknown
- 2004-02-09 SI SI200430160T patent/SI1597260T1/sl unknown
- 2004-02-09 DK DK04709303T patent/DK1597260T3/da active
- 2004-02-09 RS RSP-2005/0638A patent/RS20050638A/sr unknown
- 2004-02-09 BR BRPI0407676-1A patent/BRPI0407676A/pt not_active IP Right Cessation
- 2004-02-09 DE DE602004003914T patent/DE602004003914T2/de not_active Expired - Fee Related
- 2004-02-09 ES ES04709303T patent/ES2277237T3/es not_active Expired - Lifetime
-
2005
- 2005-07-25 IS IS7957A patent/IS2450B/is unknown
- 2005-08-19 MA MA28447A patent/MA27712A1/fr unknown
- 2005-08-19 TN TNP2005000200A patent/TNSN05200A1/fr unknown
- 2005-08-19 EC EC2005005973A patent/ECSP055973A/es unknown
- 2005-08-31 NO NO20054053A patent/NO20054053L/no not_active Application Discontinuation
-
2006
- 2006-10-11 JP JP2006277701A patent/JP2007045838A/ja not_active Withdrawn
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