ATE455768T1 - Triazolsubstituierte aminobenzophenonverbindungen - Google Patents

Triazolsubstituierte aminobenzophenonverbindungen

Info

Publication number
ATE455768T1
ATE455768T1 AT05804019T AT05804019T ATE455768T1 AT E455768 T1 ATE455768 T1 AT E455768T1 AT 05804019 T AT05804019 T AT 05804019T AT 05804019 T AT05804019 T AT 05804019T AT E455768 T1 ATE455768 T1 AT E455768T1
Authority
AT
Austria
Prior art keywords
triazole substituted
aminobenzophenone compounds
substituted aminobenzophenone
compounds
triazole
Prior art date
Application number
AT05804019T
Other languages
English (en)
Inventor
Erik Ottosen
Original Assignee
Leo Pharma As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharma As filed Critical Leo Pharma As
Application granted granted Critical
Publication of ATE455768T1 publication Critical patent/ATE455768T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • C07D249/06—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles with aryl radicals directly attached to ring atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4192—1,2,3-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Communicable Diseases (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT05804019T 2004-12-13 2005-11-28 Triazolsubstituierte aminobenzophenonverbindungen ATE455768T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US63500004P 2004-12-13 2004-12-13
DKPA200401942 2004-12-16
PCT/DK2005/000757 WO2006063585A1 (en) 2004-12-13 2005-11-28 Triazole substituted aminobenzophenone compounds

Publications (1)

Publication Number Publication Date
ATE455768T1 true ATE455768T1 (de) 2010-02-15

Family

ID=37715934

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05804019T ATE455768T1 (de) 2004-12-13 2005-11-28 Triazolsubstituierte aminobenzophenonverbindungen

Country Status (23)

Country Link
US (1) US8293772B2 (de)
EP (1) EP1828148B1 (de)
JP (1) JP5015005B2 (de)
KR (1) KR101260236B1 (de)
CN (1) CN101115728B (de)
AR (1) AR051792A1 (de)
AT (1) ATE455768T1 (de)
AU (1) AU2005316034B2 (de)
BR (1) BRPI0518993A2 (de)
CA (1) CA2590479A1 (de)
DE (1) DE602005019093D1 (de)
DK (1) DK1828148T3 (de)
ES (1) ES2341473T3 (de)
HR (1) HRP20100225T1 (de)
IL (1) IL183513A0 (de)
MX (1) MX2007006739A (de)
NO (1) NO20073574L (de)
PL (1) PL1828148T3 (de)
PT (1) PT1828148E (de)
RU (1) RU2394818C2 (de)
UA (1) UA90698C2 (de)
WO (1) WO2006063585A1 (de)
ZA (1) ZA200704809B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2346646T5 (es) * 2002-05-30 2018-02-15 The Scripps Research Institute Ligación catalizada con cobre de azidas y acetilenos
WO2007148074A1 (en) * 2006-06-21 2007-12-27 Hammersmith Imanet Limited Chemical methods and apparatus
US8080540B2 (en) 2006-09-19 2011-12-20 Abbott Products Gmbh Therapeutically active triazoles and their use
KR100932093B1 (ko) 2006-09-27 2009-12-16 주식회사종근당 미세소관 형성 저해제로서 유용한 벤조페논 유도체
US8288367B2 (en) 2006-11-30 2012-10-16 Solvay Pharmaceuticals Gmbh Substituted estratriene derivatives as 17BETA HSD inhibitors
JP4656674B2 (ja) * 2007-12-18 2011-03-23 アクテリオン ファーマシューティカルズ リミテッド アミノトリアゾール誘導体
PT2272845E (pt) 2008-03-26 2015-06-01 Chong Kun Dang Pharm Corp Derivados de benzofenona-tiazole úteis para inibir a formação de microtúbulos e método para produzir os mesmos
US9029408B2 (en) 2008-06-16 2015-05-12 Gtx, Inc. Compounds for treatment of cancer
US8822513B2 (en) 2010-03-01 2014-09-02 Gtx, Inc. Compounds for treatment of cancer
US9447049B2 (en) 2010-03-01 2016-09-20 University Of Tennessee Research Foundation Compounds for treatment of cancer
DK2959900T3 (en) 2008-06-16 2017-06-26 Univ Tennessee Res Found CONNECTION TO TREATMENT OF CANCER
CA2785254A1 (en) 2009-12-22 2011-06-30 Leo Pharma A/S Pharmaceutical composition comprising solvent mixture and a vitamin d derivative or analogue
CA2785251A1 (en) 2009-12-22 2011-06-30 Leo Pharma A/S Cutaneous composition comprising vitamin d analogue and a mixture of solvent and surfactants
BR112012015449B1 (pt) 2009-12-22 2021-09-28 Leo Pharma A/S Suspensão de monoidrato de calcipotriol, e, processo para preparar nanocristais de monoidrato de calcipotriol
US8912184B1 (en) 2010-03-01 2014-12-16 Alzheimer's Institute Of America, Inc. Therapeutic and diagnostic methods
EP3064204A1 (de) 2010-03-01 2016-09-07 GTx, Inc. Verbindungen zur behandlung von krebs
KR101666759B1 (ko) * 2015-08-06 2016-10-18 경북대학교 산학협력단 1-벤조피란메틸-1h-1,2,3-트리아졸 유도체 및 이의 용도
CN106632285B (zh) * 2016-11-23 2019-11-01 河南师范大学 一种齐多夫定-1,2,3-三氮唑类化合物的合成方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9701453D0 (en) 1997-01-24 1997-03-12 Leo Pharm Prod Ltd Aminobenzophenones
SI1210320T1 (en) 1999-07-16 2005-02-28 Leo Pharma A/S Aminobenzophenones as inhibitors of il-1beta and tnf-alpha
WO2001005745A1 (en) 1999-07-16 2001-01-25 Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) AMINOBENZOPHENONES AS INHIBITORS OF IL-1β AND TNF-$g(a)
DE60005689T2 (de) 1999-07-16 2004-08-05 Leo Pharma A/S Neue aminobenzophenone
JP2003505363A (ja) 1999-07-16 2003-02-12 レオ・ファーマ・アクティーゼルスカブ ＩＬ−１βおよびＴＮＦ−αの抑制剤としてのアミノベンゾフェノン
CA2379286A1 (en) 1999-07-16 2001-01-25 Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktionsa Ktieselskab) Aminobenzophenones as inhibitors of il-1.beta. and tnf-.alpha.
EP1237845B1 (de) 1999-12-06 2007-05-23 Leo Pharma A/S Aminobenzophenone als inhibitoren von il-1beta und tnf-alpha
WO2001090074A2 (en) 2000-05-22 2001-11-29 Leo Pharma A/S BENZOPHENONES AS INHIBITORS OF IL-1β AND TNF-$g(a)
GB0107368D0 (en) 2001-03-23 2001-05-16 Novartis Ag Organic compounds
US20030073832A1 (en) 2001-04-10 2003-04-17 Havez Sophie Elisabeth Novel aminophenyl ketone derivatives
CN100347151C (zh) 2001-08-28 2007-11-07 利奥制药有限公司 新的氨基苯酰苯类化合物
PL377377A1 (pl) 2002-12-20 2006-02-06 Leo Pharma A/S Nowe związki aminobenzofenonu
RU2396250C2 (ru) * 2003-07-24 2010-08-10 Лео Фарма А/С Новые производные аминобензофенона
US20090313239A1 (en) 2008-06-16 2009-12-17 Microsoft Corporation Adaptive Visual Similarity for Text-Based Image Search Results Re-ranking

Also Published As

Publication number Publication date
CA2590479A1 (en) 2006-06-22
PL1828148T3 (pl) 2010-08-31
HRP20100225T1 (hr) 2010-07-31
CN101115728B (zh) 2012-12-19
JP5015005B2 (ja) 2012-08-29
AU2005316034B2 (en) 2012-01-19
RU2007126648A (ru) 2009-01-20
BRPI0518993A2 (pt) 2008-12-23
AR051792A1 (es) 2007-02-07
NO20073574L (no) 2007-07-10
ES2341473T3 (es) 2010-06-21
EP1828148A1 (de) 2007-09-05
US20060128766A1 (en) 2006-06-15
RU2394818C2 (ru) 2010-07-20
AU2005316034A1 (en) 2006-06-22
DE602005019093D1 (de) 2010-03-11
PT1828148E (pt) 2010-05-04
EP1828148B1 (de) 2010-01-20
MX2007006739A (es) 2007-08-02
DK1828148T3 (da) 2010-05-17
WO2006063585A1 (en) 2006-06-22
KR20070095945A (ko) 2007-10-01
CN101115728A (zh) 2008-01-30
UA90698C2 (en) 2010-05-25
IL183513A0 (en) 2007-09-20
JP2008523115A (ja) 2008-07-03
KR101260236B1 (ko) 2013-05-06
ZA200704809B (en) 2008-08-27
US8293772B2 (en) 2012-10-23

Similar Documents

Publication Publication Date Title
ATE455768T1 (de) Triazolsubstituierte aminobenzophenonverbindungen
DK1605897T3 (da) Polyethelen-glycol-link-glp-1-forbindelser
IS8323A (is) Ný amínóbensófenónefnasambönd
ATE404546T1 (de) Substituierte n-sulfonylaminobenzyl-2- phenoxyacetamidverbindungen
IS8089A (is) Efnasambönd
ITMI20042238A1 (it) Composti per fluoropolirterei
DE502005008002D1 (de) Bleichmittel-mischungen
NO20031736D0 (no) Forbindelser
ATE384719T1 (de) Dioxazinyl-substituierte thienylsulfonylaminocarbonylverbindungen
SE0400022D0 (sv) New compounds
SE0402103D0 (sv) Novel compounds
ATE373956T1 (de) Fungizide mischungen
SE0400254D0 (sv) New compounds
SE0402391D0 (sv) Novelheterocyclic compounds
DOP2004000959A (es) Compuestos
HK1117152A1 (en) Triazole substituted aminobenzophenone compounds
SI1828148T1 (sl) S triazolom nadomeĺ äśeni aminobenzofenonski sestavki
SE0401667D0 (sv) New compounds
SE0400227D0 (sv) New compounds
SE0401658D0 (sv) New compounds
SE0400044D0 (sv) New compounds
SE0400102D0 (sv) New compounds
SE0401324D0 (sv) New compounds
SE0401332D0 (sv) New compounds
SE0402681D0 (sv) New compounds

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1828148

Country of ref document: EP